FB2025_01 , released February 20, 2025
Gene Group: DIPEPTIDYL PEPTIDASES IV
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General Information
Name
DIPEPTIDYL PEPTIDASES IV
Species
D. melanogaster
Symbol
DPPIV
FlyBase ID
FBgg0001535
Date last reviewed
2020-06-12
Number of members
5
Description
Description
Dipeptidyl peptidase IV (DPPIV) belongs to the MEROPS S9 family, subfamily B, and is a highly specific dipeptidyl aminopeptidase. It is characterized by the release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is proline, provided Zaa is neither proline nor hydroxyproline. DPPIV is important in the processing of a variety of biologically active oligopeptides and also in the activation of signal transduction and cell matrix adherence processes. (Adapted from FBrf0194259.)
Notes on Group
Source Material
The DIPEPTIDYL PEPTIDASES IV Gene Group has been compiled using the following publication(s): Chihara et al., 2005 and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
dipeptidyl-peptidase activity
serine-type aminopeptidase activity
Biological Process
proteolysis
Cellular Component
Related Gene Groups
Parent group(s)
S9 SERINE PEPTIDASES
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3744
(FlyBase, 2017-, Chihara et al., 2005, Rawlings and Barrett, 1996-)
CG11034
(FlyBase, 2017-, Chihara et al., 2005, Rawlings and Barrett, 1996-)
CG17684
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
Dpp10
Dipeptidyl peptidase 10
(FlyBase, 2017-, Chihara et al., 2005, Rawlings and Barrett, 1996-)
ome
omega
(FlyBase, 2017-, Chihara et al., 2005, Rawlings and Barrett, 1996-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
DPPIV
S9B
DIPEPTIDYL PEPTIDASES IV
Secondary FlyBase ID(s)
References (4)