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General Information
Name
TNFα-Eiger Signaling Pathway Core Components
Species
D. melanogaster
Symbol
TNF-C
FlyBase ID
FBgg0001561
Date last reviewed
2021-07-15
Number of members
12
Description
Description
The Tumor Necrosis Factor α (TNFα) signaling pathway is activated by Eiger (egr) binding to a member of the TNF receptor superfamily. The signal is primarily transduced via the Jun N-terminal kinase (JNK) cascade, leading to cell death. (Adapted from FBrf0225608.)
Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
Related Gene Groups
Physical Interaction Network
Members (12)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
TNF-C
TNFα-Eiger Signaling Pathway Core Components
Secondary FlyBase ID(s)
References (24)