FB2025_01 , released February 20, 2025
Gene Group: CYSTEINE-TYPE OTU DEUBIQUITINASES
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General Information
Name
CYSTEINE-TYPE OTU DEUBIQUITINASES
Species
D. melanogaster
Symbol
OTU-DUB-C
FlyBase ID
FBgg0001680
Date last reviewed
2021-02-05
Number of members
5
Description
Description
Cysteine-type OTU deubiquitinases belong to the ovarian tumour (OTU) sub-family of deubiquitinases and catalyze the removal of ubiquitin from ubiquitin chains and ubiquitinated proteins. They have a central cysteine in the catalytic triad within their OTU domain. (Adapted from FBrf0230214.)
Notes on Group
Source Material
The CYSTEINE-TYPE OTU DEUBIQUITINASES Gene Group has been compiled using the following publication(s): Páhi et al., 2022, Badmos et al., 2021, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
cysteine-type deubiquitinase activity
Biological Process
protein deubiquitination
Cellular Component
Enzymatic activity
Enzyme name (EC)
ubiquitinyl hydrolase 1 (3.4.19.12)
Related Gene Groups
Parent group(s)
CYSTEINE-TYPE DEUBIQUITINASES
Other related group(s)
SERINE-TYPE OTU DEUBIQUITINASES
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG4968
(Páhi et al., 2022, Badmos et al., 2021, FlyBase, 2017-, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, Rawlings and Barrett, 1996-)
Duba
Deubiquitinating enzyme A
(Páhi et al., 2022, Badmos et al., 2021, FlyBase, 2017-, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, Rawlings and Barrett, 1996-)
Otud6
OTU deubiquitinase 6
(Páhi et al., 2022, Badmos et al., 2021, FlyBase, 2017-, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, Rawlings and Barrett, 1996-)
trbd
trabid
(Páhi et al., 2022, Badmos et al., 2021, FlyBase, 2017-, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, Rawlings and Barrett, 1996-)
Yod1
Yod1 deubiquitinase
(Páhi et al., 2022, Badmos et al., 2021, FlyBase, 2017-, Clague et al., 2013, Tsou et al., 2012, Zhang et al., 2012, Rawlings and Barrett, 1996-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
OTU-DUB-C
CYSTEINE-TYPE OTU DEUBIQUITINASES
Secondary FlyBase ID(s)
References (8)