FB2025_01 , released February 20, 2025
Gene Group: PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS
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General Information
Name
PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS
Species
D. melanogaster
Symbol
PAM
FlyBase ID
FBgg0001908
Date last reviewed
2024-01-05
Number of members
6
Description
Description
The presequence translocase-associated motor (PAM) is a subcomplex of the TIM23 complex. It is required to drive the ATP hydrolysis-dependent translocation of proteins across the inner mitochondrial membrane for import into the matrix. (Adapted from PMID:32074073.)
Notes on Group
Source Material
The PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS Gene Group has been compiled using the following publication(s): Kaneko, 2022, Vedelek et al., 2018, Yoon et al., 2017, Roy et al., 2012, Tan et al., 2009, Sardiello et al., 2003.6.11, and Becker et al., 2001 .
Key Gene Ontology (GO) terms
Molecular Function
protein-transporting ATPase activity
Biological Process
protein import into mitochondrial matrix
Cellular Component
PAM complex, Tim23 associated import motor
Related Gene Groups
Parent group(s)
TIM23 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE COMPLEX SUBUNITS
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
blp
black pearl
l(3)01618
(Roy et al., 2012, Becker et al., 2001)
CG1409
(Vedelek et al., 2018, Becker et al., 2001)
CG7394
(Becker et al., 2001)
CG11779
(Sardiello et al., 2003.6.11)
Hsc70-5
Heat shock protein 70 cognate 5
Hsc5, Hsc70, Heat shock protein cognate 5, l(2)k04907, Heat shock 70 kDa protein cognate 5
(Kaneko, 2022, Tan et al., 2009)
Roe1
Roe1
(Yoon et al., 2017, Tan et al., 2009)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PAM
PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS
Secondary FlyBase ID(s)
References (8)