FB2025_02 , released April 17, 2025
Complex: MITOCHONDRIAL DNA REPLISOME
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General Information
Name
MITOCHONDRIAL DNA REPLISOME
Species
D. melanogaster
Symbol
MT-REP
FlyBase ID
FBgg0001975
Date last reviewed
2024-06-26
Number of members
4
Description
Description
The mitochondrial DNA (mtDNA) replisome is multiprotein assembly required for the replication of mitochondrial DNA. The complex catalyzes the unwinding and strand synthesis of mtDNA. (Adapted from PMID:38884788.)
Notes on Group

Unlike canonical DNA replication, a specific mitochondrial DNA primase has not been identified. Instead, priming is coupled to mitochondrial RNA polymerase-dependent transcription (PMID:38884788, FBrf0253515).

Source Material
The MITOCHONDRIAL DNA REPLISOME Gene Group has been compiled using the following publication(s): Rodrigues et al., 2022 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mitochondrial DNA replication
Cellular Component
mitochondrial chromosome
replisome
Related Gene Groups
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
MT-REP
MITOCHONDRIAL DNA REPLISOME
mtDNA replisome
Secondary FlyBase ID(s)
References (2)