FB2025_01 , released February 20, 2025
Complex: INTEGRATOR COMPLEX
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General Information
Name
INTEGRATOR COMPLEX
Species
D. melanogaster
Symbol
INT
FlyBase ID
FBgg0002030
Date last reviewed
2024-09-19
Number of members
15
Description
Description
The Integrator complex is an RNA Polymerase II (Pol II)-associated endonucleolytic complex that mediates 3'-end generation of small nuclear RNAs (snRNAs) and other non-coding RNAs, and modulates Pol II promoter-proximal pausing and transcript elongation. (Adapted from PMID:36180603.)
Notes on Group
Source Material
The INTEGRATOR COMPLEX Gene Group has been compiled using the following publication(s): Lin et al., 2024 .
Key Gene Ontology (GO) terms
Molecular Function
RNA endonuclease activity
Biological Process
RNA processing
Cellular Component
integrator complex
nucleus
Related Gene Groups
Members (15)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
asun
asunder
Mat89Bb, IntS13
(Lin et al., 2024)
CG5274
(Lin et al., 2024)
defl
deflated
IntS7
(Lin et al., 2024)
IntS1
Integrator 1
(Lin et al., 2024)
IntS2
Integrator 2
(Lin et al., 2024)
IntS3
Integrator 3
(Lin et al., 2024)
IntS4
Integrator 4
l(1)G0095
(Lin et al., 2024)
IntS6
Integrator 6
(Lin et al., 2024)
IntS8
Integrator 8
EG:EG0003.5, l(2)SH1314
(Lin et al., 2024)
IntS9
Integrator 9
(Lin et al., 2024)
IntS10
Integrator 10
(Lin et al., 2024)
IntS11
Integrator 11
(Lin et al., 2024)
IntS12
Integrator 12
Int12
(Lin et al., 2024)
IntS14
Integrator 14
(Lin et al., 2024)
omd
oocyte maintenance defects
IntS5
(Lin et al., 2024)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
INT
INTEGRATOR COMPLEX
Secondary FlyBase ID(s)
References (2)