FB2025_01 , released February 20, 2025
Gene Group: UNCHARACTERIZED TOM40 PARALOG
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General Information
Name
UNCHARACTERIZED TOM40 PARALOG
Species
D. melanogaster
Symbol
TOMM-U40
FlyBase ID
FBgg0002071
Date last reviewed
2025-01-16
Number of members
1
Description
Description
The 'uncharacterized Tom40 paralog' group contains CG4520. CG4520 has homology with Tom40 and the testis specific Tom40 subunit tomboy40, but unlike these paralogs there is no supporting evidence for it as a component of a mitochondrial translocase of the outer membrane (TOM) complex.
Notes on Group

CG4520 has been placed in a separate gene group as it is unclear whether this is a functional component of translocase of the outer membrane (TOM) complexes. It displays testis-specific expression and has homology with Tom40 and the testis specific Tom40 subunit tomboy40. However, Tom40 and tomboy40, which have both been shown to be components of TOM complexes, share 68% identity/80% similarity, whilst CG4520 shares less than 25% identity/45% similarity with Tom40/tomboy40. AlphaFold predicts a beta barrel structure.

Source Material
The UNCHARACTERIZED TOM40 PARALOG Gene Group has been compiled using the following publication(s): Attrill, 2025.1.17 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
TOMM-U40
UNCHARACTERIZED TOM40 PARALOG
Secondary FlyBase ID(s)
References (2)