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Gene Dmel\ac

General Information
Symbol	Dmel\ac	Species	D. melanogaster
Name	achaete	Annotation symbol	CG3796
Feature type	protein_coding_gene	FlyBase ID	FBgn0000022
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	X	Recombination map	1-0.0
Cytogenetic map	1A6-1A6	Sequence location	X:264,064..265,024 [+]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene achaete is referred to in FlyBase by the symbol ac (CG3796, FBgn0000022). It has the cytological map location 1A6. Its sequence location is X:264064..265024. Its molecular function is described as: specific RNA polymerase II transcription factor activity; DNA binding; transcription activator activity; transcription factor activity; transcription regulator activity. It is involved in the biological processes described with 11 unique terms, many of which group under: anatomical structure development; system development; regulation of biological process; regulation of metabolic process; nervous system development; central nervous system development; cell cycle; neuroblast fate commitment; organ development; multicellular organismal development; primary metabolic process; gamete generation; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. 44 alleles are reported. The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; postalar bristle; anterior orbital bristle; embryonic nervous system; acrostichal bristle; antennal segment; adult external prothorax. It has one annotated transcript and one annotated polypeptide.
External Summaries
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	ac: achaete ac: achaete From Bridges and Brehme, 1944, Carnegie Inst. Washington Publ. No. 552: 12. ac specifies the formation of the anterior and posterior dorsocentral, the posterior supra-alar (as does sc), the anterior vertical bristle, and in addition the acrostichal rows of microchaetae on the notum. Absence of bristles accompanied by absence of associated socket and underlying centrally projecting neuron (Stern, 1938, Genetics 23: 172-73). In addition mutant alleles of ac tend to remove the interocellar hairs and the hairs on the surface of the eye and a restricted subset of the campaniform sensilla on the wing blade (Leyns, Dambly-Chaudiere and Ghysen, 1989, Roux's Arch. Dev. Biol. 198: 227-32). Trichomes are not affected. ac deficiencies, e.g., In(1)y3PLsc8R, survive as fully mobile and fertile adults (Garcia-Bellido, 1979, Genetics 90: 491-529). A series of terminal deficiencies approaching the ac coding sequence from the left a few hundred base pairs at a time, when tested in heterozygotes with In(1)y3PLsc8R or Df(1)sc19, cause, with few exceptions, progressive loss of chaetae as the amount of deleted material increases; response of anterior verticals erratic. First effects of deficiencies noted with chromosomes broken 10 kb upstream of the transcription start site. Despite loss of most of the DNA upstream from the transcribed region, the phenotypes associated with these deletions still suppressed by emc and h (Ruiz-Gomez and Modolell, 1987, Genes Dev. 1: 1238-46). Deficiencies for ac act as suppressors of h (Sturtevant, 1970, Dev. Biol. 21: 48-63), whereas extra doses of ac+ enhance expression of h (Moscoso del Prado and Garcia-Bellido, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 242-51). Longitudinal stripes of expression on either side of the midline during gastrulation become internalized and segmented into four longitudinal rows of clusters of expressing cells at half-segment intervals. ac RNA undetectable in germ band at time of germ-band shortening. Several regions of high expression seen in cephalic region. Also expressed in posterior midgut rudiment (Romani, Campuzano, and Modolell, 1987, EMBO J. 6: 2085-92; Cabrera, Martinez-Arias, and Bate, 1987, Cell 50: 425-33). In third-instar larvae, expression in wing imaginal disks restricted to regions where precursors of cuticular organs specified by ac are known to reside (Romani, Campuzano, Macagno, and Modolell, 1989, Genes Dev. 3: 997-1007). ac1 Hypomorphic; phenotype of homozygous females weaker than in hemizygous females (Garcia-Bellido, 1979, Genetics 91: 491-520). Posterior dorsocentral bristles missing; also posterior supra-alar and anterior vertical bristles frequently missing. Anterior dorsocentrals displaced anteriorly (Claxton, 1969, Genetics 63: 883-96). Garcia-Bellido (1979) finds anterior dorsocentral bristles more strongly decreased than posterior dorsocentrals. Hairs usually fewer near position of posterior dorsocentrals; interocellar hairs invariably fewer, typically absent. Eyes partly devoid of hairs. Trichomes unaffected. Limited nonautonomy near the borders of somatic spots with respect both to numbers and positions of bristles and hairs (Stern, 1954, Am. Sci. 42: 212-47; Roberts, 1961, Genetics 46: 1241-43; Claxton, 1976, Genet. Res. 27: 11-22). ac partially suppresses h; Hw/ac = Hw/+ (Sturtevant, 1969). *ac2 Since ac2 and sc3 were for practical purposes inseparable by crossing over, the effect of ac2 alone could not be assessed. The double mutant removed all bristles except scutellars and postdorsocentrals. ac2/ac2 and ac2/+ suppress h (Sturtevant). Viability of males low; females nearly inviable. RK2. ac3 Posterior and usually anterior dorsocentrals lacking; other bristles wild type. Hairs removed from areas across rear and front edges of thorax, through mid-dorsal area, and between ocelli. ac3 even in ac3/+ heterozygotes exerts strong suppression on h (Sturtevant, 1970, Dev. Biol. 21: 48-61). RK2A. ac3B Low level of absence of dorsocentral bristles as well as microchaetae. Bristles normally removed by sc mutations not missing. Hw1 Males and heterozygous females have extra bristles on the head (especially occipitals), the notum and the mesopleurae; also extra bristles, including sensory ones and campaniform sensilla (Palka, Schubiger, and Hart, 1981, Nature 294: 447-49), along longitudinal veins and in membrane of wing. Classifiable in a single dose in triploids (Schultz, 1934, DIS 1: 55). Homozygous females more extreme; 110 extra chaetae on wing vs. 49.5 for Hw1/+; 11 on scutellum and postnotum vs. 0.7 in Hw/+ (Garcia-Bellido and Merriam, 1971, Proc. Nat. Acad. Sci. USA 68: 2222-26). Number of extra bristles inversely correlated with temperature (Ohn and Sheldon, 1970, Genetics 66: 517-40). Hw1/Hw1 females exhibit 40-80% wildtype viability and are agametic steriles; clones of homozygous germinal cells in Hw/+ females capable of producing progeny (Garcia-Bellido and Robbins, 1983, Genetics 103: 235-47); however, Garcia-Alonzo and Garcia-Bellido claim that their strain is no longer homozygous female sterile. Viability and fertility of Hw1/Y males and Hw1/+ females good. Hw1/Hw1 and _ autonomous in somatic clones until 8 hr before puparium formation; altering cellular genotype after that time is without effect owing to perdurance (Garcia-Bellido and Merriam). X-ray-induced full and partial revertants are frequently mutant for ac (Garcia-Alonzo and Garcia-Bellido). RK1 as male or heterozygous female. Hw2 Females homozygous for Hw2 show only occasional extra hairs along wings. Overlaps wild type. RK3A. Hw49c More extreme than Hw1. Homozygous female has doubling and tripling of many bristles, three or four extra dorsocentral bristles per side, extra wing veins, gap in posterior crossvein, and extra hairs on vein L2 and in wing cells. Width of mesonotum in region between dorsocentral bristles increased leading to increased numbers of acrostichal rows as well as extraneous extra microchaetae (Gottlieb, 1964, Genetics 49: 739-60); many lack one or more ocellar or postvertical macrochaetae (Stoddard, 1972, DIS 48: 137-38). Heterozygous female has normal bristles, extra hairs on L2 and L3 and in wing cells, and often an extra free vein from posterior crossvein; also extra acrostichal rows. Hw49c male much like homozygous female but bristle duplication less extreme. Low degree of non autonomy reported at junction between Hw49c/Hw49c and +/+ twin spots (Gottlieb). Male and heterozygous female fertile; homozygous female sterile. Revertants of Hw49c lose their dominant phenotypes; however they remain sc and may exhibit a weak ac phenotype or be lethal in combination with Df(1)sc19 (Garcia-Alonzo and Garcia-Bellido). Not suppressed by su(Hw). Hw49c and Oce act synergistically in removing head bristles but cancel each others effects on thorax in Hw/Oce females (Stoddard). ac, sc, and l(1)sc transcripts considerably more abundant than in wild type; also more generally expressed in wing disks than normal (Balcells et al.). RK1. Hw685 Df(1)Hw685/Df(1)sc19 generates lateral clusters of microchaetae on the scutellum and promotes differentiation of extra sensilla campaniformia on the dorsal radius of the wing, of microchaetae or other sensilla on wing vein 3, and occasional microchaetae on wing vein 2. Slight increases in numbers of microchaetae on notum as well. Displays a very weak achaete effect despite presumed homozygous deficiency for ac. Hwbap: Hairy wing-bristly abdominal pleura Nearly all abdominal segments have on the pleurae two rows of bristles, which are the same size as those on the sternites. Mutant-bearing flies have a row of bristles arising immediately posterior to each pigment band that are shorter than other tergite bristles. HwBS Spontaneous derivation of Hw1 with slightly weaker phenotype. Hw: Hairy wing Hw: Hairy wing Edith M. Wallace, unpublished. Gain of function alleles of ASC, which lead to the development of supernumerary bristles and hairs in all segments of the fly: in the prefrons, postfrons, postgena, and occipital regions of the head; in the preepisternum, episternum, anepisternum, scutum, scutellum, postnotum, wingblade, legs, humerus, and halteres of the thorax; and in the tergites, pleura, and sternites of the abdomen. Phenotype suppressed by three doses of h+ (Botas, Moscoso del Prado, and Garcia-Bellido, 1982, EMBO J. 1: 307-10) and enhanced by h, emc, and pyd (Neel, 1941, Genetics 26: 52-58; Moscoso del Prado and Garcia-Bellido, 1984, Wilhelm Roux's Arch Dev. Biol. 193: 242-45). Numbers of super numerary bristles reduced in da+ hemizygotes (Dambly-Chaudiere, Ghysen, Jan and Jan, 1988, Roux's Arch Dev. Biol. 97: 419-23).
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 1A6-1A6   Limits computationally determined from genome sequence between P{EP}CG17896EP1320&P{EP}EP1398 and P{EP}svrEP356&P{EP}argEP452
Experimentally Determined Cytological Location
Cytogenetic map Notes References 1B1-1B5 (determined by in situ hybridisation)   (Villares and Cabrera, 1987)
Experimentally Determined Recombination Data
Location	1-0.0
Left of (cM)	sc (Williamson et al., 1970)
Right of (cM)	l(1)1Ac (Deak et al., 1982)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References Overall orientation not stated: y? anon-1Be? ac? (Chia et al., 1986)
Gene Model & Products
Please see the GBrowse view of Dmel\ac for information on other features
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) ac-RA FBtr0070072  NM_057476   961   201
Additional Transcript Data & Comments
Reported size (kB)	1.1, 0.9 (northern blot) (Campuzano et al., 1986)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein ac-PA   FBpp0070071   22.8   201   7.72     NP_476824   AAF45498
Additional Polypeptide Data & Comments
Reported size (kD)	23 (kD predicted) (Villares and Cabrera, 1987)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0000022
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Achaete-scute transcription factor related (IPR015660) Basic helix-loop-helix dimerisation region bHLH (IPR001092) Helix-loop-helix DNA-binding (IPR011598) TRANSFAC - Eukaryotic transcription factors, their genomic binding sites, and DNA-binding profiles • R03719 R04159 T00005
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE003417 AAF45498   AF132808   AL023873 CAA19641   BT022154   CO319135   CO319752   CO340473   EC078539   EC235785   EC239019   EC250408   EC260329   M17120 AAA28312
UniProtKB/Swiss-Prot	P10083
UniProtKB/TrEMBL
Maps to	125H10 (FlyBase, 1992-)
Does NOT map to
Identified with	IP01413 (Hoskins et al., 2005) D1180 (BDGP Project Members, 1994-1999)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References aberration junction In(1)Hw[1+R1].bk1 X:261,107..262,725 comment=Aberration breakpoint mapped to a BglII-BglII restriction fragment; position of restriction fragment on reference sequence inferred by FlyBase curator. evidence=experimental linked_to=BglII-BglII_rfrag (Campuzano et al., 1986) protein binding site ac-protein_bind-1 X:263,752..263,769 bound_moiety=E(spl)-XP evidence=experimental bound_moiety=HLHm5-XP (Oellers et al., 1994, Bergman et al., 2004) regulatory region ac-reg_element-2 X:263,243..263,250 comment=E box T5E4 evidence=experimental (van Doren et al., 1991) regulatory region ac-reg_element-3 X:263,759..263,768 comment=bound by h protein and HLHm7 protein comment=h/E-1 site evidence=experimental (van Doren et al., 1994, Ohsako et al., 1994) regulatory region ac-reg_element-4 X:263,798..263,805 comment=E box T5E3 comment=Bound by heterodimers consisting of da protein and either ac protein, sc protein or l(1)sc protein. Important for tissue-specific expression. evidence=experimental (van Doren et al., 1991, van Doren et al., 1992) regulatory region ac-reg_element-5 X:263,866..263,873 comment=E box T5E2 comment=Bound by heterodimers consisting of da protein and either ac protein, sc protein or l(1)sc protein. Important for tissue-specific expression. evidence=experimental (van Doren et al., 1991, van Doren et al., 1992) regulatory region ac-reg_element-6 X:264,002..264,009 comment=E box T5E1 comment=Bound by heterodimers consisting of da protein and either ac protein, sc protein or l(1)sc protein. Important for tissue-specific expression. evidence=experimental (van Doren et al., 1991, van Doren et al., 1992)
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 53
Crossreferences	EPD - Eukarytoic Promoter Database, an annotated collection of POL II promoters • 16024
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference  embryonic stage  stomodeum (Romani et al., 1987)  embryonic stage  neuroblast (Cabrera et al., 1987)  embryonic stage  sensory organ mother cell (Ruiz-Gomez and Ghysen, 1993)  embryonic stage  posterior embryonic/larval midgut (Romani et al., 1987)  larval stage  proneural cluster (Cubas et al., 1991)  embryonic stage  embryonic stomatogastric nervous system (Cabrera et al., 1987)  embryonic stage | stage 9  neuroblast (Skeath and Carroll, 1992)  embryonic stage  posterior embryonic/larval midgut (Cabrera et al., 1987)  embryonic stage  neuroblast (Ruiz-Gomez and Ghysen, 1993)  embryonic stage  neurogenic region (Ruiz-Gomez and Ghysen, 1993)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage  sensory organ cell (Ruiz-Gomez and Ghysen, 1993)  larval stage | third instar  dorsal mesothoracic disc | restricted (Romani et al., 1989)  embryonic stage  midline (Romani et al., 1987)  embryonic stage  ectoderm (Romani et al., 1987)  embryonic stage  procephalon (Romani et al., 1987)  embryonic stage  larval optic lobe | presumptive (Cabrera et al., 1987)  embryonic stage  procephalic neuroblasts (Cabrera et al., 1987)  larval stage | third instar  sensillum precursor (Romani et al., 1989)  embryonic stage  embryonic central nervous system (Romani et al., 1987)  larval stage  dorsal mesothoracic disc (Cubas et al., 1991)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage  neurogenic region (Cabrera et al., 1987)  embryonic stage | stage 8  ectoderm (Skeath and Carroll, 1992)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage  cephalic furrow (Romani et al., 1987)  embryonic stage  embryonic peripheral nervous system (Ruiz-Gomez and Ghysen, 1993)  embryonic stage  labral segment (Romani et al., 1987)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference  larval stage | third instar  dorsal mesothoracic disc (Skeath and Carroll, 1991)  larval stage  dorsal mesothoracic disc (Cubas et al., 1991)  larval stage | third instar  sensory organ mother cell (Skeath and Carroll, 1991)  embryonic stage | stage 9-11  protocerebral neuroblast | subset (Urbach and Technau, 2003)  embryonic stage | stage 8-9  neuroblast NB3-5 (Doe, 1992)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  larval stage | third instar  proneural cluster (Skeath and Carroll, 1991)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage | stage 8-9  neuroblast NB7-4 (Doe, 1992)  larval stage  proneural cluster (Cubas et al., 1991)  larval stage | third instar  wing vein L5 (Skeath and Carroll, 1991)  embryonic stage | stage 8  ectoderm (Skeath and Carroll, 1992)  embryonic stage | stage 9-11  deuterocerebral neuroblast | subset (Urbach and Technau, 2003)  embryonic stage | stage 8-9  neuroblast NB7-1 (Doe, 1992)  larval stage | third instar  ectoderm (Skeath and Carroll, 1991)  embryonic stage | stage 8-10  neuroblast MP2 (Doe, 1992)  embryonic stage | stage 8-11  procephalic neuroblast | subset (Urbach et al., 2003)  larval stage | third instar  wing vein L1 (Skeath and Carroll, 1991)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  larval stage | third instar  wing vein L3 (Skeath and Carroll, 1991)  embryonic stage | stage 8-11  procephalic neurectoderm | restricted (Urbach et al., 2003)  embryonic stage | stage 9  neuroblast (Skeath and Carroll, 1992)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)  embryonic stage  neurectoderm (Skeath and Carroll, 1992)
Marker for
	sensillum precursor sensory mother cell &&of dorsal mesothoracic disc
Subcellular Localization
CV Term	nucleus (Skeath and Carroll, 1992)
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0000022 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0000022 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0000022 FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for ac Stage(s) 1-3 Stage(s) 4-6 Stage(s) 7-8 Stage(s) 9-10 Stage(s) 11-12 Stage(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable acHw-49c accami acsbm viable | good acHw-1 Other Phenotypes Allele wild-type ac+mPa visible ac3B acHw-1 visible | recessive ac1 ac2 ac3 ac3B ac4 acHw-1+R1 acHw-1+R3 acHw-1+R5 acHw-1 acHw-2 acHw-49c visible | dominant acHw-1 acHw-49c acHw-685 acHw-BS acHw-bap visible | adult stage ac3 acsbm visible | adult stage (with Df(1)sc-B57) accami Sterility Allele female sterile | recessive acHw-49c male sterile acHw-1+R1 fertile accami acsbm male fertile acHw-49c Phenotype manifest in Allele anterior dorsocentral bristle ac1 ac3 ac4 acsbm posterior dorsocentral bristle ac1 ac3 ac4 acsbm anterior supraalar bristle ac1 ac3B posterior supraalar bristle ac1 ac3 ac3B acsbm acrostichal bristle ac1 ac3 ac3B ac4 acHw-49c interocellar bristle ac1 ac3 interommatidial bristle ac1 mesothoracic tarsal bristle ac1 ac2 ac3 acHw-1 acHw-49c mesothoracic leg sensillum | ectopic ac1 ac2 mesothoracic leg sensillum ac3 dorsocentral bristle | precursor ac3 posterior supraalar bristle | precursor ac3 macrochaeta & leg ac3 microchaeta & leg ac3 adult thorax & microchaeta ac3 acsbm anterior orbital bristle ac3B anterior notopleural bristle ac3B humeral bristle ac3B postvertical bristle ac3B acHw-49c ocellar bristle ac3B acHw-49c presutural bristle ac3B anterior postalar bristle ac3B posterior postalar bristle ac3B scutellar bristle ac3B dorsocentral bristle ac3B acHw-49c microchaeta ac3B acHw-1 acHw-BS mesothoracic tarsal segment 1 acHw-1 acHw-49c macrochaeta | ectopic acHw-1 glial cell | ectopic acHw-1 wing & nerve acHw-1 nerve | ectopic acHw-1 antennal segment 3 acHw-1 mesothoracic tergum & macrochaeta | ectopic acHw-1 wing margin bristle | ectopic acHw-1 acHw-49c macrochaeta & head acHw-1 acHw-1+R1 acHw-1+R3 acHw-BS macrochaeta & thorax acHw-1 acHw-1+R1 acHw-1+R3 acHw-BS sensillum campaniformium acHw-1 acHw-BS wing acHw-1+R5 acHw-49c microchaeta & wing acHw-2 acHw-49c acT5-M scutum acHw-49c microchaeta & mesothoracic tergum | supernumerary acHw-49c neuron acHw-49c anterior sternopleural bristle acHw-49c macrochaeta acHw-49c acHw-49crv1 acHw-49crv4 wing vein acHw-49c posterior crossvein acHw-49c chaeta | ectopic acHw-49c wing vein | precursor acHw-49c sensory mother cell | ectopic acHw-49c sensory mother cell & dorsal mesothoracic disc acHw-49c microchaeta & scutum acHw-685 microchaeta & scutellum acHw-685 sensillum campaniformium of proximal dorsal radius acHw-685 sense organ & wing vein acHw-685 macrochaeta & abdominal tergite acHw-bap microchaeta & pleural membrane acHw-bap microchaeta | ectopic acT5-C acT5-M microchaeta & mesothoracic pleurum acT5-M posterior supraalar bristle (with Df(1)sc-B57) accami posterior notopleural bristle (with Df(1)sc-B57) accami anterior notopleural bristle (with Df(1)sc-B57) accami anterior postalar bristle (with Df(1)sc-B57) accami
Classical Alleles ( 25 )
For All Classical Alleles Show
Allele of ac Class Mutagen Stocks Known lesion ac+ 2 -- ac1 hypomorph spontaneous 32 Yes ac260-28 X ray 0 -- ac260-31 0 -- ac2 X ray 0 -- ac3 amorph X ray 0 Yes ac3B spontaneous 0 Yes ac4 X ray 1 -- ac4G P-element activity 0 Yes ac54e X ray 0 -- acHw-1+R1 X ray 0 Yes acHw-1+R3 X ray 0 Yes acHw-1+R5 X ray 0 Yes acHw-1 gain of function spontaneous 15 Yes acHw-2 spontaneous 1 -- acHw-49c <up>32</up>P 2 Yes acHw-49crv1 X ray 0 Yes acHw-49crv4 X ray 0 Yes acHw-685 0 -- acHw-BS spontaneous 0 Yes acHw-bap 0 -- accami amorph P-element activity 0 Yes acrv1 P-element activity 0 Yes acsbm P-element activity 0 Yes acunspecified 0 --
Alleles Carried on Transgenic Constructs ( 19 )
For All Alleles Carried on Transgenic Constructs Show
Allele of ac Class Mutagen Stocks Known lesion ac+mPa in vitro construct | minigene 0 Yes ac0.27.cvDa in vitro construct | deletion 0 Yes ac0.27X123.cvDa in vitro construct | deletion in vitro construct | site directed mutagenesis 0 Yes ac0.9.cvDa in vitro construct | deletion 0 Yes ac0.9X123.cvDa in vitro construct | deletion in vitro construct | site directed mutagenesis 0 Yes