Gene Dmel\RpLP0

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General Information

Symbol

Dmel\RpLP0

Species

D. melanogaster

Name

Ribosomal protein LP0

Annotation symbol

CG7490

Feature type

protein_coding_gene

FlyBase ID

FBgn0000100

Gene Model Status

Current

Stock availability

10 publicly available

Also Known As

RpP0, AP3, PO, P0

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

79B2-79B2

Sequence location

3L:22,068,967..22,070,587 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene Ribosomal protein LP0 is referred to in FlyBase by the symbol Dmel\RpLP0 (CG7490, FBgn0000100). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process: translation. 12 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ribosomal protein 60S; Ribosomal protein L10/acidic P0. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637546_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RpLP0. Gene sequence location is 3L:22068967..22070587.

User Contributed Data

Beta version, feedback welcome

Phenotypic Description from the Red Book (Lindsley & Zimm 1992)

Gene/Allele symbols may differ from current usage

Ape: Apurinic endonuclease

Encodes an apurinic-apyrimidinic DNA endonuclease, AP3. Biochemical studies by Spiering and Deutsch (1986, J. Biol. Chem. 261: 3222-28).

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

79B2-79B2

Limits computationally determined from genome sequence between P{lacW}l(3)j1B10^j1B10 and P{lacW}l(3)j2C4^j2C4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

79D1-79D2

(determined by in situ hybridisation)

(Spradling et al., 1999)

79D1-79D2

(determined by in situ hybridisation)

(BDGP Project Members, 1994-1999)

79C-79D

(determined by in situ hybridisation)

(Kelley et al., 1989)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\RpLP0 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.46

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

RpLP0-RA

FBtr0078481

NM_079487

1211

317

RpLP0-RB

FBtr0334113

NM_001275273

1328

317

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

RpLP0-PA

FBpp0078134

34.2

317

6.95

NP_524211

AAF51807

RpLP0-PB

FBpp0306232

34.2

317

6.95

NP_001262202

AGB94895

Additional Polypeptide Data & Comments

Reported size (kDa)

317 (aa); 34 (kD)

(Grabowski et al., 1991)

Comments

Contains CKI and CKII phosphorylation sites.

(Grabowski et al., 1991)

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Ribosomal protein L10/acidic P0 (IPR001790)

Ribosomal protein L10/L12 (IPR001813)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

P19889

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

ribosome

inferred from direct assay

(Alonso and Santaren, 2006)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		2951.675
Larval Midgut		4502.4
Larval Hindgut		4562.7
Larval Malpighian Tubules		4869.2
Larval Fat Body		8487.6
Larval Salivary Gland		7889.2
Larval Trachea		6413
Larval Carcass		4853.6
Adult Head		4712.6
Adult Eye		5523.825
Adult Brain		3008.3
Adult Thoracic-Abdominal Ganglion		3891.2
Adult Crop		6556.4
Adult Midgut		5077.5
Adult Hindgut		5280
Adult Malpighian Tubules		5919.8
Adult Fat Body		6184.7
Adult Salivary Gland		9254.5
Adult Heart		6325
Adult VirginFemale Spermatheca		6116.8
Adult InseminatedFemale Spermatheca		6418.4
Adult Ovary		3672.1
Adult Testis		1022
Adult Male Accessory Gland		9187.4
Adult Carcass		5674.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(2951.675)
Larval Midgut		(4502.4)
Larval Hindgut		(4562.7)
Larval Malpighian Tubules		(4869.2)
Larval Fat Body		(8487.6)
Larval Salivary Gland		(7889.2)
Larval Trachea		(6413)
Larval Carcass		(4853.6)
Adult Head		(4712.6)
Adult Eye		(5523.825)
Adult Brain		(3008.3)
Adult Thoracic-Abdominal Ganglion		(3891.2)
Adult Crop		(6556.4)
Adult Midgut		(5077.5)
Adult Hindgut		(5280)
Adult Malpighian Tubules		(5919.8)
Adult Fat Body		(6184.7)
Adult Salivary Gland		(9254.5)
Adult Heart		(6325)
Adult VirginFemale Spermatheca		(6116.8)
Adult InseminatedFemale Spermatheca		(6418.4)
Adult Ovary		(3672.1)
Adult Testis		(1022)
Adult Male Accessory Gland		(9187.4)
Adult Carcass		(5674.3)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(2951.675)
Larval Midgut		(4502.4)
Larval Hindgut		(4562.7)
Larval Malpighian Tubules		(4869.2)
Larval Fat Body		(8487.6)
Larval Salivary Gland		(7889.2)
Larval Trachea		(6413)
Larval Carcass		(4853.6)
Adult Head		(4712.6)
Adult Eye		(5523.825)
Adult Brain		(3008.3)
Adult Thoracic-Abdominal Ganglion		(3891.2)
Adult Crop		(6556.4)
Adult Midgut		(5077.5)
Adult Hindgut		(5280)
Adult Malpighian Tubules		(5919.8)
Adult Fat Body		(6184.7)
Adult Salivary Gland		(9254.5)
Adult Heart		(6325)
Adult VirginFemale Spermatheca		(6116.8)
Adult InseminatedFemale Spermatheca		(6418.4)
Adult Ovary		(3672.1)
Adult Testis		1022
Adult Male Accessory Gland		(9187.4)
Adult Carcass		(5674.3)
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2951.675
Larval Midgut		4502.4
Larval Hindgut		4562.7
Larval Malpighian Tubules		4869.2
Larval Fat Body		8487.6
Larval Salivary Gland		7889.2
Larval Trachea		6413
Larval Carcass		4853.6
Adult Head		4712.6
Adult Eye		5523.825
Adult Brain		3008.3
Adult Thoracic-Abdominal Ganglion		3891.2
Adult Crop		6556.4
Adult Midgut		5077.5
Adult Hindgut		5280
Adult Malpighian Tubules		5919.8
Adult Fat Body		6184.7
Adult Salivary Gland		9254.5
Adult Heart		6325
Adult VirginFemale Spermatheca		6116.8
Adult InseminatedFemale Spermatheca		6418.4
Adult Ovary		3672.1
Adult Testis		1022
Adult Male Accessory Gland		9187.4
Adult Carcass		5674.3
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		2951.675
Larval Midgut		4502.4
Larval Hindgut		4562.7
Larval Malpighian Tubules		4869.2
Larval Fat Body		8487.6
Larval Salivary Gland		7889.2
Larval Trachea		6413
Larval Carcass		4853.6
Adult Head		4712.6
Adult Eye		5523.825
Adult Brain		3008.3
Adult Thoracic-Abdominal Ganglion		3891.2
Adult Crop		6556.4
Adult Midgut		5077.5
Adult Hindgut		5280
Adult Malpighian Tubules		5919.8
Adult Fat Body		6184.7
Adult Salivary Gland		9254.5
Adult Heart		6325
Adult VirginFemale Spermatheca		6116.8
Adult InseminatedFemale Spermatheca		6418.4
Adult Ovary		3672.1
Adult Testis		1022
Adult Male Accessory Gland		9187.4
Adult Carcass		5674.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(2951.675)
Larval Midgut		(4502.4)
Larval Hindgut		(4562.7)
Larval Malpighian Tubules		(4869.2)
Larval Fat Body		(8487.6)
Larval Salivary Gland		(7889.2)
Larval Trachea		(6413)
Larval Carcass		(4853.6)
Adult Head		(4712.6)
Adult Eye		(5523.825)
Adult Brain		(3008.3)
Adult Thoracic-Abdominal Ganglion		(3891.2)
Adult Crop		(6556.4)
Adult Midgut		(5077.5)
Adult Hindgut		(5280)
Adult Malpighian Tubules		(5919.8)
Adult Fat Body		(6184.7)
Adult Salivary Gland		(9254.5)
Adult Heart		(6325)
Adult VirginFemale Spermatheca		(6116.8)
Adult InseminatedFemale Spermatheca		(6418.4)
Adult Ovary		(3672.1)
Adult Testis		(1022)
Adult Male Accessory Gland		(9187.4)
Adult Carcass		(5674.3)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(2951.675)
Larval Midgut		(4502.4)
Larval Hindgut		(4562.7)
Larval Malpighian Tubules		(4869.2)
Larval Fat Body		(8487.6)
Larval Salivary Gland		(7889.2)
Larval Trachea		(6413)
Larval Carcass		(4853.6)
Adult Head		(4712.6)
Adult Eye		(5523.825)
Adult Brain		(3008.3)
Adult Thoracic-Abdominal Ganglion		(3891.2)
Adult Crop		(6556.4)
Adult Midgut		(5077.5)
Adult Hindgut		(5280)
Adult Malpighian Tubules		(5919.8)
Adult Fat Body		(6184.7)
Adult Salivary Gland		(9254.5)
Adult Heart		(6325)
Adult VirginFemale Spermatheca		(6116.8)
Adult InseminatedFemale Spermatheca		(6418.4)
Adult Ovary		(3672.1)
Adult Testis		1022
Adult Male Accessory Gland		(9187.4)
Adult Carcass		(5674.3)
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2951.675
Larval Midgut		4502.4
Larval Hindgut		4562.7
Larval Malpighian Tubules		4869.2
Larval Fat Body		8487.6
Larval Salivary Gland		7889.2
Larval Trachea		6413
Larval Carcass		4853.6
Adult Head		4712.6
Adult Eye		5523.825
Adult Brain		3008.3
Adult Thoracic-Abdominal Ganglion		3891.2
Adult Crop		6556.4
Adult Midgut		5077.5
Adult Hindgut		5280
Adult Malpighian Tubules		5919.8
Adult Fat Body		6184.7
Adult Salivary Gland		9254.5
Adult Heart		6325
Adult VirginFemale Spermatheca		6116.8
Adult InseminatedFemale Spermatheca		6418.4
Adult Ovary		3672.1
Adult Testis		1022
Adult Male Accessory Gland		9187.4
Adult Carcass		5674.3
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	4712.6
NA	Eye	5523.825
NA	Brain	3008.3
2951.675	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	3891.2
NA	Crop	6556.4
4502.4	Midgut	5077.5
4562.7	Hindgut	5280
4869.2	Malpighian Tubules	5919.8
8487.6	Fat Body	6184.7
7889.2	Salivary Gland	9254.5
NA	Heart	6325
6413	Trachea	NA
NA	VirginFemale Spermatheca	6116.8
NA	InseminatedFemale Spermatheca	6418.4
NA	Ovary	3672.1
NA	Testis	1022
NA	Male Accessory Gland	9187.4
4853.6	Carcass	5674.3

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1135
central nervous system, larvae L3		574
central nervous system, pupae P8		236
head, virgin 1-day female		326
head, virgin 4-day female		493
head, virgin 20-day female		871
head, mated 1-day female		287
head, mated 4-day female		454
head, mated 20-day female		675
head, mated 1-day male		293
head, mated 4-day male		330
head, mated 20-day male		529
salivary gland, larvae L3 wandering		307
salivary gland, white prepupae		614
digestive system, larvae L3 wandering		461
digestive system, 1-day adult		552
digestive system, 4-day adult		477
digestive system, 20-day adult		567
fat body, larvae L3 wandering		377
fat body, white prepupae		253
fat body, pupae P8		438
carcass, larvae L3 wandering		750
carcass, 1-day adult		307
carcass, 4-day adult		380
carcass, 20-day adult		619
ovary, virgin 4-day female		406
ovary, mated 4-day female		379
testis, mated 4-day male		306
accessory gland, mated 4-day male		718
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(1135)
central nervous system, larvae L3		(574)
central nervous system, pupae P8		(236)
head, virgin 1-day female		(326)
head, virgin 4-day female		(493)
head, virgin 20-day female		(871)
head, mated 1-day female		(287)
head, mated 4-day female		(454)
head, mated 20-day female		(675)
head, mated 1-day male		(293)
head, mated 4-day male		(330)
head, mated 20-day male		(529)
salivary gland, larvae L3 wandering		(307)
salivary gland, white prepupae		(614)
digestive system, larvae L3 wandering		(461)
digestive system, 1-day adult		(552)
digestive system, 4-day adult		(477)
digestive system, 20-day adult		(567)
fat body, larvae L3 wandering		(377)
fat body, white prepupae		(253)
fat body, pupae P8		(438)
carcass, larvae L3 wandering		(750)
carcass, 1-day adult		(307)
carcass, 4-day adult		(380)
carcass, 20-day adult		(619)
ovary, virgin 4-day female		(406)
ovary, mated 4-day female		(379)
testis, mated 4-day male		(306)
accessory gland, mated 4-day male		(718)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(1135)
central nervous system, larvae L3		(574)
central nervous system, pupae P8		(236)
head, virgin 1-day female		(326)
head, virgin 4-day female		(493)
head, virgin 20-day female		(871)
head, mated 1-day female		(287)
head, mated 4-day female		(454)
head, mated 20-day female		(675)
head, mated 1-day male		(293)
head, mated 4-day male		(330)
head, mated 20-day male		(529)
salivary gland, larvae L3 wandering		(307)
salivary gland, white prepupae		(614)
digestive system, larvae L3 wandering		(461)
digestive system, 1-day adult		(552)
digestive system, 4-day adult		(477)
digestive system, 20-day adult		(567)
fat body, larvae L3 wandering		(377)
fat body, white prepupae		(253)
fat body, pupae P8		(438)
carcass, larvae L3 wandering		(750)
carcass, 1-day adult		(307)
carcass, 4-day adult		(380)
carcass, 20-day adult		(619)
ovary, virgin 4-day female		(406)
ovary, mated 4-day female		(379)
testis, mated 4-day male		(306)
accessory gland, mated 4-day male		(718)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1135
central nervous system, larvae L3		574
central nervous system, pupae P8		236
head, virgin 1-day female		326
head, virgin 4-day female		493
head, virgin 20-day female		871
head, mated 1-day female		287
head, mated 4-day female		454
head, mated 20-day female		675
head, mated 1-day male		293
head, mated 4-day male		330
head, mated 20-day male		529
salivary gland, larvae L3 wandering		307
salivary gland, white prepupae		614
digestive system, larvae L3 wandering		461
digestive system, 1-day adult		552
digestive system, 4-day adult		477
digestive system, 20-day adult		567
fat body, larvae L3 wandering		377
fat body, white prepupae		253
fat body, pupae P8		438
carcass, larvae L3 wandering		750
carcass, 1-day adult		307
carcass, 4-day adult		380
carcass, 20-day adult		619
ovary, virgin 4-day female		406
ovary, mated 4-day female		379
testis, mated 4-day male		306
accessory gland, mated 4-day male		718
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1135
central nervous system, larvae L3		574
central nervous system, pupae P8		236
head, virgin 1-day female		326
head, virgin 4-day female		493
head, virgin 20-day female		871
head, mated 1-day female		287
head, mated 4-day female		454
head, mated 20-day female		675
head, mated 1-day male		293
head, mated 4-day male		330
head, mated 20-day male		529
salivary gland, larvae L3 wandering		307
salivary gland, white prepupae		614
digestive system, larvae L3 wandering		461
digestive system, 1-day adult		552
digestive system, 4-day adult		477
digestive system, 20-day adult		567
fat body, larvae L3 wandering		377
fat body, white prepupae		253
fat body, pupae P8		438
carcass, larvae L3 wandering		750
carcass, 1-day adult		307
carcass, 4-day adult		380
carcass, 20-day adult		619
ovary, virgin 4-day female		406
ovary, mated 4-day female		379
testis, mated 4-day male		306
accessory gland, mated 4-day male		718
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(1135)
central nervous system, larvae L3		(574)
central nervous system, pupae P8		(236)
head, virgin 1-day female		(326)
head, virgin 4-day female		(493)
head, virgin 20-day female		(871)
head, mated 1-day female		(287)
head, mated 4-day female		(454)
head, mated 20-day female		(675)
head, mated 1-day male		(293)
head, mated 4-day male		(330)
head, mated 20-day male		(529)
salivary gland, larvae L3 wandering		(307)
salivary gland, white prepupae		(614)
digestive system, larvae L3 wandering		(461)
digestive system, 1-day adult		(552)
digestive system, 4-day adult		(477)
digestive system, 20-day adult		(567)
fat body, larvae L3 wandering		(377)
fat body, white prepupae		(253)
fat body, pupae P8		(438)
carcass, larvae L3 wandering		(750)
carcass, 1-day adult		(307)
carcass, 4-day adult		(380)
carcass, 20-day adult		(619)
ovary, virgin 4-day female		(406)
ovary, mated 4-day female		(379)
testis, mated 4-day male		(306)
accessory gland, mated 4-day male		(718)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(1135)
central nervous system, larvae L3		(574)
central nervous system, pupae P8		(236)
head, virgin 1-day female		(326)
head, virgin 4-day female		(493)
head, virgin 20-day female		(871)
head, mated 1-day female		(287)
head, mated 4-day female		(454)
head, mated 20-day female		(675)
head, mated 1-day male		(293)
head, mated 4-day male		(330)
head, mated 20-day male		(529)
salivary gland, larvae L3 wandering		(307)
salivary gland, white prepupae		(614)
digestive system, larvae L3 wandering		(461)
digestive system, 1-day adult		(552)
digestive system, 4-day adult		(477)
digestive system, 20-day adult		(567)
fat body, larvae L3 wandering		(377)
fat body, white prepupae		(253)
fat body, pupae P8		(438)
carcass, larvae L3 wandering		(750)
carcass, 1-day adult		(307)
carcass, 4-day adult		(380)
carcass, 20-day adult		(619)
ovary, virgin 4-day female		(406)
ovary, mated 4-day female		(379)
testis, mated 4-day male		(306)
accessory gland, mated 4-day male		(718)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1135
central nervous system, larvae L3		574
central nervous system, pupae P8		236
head, virgin 1-day female		326
head, virgin 4-day female		493
head, virgin 20-day female		871
head, mated 1-day female		287
head, mated 4-day female		454
head, mated 20-day female		675
head, mated 1-day male		293
head, mated 4-day male		330
head, mated 20-day male		529
salivary gland, larvae L3 wandering		307
salivary gland, white prepupae		614
digestive system, larvae L3 wandering		461
digestive system, 1-day adult		552
digestive system, 4-day adult		477
digestive system, 20-day adult		567
fat body, larvae L3 wandering		377
fat body, white prepupae		253
fat body, pupae P8		438
carcass, larvae L3 wandering		750
carcass, 1-day adult		307
carcass, 4-day adult		380
carcass, 20-day adult		619
ovary, virgin 4-day female		406
ovary, mated 4-day female		379
testis, mated 4-day male		306
accessory gland, mated 4-day male		718
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1160
embryo 02-04hr		1691
embryo 04-06hr		1393
embryo 06-08hr		1287
embryo 08-10hr		1416
embryo 10-12hr		2012
embryo 12-14hr		1110
embryo 14-16hr		1540
embryo 16-18hr		1337
embryo 18-20hr		1570
embryo 20-22hr		1621
embryo 22-24hr		1367
larva L1		2252
larva L2		1986
larva L3 12hr old		1680
larva L3 puffstage 1-2		1237
larva L3 puffstage 3-6		1153
larva L3 puffstage 7-9		1108
white prepupae new		968
white prepupae 12hr		758
white prepupae 24hr		818
pupae 2d postWPP		745
pupae 3d postWPP		647
pupae 4d postWPP		701
adult male 01day		589
adult male 05day		653
adult male 30day		711
adult female 01day		1565
adult female 05day		1482
adult female 30day		1590
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(1160)
embryo 02-04hr		(1691)
embryo 04-06hr		(1393)
embryo 06-08hr		(1287)
embryo 08-10hr		(1416)
embryo 10-12hr		(2012)
embryo 12-14hr		(1110)
embryo 14-16hr		(1540)
embryo 16-18hr		(1337)
embryo 18-20hr		(1570)
embryo 20-22hr		(1621)
embryo 22-24hr		(1367)
larva L1		(2252)
larva L2		(1986)
larva L3 12hr old		(1680)
larva L3 puffstage 1-2		(1237)
larva L3 puffstage 3-6		(1153)
larva L3 puffstage 7-9		(1108)
white prepupae new		(968)
white prepupae 12hr		(758)
white prepupae 24hr		(818)
pupae 2d postWPP		(745)
pupae 3d postWPP		(647)
pupae 4d postWPP		(701)
adult male 01day		(589)
adult male 05day		(653)
adult male 30day		(711)
adult female 01day		(1565)
adult female 05day		(1482)
adult female 30day		(1590)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(1160)
embryo 02-04hr		(1691)
embryo 04-06hr		(1393)
embryo 06-08hr		(1287)
embryo 08-10hr		(1416)
embryo 10-12hr		(2012)
embryo 12-14hr		(1110)
embryo 14-16hr		(1540)
embryo 16-18hr		(1337)
embryo 18-20hr		(1570)
embryo 20-22hr		(1621)
embryo 22-24hr		(1367)
larva L1		(2252)
larva L2		(1986)
larva L3 12hr old		(1680)
larva L3 puffstage 1-2		(1237)
larva L3 puffstage 3-6		(1153)
larva L3 puffstage 7-9		(1108)
white prepupae new		(968)
white prepupae 12hr		(758)
white prepupae 24hr		(818)
pupae 2d postWPP		(745)
pupae 3d postWPP		(647)
pupae 4d postWPP		(701)
adult male 01day		(589)
adult male 05day		(653)
adult male 30day		(711)
adult female 01day		(1565)
adult female 05day		(1482)
adult female 30day		(1590)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1160
embryo 02-04hr		1691
embryo 04-06hr		1393
embryo 06-08hr		1287
embryo 08-10hr		1416
embryo 10-12hr		2012
embryo 12-14hr		1110
embryo 14-16hr		1540
embryo 16-18hr		1337
embryo 18-20hr		1570
embryo 20-22hr		1621
embryo 22-24hr		1367
larva L1		2252
larva L2		1986
larva L3 12hr old		1680
larva L3 puffstage 1-2		1237
larva L3 puffstage 3-6		1153
larva L3 puffstage 7-9		1108
white prepupae new		968
white prepupae 12hr		758
white prepupae 24hr		818
pupae 2d postWPP		745
pupae 3d postWPP		647
pupae 4d postWPP		701
adult male 01day		589
adult male 05day		653
adult male 30day		711
adult female 01day		1565
adult female 05day		1482
adult female 30day		1590
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1160
embryo 02-04hr		1691
embryo 04-06hr		1393
embryo 06-08hr		1287
embryo 08-10hr		1416
embryo 10-12hr		2012
embryo 12-14hr		1110
embryo 14-16hr		1540
embryo 16-18hr		1337
embryo 18-20hr		1570
embryo 20-22hr		1621
embryo 22-24hr		1367
larva L1		2252
larva L2		1986
larva L3 12hr old		1680
larva L3 puffstage 1-2		1237
larva L3 puffstage 3-6		1153
larva L3 puffstage 7-9		1108
white prepupae new		968
white prepupae 12hr		758
white prepupae 24hr		818
pupae 2d postWPP		745
pupae 3d postWPP		647
pupae 4d postWPP		701
adult male 01day		589
adult male 05day		653
adult male 30day		711
adult female 01day		1565
adult female 05day		1482
adult female 30day		1590
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(1160)
embryo 02-04hr		(1691)
embryo 04-06hr		(1393)
embryo 06-08hr		(1287)
embryo 08-10hr		(1416)
embryo 10-12hr		(2012)
embryo 12-14hr		(1110)
embryo 14-16hr		(1540)
embryo 16-18hr		(1337)
embryo 18-20hr		(1570)
embryo 20-22hr		(1621)
embryo 22-24hr		(1367)
larva L1		(2252)
larva L2		(1986)
larva L3 12hr old		(1680)
larva L3 puffstage 1-2		(1237)
larva L3 puffstage 3-6		(1153)
larva L3 puffstage 7-9		(1108)
white prepupae new		(968)
white prepupae 12hr		(758)
white prepupae 24hr		(818)
pupae 2d postWPP		(745)
pupae 3d postWPP		(647)
pupae 4d postWPP		(701)
adult male 01day		(589)
adult male 05day		(653)
adult male 30day		(711)
adult female 01day		(1565)
adult female 05day		(1482)
adult female 30day		(1590)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(1160)
embryo 02-04hr		(1691)
embryo 04-06hr		(1393)
embryo 06-08hr		(1287)
embryo 08-10hr		(1416)
embryo 10-12hr		(2012)
embryo 12-14hr		(1110)
embryo 14-16hr		(1540)
embryo 16-18hr		(1337)
embryo 18-20hr		(1570)
embryo 20-22hr		(1621)
embryo 22-24hr		(1367)
larva L1		(2252)
larva L2		(1986)
larva L3 12hr old		(1680)
larva L3 puffstage 1-2		(1237)
larva L3 puffstage 3-6		(1153)
larva L3 puffstage 7-9		(1108)
white prepupae new		(968)
white prepupae 12hr		(758)
white prepupae 24hr		(818)
pupae 2d postWPP		(745)
pupae 3d postWPP		(647)
pupae 4d postWPP		(701)
adult male 01day		(589)
adult male 05day		(653)
adult male 30day		(711)
adult female 01day		(1565)
adult female 05day		(1482)
adult female 30day		(1590)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1160
embryo 02-04hr		1691
embryo 04-06hr		1393
embryo 06-08hr		1287
embryo 08-10hr		1416
embryo 10-12hr		2012
embryo 12-14hr		1110
embryo 14-16hr		1540
embryo 16-18hr		1337
embryo 18-20hr		1570
embryo 20-22hr		1621
embryo 22-24hr		1367
larva L1		2252
larva L2		1986
larva L3 12hr old		1680
larva L3 puffstage 1-2		1237
larva L3 puffstage 3-6		1153
larva L3 puffstage 7-9		1108
white prepupae new		968
white prepupae 12hr		758
white prepupae 24hr		818
pupae 2d postWPP		745
pupae 3d postWPP		647
pupae 4d postWPP		701
adult male 01day		589
adult male 05day		653
adult male 30day		711
adult female 01day		1565
adult female 05day		1482
adult female 30day		1590
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		1234
Schneider line 2 Sg4		2060
embryonic 1182-4H		998
embryonic GM2		564
embryonic Kc167		991
embryonic S1		1060
embryonic S3		1144
leg disc CME L1		1342
wing disc CME-W2		1033
wing disc ML-DmD8		892
wing disc ML-DmD9		1086
wing disc ML-DmD16-c3		973
wing disc ML-DmD21		2992
wing disc ML-DmD32		998
haltere disc ML-DmD17-c3		794
eye-antennal disc ML-DmD11		1591
antennal disc ML-DmD20-c5		1917
mixed discs ML-DmD4-c1		1123
CNS ML-DmBG1-c1		945
CNS ML-DmBG2-c2		938
tumorous blood cells mbn2		614
ovary fGS/OSS		432
ovary OSC		277
ovary OSS		157
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(1234)
Schneider line 2 Sg4		(2060)
embryonic 1182-4H		(998)
embryonic GM2		(564)
embryonic Kc167		(991)
embryonic S1		(1060)
embryonic S3		(1144)
leg disc CME L1		(1342)
wing disc CME-W2		(1033)
wing disc ML-DmD8		(892)
wing disc ML-DmD9		(1086)
wing disc ML-DmD16-c3		(973)
wing disc ML-DmD21		(2992)
wing disc ML-DmD32		(998)
haltere disc ML-DmD17-c3		(794)
eye-antennal disc ML-DmD11		(1591)
antennal disc ML-DmD20-c5		(1917)
mixed discs ML-DmD4-c1		(1123)
CNS ML-DmBG1-c1		(945)
CNS ML-DmBG2-c2		(938)
tumorous blood cells mbn2		(614)
ovary fGS/OSS		(432)
ovary OSC		(277)
ovary OSS		(157)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(1234)
Schneider line 2 Sg4		(2060)
embryonic 1182-4H		(998)
embryonic GM2		(564)
embryonic Kc167		(991)
embryonic S1		(1060)
embryonic S3		(1144)
leg disc CME L1		(1342)
wing disc CME-W2		(1033)
wing disc ML-DmD8		(892)
wing disc ML-DmD9		(1086)
wing disc ML-DmD16-c3		(973)
wing disc ML-DmD21		(2992)
wing disc ML-DmD32		(998)
haltere disc ML-DmD17-c3		(794)
eye-antennal disc ML-DmD11		(1591)
antennal disc ML-DmD20-c5		(1917)
mixed discs ML-DmD4-c1		(1123)
CNS ML-DmBG1-c1		(945)
CNS ML-DmBG2-c2		(938)
tumorous blood cells mbn2		(614)
ovary fGS/OSS		(432)
ovary OSC		(277)
ovary OSS		(157)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		1234
Schneider line 2 Sg4		2060
embryonic 1182-4H		998
embryonic GM2		564
embryonic Kc167		991
embryonic S1		1060
embryonic S3		1144
leg disc CME L1		1342
wing disc CME-W2		1033
wing disc ML-DmD8		892
wing disc ML-DmD9		1086
wing disc ML-DmD16-c3		973
wing disc ML-DmD21		2992
wing disc ML-DmD32		998
haltere disc ML-DmD17-c3		794
eye-antennal disc ML-DmD11		1591
antennal disc ML-DmD20-c5		1917
mixed discs ML-DmD4-c1		1123
CNS ML-DmBG1-c1		945
CNS ML-DmBG2-c2		938
tumorous blood cells mbn2		614
ovary fGS/OSS		432
ovary OSC		277
ovary OSS		157
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		1234
Schneider line 2 Sg4		2060
embryonic 1182-4H		998
embryonic GM2		564
embryonic Kc167		991
embryonic S1		1060
embryonic S3		1144
leg disc CME L1		1342
wing disc CME-W2		1033
wing disc ML-DmD8		892
wing disc ML-DmD9		1086
wing disc ML-DmD16-c3		973
wing disc ML-DmD21		2992
wing disc ML-DmD32		998
haltere disc ML-DmD17-c3		794
eye-antennal disc ML-DmD11		1591
antennal disc ML-DmD20-c5		1917
mixed discs ML-DmD4-c1		1123
CNS ML-DmBG1-c1		945
CNS ML-DmBG2-c2		938
tumorous blood cells mbn2		614
ovary fGS/OSS		432
ovary OSC		277
ovary OSS		157
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(1234)
Schneider line 2 Sg4		(2060)
embryonic 1182-4H		(998)
embryonic GM2		(564)
embryonic Kc167		(991)
embryonic S1		(1060)
embryonic S3		(1144)
leg disc CME L1		(1342)
wing disc CME-W2		(1033)
wing disc ML-DmD8		(892)
wing disc ML-DmD9		(1086)
wing disc ML-DmD16-c3		(973)
wing disc ML-DmD21		(2992)
wing disc ML-DmD32		(998)
haltere disc ML-DmD17-c3		(794)
eye-antennal disc ML-DmD11		(1591)
antennal disc ML-DmD20-c5		(1917)
mixed discs ML-DmD4-c1		(1123)
CNS ML-DmBG1-c1		(945)
CNS ML-DmBG2-c2		(938)
tumorous blood cells mbn2		(614)
ovary fGS/OSS		(432)
ovary OSC		(277)
ovary OSS		(157)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(1234)
Schneider line 2 Sg4		(2060)
embryonic 1182-4H		(998)
embryonic GM2		(564)
embryonic Kc167		(991)
embryonic S1		(1060)
embryonic S3		(1144)
leg disc CME L1		(1342)
wing disc CME-W2		(1033)
wing disc ML-DmD8		(892)
wing disc ML-DmD9		(1086)
wing disc ML-DmD16-c3		(973)
wing disc ML-DmD21		(2992)
wing disc ML-DmD32		(998)
haltere disc ML-DmD17-c3		(794)
eye-antennal disc ML-DmD11		(1591)
antennal disc ML-DmD20-c5		(1917)
mixed discs ML-DmD4-c1		(1123)
CNS ML-DmBG1-c1		(945)
CNS ML-DmBG2-c2		(938)
tumorous blood cells mbn2		(614)
ovary fGS/OSS		(432)
ovary OSC		(277)
ovary OSS		(157)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		1234
Schneider line 2 Sg4		2060
embryonic 1182-4H		998
embryonic GM2		564
embryonic Kc167		991
embryonic S1		1060
embryonic S3		1144
leg disc CME L1		1342
wing disc CME-W2		1033
wing disc ML-DmD8		892
wing disc ML-DmD9		1086
wing disc ML-DmD16-c3		973
wing disc ML-DmD21		2992
wing disc ML-DmD32		998
haltere disc ML-DmD17-c3		794
eye-antennal disc ML-DmD11		1591
antennal disc ML-DmD20-c5		1917
mixed discs ML-DmD4-c1		1123
CNS ML-DmBG1-c1		945
CNS ML-DmBG2-c2		938
tumorous blood cells mbn2		614
ovary fGS/OSS		432
ovary OSC		277
ovary OSS		157
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		368
cold shock, 4-day adult		280
heat shock, 4-day adult		824
Cadmium 50 mM 6 hrs, larvae L3		1037
Cadmium 50 mM 12 hrs, larvae L3		754
Cadmium 50 mM 48 hrs, 4-day adult		587
Cadmium 100 mM 48 hrs, 4-day adult		321
Copper 0.5 mM 12 hrs, larvae L3		428
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		354
Zinc 4.5 mM 48 hrs, 4-day adult		220
Ethanol 2.5% 3 hrs, larvae L3		660
Ethanol 5% 3 hrs, larvae L3		883
Ethanol 10% 3 hrs, larvae L3		884
Caffeine 1.5 mg/ml 4 hrs, larvae L3		811
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		387
Caffeine 25 mg/ml 48 hrs, 4-day adult		255
Paraquat 5 mM 48 hrs, 4-day adult		520
Paraquat 10 mM 48 hrs, 4-day adult		752
Rotenone 2 μg 12 hrs, larvae L3		1045
Rotenone 8 μg 12 hrs, larvae L3		1261
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(368)
cold shock, 4-day adult		(280)
heat shock, 4-day adult		(824)
Cadmium 50 mM 6 hrs, larvae L3		(1037)
Cadmium 50 mM 12 hrs, larvae L3		(754)
Cadmium 50 mM 48 hrs, 4-day adult		(587)
Cadmium 100 mM 48 hrs, 4-day adult		(321)
Copper 0.5 mM 12 hrs, larvae L3		(428)
Copper 15 mM 48 hrs, 4-day adult		(100)
Zinc 5 mM 12 hrs, larvae L3		(354)
Zinc 4.5 mM 48 hrs, 4-day adult		(220)
Ethanol 2.5% 3 hrs, larvae L3		(660)
Ethanol 5% 3 hrs, larvae L3		(883)
Ethanol 10% 3 hrs, larvae L3		(884)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(811)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(387)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(255)
Paraquat 5 mM 48 hrs, 4-day adult		(520)
Paraquat 10 mM 48 hrs, 4-day adult		(752)
Rotenone 2 μg 12 hrs, larvae L3		(1045)
Rotenone 8 μg 12 hrs, larvae L3		(1261)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		(368)
cold shock, 4-day adult		(280)
heat shock, 4-day adult		(824)
Cadmium 50 mM 6 hrs, larvae L3		(1037)
Cadmium 50 mM 12 hrs, larvae L3		(754)
Cadmium 50 mM 48 hrs, 4-day adult		(587)
Cadmium 100 mM 48 hrs, 4-day adult		(321)
Copper 0.5 mM 12 hrs, larvae L3		(428)
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		(354)
Zinc 4.5 mM 48 hrs, 4-day adult		(220)
Ethanol 2.5% 3 hrs, larvae L3		(660)
Ethanol 5% 3 hrs, larvae L3		(883)
Ethanol 10% 3 hrs, larvae L3		(884)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(811)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(387)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(255)
Paraquat 5 mM 48 hrs, 4-day adult		(520)
Paraquat 10 mM 48 hrs, 4-day adult		(752)
Rotenone 2 μg 12 hrs, larvae L3		(1045)
Rotenone 8 μg 12 hrs, larvae L3		(1261)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		368
cold shock, 4-day adult		280
heat shock, 4-day adult		824
Cadmium 50 mM 6 hrs, larvae L3		1037
Cadmium 50 mM 12 hrs, larvae L3		754
Cadmium 50 mM 48 hrs, 4-day adult		587
Cadmium 100 mM 48 hrs, 4-day adult		321
Copper 0.5 mM 12 hrs, larvae L3		428
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		354
Zinc 4.5 mM 48 hrs, 4-day adult		220
Ethanol 2.5% 3 hrs, larvae L3		660
Ethanol 5% 3 hrs, larvae L3		883
Ethanol 10% 3 hrs, larvae L3		884
Caffeine 1.5 mg/ml 4 hrs, larvae L3		811
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		387
Caffeine 25 mg/ml 48 hrs, 4-day adult		255
Paraquat 5 mM 48 hrs, 4-day adult		520
Paraquat 10 mM 48 hrs, 4-day adult		752
Rotenone 2 μg 12 hrs, larvae L3		1045
Rotenone 8 μg 12 hrs, larvae L3		1261
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		368
cold shock, 4-day adult		280
heat shock, 4-day adult		824
Cadmium 50 mM 6 hrs, larvae L3		1037
Cadmium 50 mM 12 hrs, larvae L3		754
Cadmium 50 mM 48 hrs, 4-day adult		587
Cadmium 100 mM 48 hrs, 4-day adult		321
Copper 0.5 mM 12 hrs, larvae L3		428
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		354
Zinc 4.5 mM 48 hrs, 4-day adult		220
Ethanol 2.5% 3 hrs, larvae L3		660
Ethanol 5% 3 hrs, larvae L3		883
Ethanol 10% 3 hrs, larvae L3		884
Caffeine 1.5 mg/ml 4 hrs, larvae L3		811
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		387
Caffeine 25 mg/ml 48 hrs, 4-day adult		255
Paraquat 5 mM 48 hrs, 4-day adult		520
Paraquat 10 mM 48 hrs, 4-day adult		752
Rotenone 2 μg 12 hrs, larvae L3		1045
Rotenone 8 μg 12 hrs, larvae L3		1261
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(368)
cold shock, 4-day adult		(280)
heat shock, 4-day adult		(824)
Cadmium 50 mM 6 hrs, larvae L3		(1037)
Cadmium 50 mM 12 hrs, larvae L3		(754)
Cadmium 50 mM 48 hrs, 4-day adult		(587)
Cadmium 100 mM 48 hrs, 4-day adult		(321)
Copper 0.5 mM 12 hrs, larvae L3		(428)
Copper 15 mM 48 hrs, 4-day adult		(100)
Zinc 5 mM 12 hrs, larvae L3		(354)
Zinc 4.5 mM 48 hrs, 4-day adult		(220)
Ethanol 2.5% 3 hrs, larvae L3		(660)
Ethanol 5% 3 hrs, larvae L3		(883)
Ethanol 10% 3 hrs, larvae L3		(884)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(811)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(387)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(255)
Paraquat 5 mM 48 hrs, 4-day adult		(520)
Paraquat 10 mM 48 hrs, 4-day adult		(752)
Rotenone 2 μg 12 hrs, larvae L3		(1045)
Rotenone 8 μg 12 hrs, larvae L3		(1261)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		(368)
cold shock, 4-day adult		(280)
heat shock, 4-day adult		(824)
Cadmium 50 mM 6 hrs, larvae L3		(1037)
Cadmium 50 mM 12 hrs, larvae L3		(754)
Cadmium 50 mM 48 hrs, 4-day adult		(587)
Cadmium 100 mM 48 hrs, 4-day adult		(321)
Copper 0.5 mM 12 hrs, larvae L3		(428)
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		(354)
Zinc 4.5 mM 48 hrs, 4-day adult		(220)
Ethanol 2.5% 3 hrs, larvae L3		(660)
Ethanol 5% 3 hrs, larvae L3		(883)
Ethanol 10% 3 hrs, larvae L3		(884)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(811)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(387)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(255)
Paraquat 5 mM 48 hrs, 4-day adult		(520)
Paraquat 10 mM 48 hrs, 4-day adult		(752)
Rotenone 2 μg 12 hrs, larvae L3		(1045)
Rotenone 8 μg 12 hrs, larvae L3		(1261)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		368
cold shock, 4-day adult		280
heat shock, 4-day adult		824
Cadmium 50 mM 6 hrs, larvae L3		1037
Cadmium 50 mM 12 hrs, larvae L3		754
Cadmium 50 mM 48 hrs, 4-day adult		587
Cadmium 100 mM 48 hrs, 4-day adult		321
Copper 0.5 mM 12 hrs, larvae L3		428
Copper 15 mM 48 hrs, 4-day adult		100
Zinc 5 mM 12 hrs, larvae L3		354
Zinc 4.5 mM 48 hrs, 4-day adult		220
Ethanol 2.5% 3 hrs, larvae L3		660
Ethanol 5% 3 hrs, larvae L3		883
Ethanol 10% 3 hrs, larvae L3		884
Caffeine 1.5 mg/ml 4 hrs, larvae L3		811
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		387
Caffeine 25 mg/ml 48 hrs, 4-day adult		255
Paraquat 5 mM 48 hrs, 4-day adult		520
Paraquat 10 mM 48 hrs, 4-day adult		752
Rotenone 2 μg 12 hrs, larvae L3		1045
Rotenone 8 μg 12 hrs, larvae L3		1261
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

RE74511

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0000100

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG7490-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

RpLP0^GD13189

lethal | recessive

RpLP0⁰¹⁵⁴⁴

Other Phenotypes

Allele

non-suppressor of variegation, with In(1)w^m4h

RpLP0³⁰⁶

suppressor of variegation | dominant, with In(1)w^m4h

RpLP0⁰¹⁵⁴⁴

wild-type

RpLP0^rev

Phenotype manifest in

Allele

Classical Alleles ( 10 )

For All Classical Alleles Show

Allele of RpLP0	Class	Mutagen	Stocks	Known lesion
RpLP0^NP2385			2	--
RpLP0⁰¹⁵⁴⁴	hypermorphic allele - genetic evidence, gain of function allele	P-element activity	1	Yes
RpLP0^c05892			1	--
RpLP0^d09567		P-element activity	1	--
RpLP0^DP00460			1	--
RpLP0^UM-8046-3			1	--
RpLP0³⁰⁶	loss of function allele	Delta2-3	0	Yes
RpLP0³⁶		Delta2-3	0	Yes
RpLP0⁸		Delta2-3	0	Yes
RpLP0^rev	wild-type allele	Delta2-3	0	Yes

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of RpLP0	Class	Mutagen	Stocks	Known lesion
RpLP0^GD13189		in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
RpLP0^JF01335		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Not disrupted in

Df(3L)Pc