RpP0, AP3, PO, Ape, LP0
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
317 (aa); 34 (kD)
Contains CKI and CKII phosphorylation sites.
P0 forms a pentameric complex by interaction with dimers of P1 and P2.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RpLP0 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\RpLP0 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: RpP0 l(3)01544
Not a Minute gene.
Deletions removing RpLP0 but no other cytoplasmic ribosomal protein-encoding genes do not show Minute phenotypes.
RpLP0 acts on abasic DNA, a lesion known to block DNA replication and case mutations in E.coli. RpLP0 also contains vigorous DNase activity for both single- and double-stranded DNA. RpLP0 can be found in the nucleus tightly associated with the nuclear matrix.
Isolated from a cDNA expression library using antiserum directed against human enzyme known to cross react with the Drosophila enzyme (FBrf0044682).
Encodes an apurinic-apyrimidinic DNA endonuclease, AP3.