Gene model reviewed during 5.45
Gene model reviewed during 5.56
1 (northern blot)
183 (aa); 20 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Aprt using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Aprt in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Comparison of CpG distribution in the coding region of 121 genes from six species supports the mCpG mutational hotspot explanation of CpG suppression in methylated species at position II-III and III-I.
In Aprt and Dpse\Aprt the use of alternate 5' splice sites to process an intron in pre-mRNA leads to simultaneous production of RNAs encoding nonfunctional proteins in addition to functional Aprt or Dpse\Aprt, respectively.
The structural gene for adenine phosphoribosyltransferase.
Mutant flies are resistant to the toxic effects of dietary purine.