FB2020_01, released Feb 12, 2020

Gene: Dmel\baz

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General Information
Symbol
Dmel\baz
Species
D. melanogaster
Name
bazooka
Annotation Symbol
CG5055
Feature Type
protein_coding_gene
FlyBase ID
FBgn0000163
Gene Model Status
Current
Stock Availability
28 publicly available
Gene Snapshot
bazooka (baz) encodes a scaffold protein that forms a complex with the products of par-6 and aPKC and with other cortical, cytoskeletal and regulatory proteins. It functions in cell polarization pathways in epithelial, neuronal and other cell types. [Date last reviewed: 2019-03-07]
Other Summaries
Also Known As

Par-3, Par3, Bazooka/Par3, D-Par3, l(1)G0484

Key Links
Genomic Location
Cytogenetic map
15F1-15F1
Sequence location
X:17,160,006..17,200,728 [+]
Recombination map

1-57

RefSeq locus
NC_004354 REGION:17160006..17200728
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
phosphatidic acid binding; phosphatidylinositol binding; protein binding
Predictions / Assertions
phosphatidylinositol binding
Summaries
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
baz: bazooka
Homozygous lethal, large dorsal and ventral hole in embryo. Homozygous baz germ-line clones undergo oogenesis, but the heterozygous progeny produced display major reductions in viability (Wieschaus and Noell).
Summary (Interactive Fly)
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
4

Please see the GBrowse view of Dmel\baz or the JBrowse view of Dmel\baz for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.52

Gene model reviewed during 5.47

Gene model reviewed during 6.11

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
baz-RA
FBtr0074388
NM_078659
6762
1464
baz-RB
FBtr0111000
NM_001042818
10439
1520
baz-RC
FBtr0343763
NM_001298435
6485
1499
baz-RD
FBtr0343764
NM_001298436
10334
1485
Additional Transcript Data and Comments
Reported size (kB)

6.7 (northern blot)

(Kuchinke et al., 1998)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
baz-PA
FBpp0074162
157.4
1464
9.18
NP_001334669
AAF48703
baz-PB
FBpp0110299
163.6
1520
9.17
NP_001036283
ABI30988
baz-PC
FBpp0310322
161.3
1499
8.95
NP_001285364
AHN59834
baz-PD
FBpp0310323
159.8
1485
9.36
NP_001285365
AHN59835
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)

1464 (aa)

(Kuchinke et al., 1998)
Comments

baz protein localizes to the anterior cytoplasm of stage 3 and 5 oocytes and does not overlap with par-1 protein.

(Vaccari and Ephrussi, 2002)
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\baz using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (50 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
phosphatidic acid binding
inferred from direct assay
(Yu and Harris, 2012)
phosphatidylinositol binding
inferred from direct assay
(Krahn et al., 2010)
protein binding
inferred from physical interaction with FLYBASE:Traf4; FB:FBgn0026319
(Wang et al., 2006)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
phosphatidylinositol binding
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (35 terms)
Terms Based on Experimental Evidence (22 terms)
CV Term
Evidence
References
adherens junction organization
inferred from high throughput genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VJ04
(assigned by UniProt )
(Shao et al., 2010)
apical protein localization
inferred from mutant phenotype
(Sotillos et al., 2008)
asymmetric neuroblast division
inferred from mutant phenotype
(Izumi et al., 2004)
inferred from genetic interaction with FLYBASE:pins; FB:FBgn0040080
(Cai et al., 2003)
asymmetric protein localization involved in cell fate determination
inferred from mutant phenotype
(Wang et al., 2006)
axis elongation
inferred from direct assay
(Simões et al., 2010)
border follicle cell delamination
inferred from mutant phenotype
(McDonald et al., 2008)
border follicle cell migration
inferred from mutant phenotype
(Aranjuez et al., 2012, Pinheiro and Montell, 2004)
branching involved in open tracheal system development
inferred from mutant phenotype
(Jones and Metzstein, 2011)
cell-cell adhesion involved in establishment of planar polarity
inferred from direct assay
(Simões et al., 2010)
establishment of apical/basal cell polarity
inferred from mutant phenotype
(Krahn et al., 2010, Hong et al., 2003)
establishment or maintenance of epithelial cell apical/basal polarity
inferred from mutant phenotype
(Harris and Peifer, 2005)
germ-band extension
inferred from mutant phenotype
(Zallen and Wieschaus, 2004)
germarium-derived oocyte fate determination
inferred from mutant phenotype
(Cox et al., 2001)
Malpighian tubule development
inferred from mutant phenotype
(Campbell et al., 2009)
negative regulation of filopodium assembly
inferred from mutant phenotype
(Georgiou and Baum, 2010)
oocyte anterior/posterior axis specification
inferred from mutant phenotype
(Doerflinger et al., 2010)
oocyte microtubule cytoskeleton organization
inferred from mutant phenotype
(Becalska and Gavis, 2010)
ovarian follicle cell-cell adhesion
inferred from mutant phenotype
(Abdelilah-Seyfried et al., 2003)
photoreceptor cell morphogenesis
inferred from mutant phenotype
(Chen et al., 2011)
regulation of establishment of planar polarity
inferred from genetic interaction with FLYBASE:dgo; FB:FBgn0086898
(Weber et al., 2012)
synapse assembly
inferred from mutant phenotype
(Ruiz-Canada et al., 2004)
zonula adherens assembly
inferred from mutant phenotype
(Harris and Peifer, 2004)
Terms Based on Predictions or Assertions (17 terms)
CV Term
Evidence
References
apical protein localization
non-traceable author statement
(Schaefer and Knoblich, 2001)
asymmetric cell division
traceable author statement
(Cheah et al., 2000)
basal protein localization
traceable author statement
(Peng et al., 2000)
cell adhesion
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
cell-cell junction assembly
non-traceable author statement
(Wedlich, 2002)
establishment of cell polarity
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
establishment of centrosome localization
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
establishment of mitotic spindle localization
traceable author statement
(Cheah et al., 2000)
establishment or maintenance of cell polarity
non-traceable author statement
(Humbert et al., 2003)
establishment or maintenance of epithelial cell apical/basal polarity
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
traceable author statement
(Muller, 2003)
non-traceable author statement
(Bachmann et al., 2001)
establishment or maintenance of neuroblast polarity
non-traceable author statement
(Bachmann et al., 2001)
establishment or maintenance of polarity of embryonic epithelium
non-traceable author statement
(Hong et al., 2001)
germ-band extension
traceable author statement
(Baum, 2004)
microtubule cytoskeleton organization
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
morphogenesis of a polarized epithelium
traceable author statement
(Gibson and Perrimon, 2003)
protein localization
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
zonula adherens assembly
traceable author statement
(Gibson and Perrimon, 2003, Muller, 2003)
Cellular Component (12 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
adherens junction
inferred from direct assay
(Morais-de-Sá et al., 2010, Harris and Peifer, 2005)
apical junction complex
inferred from direct assay
(Pilot et al., 2006)
apical plasma membrane
inferred from direct assay
(David et al., 2010)
cytoplasmic side of apical plasma membrane
inferred from direct assay
(Sotillos et al., 2008)
spot adherens junction
inferred from direct assay
(Harris and Peifer, 2004)
zonula adherens
inferred from direct assay
(Krahn et al., 2010, Krahn et al., 2010)
Terms Based on Predictions or Assertions (9 terms)
CV Term
Evidence
References
adherens junction
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
apical cortex
non-traceable author statement
(Hong et al., 2001)
traceable author statement
(Ohshiro et al., 2000)
apical junction complex
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
apical part of cell
non-traceable author statement
(Peng et al., 2000)
apical plasma membrane
non-traceable author statement
(Wedlich, 2002)
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
traceable author statement
(Gibson and Perrimon, 2003)
apicolateral plasma membrane
traceable author statement
(Tepass et al., 2001)
cell cortex
traceable author statement
(Bardin et al., 2004)
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN001046835
(assigned by GO_Central )
(Gaudet et al., 2011)
subapical complex
traceable author statement
(Gibson and Perrimon, 2003, Medina et al., 2002)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
epithelial cell | apical
(Kuchinke et al., 1998)
(Kuchinke et al., 1998)
neuroblast | apical
(Kuchinke et al., 1998)
Additional Descriptive Data

baz transcript is detected in early embryos and is expressed in a dynamic pattern during embryonic development. In gastrulating embryos, baz transcript is detected beneath the apical membrane in epithelial cells; later, a similar subcellular localization is detected in epithelial cells of the epidermis. In neuroblasts, expression is detected in a crest in the apical cytocortex (facing the epithelium).

(Kuchinke et al., 1998)
Marker for
 
Subcellular Localization
CV Term

cytoplasm | apical

(Kuchinke et al., 1998)
Polypeptide Expression
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female
germline cell
(Benton and St. Johnston, 2003)
immunohistochemistry
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
NMJ bouton
(Ruiz-Canada et al., 2004)
motor neuron
(Ruiz-Canada et al., 2004)
muscle cell

Comment: peribouton area

(Ruiz-Canada et al., 2004)
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
epithelial cell | apical
(Kuchinke et al., 1998)
neuroblast | apical
(Kuchinke et al., 1998)
scolopidial neuron | restricted
(Rolls and Doe, 2004)
oogenesis
follicle cell
(Morais-de-Sá et al., 2010)
follicle cell
(Morais-de-Sá et al., 2010)
adult stage | female & oogenesis
follicle stem cell
(Kronen et al., 2014)
follicle cell | apical
(Kronen et al., 2014)
oogenesis stage S3
oocyte | anterior
(Vaccari and Ephrussi, 2002)
oogenesis stage S5
oocyte | anterior
(Vaccari and Ephrussi, 2002)
embryonic stage 13 -- 14
Malpighian tubule Type II cell
(Campbell et al., 2010)
Additional Descriptive Data

baz protein is distributed diffusely in follicle stem cells, and is localized to the apical domain of downstream follicle cells.

(Kronen et al., 2014)

In stage 13 embryos baz is expressed in Malpighian tubule Type II (stellate) cells, particularly those that contact the tubule lumen. All Malpighian tubule Type II cells contact the luminal surface of the tubules in mid stage 14 and express high levels of baz as well as crb, shg, and dlg1.

(Campbell et al., 2010)

baz protein is detected at the apical cytocortex of epithelial cells such as the cells of the tracheal pit and epidermis. In neuroblasts, the protein is in a submembraneous crescent in the apical cytocortex. Expression is detected at metaphase but not at interphase.

(Morais-de-Sá et al., 2010, Kuchinke et al., 1998)

colocalizes with par-6 and aPKC presynaptically, and with par-6 in the postsynaptic peribouton area.

(Yu et al., 2004)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
adherens junction
inferred from direct assay
(Morais-de-Sá et al., 2010, Harris and Peifer, 2005)
apical junction complex
inferred from direct assay
(Pilot et al., 2006)
apical plasma membrane
inferred from direct assay
(David et al., 2010)
cytoplasmic side of apical plasma membrane
inferred from direct assay
(Sotillos et al., 2008)
spot adherens junction
inferred from direct assay
(Harris and Peifer, 2004)
zonula adherens
inferred from direct assay
(Krahn et al., 2010, Krahn et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\baz in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 37 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 86 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of baz
Transgenic constructs containing regulatory region of baz
Deletions and Duplications ( 23 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal, with Scer\GAL4Act5C.PI
lethal, with Scer\GAL4Act5C.PU
lethal, with Scer\GAL4e22c
lethal, with Scer\GAL4αTub84B.PL
lethal (with baz358-12)
lethal (with baz815-7)
lethal (with bazEH171)
lethal | embryonic stage
lethal | larval stage
lethal | recessive
lethal - all die before end of embryonic stage
lethal - all die before end of embryonic stage | maternal effect, with Scer\GAL4VP16.mat.αTub67C
lethal - all die before end of embryonic stage | recessive
partially lethal - majority die, with Scer\GAL4VP16.mat.αTub67C
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4477w-
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
female sterile | germline clone
fertile
Other Phenotypes
Allele
cell migration defective
cell polarity defective
cell polarity defective | somatic clone
cell shape defective
cell shape defective, with Scer\GAL4CY2
cell shape defective | somatic clone
increased cell death, with Scer\GAL4da.G32
neuroanatomy defective
neuroanatomy defective | larval stage, with Scer\GAL4C57
neurophysiology defective | larval stage, with Scer\GAL4C57, baz815-8
neurophysiology defective | larval stage, with Scer\GAL4C57, bazdsRNA.cRa.UAS
neurophysiology defective | larval stage (with baz815-8), with Scer\GAL4C57
neurophysiology defective | larval stage (with bazdsRNA.cRa.UAS), with Scer\GAL4C57
planar polarity defective
some die during embryonic stage
some die during embryonic stage, with Scer\GAL4VP16.mat.αTub67C
some die during embryonic stage | maternal effect, with Scer\GAL4VP16.mat.αTub67C
some die during embryonic stage | recessive
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
actomyosin
actomyosin, with Scer\GAL4332.3
adherens junction
adherens junction | pupal stage | somatic clone
amnioserosa
border follicle cell, with Scer\GAL4c306
border follicle cell, with Scer\GAL4slbo.2.6
border follicle cell, with Scer\GAL4slbo.2.6, baz4
border follicle cell, with Scer\GAL4slbo.2.6, bazdsRNA.Sym.UAS
border follicle cell, with Scer\GAL4slbo.2.6, Scer\GAL4upd1.PU
border follicle cell | somatic clone
bouton
dorsal appendage | germline clone | maternal effect
dorsal appendage | maternal effect, with Scer\GAL4VP16.mat.αTub67C
egg | maternal effect, with Scer\GAL4VP16.mat.αTub67C
egg chamber | germline clone
embryo
embryo | dorsal
embryo | gastrula stage
embryo | ventral
embryonic/first instar larval cuticle
embryonic/first instar larval cuticle, with Scer\GAL4arm.PS
embryonic/first instar larval cuticle, with Scer\GAL4VP16.mat.αTub67C
embryonic/first instar larval cuticle | germline clone
embryonic/first instar larval cuticle | maternal effect, with Scer\GAL4VP16.mat.αTub67C
embryonic/first instar larval cuticle | ventral
embryonic/larval cuticle
embryonic/larval neuromuscular junction, with Scer\GAL4C57
embryonic abdominal segment | germline clone | maternal effect
embryonic epidermis
embryonic epidermis, with Scer\GAL4da.G32
embryonic epidermis & spindle
embryonic ganglion mother cell
embryonic ganglion mother cell | germline clone
embryonic head
embryonic leading edge cell
embryonic Malpighian tubule
embryonic neuroblast & spindle | germ-line clone
epithelial cell | germline clone
eye, with Scer\GAL4GMR.PF
eye | somatic clone
eye disc | pupal stage
eye photoreceptor cell & eye disc & pupa | somatic clone
eye photoreceptor cell & eye disc & pupa | somatic clone | cell non-autonomous
follicle cell, with Scer\GAL4CY2
follicle cell, with Scer\GAL4T155
follicle cell | ectopic | somatic clone
follicle cell | germline clone
follicle cell | somatic clone
follicle cell | somatic clone, with Scer\GAL4Tub.PU
germ band | early extended germ band stage
germ band | gastrula stage
interommatidial cell | pupal stage | somatic clone | supernumerary
macrochaeta, with Scer\GAL4pnr-MD237
microtubule
microtubule, with Scer\GAL4unspecified
microtubule | germline clone
neuroblast | P-stage | somatic clone
NMJ bouton, with Scer\GAL4C57
nurse cell | germline clone
nurse cell fusome | germline clone
ommatidium | somatic clone
oocyte, with Scer\GAL4unspecified
oocyte & centrosome | germ-line clone
oocyte & microtubule | germ-line clone
oocyte | germline clone
oocyte nucleus
oocyte nucleus, with Scer\GAL4VP16.mat.αTub67C
oocyte nucleus | germline clone
photoreceptor cell & eye | somatic clone
plasma membrane, with Scer\GAL4ap.PU
presumptive embryonic/larval central nervous system
presumptive embryonic/larval nervous system
spot adherens junction
terminal tracheal cell | somatic clone
trichogen cell | supernumerary, with Scer\GAL4pnr-MD237
zonula adherens
zonula adherens | somatic clone
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\PARD3
12 of 15
Yes
Yes
Hsap\PARD3B
9 of 15
No
Yes
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Pard3
11 of 15
Yes
Yes
Mmus\Pard3b
9 of 15
No
Yes
Rattus norvegicus (Norway rat) (2)
Rnor\Pard3b
7 of 13
Yes
Yes
Rnor\Pard3
7 of 13
Yes
Yes
Xenopus tropicalis (Western clawed frog) (2)
Xtro\pard3
5 of 12
Yes
Yes
Xtro\pard3b
4 of 12
No
Yes
Danio rerio (Zebrafish) (4)
Drer\pard3bb
7 of 15
Yes
Yes
Drer\pard3ab
5 of 15
No
Yes
Drer\pard3aa
3 of 15
No
Yes
Drer\pard3ba
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\par-3
8 of 15
Yes
Yes
Cele\magi-1
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG0919020L )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\baz
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00008176
Drosophila simulans
Dsim\GD17331
Drosophila sechellia
Dsec\GM13492
Drosophila erecta
Dere\GG19100
Drosophila yakuba
Dyak\GE17646
Drosophila ananassae
Dana\GF22322
Drosophila pseudoobscura pseudoobscura
Dpse\GA18624
Drosophila persimilis
Dper\GL19872
Drosophila willistoni
Dwil\GK25801
Drosophila virilis
Dvir\GJ14885
Drosophila mojavensis
Dmoj\GI16958
Drosophila grimshawi
Dgri\GH12056
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500U3 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17024796
Glossina morsitans
Tsetse fly
Gmor\GMOY007310
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_13773
Mayetiola destructor
Hessian fly
Mdes\Mdes005266
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL007658
Anopheles darlingi
American malaria mosquito
Adar\ADAC008276
Anopheles gambiae
Malaria mosquito
Agam\AGAP000869
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ003808
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02WD )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA006557
Danaus plexippus
Monarch butterfly
Dple\DPOGS213816-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL016161
Apis florea
Little honeybee
Aflo\2941307268
Apis mellifera
Western honey bee
Amel\GB40100
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP21682
Bombus terrestris
Buff-tailed bumblebee
Bter\15205194
Linepithema humile
Argentine ant
Lhum\LH22099
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00184e
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG006266
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08030
Tribolium castaneum
Red flour beetle
Tcas\TC034318
Pediculus humanus
Human body louse
Phum\PHUM257850
Rhodnius prolixus
Kissing bug
Rpro\RPRC004878
Rhodnius prolixus
Kissing bug
Rpro\RPRC001227
Cimex lectularius
Bed bug
Clec\CLEC000665
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003311
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_04429
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X02T6 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR011645
Ixodes scapularis
Black-legged tick
Isca\ISCW015964
Stegodyphus mimosarum
African social velvet spider
Smim\KFM58977.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM66848.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur03g03780
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_34788
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_31747
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G04AU )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Par3ph2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Par3ph1
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000020218
Gallus gallus
Domestic chicken
Ggal\PARD3
Gallus gallus
Domestic chicken
Ggal\Gga.25117
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (6)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
a
1 of 10
bbg
1 of 10
CG15803
1 of 10
Grip
1 of 10
inaD
1 of 10
Patj
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
baz4
model of  cancer
CEA with Ras85DV12.UAS
(Pagliarini and Xu, 2003)
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 2 )
Allele
Disease
Interaction
References
bazUAS.cKa
ameliorates  hematologic cancer
modeled by hopTum
(Bina et al., 2010)
bazGD1384
ameliorates  hematologic cancer
modeled by hopTum
(Bina et al., 2010)
Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
PARD3; par-3 family cell polarity regulator
12 of 15
606745
      PARD3B; par-3 family cell polarity regulator beta
      9 of 15
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Show neighbor-neighbor interactions:
          Select Layout:
          Legend:
          Protein
          RNA
          Selected Interactor(s)
          Interactions Browser
          View in Interactions Browser
          Please see the Physical Interaction reports below for full details
          protein-protein
          Physical Interaction
          Assay
          References
          baz
          anti tag coimmunoprecipitation, anti tag western blot, cross-linking study, western blot
          (Kullmann and Krahn, 2018)
          baz - 14-3-3ε
          anti tag coimmunoprecipitation, anti tag western blot
          (Krahn et al., 2009)
          baz - Dlic
          anti tag coimmunoprecipitation, western blot
          (Jouette et al., 2019)
          baz - Magi
          proximity ligation assay, fluorescence microscopy, anti bait coimmunoprecipitation, western blot
          (Padash Barmchi et al., 2016)
          baz - Mbs
          anti tag coimmunoprecipitation, western blot
          (Sen et al., 2015)
          baz - Patj
          anti bait coimmunoprecipitation, western blot
          (Sen et al., 2015)
          baz - Pp2A-29B
          two hybrid, anti bait coimmunoprecipitation, western blot, anti tag western blot
          (Krahn et al., 2009)
          baz - Pten
          two hybrid, anti tag coimmunoprecipitation, anti tag western blot
          (von Stein et al., 2005)
          baz - Src42A
          anti tag coimmunoprecipitation, anti tag western blot
          (Sotillos et al., 2013)
          baz - Stat92E
          anti tag coimmunoprecipitation, western blot, pull down, autoradiography
          (Sotillos et al., 2013, Sotillos et al., 2008)
          baz - Traf4
          pull down, autoradiography
          (Mathew et al., 2011, Wang et al., 2006)
          baz - aPKC
          anti bait coimmunoprecipitation, western blot, anti tag coimmunoprecipitation, anti tag western blot, two hybrid, pull down, protein kinase assay, autoradiography
          (Casas-Tintó and Ferrús, 2019, Padash Barmchi et al., 2016, Goh et al., 2013, Duchi et al., 2010, Morais-de-Sá et al., 2010, Simões et al., 2010, Kim et al., 2009, Krahn et al., 2009, Wirtz-Peitz et al., 2008, Wang and Riechmann, 2007, Djiane et al., 2005, Harris and Peifer, 2005, Betschinger et al., 2003, Wodarz et al., 2000)
          baz - arm
          pull down, autoradiography, anti bait coimmunoprecipitation, western blot, two hybrid
          (Wei et al., 2005)
          baz - clu
          anti bait coimmunoprecipitation, western blot
          (Goh et al., 2013)
          baz - crb
          pull down, autoradiography
          (Kolsch et al., 2007)
          baz - cyst
          anti tag coimmunoprecipitation, anti tag western blot
          (Silver et al., 2019)
          baz - dsh
          anti tag coimmunoprecipitation, anti tag western blot
          (Banerjee et al., 2017)
          baz - ed
          anti bait coimmunoprecipitation, western blot, pull down, autoradiography, two hybrid
          (Wei et al., 2005)
          baz - fz
          anti tag coimmunoprecipitation, western blot, anti tag western blot
          (Banerjee et al., 2017, Djiane et al., 2005)
          baz - insc
          anti tag coimmunoprecipitation, western blot, anti bait coimmunoprecipitation, pull down, autoradiography
          (Schober et al., 1999, Wodarz et al., 1999)
          baz - meru
          anti tag coimmunoprecipitation, anti tag western blot
          (Banerjee et al., 2017)
          baz - mira
          pull down, anti tag western blot
          (Wirtz-Peitz et al., 2008)
          baz - mts
          anti bait coimmunoprecipitation, western blot, Identification by mass spectrometry
          (Krahn et al., 2009)
          baz - numb
          pull down, western blot
          (Wirtz-Peitz et al., 2008)
          baz - par-6
          pull down, anti tag western blot, autoradiography, molecular weight estimation by staining, western blot, anti bait coimmunoprecipitation
          (Morais-de-Sá et al., 2010, Wirtz-Peitz et al., 2008, Hutterer et al., 2004, Peterson et al., 2004, Betschinger et al., 2003, Petronczki and Knoblich, 2001)
          baz - pon
          pull down, anti tag western blot
          (Wirtz-Peitz et al., 2008)
          baz - sdt
          anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation, western blot, pull down
          (Koch et al., 2016, Sen et al., 2015, Krahn et al., 2010)
          baz - shg
          anti bait coimmunoprecipitation, western blot
          (Bulgakova et al., 2013, Harris and Peifer, 2005)
          baz - sktl
          anti tag coimmunoprecipitation, anti tag western blot
          (Jouette et al., 2019)
          baz - smash
          two hybrid, nuclear magnetic resonance, predetermined participant, anti tag coimmunoprecipitation, western blot
          (Beati et al., 2018)
          baz - sqh
          anti bait coimmunoprecipitation, western blot
          (Wang and Riechmann, 2007)
          baz - stan
          pull down, western blot
          (Wasserscheid et al., 2007)
          baz - stau
          anti bait coimmunoprecipitation, western blot
          (Wodarz et al., 1999)
          baz - tws
          anti tag coimmunoprecipitation, anti tag western blot
          (Krahn et al., 2009)
          baz - wrd
          anti tag coimmunoprecipitation, anti tag western blot
          (Krahn et al., 2009)
          baz - wts
          coimmunoprecipitation, anti tag western blot
          (Keder et al., 2015)
          baz - wupA
          anti bait coimmunoprecipitation, western blot
          (Casas-Tintó and Ferrús, 2019)
          baz - α-Cat
          anti bait coimmunoprecipitation, western blot
          (Bulgakova et al., 2013)
          Summary of Genetic Interactions
          esyN Network Diagram
          esyN Network Key:
          Suppression
          Enhancement
          View in Interactions Browser
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          baz
          enhanceable
          alt
          (Shao et al., 2010)
          baz
          enhanceable
          aPKC
          (Shao et al., 2010)
          baz
          enhanceable
          Arf79F
          (Shao et al., 2010)
          baz
          enhanceable
          Asap
          (Shao et al., 2010)
          baz
          enhanceable
          asp
          (Shao et al., 2010)
          baz
          enhanceable
          CG1951
          (Shao et al., 2010)
          baz
          enhanceable
          CG5823
          (Shao et al., 2010)
          baz
          enhanceable
          CG10702
          (Shao et al., 2010)
          baz
          enhanceable
          cnn
          (Chen et al., 2011)
          baz
          enhanceable
          crb
          (Shao et al., 2010)
          baz
          enhanceable
          Cul5
          (Shao et al., 2010)
          baz
          enhanceable
          Dcr-2
          (Dietzl et al., 2007)
          baz
          enhanceable
          Dhc64C
          (Harris and Peifer, 2005)
          baz
          enhanceable
          ed
          (Shao et al., 2010)
          baz
          enhanceable
          fj
          (Shao et al., 2010)
          baz
          enhanceable
          hook
          (Shao et al., 2010)
          baz
          suppressible
          l(2)gl
          (Krahn et al., 2010)
          baz
          enhanceable
          meru
          (Banerjee et al., 2017)
          baz
          enhanceable
          muskelin
          (Shao et al., 2010)
          baz
          enhanceable
          par-1
          (Shao et al., 2010)
          baz
          enhanceable
          par-6
          (Pinheiro and Montell, 2004)
          baz
          enhanceable
          Rho1
          (Shao et al., 2010)
          baz
          enhanceable
          Roc2
          (Shao et al., 2010)
          baz
          suppressible
          scrib
          (Krahn et al., 2010)
          baz
          enhanceable
          sds22
          (Shao et al., 2010)
          baz
          enhanceable
          Sep5
          (Shao et al., 2010)
          baz
          enhanceable
          shg
          (Shao et al., 2010)
          baz
          enhanceable
          Tmem63
          (Shao et al., 2010)
          baz
          enhanceable
          zip
          (David et al., 2010)
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          aPKC
          suppressible
          baz
          (Jiang et al., 2015)
          aurA
          suppressible
          baz
          (Wirtz-Peitz et al., 2008)
          dgo
          enhanceable
          baz
          (Weber et al., 2012)
          dlg1
          suppressible
          baz
          (Abdelilah-Seyfried et al., 2003)
          Fmr1
          enhanceable
          baz
          (Zarnescu et al., 2005)
          H
          suppressible
          baz
          (Müller et al., 2005)
          hop
          suppressible
          baz
          (Bina et al., 2010)
          l(2)gl
          enhanceable
          baz
          (Wirtz-Peitz et al., 2008)
          l(2)gl
          suppressible
          baz
          (Wirtz-Peitz et al., 2008)
          meru
          enhanceable
          baz
          (Banerjee et al., 2017)
          par-6
          enhanceable
          baz
          (Pinheiro and Montell, 2004)
          Ras85D
          enhanceable
          baz
          (Pagliarini and Xu, 2003)
          sktl
          enhanceable
          baz
          (Gervais et al., 2008)
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          X
          Recombination map

          1-57

          Cytogenetic map
          15F1-15F1
          Sequence location
          X:17,160,006..17,200,728 [+]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          15F1-15F1
          Limits computationally determined from genome sequence between P{EP}EP1337 and P{EP}bazEP1446
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          15F-15F
          (determined by in situ hybridisation)
          (Peter et al., 2002, Schäfer et al., 1999.12.2)
          15E-15F
          (Knust, 1998.11.17, Kuchinke et al., 1996)
          Experimentally Determined Recombination Data
          Location

          1-57

          (FlyBase, 2016)

          1-57.4

          (Comeron et al., 2012)

          1-56.7

          (Tearle and Nusslein-Volhard, 1987)
          Left of (cM)
          (Kuchinke et al., 1996)
          Right of (cM)
          (Becalska and Gavis, 2010)
          Notes
          Stocks and Reagents
          Stocks (28)
          Genomic Clones (24)
          cDNA Clones (70)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequences
          BDGP DGC clones
          Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
            RNAi and Array Information
            Linkouts
            DRSC - Results frm RNAi screens
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            Antibody Information
            Other Information
            Relationship to Other Genes
            Source for database identify of
            Source for database merge of

            Source for merge of: baz l(1)G0484

            (Peter et al., 2002)
            Additional comments

            "l(1)G0497" may affect "baz". "l(1)G0313" may affect "baz".

            (Peter et al., 2002)
            Other Comments

            baz is required for cell rearrangement and spatially regulated contractile behavior during axis elongation.

            (Simões et al., 2010)

            The C-terminal domain of baz is necessary for baz planar polarity.

            (Simões et al., 2010)

            baz acts upstream of adherens junctions as epithelial polarity is established during cellularization.

            (Harris and Peifer, 2004)

            baz acts as a permissive factor during cell invasion in the follicle cells. baz function is dispensable fro cell invasion and motility but is required cell-autonomously in mediating cell adhesion within the migrating border cell cluster.

            (Abdelilah-Seyfried et al., 2003)

            baz is required for the establishment of apical-basal polarity in eye photoreceptors during early pupal stages.

            (Hong et al., 2003)

            dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

            (Kiger et al., 2003)

            RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in Kc167 and S2R+ cells: binucleate cells.

            (Kiger et al., 2003)

            baz is required for par-1 relocalization within the oocyte.

            (Vaccari and Ephrussi, 2002)

            baz, raps and dlg1 establish and maintain planar polarity in pI cells.

            (Bellaiche et al., 2001)

            baz and par-6 proteins are interdependent for their asymmetric localisation at the apical cell cortex of epithelial cells and neuroblasts in the embryo.

            (Petronczki and Knoblich, 2001)

            Apical localisation of insc protein in embryonic neuroblasts requires baz.

            (Schober et al., 1999)

            Localisation of insc protein depends on baz.

            (Wodarz et al., 1999)

            baz is likely to be part of a regulatory mechanism required to coordinate the axis of polarity of a cell with that of the embryo.

            (Kuchinke et al., 1998)

            Embryos mutant for arm and sdt baz double mutant embryos have very similar early phenotypes with respect to zonula adherens formation. Results suggest that early stages in the assembly of the zonula adherens are critical for the stability of the polarised blastoderm epithelium.

            (Muller and Wieschaus, 1996)

            A screen for X-linked genes that affect embryo morphology revealed baz.

            (Eberl and Hilliker, 1988)

            baz mutants display a large dorsal hole and ventral hole.

            (Wieschaus et al., 1984)
            Origin and Etymology
            Discoverer
            Etymology
            Identification
            External Crossreferences and Linkouts ( 57 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            modMine - A data warehouse for the modENCODE project
            SignaLink - A signaling pathway resource with multi-layered regulatory networks.
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            FLIGHT - Cell culture data for RNAi and other high-throughput technologies
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyMine - An integrated database for Drosophila genomics
            Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
            MIST (genetic) - An integrated Molecular Interaction Database
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Synonyms and Secondary IDs (21)
            Reported As
            Symbol Synonym
            BAZ
            (Baril et al., 2014, Claret et al., 2014)
            Baz
            (Bonello and Peifer, 2019, Brantley and Fuller, 2019, Hannaford et al., 2019, Nunes de Almeida et al., 2019, Pütz, 2019, Zhang et al., 2019, Bonello et al., 2018, Carmena, 2018, Wang et al., 2018, Choubey and Roy, 2017, Richardson and Portela, 2017, Trylinski et al., 2017, Ajduk and Zernicka-Goetz, 2016, Flores-Benitez and Knust, 2016, Koch et al., 2016, Moreira and Morais-de-Sá, 2016, Schimizzi et al., 2016, Soriano et al., 2016, Veeman and McDonald, 2016, Yadav et al., 2016, Yasugi and Nishimura, 2016, Bell et al., 2015, Campbell and Casanova, 2015, Flores-Benitez and Knust, 2015, Jiang et al., 2015, Lan et al., 2015, Ohno et al., 2015, Schweisguth, 2015, Wang et al., 2015, Claret et al., 2014, Kumichel and Knust, 2014, Mauri et al., 2014, Pichaud, 2014, Simões et al., 2014, Skwarek et al., 2014, Thomas and Strutt, 2014, Zhang et al., 2014, Chai et al., 2013, Chen and Zhang, 2013, Desai et al., 2013, Goh et al., 2013, Guillot and Lecuit, 2013, Haack et al., 2013, Morais-de-Sá and Sunkel, 2013, Noatynska et al., 2013, Pérez-Gómez et al., 2013, Sotillos et al., 2013, Yu and Guan, 2013, Andersen et al., 2012, Bosveld et al., 2012, Fichelson et al., 2012, Giagtzoglou et al., 2012, Guilgur et al., 2012, Gurudatta et al., 2012, Homem and Knoblich, 2012, Penalva and Mirouse, 2012, Sarpal et al., 2012, Sen et al., 2012, Tamada et al., 2012, Tepass, 2012, Zhou and Hong, 2012, Genevet and Tapon, 2011, Laplante and Nilson, 2011, Laprise, 2011, Laprise and Tepass, 2011, Mathew et al., 2011, Mukai et al., 2011, Nance and Zallen, 2011, Sun et al., 2011, Wang et al., 2011, Campbell et al., 2010, David et al., 2010, Gandille et al., 2010, Georgiou and Baum, 2010, Gervais and Casanova, 2010, Januschke and Gonzalez, 2010, Morais-de-Sá et al., 2010, Mukhopadhyay et al., 2010, Nilton et al., 2010, Simone and DiNardo, 2010, Walther and Pichaud, 2010, Zeng et al., 2010, Cabernard and Doe, 2009, Chabu and Doe, 2009, Fernandez-Gonzalez et al., 2009, Kessler and Müller, 2009, Kim et al., 2009, McGill et al., 2009, Roeth et al., 2009, Wang et al., 2009, Chabu and Doe, 2008, Denef et al., 2008, Horne-Badovinac and Bilder, 2008, Huang et al., 2008, Krahn and Wodarz, 2008, Li et al., 2008, Siller and Doe, 2008, Spasić et al., 2008, Speicher et al., 2008, Wirtz-Peitz et al., 2008, Xu et al., 2008, Yamashita and Fuller, 2008, Blankenship et al., 2007, Bonaccorsi et al., 2007, Chandraratna et al., 2007, Grzeschik et al., 2007, Harris and Peifer, 2007, Kolsch et al., 2007, Lee et al., 2007, Nam et al., 2007, Wang and Riechmann, 2007, Wirtz-Peitz et al., 2007, Balakireva et al., 2006, Blankenship et al., 2006, Lee et al., 2006, Lee et al., 2006, Nam and Choi, 2006, O'Reilly et al., 2006, Pilot et al., 2006, Schneider et al., 2006, Siegrist and Doe, 2006, Wang et al., 2006, Wang et al., 2006, Becam et al., 2005, David et al., 2005, Jafar-Nejad et al., 2005, Langevin et al., 2005, Le Bivic, 2005, Siegrist and Doe, 2005, Wang et al., 2005, Wei et al., 2005, Yamashita et al., 2005, Harris and Peifer, 2004, Wei et al., 2004, Wu and Beitel, 2004)
            Baz/Par-3
            (Fehon, 2006)
            Baz/Par3
            (Georgiou and Baum, 2010)
            Bazooka
            (Khadilkar and Tanentzapf, 2019, Osterfield et al., 2015, Bergstralh et al., 2013, Muha and Müller, 2013, Kelsom and Lu, 2012, Nakano and Takashima, 2012, Laprise, 2011, Wirtz-Peitz and Knoblich, 2006)
            CG5055
            (Hosono et al., 2015, Rosa-Ferreira et al., 2015, Haelterman et al., 2014, Christis and Munro, 2012, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Ni et al., 2008)
            D-Par3
            (Weber et al., 2012, Pichaud et al., 2006)
            D-par3
            (Pinal et al., 2006)
            PAR-3
            (Jouette et al., 2017, Gross et al., 2013, Li, 2013, Baffet et al., 2012, McKinley and Harris, 2012, Halbsgut et al., 2011, Krahn et al., 2010, McDonald et al., 2008, Solecki et al., 2006, Suzuki and Ohno, 2006, Harris and Peifer, 2005, Wei et al., 2005, Lecuit, 2004)
            PAR3
            (Jouette et al., 2019, Nakano and Takashima, 2012, Saini and Reichert, 2012, Baas et al., 2004)
            Par-3
            (Paré et al., 2019, Hong, 2018, Lang and Munro, 2017, Liu and Jin, 2017, Yu and Fernandez-Gonzalez, 2017, Vichas et al., 2015, Simões et al., 2014, Bulgakova et al., 2013, Lu and Johnston, 2013, Muha and Müller, 2013, Kelsom and Lu, 2012, Yu and Harris, 2012, Zhou and Hong, 2012, David et al., 2010, Franz and Riechmann, 2010, Chabu and Doe, 2009, Chabu et al., 2007, Lecuit and Le Goff, 2007, Pilot et al., 2006, Yamashita et al., 2005, Betschinger and Knoblich, 2004, Macara, 2004, Roegiers and Jan, 2004, Sotillos et al., 2004, Doe, 2001)
            Par3
            (Kono et al., 2019, Roman-Fernandez and Bryant, 2016, Bajaj et al., 2015, Bell et al., 2015, Cao et al., 2015, Bardet et al., 2013, Desai et al., 2013, Guillot and Lecuit, 2013, Truong Quang et al., 2013, Baffet et al., 2012, Guilgur et al., 2012, Sarpal et al., 2012, Levayer et al., 2011, Georgiou and Baum, 2010, Leatherman and Dinardo, 2010, Shao et al., 2010, Simone and DiNardo, 2010, Chia et al., 2008, Georgiou et al., 2008, Yamashita and Fuller, 2008, Garcia-Mata and Burridge, 2007, Speicher et al., 2007, Humbert et al., 2006, Pilot et al., 2005, Gibson and Perrimon, 2003)
            baz
            (Balaji et al., 2019, Guan et al., 2019, Jiang et al., 2019, Meltzer, 2019-, Meltzer et al., 2019, Nelson et al., 2019, Silver et al., 2019, Singh et al., 2019, Beati et al., 2018, Zoranovic et al., 2018, Banerjee et al., 2017, Herzmann et al., 2017, Hsu and Drummond-Barbosa, 2017, Stessman et al., 2017, Aigouy and Le Bivic, 2016, Clandinin and Owens, 2016-, Liu et al., 2016, Padash Barmchi et al., 2016, Walther et al., 2016, Xu et al., 2016, Besson et al., 2015, Keder et al., 2015, Le Droguen et al., 2015, Osterfield et al., 2015, Sen et al., 2015, Zaessinger et al., 2015, Ashwal-Fluss et al., 2014, Haelterman et al., 2014, Jiang et al., 2014, Morais-de-Sá et al., 2014, Parsons et al., 2014, Razzell et al., 2014, Zhou et al., 2014, Bulgakova et al., 2013, Desai et al., 2013, Gross et al., 2013, Homem et al., 2013, Jauffred et al., 2013, Leibfried et al., 2013, Osterfield et al., 2013, Pickering et al., 2013, Andersen et al., 2012, Aranjuez et al., 2012, Hazelett et al., 2012, McKinley et al., 2012, Robertson et al., 2012, Speese et al., 2012, Weber et al., 2012, Chen et al., 2011, Goossens et al., 2011, Halbsgut et al., 2011, Jones and Metzstein, 2011, Li et al., 2011, Ohsawa et al., 2011, Rodrigues et al., 2011, Sawyer et al., 2011, Tio et al., 2011, Toku et al., 2011, Becalska and Gavis, 2010, Bina et al., 2010, Chang et al., 2010, David et al., 2010, Doerflinger et al., 2010, Duchi et al., 2010, Fichelson et al., 2010, Franz and Riechmann, 2010, Januschke and Gonzalez, 2010, Kitajima et al., 2010, Krahn et al., 2010, Krahn et al., 2010, Shao et al., 2010, Simões et al., 2010, Bottenberg et al., 2009, Courbard et al., 2009, Hazelett et al., 2009, Ramachandran et al., 2009, Southall and Brand, 2009, Fernandez-Minan et al., 2008, Georgiou et al., 2008, Harris and Tepass, 2008, Horne-Badovinac and Bilder, 2008, Leibfried et al., 2008, Llense and Martín-Blanco, 2008, O'Reilly et al., 2008, Pope and Harris, 2008, Wirtz-Peitz et al., 2008, Wirtz-Peitz et al., 2008, Atwood et al., 2007, Buszczak et al., 2007, Choi et al., 2007, Dietzl et al., 2007, Heger and Ponting, 2007, Hueber et al., 2007, Szafranski and Goode, 2007, Wang and Riechmann, 2007, Wasserscheid et al., 2007, Bayraktar et al., 2006, Djiane et al., 2006, Pinal et al., 2006, Suzuki and Ohno, 2006, Ahringer, 2005, Djiane et al., 2005, Harris and Peifer, 2005, Jafar-Nejad et al., 2005, Lipatov et al., 2005, Lu and Bilder, 2005, Wiggin et al., 2005, Zarnescu et al., 2005, Harris and Peifer, 2004, Hutterer et al., 2004, Rolls and Doe, 2004, Rath et al., 2002, Wodarz et al., 1999)
            bazooka
            (Sherrard and Fehon, 2015, Miles et al., 2011, Humbert et al., 2006)
            dPar-3
            (Skeath and Thor, 2003)
            l(1)G0484
            (Schäfer et al., 1999.12.2)
            par-3
            (Le Droguen et al., 2015, Bulgakova et al., 2012, Fichelson et al., 2010, Sotillos et al., 2008, Breuer et al., 2005, Gotta, 2005, Rodriguez-Boulan et al., 2004)
            par3
            (Osterfield et al., 2015, Sherrard and Fehon, 2015)
            Name Synonyms
            Baz
            (Pichaud, 2018)
            Bazooka
            (Das Gupta and Narasimha, 2019, Saito et al., 2018, Schmidt and Grosshans, 2018, Curran et al., 2017, Gilmour et al., 2017, Harris, 2017, Kong et al., 2017, Yamamoto et al., 2017, Koch et al., 2016, Liu et al., 2016, Moreira and Morais-de-Sá, 2016, Soriano et al., 2016, Xu et al., 2016, Bell et al., 2015, Campbell and Casanova, 2015, Peterson and Krasnow, 2015, Sen et al., 2015, Parsons et al., 2014, Zhang et al., 2014, Bardet et al., 2013, Bulgakova et al., 2013, Chen and Zhang, 2013, Culurgioni and Mapelli, 2013, Desai et al., 2013, Enderle and McNeill, 2013, Goh et al., 2013, Gross et al., 2013, Wang et al., 2013, Yu and Guan, 2013, Couturier et al., 2012, Guilgur et al., 2012, McKinley and Harris, 2012, Sarpal et al., 2012, Zhou and Hong, 2012, Laplante and Nilson, 2011, Levayer et al., 2011, Li et al., 2011, Sun et al., 2011, David et al., 2010, Forster et al., 2010, Franz and Riechmann, 2010, Krahn et al., 2010, Morais-de-Sá et al., 2010, Nilton et al., 2010, Simões et al., 2010, Simone and DiNardo, 2010, Walther and Pichaud, 2010, Campbell et al., 2009, Chabu and Doe, 2009, Coumailleau et al., 2009, Kessler and Müller, 2009, Kim et al., 2009, Krahn et al., 2009, McGill et al., 2009, Ramachandran et al., 2009, Chia et al., 2008, Harris and Tepass, 2008, Horne-Badovinac and Bilder, 2008, Krahn and Wodarz, 2008, Leibfried et al., 2008, Li et al., 2008, Llense and Martín-Blanco, 2008, McDonald et al., 2008, Speicher et al., 2008, Wirtz-Peitz et al., 2008, Xu et al., 2008, Atwood et al., 2007, Blankenship et al., 2007, Bonaccorsi et al., 2007, Chandraratna et al., 2007, Kohsaka et al., 2007, Lecuit and Le Goff, 2007, Nam et al., 2007, Nam et al., 2007, Speicher et al., 2007, Wang and Riechmann, 2007, Wilson et al., 2007, Ataman et al., 2006, Blankenship et al., 2006, Choksi et al., 2006, Laprise et al., 2006, Muschalik et al., 2006, Nam and Choi, 2006, Pichaud et al., 2006, Pinal et al., 2006, Suzuki and Ohno, 2006, Wang et al., 2006, Becam et al., 2005, Margolis and Borg, 2005, Somers and Chia, 2005, Wei et al., 2005, Yamashita et al., 2005, Franchini et al., 2004, Harris and Peifer, 2004, Lecuit, 2004, Roegiers and Jan, 2004, von Stein et al., 2003)
            Bazooka-Par3
            (Lin, 2008)
            Bazooka/Par-3
            (Fehon, 2006)
            Bazooka/Par3
            (Ly et al., 2017, Sarpal et al., 2012)
            bazooka
            (Takeda et al., 2018, Herzmann et al., 2017, Ng et al., 2016, Wieschaus and Nüsslein-Volhard, 2016, Le Droguen et al., 2015, Ohno et al., 2015, Taniguchi et al., 2014, Zhou et al., 2014, Bulgakova et al., 2013, Desai et al., 2013, Aranjuez et al., 2012, Paré et al., 2012, Wang et al., 2012, Weber et al., 2012, Yu and Harris, 2012, Chen et al., 2011, Furman and Bukharina, 2011, Spindler and Hartenstein, 2011, Tio et al., 2011, Becalska and Gavis, 2010, Fichelson et al., 2010, Kitajima et al., 2010, Shao et al., 2010, Mummery-Widmer et al., 2009, Fernandez-Minan et al., 2008, Harris and Tepass, 2008, O'Reilly et al., 2008, Choi et al., 2007, Wasserscheid et al., 2007, Burnette et al., 2005, Harris and Peifer, 2005, Lu and Bilder, 2005, Rath et al., 2002, Knust, 1998.11.17, Kuchinke et al., 1997)
            par-3
            (Le Droguen et al., 2015)
            Secondary FlyBase IDs
            • FBgn0040145
            • FBgn0042632
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (620)