A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Dmel\brc

General Information
SymbolDmel\brcSpeciesD. melanogaster
NamebrachymacrochaetaeAnnotation symbol
Feature typegeneFlyBase IDFBgn0000214
Gene Model StatusUnannotated Stock availability None publicly available
Also Known AsC93
Genomic Location
Chromosome (arm)Recombination map1-0.0
Cytogenetic map1C3-1D4Sequence location
hide Summary Information
Automatically generated summary

See sections below for more information
The gene brachymacrochaetae is referred to in FlyBase by the symbol Dmel\brc (FBgn0000214). It is a gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: oogenesis. 12 alleles are reported. The phenotypes of these alleles are annotated with: scutellar bristle; macrochaeta; dorsocentral bristle; mesothoracic bristle. It has no annotated transcripts. Gene has not been localized to the genome sequence.

User Contributed Data
hide Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage
brc: brachymacrochaetae
One or more thoracic bristle much reduced in size; scutellars and dorsocentrals most frequently affected. Occasional bristles duplicated. Extra-bristle phenotype enhanced by duplications for the tip of X with breakpoint between su(s) and tw (Maddern, 1972, DIS 49: 40). Good viability and fertility in both sexes. brc6, a lethal allele, causes pupal death with substantial pupal histolysis, especially at anterior end (Eberl, Hilliker, and Voelker, 1988, DIS 67: 36).
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Description
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FB2013_03
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hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
1C3-1D4  
Left limit from non-inclusion within Df(1)yT18-319 (citation unavailable) Right limit from inclusion within Df(1)su(s)83 (FBrf0049919)  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
 
Mapped between su(s) and tw by duplication analysis (details unspecified).  
(Maddern, 1972)
Experimentally Determined Recombination Data
Location
1-0.0
(Fahmy and Fahmy, 1958)
Left of (cM)
(Maddern, 1972)
Right of (cM)
(Maddern, 1972)
Notes
No recombinants with sc among 6746 sons.
 
No crossing over with sc (0/6746).
(Fahmy and Fahmy, 1958)
hide Gene Model & Products
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
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Type
Symbol & Location
Additional Notes
References
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Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
hide Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term
Evidence
References
hide Expression Deduced from Reporters
hide High-Throughput Expression Data
Associated Tools
Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
hide FlyAtlas Anatomy Microarray
hide modENCODE Anatomy RNA-Seq
hide modENCODE Development RNA-Seq
hide modENCODE Cell Lines RNA-Seq
hide modENCODE Treatments RNA-Seq
hide Expression Clusters
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Linkouts
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
lethal | polyphasic
lethal | polyphasic | recessive
lethal | pupal stage
lethal | pupal stage | recessive
lethal | recessive
partially lethal - majority die | recessive
viable
Sterility
Allele
fertile
Other Phenotypes
Allele
visible | recessive
Phenotype manifest in
Allele
dorsocentral bristle
macrochaeta
macrochaeta & thorax
mesothoracic bristle
scutellar bristle
hide Classical Alleles ( 12 )
For All Classical Alleles Show

Allele of brcClassMutagenStocksKnown lesion
brc100 --
brc110 --
brc120 --
brc10 --
brc20 --
brc30 --
brc40 --
brc50 --
brc60 --
brc70 --
brc80 --
brc90 --
hide Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show

Allele of brcClassMutagenStocksKnown lesion
hide Aneuploid Aberrations
Duplicated in
(Kramers et al., 1983, Kramers et al., 1991)
(Schalet, 1986)
Not disrupted in
(Kramers et al., 1991)
(Kramers et al., 1983, Kramers et al., 1991)
(Kramers et al., 1991)
(Schalet, 1986)
(Kramers et al., 1983, Kramers et al., 1991)
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(Schalet, 1986)
(Kramers et al., 1983, Kramers et al., 1991)
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(Voelker et al., 1989)
(Kramers et al., 1983, Voelker et al., 1989, Kramers et al., 1991)
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Not duplicated in
(Kramers et al., 1983, Kramers et al., 1991)
Disrupted in
(Voelker et al., 1989)
(Voelker et al., 1989)
(Voelker et al., 1989)
(Voelker et al., 1989)
(Voelker et al., 1989)
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
Insertions
Type of insertions
Name
Expression data
hide Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
hide Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term
Evidence
References
oogenesis
inferred from mutant phenotype
(Perrimon et al., 1984)
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
gene
 
hide Interactions & Pathways
hide Summary of Physical Interactions
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
brc allele
Gene
References
hide External Data
Linkouts
hide Orthologs
hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
hide Human Orthologs (0)
Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 0 )
hide Genomic Clones ( 0 )
hide cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
hide Antibody Information
hide Other Information
hide Discoverer
Fahmy, 1952.
 
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
hide Other Comments
hide External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
hide Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym
brc
 
C93
(Kramers et al., 1991, Schalet, 1986, Kramers et al., 1983)
DCE-12
(Kramers et al., 1991)
l(1)1Db
 
Name Synonym
brachymacrochaetae
 
Secondary FlyBase IDs
hide References ( 14 )
Research paper
Shcherbata et al., 2004, Development 131(13): 3169--3181
The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell-cycle transitions. [FBrf0179442]
Kramers et al., 1991, Mutat. Res. 252: 17--33
Inhalation exposure in Drosophila mutagenesis assays: experiments with aliphatic halogenated hydrocarbons, with emphasis on the genetic activity profile of 1,2-dichloroethane. [FBrf0054740]
Merriam et al., 1991, Science 254(5029): 221--225
Toward cloning and mapping the genome of Drosophila. [FBrf0055071]
Perrimon et al., 1989, Genetics 121: 333--352
Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. [FBrf0049894]
Voelker et al., 1989, Genetics 122: 625--642
Molecular and genetic organization of the suppressor of sable and Minute(1)1B region in Drosophila melanogaster. [FBrf0049919]
Eberl et al., 1988, D. I. S. 67: 36
Determination of lethal phases of mutations in the su(s) microregion. [FBrf0047748]
Lefevre and Watkins, 1986, Genetics 113: 869--895
The question of the total gene number in Drosophila melanogaster. [FBrf0044483]
Schalet, 1986, Mutat. Res. 163: 115--144
The distribution of and complementation relationships between spontaneous X-linked recessive lethal mutations recovered from crossing long-term laboratory stocks of Drosophila melanogaster. [FBrf0045066]
Perrimon et al., 1984, Dev. Biol. 105: 404--414
The effects of zygotic lethal mutations on female germ-line functions in Drosophila. [FBrf0040730]
Kramers et al., 1983, Mutat. Res. 107: 187--201
High proportion of multi-locus deletions among hycanthone-induced X-linked recessive lethals in Drosophila melanogaster. [FBrf0039985]
Maddern, 1972, D. I. S. 49: 40
[Linkage data.] [FBrf0095621]
Lefevre, 1971, Genetics 67: 497--513
Salivary chromosome bands and the frequency of crossing over in Drosophila melanogaster. [FBrf0022754]
Fahmy and Fahmy, 1958, D. I. S. 32: 67--78
[New mutants report.] [FBrf0063418]
Book
Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
The Genome of Drosophila melanogaster. [FBrf0066905]