FB2021_01, released Feb 18, 2021

Gene: Dmel\bur

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General Information
Symbol
Dmel\bur
Species
D. melanogaster
Name
burgundy
Annotation Symbol
CG9242
Feature Type
protein_coding_gene
FlyBase ID
FBgn0000239
Gene Model Status
Current
Stock Availability
19 publicly available
Gene Snapshot
burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. [Date last reviewed: 2019-09-12]
Other Summaries
Also Known As

GMPS, l(2)10523

Key Links
Genomic Location
Cytogenetic map
39A7-39B1
Sequence location
2L:21,174,182..21,179,683 [-]
Recombination map

2-54

RefSeq locus
NT_033779 REGION:21174182..21179683
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables deubiquitinase activator activity
inferred from direct assay
(van der Knaap et al., 2005)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables ATP binding
inferred from electronic annotation with InterPro:IPR001674, InterPro:IPR004739, InterPro:IPR025777
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables GMP synthase activity
inferred from biological aspect of ancestor with PANTHER:PTN000229987
(assigned by GO_Central )
(Gaudet et al., 2011)
enables pyrophosphatase activity
inferred from electronic annotation with InterPro:IPR025777
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (5 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
involved_in axon guidance
inferred from mutant phenotype
(Long et al., 2006)
involved_in histone deubiquitination
inferred from direct assay
(van der Knaap et al., 2005)
involved_in positive regulation of smoothened signaling pathway
inferred from mutant phenotype
(Zhou et al., 2015)
involved_in regulation of ubiquitin-specific protease activity
inferred from direct assay
(van der Knaap et al., 2005)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in GMP biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000229987
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in polytene chromosome
inferred from direct assay
(van der Knaap et al., 2010)
part_of protein-containing complex
inferred from physical interaction with FLYBASE:Usp7; FB:FBgn0030366
(van der Knaap et al., 2005)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in cytosol
inferred from biological aspect of ancestor with PANTHER:PTN000229987
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
CARBON-NITROGEN LIGASES, WITH GLUTAMINE AS AMIDO-N-DONOR -
Carbon-nitrogen ligases, with glutamine as amido-n-donor, catalyze the transfer of the amide nitrogen of glutamine to a variety of substrates.
OTHER PYROPHOSPHATASES -
The OTHER PYROPHOSPHATASES group contains pyrophosphatases that do not fit into any of the other major classes of pyrophosphatases.
Pathway (FlyBase)
Positive Regulators of Hedgehog Signaling Pathway -
Positive regulators of hedgehog signaling up-regulate the pathway, resulting in the activation of transcription of hh-responsive genes.
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
bur: burgundy
Eye color dull, darkish brown (like pr), brilliant orange in combination with cn. burgua supplementable by guanosine but not other ribonucleosides or nucleic acid bases; inosine-5 -monophosphate dehydrogenase activity reduced compared to normal (Johnston, Nash, and Naguib, 1985, Biochem. Genet. 23: 539-55). Classification and viability excellent. Fertility of females good; of males, variable. RK1.
burgua
Recessive auxotroph for guanosine; supplementable by 3.2 mM of guanosine but not by other ribonucleosides or nucleic acid bases. Homozygotes have dark red eyes; this character segregates with the nutritional requirement. Inosine dehydrogenase activity of burgua larval extracts an order of magnitude lower than that of wild type (Johnston, Nash, and Naguib, 1985, Biochem. Genet. 23: 539-55).
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\bur for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Graveley et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
bur-RB
FBtr0301342
NM_138759
2915
683
bur-RC
FBtr0343875
NM_001299191
3116
683
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
bur-PB
FBpp0290556
76.8
683
6.79
NP_620114
AAF53975
bur-PC
FBpp0310411
76.8
683
6.79
NP_001286120
AHN54634
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

683 aa isoforms: bur-PB, bur-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bur using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in polytene chromosome
inferred from direct assay
(van der Knaap et al., 2010)
part_of protein-containing complex
inferred from physical interaction with FLYBASE:Usp7; FB:FBgn0030366
(van der Knaap et al., 2005)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\bur in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 14 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of bur
Transgenic constructs containing regulatory region of bur
Aberrations (Deficiencies and Duplications) ( 8 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\GMPS
13 of 15
Yes
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Gmps
12 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (1)
Rnor\Gmps
9 of 13
Yes
Yes
Xenopus tropicalis (Western clawed frog) (1)
Xtro\gmps
3 of 12
Yes
Yes
Danio rerio (Zebrafish) (1)
Drer\gmps
12 of 15
Yes
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\gmps-1
12 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (2)
Atha\AT1G63660
6 of 9
Yes
Yes
Atha\AT1G70570
1 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\GUA1
11 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\gua2
8 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091903B3 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00001068
Drosophila simulans
Dsim\GD21646
Drosophila sechellia
Dsec\GM23268
Drosophila erecta
Dere\GG21516
Drosophila yakuba
Dyak\GE12995
Drosophila ananassae
Dana\GF15152
Drosophila pseudoobscura pseudoobscura
Dpse\GA21637
Drosophila persimilis
Dper\GL25858
Drosophila willistoni
Dwil\GK21111
Drosophila virilis
Dvir\GJ19601
Drosophila mojavensis
Dmoj\GI17996
Drosophila grimshawi
Dgri\GH10300
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915029N )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17018297
Glossina morsitans
Tsetse fly
Gmor\GMOY007360
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_06586
Mayetiola destructor
Hessian fly
Mdes\Mdes002245
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL001869
Anopheles darlingi
American malaria mosquito
Adar\ADAC000265
Anopheles gambiae
Malaria mosquito
Agam\AGAP010139
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000505
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W022D )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA007436
Danaus plexippus
Monarch butterfly
Dple\DPOGS209487-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL016271
Apis florea
Little honeybee
Aflo\2810244036
Apis mellifera
Western honey bee
Amel\bur
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP23576
Bombus terrestris
Buff-tailed bumblebee
Bter\15210125
Linepithema humile
Argentine ant
Lhum\LH24096
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0017f4
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011390
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_06914
Tribolium castaneum
Red flour beetle
Tcas\TC030725
Pediculus humanus
Human body louse
Phum\PHUM333140
Rhodnius prolixus
Kissing bug
Rpro\RPRC007934
Cimex lectularius
Bed bug
Clec\CLEC000793
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006177
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_07425
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01ZX )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Ixodes scapularis
Black-legged tick
Isca\ISCW018543
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79574.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g06320
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_308688
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G031G )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Gmps
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000005720
Gallus gallus
Domestic chicken
Ggal\GMPS
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    GMPS; guanine monophosphate synthase
    13 of 15
    600358
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Usp7|bur
        enhanceable
        Bre1
        (van der Knaap et al., 2010)
        Usp7|bur
        suppressible
        EcR
        (van der Knaap et al., 2010)
        Usp7|bur
        enhanceable
        EcR
        (van der Knaap et al., 2010)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Pc
        enhanceable
        bur
        (van der Knaap et al., 2005)
        Pc
        suppressible
        bur
        (van der Knaap et al., 2005)
        Rac1
        enhanceable
        bur
        (Long et al., 2006)
        Ras85D|scrib
        suppressible
        bur
        (Willoughby et al., 2013)
        sina
        enhanceable
        bur
        (Neufeld et al., 1998)
        Usp7
        enhanceable
        bur
        (van der Knaap et al., 2010)
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (genetic) - An integrated Molecular Interaction Database
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Positive Regulators of Hedgehog Signaling Pathway -
        Positive regulators of hedgehog signaling up-regulate the pathway, resulting in the activation of transcription of hh-responsive genes.
        Metabolic Pathways
        FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        External Data
        Linkouts
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map

        2-54

        Cytogenetic map
        39A7-39B1
        Sequence location
        2L:21,174,182..21,179,683 [-]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        39A7-39B1
        Limits computationally determined from genome sequence between P{lacW}l(2)k07215k07215&P{lacW}snRNA:U4:39Bk09410 and P{lacW}l(2)k14505k14505&P{lacW}l(2)k05106k05106
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        39B1-39B2
        (determined by in situ hybridisation)
        (Spradling et al., 1999)
        39E-39E
        (Chomey and Nash, 1996)
        39B1-39B2
        (BDGP Project Members, 1994-1999)
        Location determined by an unnamed bur rearrangement suggested to be In(2LR)39E;42B.
        (Chomey and Nash, 1996)
        Experimentally Determined Recombination Data
        Location

        2-54

        (FlyBase, 2016)

        2-54.5

        (Comeron et al., 2012)

        2-

        (Neufeld et al., 1998)

        2-55.7

        (Chomey and Nash, 1996, Meyer and Edmondson, 1949)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (19)
        Genomic Clones (21)
        cDNA Clones (129)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (van der Knaap et al., 2010, van der Knaap et al., 2005)
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of
        Source for database merge of

        Source for merge of: bur l(2)10523

        (Carpenter, 1998.8.17)

        Source for merge of: bur CG9242

        (Strub, 2001.8.10)

        Source for merge of: bur anon-WO0118547.193 anon-WO0118547.204

        (FlyBase, 1996-)
        Additional comments

        snoRNA:bur-a is encoded in an intron of bur.

        (Graveley et al., 2011)

        "CG9242" may correspond to "Scim19". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim19" near/in "CG9241" or "CG9242".

        (Dobie and Karpen, 2001.4.18)

        Source for merge of bur anon-WO0118547.193 anon-WO0118547.204 was sequence comparison ( date:051113 ).

        (FlyBase, 1996-)

        Not allelic to lt, ltd or pr.

        (Meyer and Edmondson, 1949)

        Not allelic to lt, ltd, or pr.

        Other Comments

        bur is required for normal photoreceptor axon guidance in the developing visual system.

        (Long et al., 2006)

        Area matching Drosophila EST AA391495.

        (Davies, 2001.3.15, Davies, 2001.3.15)

        Area matching Drosophila EST AI114266. This EST forms a 1141bp contig with ESTs AA949325, AA735675 and AA391495, and has sequence similarity to GMP synthase genes.

        (Davies, 2001.3.15)

        Area matching Drosophila EST AA439099. This EST forms a 1132bp contig with ESTs AA9493425 and AA940848. ESTs have sequence similarity to GMP synthase genes.

        (Davies, 2001.3.15)

        15 "ES2-2" alleles of bur have been isolated in a screen for dominant modifiers of the sinaGMR.PN eye phenotype.

        (Neufeld et al., 1998)

        Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.

        (Roch et al., 1998)
        Origin and Etymology
        Discoverer
        Etymology
        Identification
        External Crossreferences and Linkouts ( 57 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        MIST (genetic) - An integrated Molecular Interaction Database
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Synonyms and Secondary IDs (15)
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (77)