A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Gene Dmel\c

General Information
SymbolDmel\cSpeciesD. melanogaster
NamecurvedAnnotation symbol
Feature typegeneFlyBase IDFBgn0000245
Created / Updated2006-08-22/2006-08-22
Genomic Location
Chromosome (arm)Recombination map2-75.5
Cytogenetic mapSequence location
hide Summary Information
Automatically generated summary

See sections below for more information
The gene curved is referred to in FlyBase by the symbol c (FBgn0000245). It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotype of these alleles is annotated with wing. It has no annotated transcripts.

hide Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage
c: curved
thumb
c: curved
From Bridges and Morgan, 1919, Carnegie Inst. Washington Publ. No. 278: 165.
Wings thin textured, divergent, uplifted at base, and curved downward throughout their length. RK1.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
52D3-52D7  
Left limit from inclusion within Df(2R)KL69 (FBrf0048246) Right limit from non-inclusion within Df(2R)l30 (FBrf0048246)  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
2-75.5
(Meyer, 1963)
Left of (cM)
(Doane, 1999)
(Doane and Clark, 1984)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
Crossreferences
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Maps to
      Does NOT map to
      Identified with
      hide Mapped Features & Mutations
      Type
      Symbol & Location
      Additional Notes
      References
      hide External Data
      Linkouts
      Crossreferences
      hide Expression Data
      FlyBase-Curated Data
      Transcript and
      Protein data       		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
      hide Summary of Transcript Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Summary of Polypeptide Expression
        Stage
        Tissue/Position
        Reference
        Marker for
          Subcellular Localization
          CV Term
          hide External Data & Images
          Linkouts
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          •
          hide Alleles & Phenotypes
          hide Summary of Allele Phenotypes
          Other Phenotypes
          Allele
          visible | recessive
          visible | dominant
          Phenotype manifest in
          Allele
          wing
          hide Classical Alleles ( 10 )
          For All Classical Alleles Show

          Allele of cClassMutagenStocksKnown lesion
          c1116 --
          c2
            		0 --
            c30 --
            c40 --
            c57e100 --
            c50 --
            c60 --
            c70 --
            cC-K0 --
            cH600 --
            hide Alleles Carried on Transgenic Constructs ( 0 )
            For All Alleles Carried on Transgenic Constructs Show

            Allele of cClassMutagenStocksKnown lesion
            hide Aneuploid Aberrations
            Useful deficiency
             
            Useful duplication
             
            Not disrupted in
            (Oliver et al., 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            Disrupted in
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            (Davis and MacIntyre, 1988)
            hide Transgenic Constructs & Insertions
            Transgenic Constructs
            Type of construct
            Name
            Expression data
            characterization construct
            P{opd-A}
            NA
            P{opd-B}
            NA
            P{w-opd}
            NA
            Insertions
            Type of insertions
            Name
            Expression data
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            Please look at the allele reports for the complete phenotype data
            hide Gene Ontology: Function, Process & Cellular Component ( 0 )
            hide Molecular Function
            CV term
            Evidence
            References
            hide Biological Process
            CV term
            Evidence
            References
            hide Cellular Component
            CV term
            Evidence
            References
            hide Sequence Ontology: Class of Gene
            gene
             
            hide Interactions & Pathways
            hide Summary of Genetic Interactions
            Interacts with
            Please look at the allele data for full details of the genetic interactions
            c allele
            Gene
            References
            hide External Data
            Linkouts
            BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
            •
            hide Orthologs
            Genome-wide drosophilid orthologs
            Curated drosophilid orthologs
            (Sturtevant and Novitski, 1941, Sturtevant and Tan, 1937)
            (Segarra et al., 1995)
            Linkouts
            hide Functional Complementation between Species
            hide Inter-Species Misexpression Data
            Produces phenotype in
            Produces NO phenotype in
            hide Stocks & Reagents
            hide Stocks Listed in FlyBase ( 116 )
            Kyoto
            105814
            c1
            101295
            b1 c1
            101310
            b1 pr1 c1
            105815
            c1 wt1 px1
            108295
            b1 Dp49Fk-1 c1/SM5
            105816
            cg1 c1/In(2LR)U, U1
            Bloomington
            250
            c1
            275
            dke1 c1
            252
            cg1 c1/SM5
            1370
            C(2)EN, c1 bw1
            251
            c1 wt1 px1
            5553
            b1 Dp49Fk-1 c1/SM5
            hide Genomic Clones ( 0 )
            hide cDNA Clones ( 0 )
            cDNA Clones, Fully Sequenced
            BDGP DGC clones
            Other clones
            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
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            Affy Oligo
            Linkouts
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            hide Identification
            hide Position Effect Variegation Data
            hide Relationship to Other Genes
            Source for database identity of
            Source for database merge of
            Additional comments
            hide Comments About Role
            hide Comments About Molecular Function
            hide Other Comments
            hide External Crossreferences & Linkouts
            Sequence Crossreferences
            Other Crossreferences
            Linkouts
            BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
            •
            FLIGHT - Cell culture data for RNAi and other high-throughput technologies
            •
            hide Synonyms & Secondary IDs ( 7 )
            Reported As
            Symbol Synonym
            C
            (Krivshenko, 1956)
            c
             
            mlck
            (Kreuz et al., 2008)
            Strn-mlck
            (Kreuz et al., 2008)
            Name Synonym
            curved
            (Kreuz et al., 2008)
            myosin light chain kinase
            (Kreuz et al., 2008)
            Stretchin-mlck
            (Kreuz et al., 2008)
            Secondary FlyBase IDs
              hide References ( 43 )
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