c3G, crossover suppressor on 3 of Gowan
transverse element of the synaptonemal complex, a meiotic structure that regulates the repair of double-strand breaks (DSBs) into crossovers or gene conversions - required for centromere separation in Pp1-87B RNAi oocytes
Please see the JBrowse view of Dmel\c(3)G for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.41
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\c(3)G using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
c(3)G immunoreactivity becomes concentrated in the pro-oocyte as the germline cyst progresses through early development in the germarium.
c(3)G protein is detected in a ribbon pattern along the length of meiotic chromosomes during pachytene in germarium region 2a of the ovary. Staining persists through stage 7 of oogenesis.
JBrowse - Visual display of RNA-Seq signals
View Dmel\c(3)G in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
monoclonal
c(3)G protein is present in a thread-like pattern along the lengths of chromosomes in meiotic prophase in females, consistent with a role as a synaptonemal complex protein present on meiotic bivalents.
c(3)G is required for recombination and synaptonemal complex assembly.
Source for merge of: c(3)G CG17604