PKA, DC1, PKA C2
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.53
None of the polypeptides share 100% sequence identity.
376, 354 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pka-C2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pka-C2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
When dsRNA constructs are made and transiently transfected into S2 cells in RNAi experiments, a whole range of mitotic abnormalities, spindle abnormalities and chromosome abnormalities are seen.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
One of 11 cAMP-dependent D.melanogaster DNA clones whose sequences are similar to that of Pka-C1 within the kinase domain identified by nucleic acid hybridization. Pka-C2 shows 45% amino acid identity to the corresponding mouse protein kinase