PKA, DC1, PKA C2
Please see the JBrowse view of Dmel\Pka-C2 for information on other features
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Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.53
None of the polypeptides share 100% sequence identity.
376, 354 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pka-C2 using the Feature Mapper tool.
Pka-C2 transcripts are detected in pupae and adults and are more abundant in adult bodies than heads. A slightly smaller transcript is detected in embryos.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Pka-C2 in GBrowse 23-101
3-98.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
When dsRNA constructs are made and transiently transfected into S2 cells in RNAi experiments, a whole range of mitotic abnormalities, spindle abnormalities and chromosome abnormalities are seen.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Isolated from a genomic library using a Pka-C1 probe.
Pka-C2 may encode a protein kinase.
One of 11 cAMP-dependent D.melanogaster DNA clones whose sequences are similar to that of Pka-C1 within the kinase domain identified by nucleic acid hybridization. Pka-C2 shows 45% amino acid identity to the corresponding mouse protein kinase
