Cecropin, CecA, cecropin A, Cec, cecropinA
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CecA2 using the Feature Mapper tool.
Cecropin mRNAs are induced after injection of a bacterial suspension into adult abdomens. They can also be induced by feeding flies bacteria-containing food.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CecA2 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: CecA2 CG1367
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day. Shows alteration in expression in a Clk mutant background.
Genes encoding antibacterial peptides are regulated in a manner distinct from that of Drs, encoding the antifungal peptide. The Cecropins require the spz-cact regulatory cassette for expression at the adult stage.
Transcription is not strongly induced by hymenopteran parasitoids.
One of four structural genes for four very similar cecropin proteins (cecropin A1, A2, B and C), bacteriocidal proteins that are induced in adults in response to bacterial infection. All cecropin genes are coordinately induced by injection of bacteria, although the B gene is expressed at a much lower level. Cecropins also induced by ingested bacteria.