Cecropin, Cec, Cec-C
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Small CecC-derived peptides identified by nano LC-MS/MS: pQAANVAATAR-amide, GIAQQAANVAATAR-amide, DATIQGLGIAQQAANVAATAR-amide.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CecC using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: cyclical, peak ZT21-0
Expressed cyclically in the adult fat body.
JBrowse - Visual display of RNA-Seq signals
View Dmel\CecC in JBrowse3-100
3-97.8
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day. Shows alteration in expression in a Clk mutant background.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
One of four structural genes for four very similar cecropin proteins (cecropin A1, A2, B and C), bacteriocidal proteins that are induced in adults in response to bacterial infection.
Source for merge of: CecC BcDNA:RH33561
Source for merge of CecC BcDNA:RH33561 was a shared cDNA ( date:030728 ).
Source for identity of: CecC CG1373