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Gene Dmel\cl

General Information
Symbol	Dmel\cl	Species	D. melanogaster
Name	clot	Annotation symbol	CG11024
Feature type	protein_coding_gene	FlyBase ID	FBgn0000318
Gene Model Status	Current	Stock availability	55 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	25E5-25E5	Sequence location	2L:5,520,235..5,521,382 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene clot is referred to in FlyBase by the symbol Dmel\cl (CG11024, FBgn0000318). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: disulfide oxidoreductase activity. There is experimental evidence that it is involved in the biological process: eye pigment biosynthetic process. 17 alleles are reported. The phenotypes of these alleles are annotated with: Malpighian tubule; pigment cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF953, thioredoxin-like; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, adult spermathecae, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1623936_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of cl. Gene sequence location is 2L:5520235..5521382.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	cl: clot Eye color dark maroon to sepialike with age, is less extreme than sepia. Severely deficient in one of three enzyme activities required for the conversion of dihydroneopterin triphosphate to pyrimidodiazepine, a precursor of the drosopterins (Wiederrecht, Paton, and Brown, 1984, J. Biol. Chem. 259: 2195-2200). Claimed to accumulate 2-amino-4-hydroxypteridine, biopterin, sepiapterin, and xanthopterin (Nikla, 1972, Can. J. Genet. Cytol. 14: 105-11). Eye color autonomous when larval optic disk is transplanted into wildtype host (Beadle and Ephrussi, 1936, Genetics 21: 230). Larval Malpighian tubes pale yellow, distinguishable from wild type (Brehme and Demerec, 1942, Growth 6: 351-56). RK1.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	Sequence features BKN29215
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25E5-25E5   Limits computationally determined from genome sequence between P{lacW}vrik05901&P{PZ}cype03771 and P{lacW}Hel25Ek11511
Experimentally Determined Cytological Location
Cytogenetic map Notes References 25E1-25E3   (determined by in situ hybridisation)   (Giordano et al., 2003)
Experimentally Determined Recombination Data
Location	2-16.5 (Reuter and Szidonya, 1983, Meyer, 1963) 2-18.83 (Kotarski et al., 1983)
Left of (cM)	Gpdh (Grell, 1967, Kotarski et al., 1983) l(2)26Ae (Kotarski et al., 1983)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\cl for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) cl-RA FBtr0079095  NM_135086   640   126
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein cl-PA   FBpp0078728   14.7   126   5.26     NP_608930   AAF52253
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF953, thioredoxin-like (IPR010357) Thioredoxin-like fold (IPR012336)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695526   AE014134 AAF52253   AF503572 AAN03825   AI110151   AI297337   AI388826   AI404672   AW941183   AY060849 AAL28397   AY113391 AAM29396   AY232193   BE975025   BE977470   BI163608   BI166593   BI355323   BI486084   BI582155   CK657242   CK662099   CO154864   CO155013   CO190361   CO273668   CO276190   CO287649   CO333142   CZ466588   EC071512   EC086006   EC195254   EC217322   EC218292   EC224485   EC230532   EC236781   EC237154   EC261954   EC263159   EC267446   EV584791   EV593054   EV593465   EV598301   GH738793   GH738995   GH739571   GH739632   GH740568   GH741365   GH742161   GH742557   GH744872   GH745323   GH746084   GH746179   GH746691   GH761918   GH762566   GH765043   GH765068   GH765424   GH768072   GH769047
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VMQ9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0000318    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0000318 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0000318 expression level Developmental Stage   Expression Level embryo 00-02hr    13057 embryo 02-04hr    14246 embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1    10460 larva L2    10661 larva L3 12hr old    12274 larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6    12112 larva L3 puffstage 7-9    12351 white prepupae new    10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day    10117 adult male 05day    11854 adult male 30day    11932 adult female 01day    9555 adult female 05day    10202 adult female 30day    11177 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13057) embryo 02-04hr  (14246) embryo 04-06hr  (7597) embryo 06-08hr  (3105) embryo 08-10hr  (3912) embryo 10-12hr  (7513) embryo 12-14hr  (4623) embryo 14-16hr  (5456) embryo 16-18hr  (5417) embryo 18-20hr  (5511) embryo 20-22hr  (6981) embryo 22-24hr  (5931) larva L1  (10460) larva L2  (10661) larva L3 12hr old  (12274) larva L3 puffstage 1-2  (9390) larva L3 puffstage 3-6  (12112) larva L3 puffstage 7-9  (12351) white prepupae new  (10318) white prepupae 12hr  (9326) white prepupae 24hr  (9459) pupae 2d postWPP  (9466) pupae 3d postWPP  (8526) pupae 4d postWPP  (7611) adult male 01day  (10117) adult male 05day  (11854) adult male 30day  (11932) adult female 01day  (9555) adult female 05day  (10202) adult female 30day  (11177) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13057) embryo 02-04hr  (14246) embryo 04-06hr  (7597) embryo 06-08hr  (3105) embryo 08-10hr  (3912) embryo 10-12hr  (7513) embryo 12-14hr  (4623) embryo 14-16hr  (5456) embryo 16-18hr  (5417) embryo 18-20hr  (5511) embryo 20-22hr  (6981) embryo 22-24hr  (5931) larva L1  (10460) larva L2  (10661) larva L3 12hr old  (12274) larva L3 puffstage 1-2  (9390) larva L3 puffstage 3-6  (12112) larva L3 puffstage 7-9  (12351) white prepupae new  (10318) white prepupae 12hr  (9326) white prepupae 24hr  (9459) pupae 2d postWPP  (9466) pupae 3d postWPP  (8526) pupae 4d postWPP  (7611) adult male 01day  (10117) adult male 05day  (11854) adult male 30day  (11932) adult female 01day  (9555) adult female 05day  (10202) adult female 30day  (11177) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (13057) embryo 02-04hr  (14246) embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1  10460 larva L2  10661 larva L3 12hr old  (12274) larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6  (12112) larva L3 puffstage 7-9  (12351) white prepupae new  10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day  10117 adult male 05day  (11854) adult male 30day  (11932) adult female 01day    9555 adult female 05day  10202 adult female 30day  (11177) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13057 embryo 02-04hr    14246 embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1    10460 larva L2    10661 larva L3 12hr old    12274 larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6    12112 larva L3 puffstage 7-9    12351 white prepupae new    10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day    10117 adult male 05day    11854 adult male 30day    11932 adult female 01day    9555 adult female 05day    10202 adult female 30day    11177 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0000318 expression level Developmental Stage   Expression Level embryo 00-02hr    13057 embryo 02-04hr    14246 embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1    10460 larva L2    10661 larva L3 12hr old    12274 larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6    12112 larva L3 puffstage 7-9    12351 white prepupae new    10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day    10117 adult male 05day    11854 adult male 30day    11932 adult female 01day    9555 adult female 05day    10202 adult female 30day    11177 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13057) embryo 02-04hr  (14246) embryo 04-06hr  (7597) embryo 06-08hr  (3105) embryo 08-10hr  (3912) embryo 10-12hr  (7513) embryo 12-14hr  (4623) embryo 14-16hr  (5456) embryo 16-18hr  (5417) embryo 18-20hr  (5511) embryo 20-22hr  (6981) embryo 22-24hr  (5931) larva L1  (10460) larva L2  (10661) larva L3 12hr old  (12274) larva L3 puffstage 1-2  (9390) larva L3 puffstage 3-6  (12112) larva L3 puffstage 7-9  (12351) white prepupae new  (10318) white prepupae 12hr  (9326) white prepupae 24hr  (9459) pupae 2d postWPP  (9466) pupae 3d postWPP  (8526) pupae 4d postWPP  (7611) adult male 01day  (10117) adult male 05day  (11854) adult male 30day  (11932) adult female 01day  (9555) adult female 05day  (10202) adult female 30day  (11177) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13057) embryo 02-04hr  (14246) embryo 04-06hr  (7597) embryo 06-08hr  (3105) embryo 08-10hr  (3912) embryo 10-12hr  (7513) embryo 12-14hr  (4623) embryo 14-16hr  (5456) embryo 16-18hr  (5417) embryo 18-20hr  (5511) embryo 20-22hr  (6981) embryo 22-24hr  (5931) larva L1  (10460) larva L2  (10661) larva L3 12hr old  (12274) larva L3 puffstage 1-2  (9390) larva L3 puffstage 3-6  (12112) larva L3 puffstage 7-9  (12351) white prepupae new  (10318) white prepupae 12hr  (9326) white prepupae 24hr  (9459) pupae 2d postWPP  (9466) pupae 3d postWPP  (8526) pupae 4d postWPP  (7611) adult male 01day  (10117) adult male 05day  (11854) adult male 30day  (11932) adult female 01day  (9555) adult female 05day  (10202) adult female 30day  (11177) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  13057 embryo 02-04hr  14246 embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1  10460 larva L2  10661 larva L3 12hr old  12274 larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6  12112 larva L3 puffstage 7-9  12351 white prepupae new  10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day  10117 adult male 05day  11854 adult male 30day  11932 adult female 01day    9555 adult female 05day  10202 adult female 30day  11177 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13057 embryo 02-04hr    14246 embryo 04-06hr    7597 embryo 06-08hr    3105 embryo 08-10hr    3912 embryo 10-12hr    7513 embryo 12-14hr    4623 embryo 14-16hr    5456 embryo 16-18hr    5417 embryo 18-20hr    5511 embryo 20-22hr    6981 embryo 22-24hr    5931 larva L1    10460 larva L2    10661 larva L3 12hr old    12274 larva L3 puffstage 1-2    9390 larva L3 puffstage 3-6    12112 larva L3 puffstage 7-9    12351 white prepupae new    10318 white prepupae 12hr    9326 white prepupae 24hr    9459 pupae 2d postWPP    9466 pupae 3d postWPP    8526 pupae 4d postWPP    7611 adult male 01day    10117 adult male 05day    11854 adult male 30day    11932 adult female 01day    9555 adult female 05day    10202 adult female 30day    11177 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0000318    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0000318 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, adult spermathecae, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0000318 expression level Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules    2247.4 Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea    1713.975 Larval Carcass    760.725 Adult Head    651 Adult Eye    1544.9 Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop    1765.2 Adult Midgut    1255.1 Adult Hindgut    767.1 Adult Malpighian Tubules    1769.4 Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart    1191.025 Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (625.85) Larval Midgut  (647.8) Larval Hindgut  (947.8) Larval Malpighian Tubules  (2247.4) Larval Fat Body  (707.5) Larval Salivary Gland  (743.7) Larval Trachea  (1713.975) Larval Carcass  (760.725) Adult Head  (651) Adult Eye  (1544.9) Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop  (1765.2) Adult Midgut  (1255.1) Adult Hindgut  (767.1) Adult Malpighian Tubules  (1769.4) Adult Fat Body  518 Adult Salivary Gland  (841.8) Adult Heart  (1191.025) Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary  (589.9) Adult Testis  (785.6) Adult Male Accessory Gland    343.7 Adult Carcass  508.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules  (2247.4) Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea  (1713.975) Larval Carcass    760.725 Adult Head    651 Adult Eye  (1544.9) Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop  (1765.2) Adult Midgut  (1255.1) Adult Hindgut    767.1 Adult Malpighian Tubules  (1769.4) Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart  (1191.025) Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules    2247.4 Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea    1713.975 Larval Carcass    760.725 Adult Head    651 Adult Eye    1544.9 Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop    1765.2 Adult Midgut    1255.1 Adult Hindgut    767.1 Adult Malpighian Tubules    1769.4 Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart    1191.025 Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0000318 expression level Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules    2247.4 Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea    1713.975 Larval Carcass    760.725 Adult Head    651 Adult Eye    1544.9 Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop    1765.2 Adult Midgut    1255.1 Adult Hindgut    767.1 Adult Malpighian Tubules    1769.4 Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart    1191.025 Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  625.85 Larval Midgut  647.8 Larval Hindgut  (947.8) Larval Malpighian Tubules  (2247.4) Larval Fat Body  707.5 Larval Salivary Gland  743.7 Larval Trachea  (1713.975) Larval Carcass  760.725 Adult Head  651 Adult Eye  (1544.9) Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop  (1765.2) Adult Midgut  (1255.1) Adult Hindgut  767.1 Adult Malpighian Tubules  (1769.4) Adult Fat Body  518 Adult Salivary Gland  (841.8) Adult Heart  (1191.025) Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary  589.9 Adult Testis  785.6 Adult Male Accessory Gland    343.7 Adult Carcass  508.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules  (2247.4) Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea  1713.975 Larval Carcass    760.725 Adult Head    651 Adult Eye  1544.9 Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop  (1765.2) Adult Midgut  1255.1 Adult Hindgut    767.1 Adult Malpighian Tubules  (1769.4) Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart  1191.025 Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    625.85 Larval Midgut    647.8 Larval Hindgut    947.8 Larval Malpighian Tubules    2247.4 Larval Fat Body    707.5 Larval Salivary Gland    743.7 Larval Trachea    1713.975 Larval Carcass    760.725 Adult Head    651 Adult Eye    1544.9 Adult Brain    455.7 Adult Thoracic-Abdominal Ganglion    418.2 Adult Crop    1765.2 Adult Midgut    1255.1 Adult Hindgut    767.1 Adult Malpighian Tubules    1769.4 Adult Fat Body    518 Adult Salivary Gland    841.8 Adult Heart    1191.025 Adult VirginFemale Spermatheca    229.1 Adult InseminatedFemale Spermatheca    217.2 Adult Ovary    589.9 Adult Testis    785.6 Adult Male Accessory Gland    343.7 Adult Carcass    508.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    651   NA  Eye    1544.9   NA  Brain    455.7   625.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    418.2   NA  Crop    1765.2   647.8  Midgut    1255.1   947.8  Hindgut    767.1   2247.4  Malpighian Tubules    1769.4   707.5  Fat Body    518   743.7  Salivary Gland    841.8   NA  Heart    1191.025   1713.975  Trachea    NA   NA  VirginFemale Spermatheca    229.1   NA  InseminatedFemale Spermatheca    217.2   NA  Ovary    589.9   NA  Testis    785.6   NA  Male Accessory Gland    343.7   760.725  Carcass    508.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0000318 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11024-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for cl Stages(s) 4-6 Stages(s) 7-8 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable clc00597 viable, with Scer\GAL4pnr-MD237 clGD17048 viable (with cl1) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 cl9d1 viable (with cl2) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 cl9d1 viable (with cl9d1.Δ6) cl1 cl2 viable (with cl9d1.Δ22) cl1 cl2 viable (with cl9d1.Δ76) cl1 cl2 viable (with cl9d1) cl1 cl2 viable (with Df(2L)cl7) cl9d1.Δ22 cl9d1 viable (with Df(2L)cl-h1) cl9d1.Δ22 cl9d1 Sterility Allele fertile clc00597 Other Phenotypes Allele eye color defective cl1 cl2 clH60 clT60 eye color defective (with cl1) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 eye color defective (with cl2) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 eye color defective (with cl9d1.Δ6) cl1 cl2 eye color defective (with cl9d1.Δ22) cl1 cl2 eye color defective (with cl9d1.Δ76) cl1 cl2 eye color defective (with Df(2L)cl7) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 eye color defective (with Df(2L)cl-h1) cl9d1.Δ6 cl9d1.Δ22 cl9d1.Δ76 Phenotype manifest in Allele Malpighian tubule cl1 cl2 pigment cell cl1 cl2 clH60 clT60 pigment cell (with cl1) cl9d1.Δ22 cl9d1.Δ6 cl9d1.Δ76 pigment cell (with cl2) cl9d1.Δ22 cl9d1.Δ6 cl9d1.Δ76 pigment cell (with cl9d1.Δ6) cl1 cl2 pigment cell (with cl9d1.Δ22) cl1 cl2 pigment cell (with cl9d1.Δ76) cl1 cl2 pigment cell (with Df(2L)cl7) cl9d1.Δ22 cl9d1.Δ6 cl9d1.Δ76 pigment cell (with Df(2L)cl-h1) cl9d1.Δ22 cl9d1.Δ6 cl9d1.Δ76
Classical Alleles ( 13 )
For All Classical Alleles Show
Allele of cl Class Mutagen Stocks Known lesion cl1 spontaneous 44 Yes cl4 ethyl methanesulfonate 5 -- cl2 3 Yes clc00597 piggyBac transposase 2 -- clCA1 X ray 1 -- cl3 ethyl methanesulfonate 0 -- cl9d1.Δ22 Delta2-3 0 Yes cl9d1.Δ6 Delta2-3 0 Yes cl9d1.Δ76 Delta2-3 0 Yes cl9d1 P-element activity 0 Yes clH60 X ray 0 -- clT60 X ray 0 -- clunspecified 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of cl Class Mutagen Stocks Known lesion clGD17048 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes clKK109215 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes clGD6660 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes clScer\UAS.cGa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)cl1 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)cl2 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)cl7 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Davis and MacIntyre, 1988, Knipple et al., 1991) Df(2L)cl9d1.Δ6 (Giordano et al., 2003) Df(2L)cl9d1.Δ76 (Giordano et al., 2003) Df(2L)cl-h1 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Eberl et al., 1997) Df(2L)cl-h2 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Eberl et al., 1997) Df(2L)cl-h3 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)cl-h4 (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Eberl et al., 1997) Df(2L)dp-cl-h1 (Szidonya and Reuter, 1988) Df(2L)dp-cl-h2 (Szidonya and Reuter, 1988) Df(2L)dp-cl-h3 (Szidonya and Reuter, 1988) Df(2L)Exel6012 (Ryder, 2004.4.26) Df(2L)GpdhA (Kotarski et al., 1983) Df(2L)sc19-4 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-12 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) In(2L)Scorv17LC158R   Ts(YSt;2Lt)B236+Ts(YSt;2Rt)D222 (Kotarski et al., 1983)
Not disrupted in	Df(2L)dp-h25 (Bryant et al., 1988) Df(2L)dp-h28 (Bryant et al., 1988) Df(2L)ed1 (Reuter and Szidonya, 1983, Bryant et al., 1988) Df(2L)ed2 (Reuter and Szidonya, 1983) Df(2L)M24F11 (Reuter and Szidonya, 1983, Bryant et al., 1988) Df(2L)M24F-B (Reuter and Szidonya, 1983, Bryant et al., 1988) Df(2L)sc19-1 (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) Df(2L)sc19-3 (Bryant et al., 1988) Df(2L)sc19-5 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-6 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-7 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-8 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)tkv2 (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)tkv3 (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Ts(YLt;2Lt)H151+Ts(YSt;2Rt)D222 (Kotarski et al., 1983) Ts(YLt;2Lt)H164+Ts(YSt;2Rt)H151 (Kotarski et al., 1983)
Duplicated in	Dp(2;1)B19 (Bryant et al., 1988)
Not duplicated in	Ts(2Lt;4Lt)b (Morgan, 1947)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6660} NA P{GD17048} NA P{KK109215} NA P{UAS-cl.G} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions blood{}cl1 NA PBac{PB}clc00597 NA insertion of enhancer trap P{PZ}cl9d1 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
eye pigment biosynthetic process inferred from mutant phenotype (Giordano et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
disulfide oxidoreductase activity non-traceable author statement (Peluso, 2002.4.17)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions cl allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68728 DroID - A comprehensive database of gene and protein interactions. • FBgn0000318 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43938
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15144 Dere\GG25076 Dgri\GH10293 Dmoj\GI17989 Dper\GL25848 Dpse\GA10712 Dsec\GM18551 Dsim\GD23345 Dvir\GJ19575 Dwil\GK15089 Dyak\cl
Curated drosophilid orthologs	Dpse\GA10712   Dyak\cl
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012116-PA Aedes aegypti (mosquito) AAEL014064-PA Aedes aegypti (mosquito) AGAP009738-PA Anopheles gambiae (mosquito) XP_395877.1 Apis mellifera (honey bee) XP_001943376.1 Acyrthosiphon pisum (pea aphid) At5g42850.1 Arabidopsis thaliana (wall cress) 86770 Batrachochytrium dendrobatidis (chytrid fungus) 100641 Branchiostoma floridae (lancelet) XP_001895247.1 Brugia malayi (roundworm nematode) BGIBMGA006709-PA Bombyx mori (silk worm) ENSBTAP00000029147 Bos taurus (bovine) CN26965 Caenorhabditis brenneri (small nematode) CBP13824 Caenorhabditis briggsae (nematode) CE27323 Caenorhabditis elegans (worm) ENSCINP00000028605 Ciona intestinalis (sea squirt) CPIJ005830 Culex pipens (mosquito) ENSCPOP00000002623 Cavia porcellus (guinea pig) 173335 Chlamidomonas reinhardtii (green alga) RP01058 Caenorhabditis remanei (nematode) DDB0237688 Dictyostelium discoideum (amoeba) 302246 Daphnia pulex (daphnia) ENSDARP00000075336 Danio rerio (zebra fish) ENSECAP00000022569 Equus caballus (horse) ENSGACP00000014499 Gymnopilus aculeatus (mushroom) ENSGALP00000038086 Gallus gallus (chicken) 186220 Hypsipyla robusta (cedar shoot borer) ENSP00000250101 Homo sapiens (human) 214285 Lottia gigantea (owl limpet) ENSMMUP00000005049 Macaca mulatta (rhesus monkey) ENSMUSP00000021158 Mus musculus (house mouse) 165587 Nematostella vectensis (starlet anemone) XP_001607213.1 Nasonia vitripennis (wasp) ENSOANP00000000735 Ornithorynchus anatinus (platypus) ENSORLP00000005922 Oryzias latipes (japanese killifish) LOC_Os06g21550.1 Oryza sativa (asian rice) PHUM006684-PA Pediculus humanus (human body louse) PP17383 Pristionchus pacificus (nematode) 151861 Physcomitrella patens (moss) ENSPPYP00000008869 Pongo pygmaeus (orangutan) 548701 Populus trichocarpa (black cottonwood) ENSPTRP00000014752 Pan troglodytes (chimpanzee) ENSRNOP00000019574 Rattus norvegicus (norway rat) 4770555 Sorghum bicolor (sorghum) Smp_092500 Schistosoma mansoni (trematode parasite) XP_787642.1 Strongylocentrotus purpuratus (purple sea urchin) 61314 Trichoplax adhaerens (metazoa) XP_967120.2 Tribolium castaneum (red flour beetle) ENSTNIP00000019309 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000003230 Takifugu rubripes (pufferfish Takifugu) 3705.m00159 Tetrahymena thermophila (ciliate protozoa) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17100 NV11733 LH23374 FBgn0067992 FBgn0217094 FBgn0206717 FBgn0194731 FBgn0173458 JGI_V11_302246 FBgn0070768 FBgn0163432 FBgn0140729 FBgn0117774 FBgn0117205 FBgn0092169 CPIJ005830 BGIBMGA006709 ACYPI36980 ACYPI000630 GB11372 GRX3 GRX2 AAEL014064 AAEL012238 AAEL012116 PHUM012680 PHUM098430
Stocks & Reagents
Stocks Listed in FlyBase ( 55 )
Bloomington	261 cl1 291 dw-24E1 cl1/SM5 4902 Gpo-1n322/CyO, cl4 1298 cl1 fy2 nub2 10188 w1118; PBac{PB}clc00597
Harvard	- PBac{PB}clc00597
Kyoto	105818 cl1 101800 cl2 ; T(Y;2)E 107942 Gpo-1n322/CyO, cl4 106270 cl1 fy2 nub2
VDRC	v101458 P{KK109215}VIE-260B v46489 w1118; P{GD17048}v46489/TM3
	More stocks available...
Genomic Clones ( 2 )
	BACR35L07 BACR44J04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 46 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM02967 RE06767
Other clones	yak-ad_CG11024
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH09637 GH19853 GH24466 GM30378 LP11617 LP22067 LP23378 RE03044 RE69457 RH20106
Other clones	bs37g08 bs64d08 Dmel_dig_014429_0704_0983 Dmel_neb_010589_0672_3187 Dmel_neb_013217_0848_2092 Dmel_neb_014059_0674_2571 EK047914 EK066363 EK111808 EK119920 EK305902 EN04937 EN05210 RP01193 RP001004839 RP001006586 RP001006762 RP001010492 RP001015335 RP001018068 RP001019308 RP001019969 RP001020135 RP001021671 RP001027044 RP001034542 RP001035747 RP001036744 RP001038875 RP001040495 RP001045735 RP001050338 RP001054565
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0000318 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43938
Antibody Information
Other Information
Discoverer
	Bridges, 3rd Jan. 1927.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: cl BcDNA:RE06767 (FlyBase, 1996-) Source for merge of: cl CG11024 (FlyBase, 1996-)
Additional comments	Source for merge of cl BcDNA:RE06767 was a shared cDNA (date:030728). (FlyBase, 1996-) Source for merge of cl CG11024 was sequence comparison (date:021108). (FlyBase, 1996-)
Other Comments
	cl is not the structural gene for Sptr. (Ruiz-Vazquez et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135086 RefSeq (Proteins) • NP_608930 DDBJ / EMBL / GenBank • AA695526 AAF52253 AAL28397 AAM29396 AAN03825 AF503572 AW941183 AY060849 AY113391 BI166593 CZ466588 Entrez Gene - A searchable database of RefSeq genes. • 43938 UniProtKB/TrEMBL • Q9VMQ9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF953, thioredoxin-like (IPR010357) Thioredoxin-like fold (IPR012336)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68728 DroID - A comprehensive database of gene and protein interactions. • FBgn0000318 DRSC - Results from RNAi screens. • FBgn0000318 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0000318 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11024-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0000318 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43938 InParanoid A subset of ortholog calls from InParanoid. • AAEL012116-PA Aedes aegypti (mosquito) AAEL014064-PA Aedes aegypti (mosquito) AGAP009738-PA Anopheles gambiae (mosquito) XP_395877.1 Apis mellifera (honey bee) XP_001943376.1 Acyrthosiphon pisum (pea aphid) At5g42850.1 Arabidopsis thaliana (wall cress) 86770 Batrachochytrium dendrobatidis (chytrid fungus) 100641 Branchiostoma floridae (lancelet) XP_001895247.1 Brugia malayi (roundworm nematode) BGIBMGA006709-PA Bombyx mori (silk worm) ENSBTAP00000029147 Bos taurus (bovine) CN26965 Caenorhabditis brenneri (small nematode) CBP13824 Caenorhabditis briggsae (nematode) CE27323 Caenorhabditis elegans (worm) ENSCINP00000028605 Ciona intestinalis (sea squirt) CPIJ005830 Culex pipens (mosquito) ENSCPOP00000002623 Cavia porcellus (guinea pig) 173335 Chlamidomonas reinhardtii (green alga) RP01058 Caenorhabditis remanei (nematode) DDB0237688 Dictyostelium discoideum (amoeba) 302246 Daphnia pulex (daphnia) ENSDARP00000075336 Danio rerio (zebra fish) ENSECAP00000022569 Equus caballus (horse) ENSGACP00000014499 Gymnopilus aculeatus (mushroom) ENSGALP00000038086 Gallus gallus (chicken) 186220 Hypsipyla robusta (cedar shoot borer) ENSP00000250101 Homo sapiens (human) 214285 Lottia gigantea (owl limpet) ENSMMUP00000005049 Macaca mulatta (rhesus monkey) ENSMUSP00000021158 Mus musculus (house mouse) 165587 Nematostella vectensis (starlet anemone) XP_001607213.1 Nasonia vitripennis (wasp) ENSOANP00000000735 Ornithorynchus anatinus (platypus) ENSORLP00000005922 Oryzias latipes (japanese killifish) LOC_Os06g21550.1 Oryza sativa (asian rice) PHUM006684-PA Pediculus humanus (human body louse) PP17383 Pristionchus pacificus (nematode) 151861 Physcomitrella patens (moss) ENSPPYP00000008869 Pongo pygmaeus (orangutan) 548701 Populus trichocarpa (black cottonwood) ENSPTRP00000014752 Pan troglodytes (chimpanzee) ENSRNOP00000019574 Rattus norvegicus (norway rat) 4770555 Sorghum bicolor (sorghum) Smp_092500 Schistosoma mansoni (trematode parasite) XP_787642.1 Strongylocentrotus purpuratus (purple sea urchin) 61314 Trichoplax adhaerens (metazoa) XP_967120.2 Tribolium castaneum (red flour beetle) ENSTNIP00000019309 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000003230 Takifugu rubripes (pufferfish Takifugu) 3705.m00159 Tetrahymena thermophila (ciliate protozoa) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43938 modMine - Data generated by the modENCODE project. • FBgn0000318 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17100 NV11733 LH23374 FBgn0067992 FBgn0217094 FBgn0206717 FBgn0194731 FBgn0173458 JGI_V11_302246 FBgn0070768 FBgn0163432 FBgn0140729 FBgn0117774 FBgn0117205 FBgn0092169 CPIJ005830 BGIBMGA006709 ACYPI36980 ACYPI000630 GB11372 GRX3 GRX2 AAEL014064 AAEL012238 AAEL012116 PHUM012680 PHUM098430
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	BcDNA:RE06767   CG11024 (Keleman et al., 2009.8.5) cl (Svensson and Larsson, 2007)
Name Synonym	clot (Svensson and Larsson, 2007, Rendina et al., 2010)
Secondary FlyBase IDs
	FBgn0031709 FBgn0063070
References ( 44 )
Generate a list of	All references relating to this gene ( 44 )
List References by type	Research paper  ( 26 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Book  ( 2 )
Recent research papers ( 1 )
	Rendina et al., 2010, Genetics 186(1): 167--181 Bap170, a Subunit of the Drosophila PBAP Chromatin Remodeling Complex, Negatively Regulates the EGFR Signaling. [FBrf0211845] Show all research papers ...