s19, s19-1
Please see the JBrowse view of Dmel\Cp19 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
Gene model reviewed during 6.61
0.75 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
173 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cp19 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
The six major chorion bands are dramatically reduced in follicles of Mcm6K1214, mus101K451 and fs(1)A1059K1 mutants. No reduction of major chorion bands is seen in swa6 although some affects are seen in higher molecular weight components.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Cp19 in JBrowse3-26
3-20.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Cp19 is subject to post-transcriptional control at stage 14.
The Cp15, Cp16, Cp18 and Cp19 genes of the chorion cluster have been characterized in D.melanogaster, D.subobscura, D.virilis and D.grimshawi. The temporally specific follicular expression of Cp15, Cp16, Cp18 and Cp19 and gene organization has been conserved. Highly conserved elements exist in the 5' flanking DNA of Cp16 and Cp19.
mus101K451, Mcm6K1214 and fs(1)A1059K1 mutants interfere with the amplification of the major chorion genes Cp15, Cp16, Cp18, Cp19, Cp36 and Cp38.
Sequence analysis of Cp15, Cp18 and Cp19 has led to the identification of a specific DNA element that may control tissue specificity of amplification. Sequences have also been found that may recognize DNA-binding proteins and so function in regulating the amplification or expression of the chorion genes.
The third of four chorion-protein genes in a 6-kb sequence; encodes S19-1, a chorion protein estimated at 19,000 daltons.
The third of four chorion-protein genes in a 6-kb sequence; encodes S19-1, a chorion protein estimated at 17,500 daltons. Electrophoretic variants identified by isoelectric focusing.
