Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cp19 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Cp19 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
The Cp15, Cp16, Cp18 and Cp19 genes of the chorion cluster have been characterized in D.melanogaster, D.subobscura, D.virilis and D.grimshawi. The temporally specific follicular expression of Cp15, Cp16, Cp18 and Cp19 and gene organization has been conserved. Highly conserved elements exist in the 5' flanking DNA of Cp16 and Cp19.
Deletion analysis of the chorion gene cluster using P element mediated transformation has identified a 1.5kb region in the vicinity of Cp15 and Cp19 that is important for high chorion gene amplification levels.
Sequence analysis of Cp15, Cp18 and Cp19 has led to the identification of a specific DNA element that may control tissue specificity of amplification. Sequences have also been found that may recognize DNA-binding proteins and so function in regulating the amplification or expression of the chorion genes.
The third of four chorion-protein genes in a 6-kb sequence; encodes S19-1, a chorion protein estimated at 19,000 daltons.
The third of four chorion-protein genes in a 6-kb sequence; encodes S19-1, a chorion protein estimated at 17,500 daltons. Electrophoretic variants identified by isoelectric focusing.