Gene model reviewed during 5.45
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cp38 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Cp38 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Primarily regulated at the transcriptional level.
Transcription termination sites of Cp36 and Cp38 have been mapped using EM analysis. Results demonstrate that Cp36 and Cp38 terminate more closely to the poly(A) addition sites and in a shorter region than many other polyadenylation genes examined to date.
Tissue and stage specific expression of Cp15 and Cp38 are retained when the genes are removed from the remaining genes of the cluster, and in the absence of amplification. Deletion analysis has delimited sequences regulating Cp38 transcription to within a portion of its upstream spacer and 5' transcribed region.
Structural gene for s38-1, a 38,000-dalton chorion protein. Synthesis primarily during stages 12 and 13 (Waring and Mahowald) and during stages 11 and 12 (Petri, Wyman and Kafatos, 1976). 2,000 to 3,000 daltons cleaved from primary translation product to yield mature protein (Spradling, Digan, Mahowald, Scott and Craig, 1980). Temporal and spatial distribution of expression described by Parks and Spradling (1987).