ATF4, l(2)crc, dATF4, ATF-4
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.45
Gene model reviewed during 6.13
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\crc using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\crc in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
One or more of the processed transcripts for these genes contain several non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG46314 (FBgn0284230) and CG8669 (FBgn0000370).
Source for merge of crc CG8669 was sequence comparison ( date:000526 ).
Host gene for maternally inherited stable intronic sequence RNA (sisRNA).
Changes in expression profiles associated with the unfolded protein response have been analyzed in S2 cells following treatment with dsRNA made from templates generated with primers directed against this gene.
crc is a complex genetic locus with two overlapping lethal complementation groups.
Studies of chitin deposition in the pupal cuticle give no evidence to suggest that crc causes an increase in chitin deposition in the pupal cuticle.