zw9, l(1)zw9, zw-9, sa, EG:95B7.2
Gene model reviewed during 5.50
693 (aa); 110 (kD observed); 75 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\crm using the Feature Mapper tool.
crm protein is ubiquitously expressed throughout development. Expression is strong in nuclei during nuclear multiplication and cellularization and in pole cells. Later in embryogenesis, strong staining is observed in the CNS and the gonads. In third instar larvae, strong staining is observed in polytene nuclei of salivary glands. crm protein and mus209 protein display overlapping expression patterns during embryogenesis and appear to co-localize in polytene nuclei.
GBrowse - Visual display of RNA-Seq signalsView Dmel\crm in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: crm CG2714
l(1)zw9, sa: sparse arista and swa: swollen antennae. These are now designated alleles of crm.
Mutants exhibit typical Pc-group phenotypes, including homeotic transformations and modification of PEV.
l(1)zw9 is synonymous with sa.
Antennae swollen, aristae short and branches fewer than in wild type. Wings slightly divergent and in some alleles nicked. Males have small extra sex combs on second tarsal segment of prothoracic legs and less frequently on basitarsal segments of mesothoracic and rarely metathoracic legs. crmsa;Pc/+ males have large sex combs on all six basitarsi and small sex combs on all second tarsal segments in many flies. One or both postverticals lacking and other bristles occasionally missing or doubled. Body slightly darkened. Fertility of both males and females reduced, females more severely than males. Strength of sterilizing effect allele-dependent. Females generally sterile.