yok, l(1)2, EG:30B8.1 , yolky, l30
Gene model reviewed during 5.51
There is only one protein coding transcript and one polypeptide associated with this gene
Colocalizes with a complex containing snRNP proteins.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\crn using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\crn in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells.
Muscle phenotype of mutants studied using polarised light microscopy and antibody staining to detect Mhc-lacZ reporter gene expression in muscles.
Molecular analysis of crn indicates it is related to a family of genes required for normal progression through the cell cycle. Sequence similarity and mutant phenotype suggest crn encodes a protein required for cell division. Zygotic expression of crn is required to complete late rounds of cell division in the embryonic nervous system.
A screen for X-linked genes that affect embryo morphology revealed yok.
A saturation analysis of the 2D3--2F5 region detected the crn complementation group.
Germline clonal analysis indicates that this locus is required for female germ line viability.