Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pkg21D using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pkg21D in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Pkg21D CG3324
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Genes in D.melanogaster encoding products related (by sequence comparison) to cGMP-dependent protein kinases of mammals have been isolated by using a Drosophila cAMP-dependent protein kinase catalytic subunit gene as a probe.
Encodes a product with putative cGMP-dependent binding and kinase domains that is 14% larger than the corresponding mammalian enzyme. It is believed to bind cGMP and to undergo changes enabling its catalytic site to interact with appropriate substrates. This gene is unusually polymorphic in various Drosophila stocks.