DipB
Please see the JBrowse view of Dmel\Dip-B for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.55
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.54
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dip-B using the Feature Mapper tool.
Comment: maternally deposited
Dip-B is present atfairly uniform specific activities throughout development. Specificactivity is highest in pupae and lowest in feeding stages. Dip-Bspecific activity was also found to be fairly uniform in all tissuesstudied except in gut and Malphigian tubules where it is higher thanaverage and adult thorax where it is low.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Dip-B in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Dip-B CG9285
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; decreased expression in per01, tim01 and increased expression in ClkJrk background.
A screen to identify modifiers for the dipeptidase locates them on the X, second and third chromosomes.
Larvae of genetically different lines were reared under varying levels of osmotic stress to study the genetic basis of the correlation of peptidase activities in response to environmental challenge.
The developmental variation and tissue locations of Dip-A and Dip-B are determined.
Examination of D.melanogaster lines revealed genetic variation of Dip-A and Dip-B within sets of lines that only differed in the second or third chromosome. Experiments were undertaken to identify the types of activity modifiers that may be polymorphic in natural populations and to characterize the genetic organization of the modifiers.
Dip-B activity is high in postembryonic stages, the activity in the adult is proportional to gene dosage.
Structural gene for dipeptidase B (DIP-B), which is virtually monomorphic in natural populations but which differs in electrophoretic mobility from dipeptidase-B variants in D.simulans. Substrate specificities determined (Laurie-Ahlberg, 1982).
