ecd1, l(3)ecd, ecd-1, l(3)62Db
physically interacts with several components of the U5 snRPN pre-mRNA splicing complex - mutants disrupt production of the steroid hormone ecdysone causing developmental and reproductive defects - loss of function results in intron retention within , accounting for ecdysone deficiency in mutants
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Antibody raised to amino acids 270-429
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ecd using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ecd in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: ecd CG5714
The ecdysone pathway is required for proliferation and differentiation of hematopoietic precursors of lamellocytes and crystal cells.
ecd is required for progression of the morphogenetic furrow in the eye imaginal disc.
Analysis of the incorporation of <up>3H</up>C, <up>3H</up>25C and <up>3H</up>7d25C into ecdysteroids by the larval ring glands and adult ovaries to help understand the basis of lack of normal ecdysteroidogenesis in mutants of ecd.
An investigation of the relationship between transcription, puffing and hormone regulation of intermoult puff was analysed using ecd1 mutant embryos.
A temperature sensitive ecdysdone deficient mutation provides a useful tool for examining hormonal control (hormone 20-hydroxyecdysone) of specific gene-enzyme systems during development.
The prepupal peak of Argk gene product activity is regulated by the hormone 20-hydroxyecdysone.