FB2020_06, released Dec 22, 2020
Gene: Dmel\Edg78E
FB2020_06, released Dec 22, 2020
Gene: Dmel\Edg78E
Gene: Dmel\Edg78E
Gene: Dmel\Edg78E
EDG78
Please see the JBrowse view of Dmel\Edg78E for information on other features
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Gene model reviewed during 5.45
Gene model reviewed during 5.54
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Edg78E using the Feature Mapper tool.
Edg78E transcripts are present in equal abundance in imaginal and larval epidermis. Transcripts are detected in 8hr pupae and reach maximal accumulation in 10hr prepupae. None are detectable in 0-6hr prepupae or 14hr pupae.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Edg78E in GBrowse 23-47
3-47
3-43.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Temporal profile of gene expression is altered in Eip74EF mutant background.
Ecdysteroid-regulated gene.
Initial characterization of Edg78E suggests the gene encodes a cuticle protein.
The spatial and temporal expression is as expected for genes that encode pupal cuticle proteins.
mRNA on Northerns: 0.6 kb Identification: Differential screen of a genomic library with cDNA isolated from imaginal discs pulsed with 20-hydroxyecdysone, 20-HE (Fechtel, Natzle, Brown and Fristrom, 1988). Transcripts in imaginal disc tissue, beginning at six to nine hours, following a six-hour 20-HE pulse, but not in the absence or continual presence of 20-HE; mRNA's enriched in membrane-bound polysome fractions of imaginal discs. Translation product from hybrid selected mRNA of Edg78E reacts with polyclonal antibodies prepared against purified pupal cuticle proteins.
