EDG84, cc1, EDG-84, EDG-84A
Please see the JBrowse view of Dmel\Edg84A for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
Gene model reviewed during 6.02
There is only one protein coding transcript and one polypeptide associated with this gene
188 (aa); 18.2 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Edg84A using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Edg84A transcripts are detected only in imaginal epidermis. They are detected in 8hr prepupae and reach maximal accumulation in 10hr prepupae. No transcripts are detected in 0-6hr prepupae or 14hr pupae.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Edg84A in JBrowse3-48
3-44.2
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Temporal profile of gene expression is altered in Eip74EF mutant background.
Ecdysteroid-regulated gene.
Initial characterization of Edg84A suggests the gene encodes a cuticle protein.
Gene expression is limited to the imaginal epidermis. The spatial and temporal expression is as expected for genes that encode pupal cuticle proteins.
mRNA on Northerns: 0.9 kb Identification: Differential screen of a genomic library with cDNA isolated from imaginal discs pulsed with 20-hydroxyecdysone, 20-HE (Fechtel, Natzle, Brown and Fristrom, 1988). Transcripts in imaginal disc tissue, beginning at six to nine hours, following a six-hour 20-HE pulse, but not in the absence or continual presence of 20-HE; mRNA's enriched in membrane-bound polysome fractions of imaginal discs.
Source for merge of: Edg84A cc1
Source for identity of: Edg84A CG2345