EDG84, EDG-84, EDG-84A, cc1
Gene model reviewed during 5.50
Gene model reviewed during 6.02
There is only one protein coding transcript and one polypeptide associated with this gene
188 (aa); 18.2 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Edg84A using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Edg84A in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Temporal profile of gene expression is altered in Eip74EF mutant background.
The homologs of Antp, ftz, Scr, Dfd, Ama, bcd, zen, pb and lab, but not zen2 are all present in D.pseudoobscura.pseudoobscura, in the same linear order and similarly spaced along the chromosome as in D.melanogaster.
Initial characterization of Edg84A suggests the gene encodes a cuticle protein.
Gene expression is limited to the imaginal epidermis. The spatial and temporal expression is as expected for genes that encode pupal cuticle proteins.
mRNA on Northerns: 0.9 kb Identification: Differential screen of a genomic library with cDNA isolated from imaginal discs pulsed with 20-hydroxyecdysone, 20-HE (Fechtel, Natzle, Brown and Fristrom, 1988). Transcripts in imaginal disc tissue, beginning at six to nine hours, following a six-hour 20-HE pulse, but not in the absence or continual presence of 20-HE; mRNA's enriched in membrane-bound polysome fractions of imaginal discs.