The gene Elongation factor 2b is referred to in FlyBase by the symbol Dmel\Ef2b (CG2238, FBgn0000559). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation elongation factor activity. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Elongation factor G/III/V; Protein synthesis factor, GTP-binding; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Small GTP-binding protein domain; Translation elongation factor EFG/EF2, C-terminal; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation/initiation factor/Ribosomal, beta-barrel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625150_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of Ef2b. Gene sequence location is 2L:21678097..21682150.
Phenotypic Description from the Red Book (Lindsley
& Zimm 1992)
Gene/Allele symbols may differ
from current usage
Ef2
Encodes elongation factor 2 (EF2), which catalyzes
the GTP-dependent translocation of tRNA from the aminoacyl to
the peptidyl site of the ribosome; also catalyzes hydrolysis
of GTP. Expression becomes detectable by four hours of
development and persists into adulthood.
Recent Updates
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modENCODE Temporal Expression Data for FBgn0000559
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.
[download data (TSV)]
Guide to modENCODE expression level colors
No expression (0 - 0)
Extremely low expression (1 - 10)
Very low expression (11 - 100)
Low expression (101 - 400)
Moderate expression (401 - 1400)
Moderately high expression (1401 - 4000)
High expression (4001 - 10000)
Very high expression (10001 - 100000)
Extremely high expression (100001 - 2000000)
Linear, scaled to maximum FBgn0000559 expression level
Developmental Stage
Expression Level
embryo 00-02hr
154692
embryo 02-04hr
245526
embryo 04-06hr
270367
embryo 06-08hr
219958
embryo 08-10hr
228509
embryo 10-12hr
212657
embryo 12-14hr
172395
embryo 14-16hr
204135
embryo 16-18hr
179054
embryo 18-20hr
153577
embryo 20-22hr
163333
embryo 22-24hr
165323
larva L1
221696
larva L2
197396
larva L3 12hr old
166304
larva L3 puffstage 1-2
120642
larva L3 puffstage 3-6
123393
larva L3 puffstage 7-9
131497
white prepupae new
122262
white prepupae 12hr
105426
white prepupae 24hr
111190
pupae 2d postWPP
80126
pupae 3d postWPP
71480
pupae 4d postWPP
87088
adult male 01day
89045
adult male 05day
86936
adult male 30day
85080
adult female 01day
181726
adult female 05day
169457
adult female 30day
168680
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
154692
embryo 02-04hr
245526
embryo 04-06hr
270367
embryo 06-08hr
219958
embryo 08-10hr
228509
embryo 10-12hr
212657
embryo 12-14hr
172395
embryo 14-16hr
204135
embryo 16-18hr
179054
embryo 18-20hr
153577
embryo 20-22hr
163333
embryo 22-24hr
165323
larva L1
221696
larva L2
197396
larva L3 12hr old
166304
larva L3 puffstage 1-2
120642
larva L3 puffstage 3-6
123393
larva L3 puffstage 7-9
131497
white prepupae new
122262
white prepupae 12hr
105426
white prepupae 24hr
111190
pupae 2d postWPP
80126
pupae 3d postWPP
71480
pupae 4d postWPP
87088
adult male 01day
89045
adult male 05day
86936
adult male 30day
85080
adult female 01day
181726
adult female 05day
169457
adult female 30day
168680
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to maximum FBgn0000559 expression level
Developmental Stage
Expression Level
embryo 00-02hr
154692
embryo 02-04hr
245526
embryo 04-06hr
270367
embryo 06-08hr
219958
embryo 08-10hr
228509
embryo 10-12hr
212657
embryo 12-14hr
172395
embryo 14-16hr
204135
embryo 16-18hr
179054
embryo 18-20hr
153577
embryo 20-22hr
163333
embryo 22-24hr
165323
larva L1
221696
larva L2
197396
larva L3 12hr old
166304
larva L3 puffstage 1-2
120642
larva L3 puffstage 3-6
123393
larva L3 puffstage 7-9
131497
white prepupae new
122262
white prepupae 12hr
105426
white prepupae 24hr
111190
pupae 2d postWPP
80126
pupae 3d postWPP
71480
pupae 4d postWPP
87088
adult male 01day
89045
adult male 05day
86936
adult male 30day
85080
adult female 01day
181726
adult female 05day
169457
adult female 30day
168680
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
(154692)
embryo 02-04hr
(245526)
embryo 04-06hr
(270367)
embryo 06-08hr
(219958)
embryo 08-10hr
(228509)
embryo 10-12hr
(212657)
embryo 12-14hr
(172395)
embryo 14-16hr
(204135)
embryo 16-18hr
(179054)
embryo 18-20hr
(153577)
embryo 20-22hr
(163333)
embryo 22-24hr
(165323)
larva L1
(221696)
larva L2
(197396)
larva L3 12hr old
(166304)
larva L3 puffstage 1-2
(120642)
larva L3 puffstage 3-6
(123393)
larva L3 puffstage 7-9
(131497)
white prepupae new
(122262)
white prepupae 12hr
(105426)
white prepupae 24hr
(111190)
pupae 2d postWPP
(80126)
pupae 3d postWPP
(71480)
pupae 4d postWPP
(87088)
adult male 01day
(89045)
adult male 05day
(86936)
adult male 30day
(85080)
adult female 01day
(181726)
adult female 05day
(169457)
adult female 30day
(168680)
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
154692
embryo 02-04hr
245526
embryo 04-06hr
270367
embryo 06-08hr
219958
embryo 08-10hr
228509
embryo 10-12hr
212657
embryo 12-14hr
172395
embryo 14-16hr
204135
embryo 16-18hr
179054
embryo 18-20hr
153577
embryo 20-22hr
163333
embryo 22-24hr
165323
larva L1
221696
larva L2
197396
larva L3 12hr old
166304
larva L3 puffstage 1-2
120642
larva L3 puffstage 3-6
123393
larva L3 puffstage 7-9
131497
white prepupae new
122262
white prepupae 12hr
105426
white prepupae 24hr
111190
pupae 2d postWPP
80126
pupae 3d postWPP
71480
pupae 4d postWPP
87088
adult male 01day
89045
adult male 05day
86936
adult male 30day
85080
adult female 01day
181726
adult female 05day
169457
adult female 30day
168680
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
FlyAtlas Anatomical Expression Data for FBgn0000559
Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]
Guide to FlyAtlas expression level colors
No expression (0 - 9.999)
Low expression (10 - 99.999)
Moderate expression (100 - 499.999)
High level expression (500 - 999.999)
Very high expression (1000 - 25000)
Linear, scaled to maximum FBgn0000559 expression level
Tissue
Expression Level
Larval Central Nervous System
2467.15
Larval Midgut
4652
Larval Hindgut
4247.9
Larval Malpighian Tubules
5413.6
Larval Fat Body
7034
Larval Salivary Gland
6694.6
Larval Trachea
5555.975
Larval Carcass
4600.25
Adult Head
4261.5
Adult Eye
5758.95
Adult Brain
2796.7
Adult Thoracic-Abdominal Ganglion
4229.2
Adult Crop
5850.2
Adult Midgut
4620.8
Adult Hindgut
4798.4
Adult Malpighian Tubules
6217.5
Adult Fat Body
5097.1
Adult Salivary Gland
13984.6
Adult Heart
5730.925
Adult VirginFemale Spermatheca
5165.8
Adult InseminatedFemale Spermatheca
5308.2
Adult Ovary
3193.4
Adult Testis
1442.9
Adult Male Accessory Gland
9555.9
Adult Carcass
5706.2
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(2467.15)
Larval Midgut
(4652)
Larval Hindgut
(4247.9)
Larval Malpighian Tubules
(5413.6)
Larval Fat Body
(7034)
Larval Salivary Gland
(6694.6)
Larval Trachea
(5555.975)
Larval Carcass
(4600.25)
Adult Head
(4261.5)
Adult Eye
(5758.95)
Adult Brain
(2796.7)
Adult Thoracic-Abdominal Ganglion
(4229.2)
Adult Crop
(5850.2)
Adult Midgut
(4620.8)
Adult Hindgut
(4798.4)
Adult Malpighian Tubules
(6217.5)
Adult Fat Body
(5097.1)
Adult Salivary Gland
(13984.6)
Adult Heart
(5730.925)
Adult VirginFemale Spermatheca
(5165.8)
Adult InseminatedFemale Spermatheca
(5308.2)
Adult Ovary
(3193.4)
Adult Testis
(1442.9)
Adult Male Accessory Gland
(9555.9)
Adult Carcass
(5706.2)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
(2467.15)
Larval Midgut
(4652)
Larval Hindgut
(4247.9)
Larval Malpighian Tubules
(5413.6)
Larval Fat Body
(7034)
Larval Salivary Gland
(6694.6)
Larval Trachea
(5555.975)
Larval Carcass
(4600.25)
Adult Head
(4261.5)
Adult Eye
(5758.95)
Adult Brain
(2796.7)
Adult Thoracic-Abdominal Ganglion
(4229.2)
Adult Crop
(5850.2)
Adult Midgut
(4620.8)
Adult Hindgut
(4798.4)
Adult Malpighian Tubules
(6217.5)
Adult Fat Body
(5097.1)
Adult Salivary Gland
(13984.6)
Adult Heart
(5730.925)
Adult VirginFemale Spermatheca
(5165.8)
Adult InseminatedFemale Spermatheca
(5308.2)
Adult Ovary
(3193.4)
Adult Testis
(1442.9)
Adult Male Accessory Gland
(9555.9)
Adult Carcass
(5706.2)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2467.15
Larval Midgut
4652
Larval Hindgut
4247.9
Larval Malpighian Tubules
5413.6
Larval Fat Body
7034
Larval Salivary Gland
6694.6
Larval Trachea
5555.975
Larval Carcass
4600.25
Adult Head
4261.5
Adult Eye
5758.95
Adult Brain
2796.7
Adult Thoracic-Abdominal Ganglion
4229.2
Adult Crop
5850.2
Adult Midgut
4620.8
Adult Hindgut
4798.4
Adult Malpighian Tubules
6217.5
Adult Fat Body
5097.1
Adult Salivary Gland
13984.6
Adult Heart
5730.925
Adult VirginFemale Spermatheca
5165.8
Adult InseminatedFemale Spermatheca
5308.2
Adult Ovary
3193.4
Adult Testis
1442.9
Adult Male Accessory Gland
9555.9
Adult Carcass
5706.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to maximum FBgn0000559 expression level
Tissue
Expression Level
Larval Central Nervous System
2467.15
Larval Midgut
4652
Larval Hindgut
4247.9
Larval Malpighian Tubules
5413.6
Larval Fat Body
7034
Larval Salivary Gland
6694.6
Larval Trachea
5555.975
Larval Carcass
4600.25
Adult Head
4261.5
Adult Eye
5758.95
Adult Brain
2796.7
Adult Thoracic-Abdominal Ganglion
4229.2
Adult Crop
5850.2
Adult Midgut
4620.8
Adult Hindgut
4798.4
Adult Malpighian Tubules
6217.5
Adult Fat Body
5097.1
Adult Salivary Gland
13984.6
Adult Heart
5730.925
Adult VirginFemale Spermatheca
5165.8
Adult InseminatedFemale Spermatheca
5308.2
Adult Ovary
3193.4
Adult Testis
1442.9
Adult Male Accessory Gland
9555.9
Adult Carcass
5706.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(2467.15)
Larval Midgut
(4652)
Larval Hindgut
(4247.9)
Larval Malpighian Tubules
(5413.6)
Larval Fat Body
(7034)
Larval Salivary Gland
(6694.6)
Larval Trachea
(5555.975)
Larval Carcass
(4600.25)
Adult Head
(4261.5)
Adult Eye
(5758.95)
Adult Brain
(2796.7)
Adult Thoracic-Abdominal Ganglion
(4229.2)
Adult Crop
(5850.2)
Adult Midgut
(4620.8)
Adult Hindgut
(4798.4)
Adult Malpighian Tubules
(6217.5)
Adult Fat Body
(5097.1)
Adult Salivary Gland
(13984.6)
Adult Heart
(5730.925)
Adult VirginFemale Spermatheca
(5165.8)
Adult InseminatedFemale Spermatheca
(5308.2)
Adult Ovary
(3193.4)
Adult Testis
(1442.9)
Adult Male Accessory Gland
(9555.9)
Adult Carcass
(5706.2)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
(2467.15)
Larval Midgut
(4652)
Larval Hindgut
(4247.9)
Larval Malpighian Tubules
(5413.6)
Larval Fat Body
(7034)
Larval Salivary Gland
(6694.6)
Larval Trachea
(5555.975)
Larval Carcass
(4600.25)
Adult Head
(4261.5)
Adult Eye
(5758.95)
Adult Brain
(2796.7)
Adult Thoracic-Abdominal Ganglion
(4229.2)
Adult Crop
(5850.2)
Adult Midgut
(4620.8)
Adult Hindgut
(4798.4)
Adult Malpighian Tubules
(6217.5)
Adult Fat Body
(5097.1)
Adult Salivary Gland
(13984.6)
Adult Heart
(5730.925)
Adult VirginFemale Spermatheca
(5165.8)
Adult InseminatedFemale Spermatheca
(5308.2)
Adult Ovary
(3193.4)
Adult Testis
1442.9
Adult Male Accessory Gland
(9555.9)
Adult Carcass
(5706.2)
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
2467.15
Larval Midgut
4652
Larval Hindgut
4247.9
Larval Malpighian Tubules
5413.6
Larval Fat Body
7034
Larval Salivary Gland
6694.6
Larval Trachea
5555.975
Larval Carcass
4600.25
Adult Head
4261.5
Adult Eye
5758.95
Adult Brain
2796.7
Adult Thoracic-Abdominal Ganglion
4229.2
Adult Crop
5850.2
Adult Midgut
4620.8
Adult Hindgut
4798.4
Adult Malpighian Tubules
6217.5
Adult Fat Body
5097.1
Adult Salivary Gland
13984.6
Adult Heart
5730.925
Adult VirginFemale Spermatheca
5165.8
Adult InseminatedFemale Spermatheca
5308.2
Adult Ovary
3193.4
Adult Testis
1442.9
Adult Male Accessory Gland
9555.9
Adult Carcass
5706.2
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 2279 )
Please Note
This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see GBrowse for alignment of the cDNAs and ESTs
to the gene model.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Encodes elongation factor 2 (EF2), which catalyzes the GTP-dependent translocation of tRNA from the aminoacyl to the peptidyl site of the ribosome; also catalyzes hydrolysis of GTP. Expression becomes detectable by four hours of development and persists into adulthood.