egon, egl, spy
Gene model reviewed during 5.45
2.2, 1.9 (compiled cDNA)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eg using the Feature Mapper tool.
During stage 11-12 of embryogenesis, eg transcript is expressed in a subset of neuroblasts in the CNS. In neuroblasts NB2-4, NB3-3, and NB7-3, eg expression is strongest early, and during neuroblast delamination. Weak staining is also seen in some early progeny of neuroblast NB7-3 during stages 11-12. eg expression is not detected at or after stage 13.
In embryo, expressed in small number of CNS neuroblasts, starting late stage 10 or early 11 and observed through stage 12; in stage 14, expression observed in the dorsal sac.
GBrowse - Visual display of RNA-Seq signalsView Dmel\eg in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: eg egon
Mutant allele fails to complement a QTL affecting male mating behaviour.
Loss of function eg mutations produce an unusual differential phenotype with respect to the sister serotonin cells. Hypomorphic alleles can produce viable adults that have a dramatic reduction in the number of serotonin-producing neurons.
Evolutionary history for nuclear receptor genes, in which gene duplication events and swapping between domains of different origins took place, is studied.
Mutant individuals display spread wings.
Egon first isolated from genomic library using a kni zinc-finger probe. Expression detected in embryonic gonad but not in other tissues or at other stages of development.