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Gene Dmel\Eno

General Information
Symbol	Dmel\Eno	Species	D. melanogaster
Name	Enolase	Annotation symbol	CG17654
Feature type	protein_coding_gene	FlyBase ID	FBgn0000579
Gene Model Status	Current	Stock availability	16 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	22B1-22B1	Sequence location	2L:1,724,768..1,729,636 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Enolase is referred to in FlyBase by the symbol Dmel\Eno (CG17654, FBgn0000579). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphopyruvate hydratase activity. It is reported to be involved in the biological process: glycolysis. 19 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Enolase; Enolase, C-terminal; Enolase, N-terminal; Enolase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634065_s_at completely aligns to an exonic region common to each of the 6 FlyBase-annotated transcript isoforms of Eno. Gene sequence location is 2L:1724768..1729636.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Eno: Enolase Structural gene for enolase [2-phospho-D-glycerate hydrolase (EC 4.2.1.11)].
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 22B1-22B1   Limits computationally determined from genome sequence between P{PZ}l(2)0411104111 and P{lacW}CG17646k11021
Experimentally Determined Cytological Location
Cytogenetic map Notes References 22A-22A   (determined by in situ hybridisation)   (Bishop and Corces, 1990)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Eno for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Eno-RA FBtr0077909  NM_058073   1754   433 Eno-RB FBtr0077905  NM_164431   2183   500 Eno-RC FBtr0077907  NM_164432   2257   500 Eno-RD FBtr0077908  NM_164433   2198   500 Eno-RE FBtr0077906  NM_164434   2664   500 Eno-RF FBtr0302115  NM_001169382   2561   433
Additional Transcript Data & Comments
Reported size (kB)	1.3 (sequence analysis) (Bishop and Corces, 1990)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Eno-PA   FBpp0077575   46.7   433   6.52     NP_477421   AAN10458 Eno-PB   FBpp0077571   54.3   500   8.85     NP_722721   AAN10455 Eno-PC   FBpp0077573   54.3   500   8.85     NP_722722   AAN10456 Eno-PD   FBpp0077574   54.3   500   8.85     NP_722723   AAN10457 Eno-PE   FBpp0077572   54.3   500   8.85     NP_722724   AAF51344 Eno-PF   FBpp0291325   46.7   433   6.52     NP_001162853   ACZ94145
Additional Polypeptide Data & Comments
Reported size (kDa)	433 (aa); 46.563 (kD predicted) (Bishop and Corces, 1990)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Enolase (IPR000941) Enolase, conserved site (IPR020809) Enolase, C-terminal (IPR020810) Enolase, N-terminal (IPR020811)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246284   AA263798   AA440082   AA440600   AA440644   AA536400   AA539337   AA539455   AA539796   AA540531   AA694666   AA695764   AA697055   AA697277   AA697821   AA697865   AA699097   AA736150   AA817105   AA950530   AA951480   AA951864   AE014134 AAF51344   AE014134 AAN10455   AE014134 AAN10456   AE014134 AAN10457   AE014134 AAN10458   AC003945   AC004442   AE014134 ACZ94145   AI062625   AI062656   AI062710   AI062780   AI063899   AI064595   AI106620   AI106711   AI107260   AI108108   AI108126   AI108180   AI108199   AI109909   AI110150   AI113534   AI113598   AI113858   AI134061   AI134268   AI134841   AI135157   AI135249   AI238737   AI258438   AI259874   AI260940   AI293312   AI293445   AI295206   AI295353   AI295704   AI296657   AI297172   AI387008   AI387066   AI387274   AI387910   AI388023   AI388041   AI388666   AI388966   AI389168   AI389286   AI389520   AI402464   AI402489   AI402765   AI402767   AI402941   AI403762   AI403820   AI404225   AI404451   AI404479   AI404614   AI405278   AI405796   AI455949   AI456455   AI456543   AI512081   AI512766   AI513494   AI516909   AI517445   AI517454   AI517474   AI519864   AI531575   AI532673   AI532877   AI543835   AI944753   AI946232   AX201692   AY118449 AAM48478   AY431209   BE662073   BE976425   BE976807   BE977236   BE979018   BF486259   BF487092   BF487580   BF489311   BF491402   BF491415   BF498034   BF499155   BF499507   BF500091   BF503674   BF504482   BF506048   BF506133   BG635809   BG637320   BG638888   BG640787   BG641348   BH759283   BI163202   BI164486   BI164546   BI165267   BI165273   BI166105   BI167055   BI167435   BI167469   BI168136   BI172201   BI172245   BI173269   BI173782   BI213037   BI214657   BI215333   BI216494   BI216819   BI229832   BI230773   BI230809   BI230990   BI232013   BI234978   BI235903   BI236129   BI237663   BI238537   BI238734   BI238840   BI242942   BI243324   BI243433   BI243440   BI351957   BI353291   BI353327   BI353455   BI353948   BI355973   BI361849   BI361988   BI362046   BI363485   BI364265   BI365849   BI367416   BI367929   BI368045   BI371296   BI483181   BI483383   BI484183   BI485965   BI486018   BI486264   BI563776   BI565064   BI565178   BI565713   BI570250   BI570465   BI574839   BI577771   BI578152   BI580688   BI589333   BI589959   BI605128   BI606195   BI608734   BI610298   BI611571   BI611626   BI615705   BI619385   BI624206   BI624794   BI628159   BI630964   BI632559   BI632714   BI633298   BI635349   BI635560   BI635833   BI636055   BI636630   BI637546   BI637580   BI639479   BI639883   BI640480   BI640730   BQ102762   BQ103032   BQ103316   BQ103609   BT014924   BT023114   BT058002   BT072929   BX007835   BX013967   BX018948   BX020873   BX026179   BX026463   BX027683   BX028564   BX031580   BX036808   BX036937   BX041556   BX042900   BX044062   BX051880   BX054124   BX065472   BX070348   CK131701   CK132393   CK604707   CK604708   CK657502   CK659074   CK659836   CK660430   CK660481   CK660926   CK661197   CK661937   CL632133   CO154408   CO154815   CO156446   CO156769   CO271311   CO274423   CO280177   CO280970   CO296493   CO301153   CO302991   CO303342   CO305478   CO306003   CO310769   CO310926   CO330342   CO336696   CZ475931   CZ476946   EC061649   EC065970   EC085954   EC087707   EC088558   EC198964   EC199305   EC201727   EC223175   EC232597   EC236644   EC239403   EC261020   EC262180   EC262819   EC263287   EC265800   EC267246   EL871350   EL871351   EL872528   EL878501   EL883682   EV576023   EV577316   EV578218   EV578265   EV578321   EV578364   EV578873   EV578880   EV579113   EV580711   EV581979   EV583810   EV583993   EV584245   EV585480   EV585913   EV586809   EV587099   EV587950   EV589171   EV589665   EV590852   EV591204   EV592960   EV592972   EV595449   EV596466   EV596501   EV597102   EV597400   EV599930   EV599994   EV600055   GH942096   GH947121   GH948310   GH968071   GH970627   GH973289   GH974984   GH979528   GH980933   GH982399   L80125   X17034 CAA34895
UniProtKB/Swiss-Prot	P15007
UniProtKB/TrEMBL	E1JHR5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference third instar larval stage   wing disc   (Santaren et al., 1993) mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Dorus et al., 2006, Wasbrough et al., 2010) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1929.275 Larval Midgut    1266.1 Larval Hindgut    1904.3 Larval Malpighian Tubules    1616 Larval Fat Body    1834.3 Larval Salivary Gland    2022.3 Larval Trachea    1752.525 Larval Carcass    4135.075 Adult Head    2501.2 Adult Eye    2842.875 Adult Brain    2054.7 Adult Thoracic-Abdominal Ganglion    2565.2 Adult Crop    2729.6 Adult Midgut    1646.6 Adult Hindgut    3133 Adult Malpighian Tubules    2158.2 Adult Fat Body    3663.1 Adult Salivary Gland    4581.4 Adult Heart    3610.45 Adult VirginFemale Spermatheca    3402.9 Adult InseminatedFemale Spermatheca    3312.2 Adult Ovary    1802.7 Adult Testis    959.5 Adult Male Accessory Gland    1645.1 Adult Carcass    4287.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1929.275) Larval Midgut  (1266.1) Larval Hindgut  (1904.3) Larval Malpighian Tubules  (1616) Larval Fat Body  (1834.3) Larval Salivary Gland  (2022.3) Larval Trachea  (1752.525) Larval Carcass  (4135.075) Adult Head  (2501.2) Adult Eye  (2842.875) Adult Brain  (2054.7) Adult Thoracic-Abdominal Ganglion  (2565.2) Adult Crop  (2729.6) Adult Midgut  (1646.6) Adult Hindgut  (3133) Adult Malpighian Tubules  (2158.2) Adult Fat Body  (3663.1) Adult Salivary Gland  (4581.4) Adult Heart  (3610.45) Adult VirginFemale Spermatheca  (3402.9) Adult InseminatedFemale Spermatheca  (3312.2) Adult Ovary  (1802.7) Adult Testis  (959.5) Adult Male Accessory Gland  (1645.1) Adult Carcass  (4287.2) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1929.275) Larval Midgut  (1266.1) Larval Hindgut  (1904.3) Larval Malpighian Tubules  (1616) Larval Fat Body  (1834.3) Larval Salivary Gland  (2022.3) Larval Trachea  (1752.525) Larval Carcass  (4135.075) Adult Head  (2501.2) Adult Eye  (2842.875) Adult Brain  (2054.7) Adult Thoracic-Abdominal Ganglion  (2565.2) Adult Crop  (2729.6) Adult Midgut  (1646.6) Adult Hindgut  (3133) Adult Malpighian Tubules  (2158.2) Adult Fat Body  (3663.1) Adult Salivary Gland  (4581.4) Adult Heart  (3610.45) Adult VirginFemale Spermatheca  (3402.9) Adult InseminatedFemale Spermatheca  (3312.2) Adult Ovary  (1802.7) Adult Testis    959.5 Adult Male Accessory Gland  (1645.1) Adult Carcass  (4287.2) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1929.275 Larval Midgut    1266.1 Larval Hindgut    1904.3 Larval Malpighian Tubules    1616 Larval Fat Body    1834.3 Larval Salivary Gland    2022.3 Larval Trachea    1752.525 Larval Carcass    4135.075 Adult Head    2501.2 Adult Eye    2842.875 Adult Brain    2054.7 Adult Thoracic-Abdominal Ganglion    2565.2 Adult Crop    2729.6 Adult Midgut    1646.6 Adult Hindgut    3133 Adult Malpighian Tubules    2158.2 Adult Fat Body    3663.1 Adult Salivary Gland    4581.4 Adult Heart    3610.45 Adult VirginFemale Spermatheca    3402.9 Adult InseminatedFemale Spermatheca    3312.2 Adult Ovary    1802.7 Adult Testis    959.5 Adult Male Accessory Gland    1645.1 Adult Carcass    4287.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1929.275 Larval Midgut    1266.1 Larval Hindgut    1904.3 Larval Malpighian Tubules    1616 Larval Fat Body    1834.3 Larval Salivary Gland    2022.3 Larval Trachea    1752.525 Larval Carcass    4135.075 Adult Head    2501.2 Adult Eye    2842.875 Adult Brain    2054.7 Adult Thoracic-Abdominal Ganglion    2565.2 Adult Crop    2729.6 Adult Midgut    1646.6 Adult Hindgut    3133 Adult Malpighian Tubules    2158.2 Adult Fat Body    3663.1 Adult Salivary Gland    4581.4 Adult Heart    3610.45 Adult VirginFemale Spermatheca    3402.9 Adult InseminatedFemale Spermatheca    3312.2 Adult Ovary    1802.7 Adult Testis    959.5 Adult Male Accessory Gland    1645.1 Adult Carcass    4287.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1929.275) Larval Midgut  (1266.1) Larval Hindgut  (1904.3) Larval Malpighian Tubules  (1616) Larval Fat Body  (1834.3) Larval Salivary Gland  (2022.3) Larval Trachea  (1752.525) Larval Carcass  (4135.075) Adult Head  (2501.2) Adult Eye  (2842.875) Adult Brain  (2054.7) Adult Thoracic-Abdominal Ganglion  (2565.2) Adult Crop  (2729.6) Adult Midgut  (1646.6) Adult Hindgut  (3133) Adult Malpighian Tubules  (2158.2) Adult Fat Body  (3663.1) Adult Salivary Gland  (4581.4) Adult Heart  (3610.45) Adult VirginFemale Spermatheca  (3402.9) Adult InseminatedFemale Spermatheca  (3312.2) Adult Ovary  (1802.7) Adult Testis  (959.5) Adult Male Accessory Gland  (1645.1) Adult Carcass  (4287.2) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1929.275) Larval Midgut  1266.1 Larval Hindgut  (1904.3) Larval Malpighian Tubules  1616 Larval Fat Body  (1834.3) Larval Salivary Gland  (2022.3) Larval Trachea  (1752.525) Larval Carcass  (4135.075) Adult Head  (2501.2) Adult Eye  (2842.875) Adult Brain  (2054.7) Adult Thoracic-Abdominal Ganglion  (2565.2) Adult Crop  (2729.6) Adult Midgut  1646.6 Adult Hindgut  (3133) Adult Malpighian Tubules  (2158.2) Adult Fat Body  (3663.1) Adult Salivary Gland  (4581.4) Adult Heart  (3610.45) Adult VirginFemale Spermatheca  (3402.9) Adult InseminatedFemale Spermatheca  (3312.2) Adult Ovary  (1802.7) Adult Testis    959.5 Adult Male Accessory Gland  1645.1 Adult Carcass  (4287.2) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1929.275 Larval Midgut    1266.1 Larval Hindgut    1904.3 Larval Malpighian Tubules    1616 Larval Fat Body    1834.3 Larval Salivary Gland    2022.3 Larval Trachea    1752.525 Larval Carcass    4135.075 Adult Head    2501.2 Adult Eye    2842.875 Adult Brain    2054.7 Adult Thoracic-Abdominal Ganglion    2565.2 Adult Crop    2729.6 Adult Midgut    1646.6 Adult Hindgut    3133 Adult Malpighian Tubules    2158.2 Adult Fat Body    3663.1 Adult Salivary Gland    4581.4 Adult Heart    3610.45 Adult VirginFemale Spermatheca    3402.9 Adult InseminatedFemale Spermatheca    3312.2 Adult Ovary    1802.7 Adult Testis    959.5 Adult Male Accessory Gland    1645.1 Adult Carcass    4287.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2501.2   NA  Eye    2842.875   NA  Brain    2054.7   1929.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2565.2   NA  Crop    2729.6   1266.1  Midgut    1646.6   1904.3  Hindgut    3133   1616  Malpighian Tubules    2158.2   1834.3  Fat Body    3663.1   2022.3  Salivary Gland    4581.4   NA  Heart    3610.45   1752.525  Trachea    NA   NA  VirginFemale Spermatheca    3402.9   NA  InseminatedFemale Spermatheca    3312.2   NA  Ovary    1802.7   NA  Testis    959.5   NA  Male Accessory Gland    1645.1   4135.075  Carcass    4287.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    101 central nervous system, pupae P8    55 head, virgin 1-day female    293 head, virgin 4-day female    185 head, virgin 20-day female    281 head, mated 1-day female    196 head, mated 4-day female    141 head, mated 20-day female    210 head, mated 1-day male    331 head, mated 4-day male    237 head, mated 20-day male    294 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult    182 digestive system, 4-day adult    111 digestive system, 20-day adult    143 fat body, larvae L3 wandering    95 fat body, white prepupae    105 fat body, pupae P8    82 carcass, larvae L3 wandering    115 carcass, 1-day adult    643 carcass, 4-day adult    272 carcass, 20-day adult    246 ovary, virgin 4-day female    326 ovary, mated 4-day female    195 testis, mated 4-day male    155 accessory gland, mated 4-day male    125 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (101) central nervous system, pupae P8  (55) head, virgin 1-day female  (293) head, virgin 4-day female  (185) head, virgin 20-day female  (281) head, mated 1-day female  (196) head, mated 4-day female  (141) head, mated 20-day female  (210) head, mated 1-day male  (331) head, mated 4-day male  (237) head, mated 20-day male  (294) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (35) digestive system, larvae L3 wandering  (47) digestive system, 1-day adult  (182) digestive system, 4-day adult  (111) digestive system, 20-day adult  (143) fat body, larvae L3 wandering  (95) fat body, white prepupae  (105) fat body, pupae P8  (82) carcass, larvae L3 wandering  (115) carcass, 1-day adult  (643) carcass, 4-day adult  (272) carcass, 20-day adult  (246) ovary, virgin 4-day female  (326) ovary, mated 4-day female  (195) testis, mated 4-day male  (155) accessory gland, mated 4-day male  (125) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  101 central nervous system, pupae P8    55 head, virgin 1-day female  (293) head, virgin 4-day female  (185) head, virgin 20-day female  (281) head, mated 1-day female  (196) head, mated 4-day female  (141) head, mated 20-day female  (210) head, mated 1-day male  (331) head, mated 4-day male  (237) head, mated 20-day male  (294) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult  (182) digestive system, 4-day adult  (111) digestive system, 20-day adult  (143) fat body, larvae L3 wandering    95 fat body, white prepupae  105 fat body, pupae P8    82 carcass, larvae L3 wandering  (115) carcass, 1-day adult  (643) carcass, 4-day adult  (272) carcass, 20-day adult  (246) ovary, virgin 4-day female  (326) ovary, mated 4-day female  (195) testis, mated 4-day male  (155) accessory gland, mated 4-day male  (125) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    101 central nervous system, pupae P8    55 head, virgin 1-day female    293 head, virgin 4-day female    185 head, virgin 20-day female    281 head, mated 1-day female    196 head, mated 4-day female    141 head, mated 20-day female    210 head, mated 1-day male    331 head, mated 4-day male    237 head, mated 20-day male    294 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult    182 digestive system, 4-day adult    111 digestive system, 20-day adult    143 fat body, larvae L3 wandering    95 fat body, white prepupae    105 fat body, pupae P8    82 carcass, larvae L3 wandering    115 carcass, 1-day adult    643 carcass, 4-day adult    272 carcass, 20-day adult    246 ovary, virgin 4-day female    326 ovary, mated 4-day female    195 testis, mated 4-day male    155 accessory gland, mated 4-day male    125 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    101 central nervous system, pupae P8    55 head, virgin 1-day female    293 head, virgin 4-day female    185 head, virgin 20-day female    281 head, mated 1-day female    196 head, mated 4-day female    141 head, mated 20-day female    210 head, mated 1-day male    331 head, mated 4-day male    237 head, mated 20-day male    294 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult    182 digestive system, 4-day adult    111 digestive system, 20-day adult    143 fat body, larvae L3 wandering    95 fat body, white prepupae    105 fat body, pupae P8    82 carcass, larvae L3 wandering    115 carcass, 1-day adult    643 carcass, 4-day adult    272 carcass, 20-day adult    246 ovary, virgin 4-day female    326 ovary, mated 4-day female    195 testis, mated 4-day male    155 accessory gland, mated 4-day male    125 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (101) central nervous system, pupae P8  (55) head, virgin 1-day female  (293) head, virgin 4-day female  (185) head, virgin 20-day female  (281) head, mated 1-day female  (196) head, mated 4-day female  (141) head, mated 20-day female  (210) head, mated 1-day male  (331) head, mated 4-day male  (237) head, mated 20-day male  (294) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (35) digestive system, larvae L3 wandering  (47) digestive system, 1-day adult  (182) digestive system, 4-day adult  (111) digestive system, 20-day adult  (143) fat body, larvae L3 wandering  (95) fat body, white prepupae  (105) fat body, pupae P8  (82) carcass, larvae L3 wandering  (115) carcass, 1-day adult  (643) carcass, 4-day adult  (272) carcass, 20-day adult  (246) ovary, virgin 4-day female  (326) ovary, mated 4-day female  (195) testis, mated 4-day male  (155) accessory gland, mated 4-day male  (125) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  101 central nervous system, pupae P8    55 head, virgin 1-day female  (293) head, virgin 4-day female  (185) head, virgin 20-day female  (281) head, mated 1-day female  (196) head, mated 4-day female  141 head, mated 20-day female  (210) head, mated 1-day male  (331) head, mated 4-day male  (237) head, mated 20-day male  (294) salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult  (182) digestive system, 4-day adult  111 digestive system, 20-day adult  143 fat body, larvae L3 wandering    95 fat body, white prepupae  105 fat body, pupae P8    82 carcass, larvae L3 wandering  115 carcass, 1-day adult  (643) carcass, 4-day adult  (272) carcass, 20-day adult  (246) ovary, virgin 4-day female  (326) ovary, mated 4-day female  (195) testis, mated 4-day male  (155) accessory gland, mated 4-day male  125 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    101 central nervous system, pupae P8    55 head, virgin 1-day female    293 head, virgin 4-day female    185 head, virgin 20-day female    281 head, mated 1-day female    196 head, mated 4-day female    141 head, mated 20-day female    210 head, mated 1-day male    331 head, mated 4-day male    237 head, mated 20-day male    294 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    47 digestive system, 1-day adult    182 digestive system, 4-day adult    111 digestive system, 20-day adult    143 fat body, larvae L3 wandering    95 fat body, white prepupae    105 fat body, pupae P8    82 carcass, larvae L3 wandering    115 carcass, 1-day adult    643 carcass, 4-day adult    272 carcass, 20-day adult    246 ovary, virgin 4-day female    326 ovary, mated 4-day female    195 testis, mated 4-day male    155 accessory gland, mated 4-day male    125 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    409 embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr    107 embryo 12-14hr    84 embryo 14-16hr    130 embryo 16-18hr    104 embryo 18-20hr    175 embryo 20-22hr    294 embryo 22-24hr    281 larva L1    555 larva L2    651 larva L3 12hr old    725 larva L3 puffstage 1-2    490 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    114 white prepupae new    106 white prepupae 12hr    71 white prepupae 24hr    106 pupae 2d postWPP    137 pupae 3d postWPP    312 pupae 4d postWPP    605 adult male 01day    720 adult male 05day    597 adult male 30day    250 adult female 01day    621 adult female 05day    333 adult female 30day    294 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (409) embryo 02-04hr  (89) embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr  (107) embryo 12-14hr  (84) embryo 14-16hr  (130) embryo 16-18hr  (104) embryo 18-20hr  (175) embryo 20-22hr  (294) embryo 22-24hr  (281) larva L1  (555) larva L2  (651) larva L3 12hr old  (725) larva L3 puffstage 1-2  (490) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  (114) white prepupae new  (106) white prepupae 12hr  (71) white prepupae 24hr  (106) pupae 2d postWPP  (137) pupae 3d postWPP  (312) pupae 4d postWPP  (605) adult male 01day  (720) adult male 05day  (597) adult male 30day  (250) adult female 01day  (621) adult female 05day  (333) adult female 30day  (294) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (409) embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr  107 embryo 12-14hr    84 embryo 14-16hr  (130) embryo 16-18hr  104 embryo 18-20hr  (175) embryo 20-22hr  (294) embryo 22-24hr  (281) larva L1  (555) larva L2  (651) larva L3 12hr old  (725) larva L3 puffstage 1-2  (490) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  (114) white prepupae new  106 white prepupae 12hr    71 white prepupae 24hr  106 pupae 2d postWPP  (137) pupae 3d postWPP  (312) pupae 4d postWPP  (605) adult male 01day  (720) adult male 05day  (597) adult male 30day  (250) adult female 01day  (621) adult female 05day  (333) adult female 30day  (294) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    409 embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr    107 embryo 12-14hr    84 embryo 14-16hr    130 embryo 16-18hr    104 embryo 18-20hr    175 embryo 20-22hr    294 embryo 22-24hr    281 larva L1    555 larva L2    651 larva L3 12hr old    725 larva L3 puffstage 1-2    490 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    114 white prepupae new    106 white prepupae 12hr    71 white prepupae 24hr    106 pupae 2d postWPP    137 pupae 3d postWPP    312 pupae 4d postWPP    605 adult male 01day    720 adult male 05day    597 adult male 30day    250 adult female 01day    621 adult female 05day    333 adult female 30day    294 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    409 embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr    107 embryo 12-14hr    84 embryo 14-16hr    130 embryo 16-18hr    104 embryo 18-20hr    175 embryo 20-22hr    294 embryo 22-24hr    281 larva L1    555 larva L2    651 larva L3 12hr old    725 larva L3 puffstage 1-2    490 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    114 white prepupae new    106 white prepupae 12hr    71 white prepupae 24hr    106 pupae 2d postWPP    137 pupae 3d postWPP    312 pupae 4d postWPP    605 adult male 01day    720 adult male 05day    597 adult male 30day    250 adult female 01day    621 adult female 05day    333 adult female 30day    294 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (409) embryo 02-04hr  (89) embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr  (107) embryo 12-14hr  (84) embryo 14-16hr  (130) embryo 16-18hr  (104) embryo 18-20hr  (175) embryo 20-22hr  (294) embryo 22-24hr  (281) larva L1  (555) larva L2  (651) larva L3 12hr old  (725) larva L3 puffstage 1-2  (490) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  (114) white prepupae new  (106) white prepupae 12hr  (71) white prepupae 24hr  (106) pupae 2d postWPP  (137) pupae 3d postWPP  (312) pupae 4d postWPP  (605) adult male 01day  (720) adult male 05day  (597) adult male 30day  (250) adult female 01day  (621) adult female 05day  (333) adult female 30day  (294) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (409) embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr  107 embryo 12-14hr    84 embryo 14-16hr  130 embryo 16-18hr  104 embryo 18-20hr  (175) embryo 20-22hr  (294) embryo 22-24hr  (281) larva L1  (555) larva L2  (651) larva L3 12hr old  (725) larva L3 puffstage 1-2  (490) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  114 white prepupae new  106 white prepupae 12hr    71 white prepupae 24hr  106 pupae 2d postWPP  137 pupae 3d postWPP  (312) pupae 4d postWPP  (605) adult male 01day  (720) adult male 05day  (597) adult male 30day  (250) adult female 01day  (621) adult female 05day  (333) adult female 30day  (294) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    409 embryo 02-04hr    89 embryo 04-06hr    14 embryo 06-08hr    12 embryo 08-10hr    21 embryo 10-12hr    107 embryo 12-14hr    84 embryo 14-16hr    130 embryo 16-18hr    104 embryo 18-20hr    175 embryo 20-22hr    294 embryo 22-24hr    281 larva L1    555 larva L2    651 larva L3 12hr old    725 larva L3 puffstage 1-2    490 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    114 white prepupae new    106 white prepupae 12hr    71 white prepupae 24hr    106 pupae 2d postWPP    137 pupae 3d postWPP    312 pupae 4d postWPP    605 adult male 01day    720 adult male 05day    597 adult male 30day    250 adult female 01day    621 adult female 05day    333 adult female 30day    294 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    149 Schneider line 2 Sg4    197 embryonic 1182-4H    142 embryonic GM2    168 embryonic Kc167    225 embryonic S1    127 embryonic S3    121 leg disc CME L1    170 wing disc CME-W2    251 wing disc ML-DmD8    310 wing disc ML-DmD9    251 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    172 wing disc ML-DmD32    145 haltere disc ML-DmD17-c3    139 eye-antennal disc ML-DmD11    227 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    243 CNS ML-DmBG1-c1    232 CNS ML-DmBG2-c2    243 tumorous blood cells mbn2    182 ovary fGS/OSS    155 ovary OSC    91 ovary OSS    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (149) Schneider line 2 Sg4  (197) embryonic 1182-4H  (142) embryonic GM2  (168) embryonic Kc167  (225) embryonic S1  (127) embryonic S3  (121) leg disc CME L1  (170) wing disc CME-W2  (251) wing disc ML-DmD8  (310) wing disc ML-DmD9  (251) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (172) wing disc ML-DmD32  (145) haltere disc ML-DmD17-c3  (139) eye-antennal disc ML-DmD11  (227) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (243) CNS ML-DmBG1-c1  (232) CNS ML-DmBG2-c2  (243) tumorous blood cells mbn2  (182) ovary fGS/OSS  (155) ovary OSC  (91) ovary OSS  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (149) Schneider line 2 Sg4  (197) embryonic 1182-4H  (142) embryonic GM2  (168) embryonic Kc167  (225) embryonic S1  (127) embryonic S3  (121) leg disc CME L1  (170) wing disc CME-W2  (251) wing disc ML-DmD8  (310) wing disc ML-DmD9  (251) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (172) wing disc ML-DmD32  (145) haltere disc ML-DmD17-c3  (139) eye-antennal disc ML-DmD11  (227) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (243) CNS ML-DmBG1-c1  (232) CNS ML-DmBG2-c2  (243) tumorous blood cells mbn2  (182) ovary fGS/OSS  (155) ovary OSC    91 ovary OSS    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    149 Schneider line 2 Sg4    197 embryonic 1182-4H    142 embryonic GM2    168 embryonic Kc167    225 embryonic S1    127 embryonic S3    121 leg disc CME L1    170 wing disc CME-W2    251 wing disc ML-DmD8    310 wing disc ML-DmD9    251 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    172 wing disc ML-DmD32    145 haltere disc ML-DmD17-c3    139 eye-antennal disc ML-DmD11    227 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    243 CNS ML-DmBG1-c1    232 CNS ML-DmBG2-c2    243 tumorous blood cells mbn2    182 ovary fGS/OSS    155 ovary OSC    91 ovary OSS    43 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    149 Schneider line 2 Sg4    197 embryonic 1182-4H    142 embryonic GM2    168 embryonic Kc167    225 embryonic S1    127 embryonic S3    121 leg disc CME L1    170 wing disc CME-W2    251 wing disc ML-DmD8    310 wing disc ML-DmD9    251 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    172 wing disc ML-DmD32    145 haltere disc ML-DmD17-c3    139 eye-antennal disc ML-DmD11    227 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    243 CNS ML-DmBG1-c1    232 CNS ML-DmBG2-c2    243 tumorous blood cells mbn2    182 ovary fGS/OSS    155 ovary OSC    91 ovary OSS    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (149) Schneider line 2 Sg4  (197) embryonic 1182-4H  (142) embryonic GM2  (168) embryonic Kc167  (225) embryonic S1  (127) embryonic S3  (121) leg disc CME L1  (170) wing disc CME-W2  (251) wing disc ML-DmD8  (310) wing disc ML-DmD9  (251) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (172) wing disc ML-DmD32  (145) haltere disc ML-DmD17-c3  (139) eye-antennal disc ML-DmD11  (227) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (243) CNS ML-DmBG1-c1  (232) CNS ML-DmBG2-c2  (243) tumorous blood cells mbn2  (182) ovary fGS/OSS  (155) ovary OSC  (91) ovary OSS  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (149) Schneider line 2 Sg4  (197) embryonic 1182-4H  142 embryonic GM2  (168) embryonic Kc167  (225) embryonic S1  127 embryonic S3  121 leg disc CME L1  (170) wing disc CME-W2  (251) wing disc ML-DmD8  (310) wing disc ML-DmD9  (251) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (172) wing disc ML-DmD32  (145) haltere disc ML-DmD17-c3  139 eye-antennal disc ML-DmD11  (227) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (243) CNS ML-DmBG1-c1  (232) CNS ML-DmBG2-c2  (243) tumorous blood cells mbn2  (182) ovary fGS/OSS  (155) ovary OSC    91 ovary OSS    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    149 Schneider line 2 Sg4    197 embryonic 1182-4H    142 embryonic GM2    168 embryonic Kc167    225 embryonic S1    127 embryonic S3    121 leg disc CME L1    170 wing disc CME-W2    251 wing disc ML-DmD8    310 wing disc ML-DmD9    251 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    172 wing disc ML-DmD32    145 haltere disc ML-DmD17-c3    139 eye-antennal disc ML-DmD11    227 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    243 CNS ML-DmBG1-c1    232 CNS ML-DmBG2-c2    243 tumorous blood cells mbn2    182 ovary fGS/OSS    155 ovary OSC    91 ovary OSS    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    75 heat shock, 4-day adult    424 Cadmium 50 mM 6 hrs, larvae L3    594 Cadmium 50 mM 12 hrs, larvae L3    380 Cadmium 50 mM 48 hrs, 4-day adult    384 Cadmium 100 mM 48 hrs, 4-day adult    216 Copper 0.5 mM 12 hrs, larvae L3    383 Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3    231 Zinc 4.5 mM 48 hrs, 4-day adult    127 Ethanol 2.5% 3 hrs, larvae L3    373 Ethanol 5% 3 hrs, larvae L3    493 Ethanol 10% 3 hrs, larvae L3    590 Caffeine 1.5 mg/ml 4 hrs, larvae L3    478 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    219 Caffeine 25 mg/ml 48 hrs, 4-day adult    104 Paraquat 5 mM 48 hrs, 4-day adult    308 Paraquat 10 mM 48 hrs, 4-day adult    380 Rotenone 2 μg 12 hrs, larvae L3    506 Rotenone 8 μg 12 hrs, larvae L3    720 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult  (75) heat shock, 4-day adult  (424) Cadmium 50 mM 6 hrs, larvae L3  (594) Cadmium 50 mM 12 hrs, larvae L3  (380) Cadmium 50 mM 48 hrs, 4-day adult  (384) Cadmium 100 mM 48 hrs, 4-day adult  (216) Copper 0.5 mM 12 hrs, larvae L3  (383) Copper 15 mM 48 hrs, 4-day adult  (99) Zinc 5 mM 12 hrs, larvae L3  (231) Zinc 4.5 mM 48 hrs, 4-day adult  (127) Ethanol 2.5% 3 hrs, larvae L3  (373) Ethanol 5% 3 hrs, larvae L3  (493) Ethanol 10% 3 hrs, larvae L3  (590) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (478) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (219) Caffeine 25 mg/ml 48 hrs, 4-day adult  (104) Paraquat 5 mM 48 hrs, 4-day adult  (308) Paraquat 10 mM 48 hrs, 4-day adult  (380) Rotenone 2 μg 12 hrs, larvae L3  (506) Rotenone 8 μg 12 hrs, larvae L3  (720) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult    75 heat shock, 4-day adult  (424) Cadmium 50 mM 6 hrs, larvae L3  (594) Cadmium 50 mM 12 hrs, larvae L3  (380) Cadmium 50 mM 48 hrs, 4-day adult  (384) Cadmium 100 mM 48 hrs, 4-day adult  (216) Copper 0.5 mM 12 hrs, larvae L3  (383) Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3  (231) Zinc 4.5 mM 48 hrs, 4-day adult  (127) Ethanol 2.5% 3 hrs, larvae L3  (373) Ethanol 5% 3 hrs, larvae L3  (493) Ethanol 10% 3 hrs, larvae L3  (590) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (478) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (219) Caffeine 25 mg/ml 48 hrs, 4-day adult  104 Paraquat 5 mM 48 hrs, 4-day adult  (308) Paraquat 10 mM 48 hrs, 4-day adult  (380) Rotenone 2 μg 12 hrs, larvae L3  (506) Rotenone 8 μg 12 hrs, larvae L3  (720) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    75 heat shock, 4-day adult    424 Cadmium 50 mM 6 hrs, larvae L3    594 Cadmium 50 mM 12 hrs, larvae L3    380 Cadmium 50 mM 48 hrs, 4-day adult    384 Cadmium 100 mM 48 hrs, 4-day adult    216 Copper 0.5 mM 12 hrs, larvae L3    383 Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3    231 Zinc 4.5 mM 48 hrs, 4-day adult    127 Ethanol 2.5% 3 hrs, larvae L3    373 Ethanol 5% 3 hrs, larvae L3    493 Ethanol 10% 3 hrs, larvae L3    590 Caffeine 1.5 mg/ml 4 hrs, larvae L3    478 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    219 Caffeine 25 mg/ml 48 hrs, 4-day adult    104 Paraquat 5 mM 48 hrs, 4-day adult    308 Paraquat 10 mM 48 hrs, 4-day adult    380 Rotenone 2 μg 12 hrs, larvae L3    506 Rotenone 8 μg 12 hrs, larvae L3    720 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    75 heat shock, 4-day adult    424 Cadmium 50 mM 6 hrs, larvae L3    594 Cadmium 50 mM 12 hrs, larvae L3    380 Cadmium 50 mM 48 hrs, 4-day adult    384 Cadmium 100 mM 48 hrs, 4-day adult    216 Copper 0.5 mM 12 hrs, larvae L3    383 Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3    231 Zinc 4.5 mM 48 hrs, 4-day adult    127 Ethanol 2.5% 3 hrs, larvae L3    373 Ethanol 5% 3 hrs, larvae L3    493 Ethanol 10% 3 hrs, larvae L3    590 Caffeine 1.5 mg/ml 4 hrs, larvae L3    478 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    219 Caffeine 25 mg/ml 48 hrs, 4-day adult    104 Paraquat 5 mM 48 hrs, 4-day adult    308 Paraquat 10 mM 48 hrs, 4-day adult    380 Rotenone 2 μg 12 hrs, larvae L3    506 Rotenone 8 μg 12 hrs, larvae L3    720 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult  (75) heat shock, 4-day adult  (424) Cadmium 50 mM 6 hrs, larvae L3  (594) Cadmium 50 mM 12 hrs, larvae L3  (380) Cadmium 50 mM 48 hrs, 4-day adult  (384) Cadmium 100 mM 48 hrs, 4-day adult  (216) Copper 0.5 mM 12 hrs, larvae L3  (383) Copper 15 mM 48 hrs, 4-day adult  (99) Zinc 5 mM 12 hrs, larvae L3  (231) Zinc 4.5 mM 48 hrs, 4-day adult  (127) Ethanol 2.5% 3 hrs, larvae L3  (373) Ethanol 5% 3 hrs, larvae L3  (493) Ethanol 10% 3 hrs, larvae L3  (590) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (478) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (219) Caffeine 25 mg/ml 48 hrs, 4-day adult  (104) Paraquat 5 mM 48 hrs, 4-day adult  (308) Paraquat 10 mM 48 hrs, 4-day adult  (380) Rotenone 2 μg 12 hrs, larvae L3  (506) Rotenone 8 μg 12 hrs, larvae L3  (720) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  117 cold shock, 4-day adult    75 heat shock, 4-day adult  (424) Cadmium 50 mM 6 hrs, larvae L3  (594) Cadmium 50 mM 12 hrs, larvae L3  (380) Cadmium 50 mM 48 hrs, 4-day adult  (384) Cadmium 100 mM 48 hrs, 4-day adult  (216) Copper 0.5 mM 12 hrs, larvae L3  (383) Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3  (231) Zinc 4.5 mM 48 hrs, 4-day adult  127 Ethanol 2.5% 3 hrs, larvae L3  (373) Ethanol 5% 3 hrs, larvae L3  (493) Ethanol 10% 3 hrs, larvae L3  (590) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (478) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (219) Caffeine 25 mg/ml 48 hrs, 4-day adult  104 Paraquat 5 mM 48 hrs, 4-day adult  (308) Paraquat 10 mM 48 hrs, 4-day adult  (380) Rotenone 2 μg 12 hrs, larvae L3  (506) Rotenone 8 μg 12 hrs, larvae L3  (720) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    75 heat shock, 4-day adult    424 Cadmium 50 mM 6 hrs, larvae L3    594 Cadmium 50 mM 12 hrs, larvae L3    380 Cadmium 50 mM 48 hrs, 4-day adult    384 Cadmium 100 mM 48 hrs, 4-day adult    216 Copper 0.5 mM 12 hrs, larvae L3    383 Copper 15 mM 48 hrs, 4-day adult    99 Zinc 5 mM 12 hrs, larvae L3    231 Zinc 4.5 mM 48 hrs, 4-day adult    127 Ethanol 2.5% 3 hrs, larvae L3    373 Ethanol 5% 3 hrs, larvae L3    493 Ethanol 10% 3 hrs, larvae L3    590 Caffeine 1.5 mg/ml 4 hrs, larvae L3    478 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    219 Caffeine 25 mg/ml 48 hrs, 4-day adult    104 Paraquat 5 mM 48 hrs, 4-day adult    308 Paraquat 10 mM 48 hrs, 4-day adult    380 Rotenone 2 μg 12 hrs, larvae L3    506 Rotenone 8 μg 12 hrs, larvae L3    720 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_10 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0000579 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17654-RB;CG31287-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal EnoCB02039 viable EnoEY02251 Sterility Allele fertile EnoEY02251 Phenotype manifest in Allele
Classical Alleles ( 14 )
For All Classical Alleles Show
Allele of Eno Class Mutagen Stocks Known lesion Enoe01615 piggyBac transposase 3 -- Enof07543 piggyBac transposase 3 -- Eno5-SZ-4004 1 -- Enod07810 P-element activity 1 -- EnoEY02251 P-element activity 1 -- EnoEY23161 P-element activity 1 -- EnoG5958 P-element activity 1 -- EnoKG01162 P-element activity 1 -- EnoNP2353 1 -- EnoUM-8172-3 1 -- Eno222A natural population 0 -- Eno30A natural population 0 -- EnoCB02039 P-element activity 0 Yes Enod09795 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Eno Class Mutagen Stocks Known lesion EnoGL01229 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes EnoJF02070 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes EnoGD9436 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes EnoKK100571 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes EnoNIG.17654R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6005 (Ryder, 2004.4.26) Df(2L)Exel7007 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9436} NA P{KK100571} NA P{NIG.17654R} NA P{TRiP.GL01229} NA P{TRiP.JF02070} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}EnoG5958 NA P{EPgy2}EnoEY02251 NA P{EPgy2}EnoEY23161 NA P{XP}Enod07810 NA P{XP}Enod09795 NA miscellaneous insertions P{PTT-GB}EnoCB02039 NA P{RS3}EnoUM-8172-3 NA P{RS5}Eno5-SZ-4004 NA P{SUPor-P}EnoKG01162 NA PBac{RB}Enoe01615 NA PBac{WH}Enof07543 NA insertion of enhancer trap binary system P{GawB}EnoNP2353 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
magnesium ion binding inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 (FlyBase Curators et al., 2004-) phosphopyruvate hydratase activity inferred from sequence or structural similarity with UniProtKB:O96656 AND inferred from sequence or structural similarity with UniProt:P08734 (FlyBase, 1992-)
Biological Process
CV term Evidence References
glycolysis inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 (FlyBase Curators et al., 2004-) non-traceable author statement (Swiss-Prot Project Members, 1990.4.1)
Cellular Component
CV term Evidence References
phosphopyruvate hydratase complex inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Eno - 14-3-3ε experimental knowledge based (Guruharsha et al., 2011) Eno - 5-HT7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - ATPsyn-Cf6 experimental knowledge based (Guruharsha et al., 2011) Eno - ATPsyn-β experimental knowledge based (Guruharsha et al., 2011) Eno - Aats-his anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Acon experimental knowledge based (Guruharsha et al., 2011) Eno - Adh experimental knowledge based (Guruharsha et al., 2011) Eno - Akap200 experimental knowledge based (Guruharsha et al., 2011) Eno - Ald experimental knowledge based (Guruharsha et al., 2011) Eno - AnxB10 experimental knowledge based (Guruharsha et al., 2011) Eno - Argk experimental knowledge based (Guruharsha et al., 2011) Eno - Bacc experimental knowledge based (Guruharsha et al., 2011) Eno - CG10581 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG10638 experimental knowledge based (Guruharsha et al., 2011) Eno - CG10694 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG11267 experimental knowledge based (Guruharsha et al., 2011) Eno - CG11796 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG13539 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG13618 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG13698 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG14262 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG14715 experimental knowledge based (Guruharsha et al., 2011) Eno - CG14762 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG14968 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG18335 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG18347 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG2852 experimental knowledge based (Guruharsha et al., 2011) Eno - CG2862 experimental knowledge based (Guruharsha et al., 2011) Eno - CG2931 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG30339 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3038 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3088 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3226 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3303 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG34133 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3819 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG3919 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG40160 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG42319 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG4278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG4302 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG4415 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG4598 experimental knowledge based (Guruharsha et al., 2011) Eno - CG5380 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG5382 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG5500 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG5577 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG5646 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG5986 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG6084 experimental knowledge based (Guruharsha et al., 2011) Eno - CG6321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG6330 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG7091 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG7288 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG7911 experimental knowledge based (Guruharsha et al., 2011) Eno - CG8005 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG8036 experimental knowledge based (Guruharsha et al., 2011) Eno - CG8117 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG8132 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG8568 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG8680 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - CG8993 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Eno - CG9890 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Ccp84Ac anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Chd64 experimental knowledge based (Guruharsha et al., 2011) Eno - Ciao1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Clp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Cpr11B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Crc experimental knowledge based (Guruharsha et al., 2011) Eno - CrebB anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Cyp1 experimental knowledge based (Guruharsha et al., 2011) Eno - D1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Der-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Df31 experimental knowledge based (Guruharsha et al., 2011) Eno - Drip anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - E(spl)mγ-HLH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Ef2b experimental knowledge based (Guruharsha et al., 2011) Eno - EndoGI experimental knowledge based (Guruharsha et al., 2011) Eno - FK506-bp2 experimental knowledge based (Guruharsha et al., 2011) Eno - Fkbp13 experimental knowledge based (Guruharsha et al., 2011) Eno - Gapdh2 experimental knowledge based (Guruharsha et al., 2011) Eno - Gdi experimental knowledge based (Guruharsha et al., 2011) Eno - Gpdh experimental knowledge based (Guruharsha et al., 2011) Eno - GstE6 experimental knowledge based (Guruharsha et al., 2011) Eno - GstO3 experimental knowledge based (Guruharsha et al., 2011) Eno - GstS1 experimental knowledge based (Guruharsha et al., 2011) Eno - Gαi anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Hop experimental knowledge based (Guruharsha et al., 2011) Eno - Hsc70Cb experimental knowledge based (Guruharsha et al., 2011) Eno - Iap2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Inos experimental knowledge based (Guruharsha et al., 2011) Eno - Kdm4A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Mdh2 experimental knowledge based (Guruharsha et al., 2011) Eno - Mip anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Mlc1 experimental knowledge based (Guruharsha et al., 2011) Eno - Mlc2 experimental knowledge based (Guruharsha et al., 2011) Eno - Moe experimental knowledge based (Guruharsha et al., 2011) Eno - Nacα experimental knowledge based (Guruharsha et al., 2011) Eno - Nlp experimental knowledge based (Guruharsha et al., 2011) Eno - Npc2g anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Ntf-2 experimental knowledge based (Guruharsha et al., 2011) Eno - Obp19c anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - PHGPx experimental knowledge based (Guruharsha et al., 2011) Eno - PI31 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Pdi experimental knowledge based (Guruharsha et al., 2011) Eno - Pex16 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Pgd experimental knowledge based (Guruharsha et al., 2011) Eno - Pgk experimental knowledge based (Guruharsha et al., 2011) Eno - Pglym78 experimental knowledge based (Guruharsha et al., 2011) Eno - Pli anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Proct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Prosα1 experimental knowledge based (Guruharsha et al., 2011) Eno - Prosα2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Prosα5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Prosβ5 experimental knowledge based (Guruharsha et al., 2011) Eno - Prx2540-2 experimental knowledge based (Guruharsha et al., 2011) Eno - Rab18 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Rab7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - RagC-D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - RhoGDI experimental knowledge based (Guruharsha et al., 2011) Eno - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - RpS5a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - SP2637 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Sar1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Scp1 experimental knowledge based (Guruharsha et al., 2011) Eno - Sh3β experimental knowledge based (Guruharsha et al., 2011) Eno - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Snp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Sod experimental knowledge based (Guruharsha et al., 2011) Eno - Sod2 experimental knowledge based (Guruharsha et al., 2011) Eno - Takr86C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - Tctp experimental knowledge based (Guruharsha et al., 2011) Eno - Tm2 experimental knowledge based (Guruharsha et al., 2011) Eno - Trx-2 experimental knowledge based (Guruharsha et al., 2011) Eno - Trxr-1 experimental knowledge based (Guruharsha et al., 2011) Eno - Uch experimental knowledge based (Guruharsha et al., 2011) Eno - Wwox anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - aur anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - ave anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - awd experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Eno - bai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - bys anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - capt experimental knowledge based (Guruharsha et al., 2011) Eno - chic experimental knowledge based (Guruharsha et al., 2011) Eno - cib experimental knowledge based (Guruharsha et al., 2011) Eno - dUTPase experimental knowledge based (Guruharsha et al., 2011) Eno - dlg1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - eEF1δ experimental knowledge based (Guruharsha et al., 2011) Eno - eIF-5A experimental knowledge based (Guruharsha et al., 2011) Eno - fabp experimental knowledge based (Guruharsha et al., 2011) Eno - fbp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - fd59A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - fzr2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - kdn experimental knowledge based (Guruharsha et al., 2011) Eno - l(1)G0004 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - mus209 experimental knowledge based (Guruharsha et al., 2011) Eno - ninaE anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - or anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Eno - porin experimental knowledge based (Guruharsha et al., 2011) Eno - regucalcin anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Eno - scf experimental knowledge based (Guruharsha et al., 2011) Eno - scu experimental knowledge based (Guruharsha et al., 2011) Eno - smt3 experimental knowledge based (Guruharsha et al., 2011) Eno - yip2 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Eno allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59591 DroID - A comprehensive database of gene and protein interactions. • FBgn0000579 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33351
Orthologs
OrthoDB Orthologs (68) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG62V922 Dipteran inclusive ortholog search EOG63N7N7 Insect inclusive ortholog search EOG6M384Z Arthropod inclusive ortholog search EOG6QRFKD Metazoa inclusive ortholog search EOG6BS8D4
Orthologs in Drosophila Species (EOG62V922)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Eno     Drosophila simulans   Dsim\GD22899 Y   Drosophila sechellia   Dsec\GM16597 Y   Drosophila erecta   Dere\GG24579 Y   Drosophila yakuba   Dyak\GE15467 Y   Drosophila ananassae   Dana\GF15876 Y   Drosophila pseudoobscura pseudoobscura   Dpse\Eno Y   Drosophila persimilis   Dper\GL18473 Y   Drosophila willistoni   Dwil\GK18469 Y   Drosophila willistoni   Dwil\GK20200     Drosophila virilis   Dvir\GJ17449 Y   Drosophila mojavensis   Dmoj\GI13781 Y   Drosophila grimshawi   Dgri\GH25025 Y
Orthologs in non-Drosophila Dipterans (EOG63N7N7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001668   Anopheles gambiae Malaria mosquito  Agam\AGAP007827   Culex quinquefasciatus Southern house mosquito  Cqui\eno
Orthologs in non-Dipteran Insects (EOG6M384Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Ame.16855   Apis mellifera Western honey bee  Amel\GB54753   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012229   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17350   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17006   Atta cephalotes Leafcutter ant  Acep\eno   Atta cephalotes Leafcutter ant  Acep\ACEP15070   Camponotus floridanus Florida carpenter ant  Cflo\eno   Harpegnathos saltator Jerdons jumping ant  Hsal\eno   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20780   Linepithema humile Argentine ant  Lhum\LH11866   Linepithema humile Argentine ant  Lhum\LH10878   Pogonomyrmex barbatus Red harvester ant  Pbar\PB24775   Solenopsis invicta Red fire ant  Sinv\SINV20495   Acyrthosiphon pisum Pea aphid  Apim\ACYPI005806   Bombyx mori Silkmoth  Bmor\BGIBMGA002337   Bombyx mori Silkmoth  Bmor\BGIBMGA005493   Pediculus humanus Human body louse  Phum\PHUM466290   Tribolium castaneum Red flour beetle  Tcas\TC011729   Tribolium castaneum Red flour beetle  Tcas\TC011730   Tribolium castaneum Red flour beetle  Tcas\TC012754
Orthologs in non-Insect Arthropods (EOG6QRFKD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\ENO   Ixodes scapularis Deer tick  Isca\ISCW017666
Orthologs in non-Arthropod Metazoa (EOG6BS8D4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\enol-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013819gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013820gn   Danio rerio Zebrafish  Drer\ENSDARG00000013750   Danio rerio Zebrafish  Drer\eno1   Danio rerio Zebrafish  Drer\eno3   Danio rerio Zebrafish  Drer\eno2   Xenopus tropicalis Western clawed frog  Xtro\eno1   Gallus gallus Domestic chicken  Ggal\ENO1   Gallus gallus Domestic chicken  Ggal\ENO2   Mus musculus House mouse  Mmus\Eno1   Mus musculus House mouse  Mmus\Eno1   Mus musculus House mouse  Mmus\Eno3   Rattus norvegicus Norway rat  Rnor\Eno2   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038934   Rattus norvegicus Norway rat  Rnor\Eno3   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000028678   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031122   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000026617   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000001512   Rattus norvegicus Norway rat  Rnor\Eno1   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024875   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042272   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000001511   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000026410   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031737   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000025066   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000017461   Homo sapiens Human  Hsap\ENO1
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENO1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22899 Drosophila sechellia Dsec\GM16597 Drosophila erecta Dere\GG24579 Drosophila yakuba Dyak\GE15467 Drosophila ananassae Dana\GF15876 Drosophila pseudoobscura pseudoobscura Dpse\Eno Drosophila persimilis Dper\GL18473 Drosophila willistoni Dwil\GK18469 Drosophila virilis Dvir\GJ17449 Drosophila mojavensis Dmoj\GI13781 Drosophila grimshawi Dgri\GH25025
Stocks & Reagents
Stocks Listed in FlyBase ( 16 )
Bloomington	26300 y1 v1; P{TRiP.JF02070}attP2 17972 w1118; PBac{RB}Enoe01615/CyO 19078 w1118; PBac{WH}Enof07543/CyO 19899 y1 w67c23; P{EPgy2}EnoEY02251 22610 y1 w67c23; P{EPgy2}EnoEY23161 13701 y1 w67c23; P{SUPor-P}EnoKG01162
Harvard	- P{XP}Enod07810 - PBac{RB}Enoe01615 - PBac{WH}Enof07543
Kyoto	124392 w1118; P{RS3}EnoUM-8172-3 126281 w1118; P{RS5}Eno5-SZ-4004 104167 w*; P{GawB}EnoNP2353 / CyO
	More stocks available...
Genomic Clones ( 2 )
	BACR19B15 BACR25P15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 300 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT25373 IP08721 SD23356
Other clones	FI05715 MIP03217
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04847 AT05850 AT08410 AT08528 AT12388 AT13660 AT14073 AT14893 AT20505 AT21775 AT22547 AT25277 AT28139 AT28152 GH01905 GH02013 GH02113 GH04012 GH05058 GH06601 GH06678 GH06850 GH06873 GH06950 GH06973 GH07638 GH09305 GH09636 GH09865 GH09965 GH10343 GH11410 GH11678 GH12409 GH12803 GH12917 GH14840 GH17417 GH17492 GH17759 GH18607 GH18753 GH18773 GH20031 GH20273 GH20423 GH20721 GH21690 GH21723 GH22053 GH22055 GH22281 GH23337 GH23856 GH24175 GH24219 GH24387 GH25230 GH25927 GH26611 GH27507 GH28386 GH28408 GH28435 GM01207 GM04437 GM09017 GM12258 GM17004 GM23027 GM23150 GM23705 GM25685 HL02137 HL03220 HL03358 HL07470 LD05070 LD06906 LD15163 LD15491 LD16995 LD17417 LD19046 LD20244 LD22205 LD30363 LD31958 LD35687 LD36480 LD36594 LD39688 LD39889 LD43772 LD44785 LP01639 LP03387 LP04982 LP06592 LP08769 LP08957 LP09411 LP10635 LP11416 LP12681 LP13890 LP17906 LP18988 LP19892 LP20431 LP21761 LP23856 RE30761 RE35026 RE35254 RE37044 RE41075 RE66270 RE69330 RE69384 RE69673 RE71511 RH02806 RH03487 RH31745 RH34486 RH56489 RH60323 RH62723 RH63727 RH70659 SD02670 SD04260 SD04518 SD11934 SD12670 SD13306 SD15262 SD16674 SD16941 SD17340 SD17621 SD18373 SD19587 SD19627 SD22060 SD22583 SD23715 SD26370 SD26564 SD27355
Other clones	bs05b02 bs20b04 bs22d06 bs50e01 bs56b05 bs61d03 bs85f09 Dmel_dig_000775_0640_3657 Dmel_dig_002681_0692_3511 Dmel_dig_002798_0594_1396 Dmel_dig_004082_0612_2012 Dmel_dig_004780_0643_2732 Dmel_dig_005437_0663_3619 Dmel_dig_006380_0663_3122 Dmel_dig_008190_0631_1630 Dmel_dig_009288_0677_3377 Dmel_dig_011631_0702_3717 Dmel_dig_012169_0704_2896 Dmel_dig_013123_0617_2925 Dmel_dig_013544_0588_3284 Dmel_dig_015889_0674_2133 Dmel_dig_016401_0620_1880 Dmel_dig_016729_0642_1209 Dmel_neb_000533_0871_3683 Dmel_neb_005278_0686_2098 Dmel_neb_005504_0683_1568 Dmel_neb_008012_0935_3088 Dmel_neb_008640_0936_2599 Dmel_neb_009613_0835_1196 Dmel_neb_010281_0147_0441 Dmel_neb_011304_0316_3305 Dmel_neb_011629_0371_2658 Dmel_neb_013341_0933_2851 Dmel_neb_013385_0700_2628 Dmel_neb_013490_0889_0565 Dmel_neb_013500_0124_2821 Dmel_neb_013942_0168_2906 Dmel_neb_014787_0830_1649 Dmel_neb_014799_0413_3114 Dmel_neb_015498_0380_1685 EK103006 EK114057 EK153227 EK155616 EK180246 EK185319 EK213822 EK222453 EK223003 EK241126 EK248743 EK250001 EK295019 EN04054 EN04847 EN08063 EN09057 EN13043 GH01942 GH16480 GH19632 GH23267 IP03463 IP04437 IP08349 IP13336 LD15431 LD17588 LD32708 LD38628 LP16539 LP19093 RE02544 RE04175 RE04245 RE05122 RE05130 RE06133 RE07339 RE07823 RE07859 RE08692 RE14491 RE14557 RE15211 RE15253 RE16055 RE16665 RE16883 RE18342 RE20640 RE21705 RE23643 RE24101 RE27702 RE28001 RE31856 RE32138 RE33930 RE40451 RE40925 RE41082 RE41922 RE46231 RE46436 RE46503 RE48308 RE49338 RE51238 RE53178 RE53810 RE53949 RE58160 RE66030 RE67242 RE71977 RE74910 RH02539 RH13422 RH15426 RH17914 RH17987 RH27081 RH45429 RH50416 RH62874 RH63527 RH64480 RH72414 RP004200633 RP004212228 RP004221764 RP004234271 RP004249440 RP004259425 RP004352518 RP004384143 RP004424440 RP004459820 UT01391 UUGC0147 UUGC0428 UUGC0719 UUGC1017
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0000579 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33351
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Eno anon-WO0153538.76 (FlyBase, 1996-) Source for merge of: Eno BEST:LD15491 (Rana, 2004.7.8)
Additional comments	Source for merge of Eno anon-WO0153538.76 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Identified in 2D gels of CMW W2 wing imaginal disc cell proteins. (Santaren et al., 1993) Structural gene for enolase (2-phospho-D-glycerate hydrolase).
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_058073 NM_164431 NM_164432 NM_164433 NM_164434 NM_001169382 RefSeq (Proteins) • NP_477421 NP_722721 NP_722722 NP_722723 NP_722724 NP_001162853 DDBJ / EMBL / GenBank • AA440644 AAF51344 AAM48478 AAN10455 AAN10456 AAN10457 AAN10458 AC003945 AC004442 ACZ94145 AI388023 AI944753 AX201692 AY118449 BE662073 BH759283 BI640480 CAA34895 CL632133 CZ475931 CZ476946 L80125 X17034 Entrez Gene - A searchable database of RefSeq genes. • 33351 UniProtKB/Swiss-Prot • P15007 UniProtKB/TrEMBL • E1JHR5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Enolase (IPR000941) Enolase, conserved site (IPR020809) Enolase, C-terminal (IPR020810) Enolase, N-terminal (IPR020811)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59591 DroID - A comprehensive database of gene and protein interactions. • FBgn0000579 DRSC - Results from RNAi screens. • FBgn0000579 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0000579 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17654-RB;CG31287-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0000579 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33351 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33351 modMine - Data generated by the modENCODE project. • FBgn0000579
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	anon-WO0153538.76   BEST:LD15491   CG17654 (Nakahara et al., 2005, Karlsson et al., 2004, Vierstraete et al., 2004, Pile et al., 2003, Vierstraete et al., 2003, Terhzaz et al., 2006, Thornton et al., 2010, Perkins et al., 2009.3.31, Sun et al., 2011, Keleman et al., 2009.8.5, Reumer et al., 2009, Cammarato et al., 2011, Ni et al., 2010.12.1) CT32526 (Xie and Ding, 2000) Eno (Beller et al., 2006, Flowers et al., 2007, Buszczak et al., 2007, Dorus et al., 2006, Kallappagoudar et al., 2010, Liu and Lehmann, 2008, Wasbrough et al., 2010, Reumer et al., 2009, Franco et al., 2011, Japanese National Institute of Genetics, 2012.5.21) eno (Terhzaz et al., 2006) Eno2 (Harr and Schlotterer, 2000) ENOA (Mushegian et al., 1998) T18 (Vierstraete et al., 2004)
Name Synonym	Enolase (Cho et al., 2005, Lindsay et al., 2008, Anholt and Williams, 2010, Robinson et al., 2010, Reumer et al., 2009, Cammarato et al., 2011, Felix et al., 2012) enolase (Sun et al., 2011) phosphopyruvate hydratase (Zhang et al., 2004)
Secondary FlyBase IDs
	FBgn0045789 FBgn0045874
References ( 72 )
Generate a list of	All references relating to this gene ( 72 )
List References by type	Research paper  ( 37 ) Supplementary material  ( 10 ) Personal communication to FlyBase  ( 15 ) Abstract  ( 1 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Protein sequence record  ( 1 ) Curated genome annotation  ( 1 ) Patent  ( 1 ) Letter  ( 1 ) Book  ( 1 )
Recent research papers ( 4 )
	Crawford et al., 2012, Cell Death Differ. 19(12): 2040--2048 Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. [FBrf0220233] Felix et al., 2012, Genetics 191(3): 989--1002 Age-Specific Variation in Immune Response in Drosophila melanogaster Has a Genetic Basis. [FBrf0218944] Franco et al., 2011, Mol. Cell. Proteomics 10(5): M110.002188 A Novel Strategy to Isolate Ubiquitin Conjugates Reveals Wide Role for Ubiquitination during Neural Development. [FBrf0213919] Sun et al., 2011, PLoS ONE 6(4): e18215 Systems-scale analysis reveals pathways involved in cellular response to methamphetamine. [FBrf0213560] Show all research papers ...