FB2020_06, released Dec 22, 2020

Gene: Dmel\Est-P

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General Information
Symbol
Dmel\Est-P
Species
D. melanogaster
Name
Esterase P
Annotation Symbol
CG17148
Feature Type
protein_coding_gene
FlyBase ID
FBgn0000594
Gene Model Status
Current
Stock Availability
3 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Also Known As

yEst-6, ΨEst-6, EstP, Est-7

Key Links
Genomic Location
Cytogenetic map
69A1-69A1
Sequence location
3L:12,190,733..12,192,528 [+]
Recombination map

3-38

RefSeq locus
NT_037436 REGION:12190733..12192528
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (2 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables carboxylic ester hydrolase activity
inferred from direct assay
(Dumancic et al., 1997)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in extracellular space
inferred from biological aspect of ancestor with PANTHER:PTN000168732
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the type-B carboxylesterase/lipase family. (P18167)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
OTHER CARBOXYLESTERASES -
OTHER CARBOXYLESTERASES are carboxylesterases that do not fall into any other major carboxylesterase group.
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Est-P for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Est-P-RA
FBtr0076004
NM_176323
1740
544
Additional Transcript Data and Comments
Reported size (kB)

1.92, 1.25 (northern blot)

(Collet et al., 1990)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Est-P-PA
FBpp0075736
61.1
544
6.79
NP_788501
AAF49945
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

544 (aa)

(Collet et al., 1990)
Comments
External Data
Subunit Structure (UniProtKB)

Monomer.

(UniProt, P18167)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Est-P using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
(Collet et al., 1990)
third instar larval stage
organism
(Collet et al., 1990)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Est-P in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 29 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Est-P
Transgenic constructs containing regulatory region of Est-P
Deletions and Duplications ( 1 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (19)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\CES1
6 of 15
Yes
No
Hsap\CES3
6 of 15
Yes
Yes
Hsap\CES4A
6 of 15
Yes
No
Hsap\CES5A
6 of 15
Yes
Yes
Hsap\CES2
5 of 15
No
No
Hsap\ACHE
4 of 15
No
No
1  
Hsap\BCHE
3 of 15
No
No
1  
Hsap\CEL
3 of 15
No
No
Hsap\NLGN1
3 of 15
No
No
1  
Hsap\NLGN2
3 of 15
No
No
Hsap\NLGN3
3 of 15
No
No
Hsap\NLGN4X
3 of 15
No
No
Hsap\TG
3 of 15
No
No
Hsap\LOC107987423
2 of 15
No
Yes
Hsap\NLGN4Y
2 of 15
No
No
Hsap\CD74
1 of 15
No
Yes
Hsap\CES1P1
1 of 15
No
Yes
Hsap\NID1
1 of 15
No
No
Hsap\NID2
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (33)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Ces1a
6 of 15
Yes
Yes
Mmus\Ces1b
6 of 15
Yes
Yes
Mmus\Ces1c
6 of 15
Yes
Yes
Mmus\Ces1d
6 of 15
Yes
Yes
Mmus\Ces1e
6 of 15
Yes
No
Mmus\Ces1g
6 of 15
Yes
Yes
Mmus\Ces3a
6 of 15
Yes
Yes
Mmus\Ces3b
6 of 15
Yes
Yes
Mmus\Ces5a
6 of 15
Yes
Yes
Mmus\Ces1f
5 of 15
No
Yes
Mmus\Ces1h
5 of 15
No
No
Mmus\Ces2a
5 of 15
No
No
Mmus\Ces2b
5 of 15
No
No
Mmus\Ces2e
5 of 15
No
No
Mmus\Ces2f
5 of 15
No
No
Mmus\Ces2g
5 of 15
No
No
Mmus\Ces2h
5 of 15
No
No
Mmus\Ces4a
5 of 15
No
Yes
Mmus\Ache
4 of 15
No
No
Mmus\Ces2c
4 of 15
No
No
Mmus\Bche
3 of 15
No
No
Mmus\Nlgn1
3 of 15
No
No
Mmus\Nlgn2
3 of 15
No
No
Mmus\Nlgn3
3 of 15
No
No
Mmus\Tg
3 of 15
No
No
Mmus\Cel
2 of 15
No
No
Mmus\Adck5
1 of 15
No
No
Mmus\Cd74
1 of 15
No
Yes
Mmus\Clspn
1 of 15
No
No
Mmus\Gm2399
1 of 15
No
Yes
Mmus\Nid1
1 of 15
No
No
Mmus\Nid2
1 of 15
No
No
Mmus\Plekhg5
1 of 15
No
No
Rattus norvegicus (Norway rat) (37)
Rnor\Ces1a
6 of 13
Yes
No
Rnor\Ces1f
6 of 13
Yes
No
Rnor\Ces4a
6 of 13
Yes
No
Rnor\Ces5a
6 of 13
Yes
No
Rnor\Ces1c
5 of 13
No
No
Rnor\Ces1d
5 of 13
No
Yes
Rnor\Ces2g
5 of 13
No
No
Rnor\Ces2h
5 of 13
No
No
Rnor\Ces2i
5 of 13
No
No
Rnor\Ces2a
4 of 13
No
No
Rnor\Ces2e
4 of 13
No
No
Rnor\Ces2j
4 of 13
No
No
Rnor\LOC679149
4 of 13
No
No
Rnor\Bche
3 of 13
No
No
Rnor\Cel
3 of 13
No
No
Rnor\Ces1e
3 of 13
No
No
Rnor\Ces2c
3 of 13
No
No
Rnor\Ces2
3 of 13
No
No
Rnor\Cesl1
3 of 13
No
Yes
Rnor\LOC100910040
3 of 13
No
No
Rnor\Nlgn2
3 of 13
No
No
Rnor\Nlgn3
3 of 13
No
No
Rnor\Tg
3 of 13
No
Yes
Rnor\Ache
2 of 13
No
No
Rnor\Ces3a
2 of 13
No
Yes
Rnor\LOC688542
2 of 13
No
Yes
Rnor\LOC102548129
2 of 13
No
Yes
Rnor\Nlgn1
2 of 13
No
No
Rnor\Cd74
1 of 13
No
Yes
Rnor\LOC291863
1 of 13
No
Yes
Rnor\LOC679356
1 of 13
No
Yes
Rnor\LOC679368
1 of 13
No
Yes
Rnor\LOC100365112
1 of 13
No
Yes
Rnor\LOC102557406
1 of 13
No
Yes
Rnor\LOC108348093
1 of 13
No
Yes
Rnor\Nid1
1 of 13
No
No
Rnor\Nid2
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (22)
Xtro\ache
4 of 12
Yes
No
Xtro\ces2
4 of 12
Yes
No
Xtro\ces3
4 of 12
Yes
No
Xtro\LOC100494782
4 of 12
Yes
No
Xtro\bche
3 of 12
No
No
Xtro\cel
3 of 12
No
No
Xtro\nlgn2
3 of 12
No
No
Xtro\nlgn3
3 of 12
No
No
Xtro\nlgn4x
3 of 12
No
No
Xtro\tg
3 of 12
No
Yes
Xtro\bche
2 of 12
No
No
Xtro\ces1
2 of 12
No
Yes
Xtro\ces5a
2 of 12
No
Yes
Xtro\LOC100493652
2 of 12
No
Yes
Xtro\LOC100493819
2 of 12
No
Yes
Xtro\LOC100493994
2 of 12
No
Yes
Xtro\LOC100494295
2 of 12
No
Yes
Xtro\cd74
1 of 12
No
Yes
Xtro\LOC100492444
1 of 12
No
Yes
Xtro\nid1
1 of 12
No
No
Xtro\nid2
1 of 12
No
No
Xtro\nlgn1
1 of 12
No
No
Danio rerio (Zebrafish) (21)
Drer\ces2
6 of 15
Yes
No
Drer\ces3
6 of 15
Yes
Yes
Drer\si:ch211-93f2.1
5 of 15
No
Yes
Drer\ache
4 of 15
No
No
Drer\LOC100334697
4 of 15
No
No
Drer\si:dkey-30c15.17
4 of 15
No
Yes
Drer\cel.1
3 of 15
No
No
Drer\cel.2
3 of 15
No
No
Drer\nlgn1
3 of 15
No
No
Drer\nlgn2a
3 of 15
No
No
Drer\nlgn2b
3 of 15
No
No
Drer\nlgn3a
3 of 15
No
No
Drer\nlgn3b
3 of 15
No
No
Drer\nlgn4xa
3 of 15
No
No
Drer\nlgn4xb
3 of 15
No
No
Drer\si:ch211-71n6.4
3 of 15
No
No
Drer\tg
3 of 15
No
Yes
Drer\cd74a
1 of 15
No
Yes
Drer\nid1a
1 of 15
No
No
Drer\nid2a
1 of 15
No
No
Drer\si:dkey-193c22.1
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (47)
Cele\B0238.1
6 of 15
Yes
No
Cele\C52A10.1
6 of 15
Yes
No
Cele\C52A10.2
6 of 15
Yes
No
Cele\F15A8.6
6 of 15
Yes
No
Cele\F56C11.6
6 of 15
Yes
No
Cele\B0238.7
5 of 15
No
No
Cele\cest-1
5 of 15
No
No
Cele\F07C4.12
5 of 15
No
No
Cele\F13H6.3
5 of 15
No
No
Cele\ges-1
5 of 15
No
No
Cele\K07C11.4
5 of 15
No
No
Cele\K11G9.1
5 of 15
No
No
Cele\K11G9.2
5 of 15
No
No
Cele\K11G9.3
5 of 15
No
No
Cele\R173.3
5 of 15
No
No
Cele\T02B5.3
5 of 15
No
No
Cele\T07H6.1
5 of 15
No
No
Cele\T28C12.4
5 of 15
No
No
Cele\Y71H2AM.13
5 of 15
No
No
Cele\ZC376.1
5 of 15
No
No
Cele\ZC376.2
5 of 15
No
No
Cele\ZC376.3
5 of 15
No
No
Cele\ace-3
4 of 15
No
No
Cele\ace-4
4 of 15
No
No
Cele\C01B10.4
4 of 15
No
No
Cele\C01B10.10
4 of 15
No
No
Cele\C23H4.3
4 of 15
No
No
Cele\C23H4.7
4 of 15
No
No
Cele\C42D4.2
4 of 15
No
No
Cele\F55F3.2
4 of 15
No
Yes
Cele\T22D1.11
4 of 15
No
No
Cele\W02B12.4
4 of 15
No
No
Cele\ace-1
3 of 15
No
No
Cele\ace-2
3 of 15
No
No
Cele\C17H12.4
3 of 15
No
No
Cele\C23H4.2
3 of 15
No
No
Cele\C23H4.4
3 of 15
No
No
Cele\E01G6.3
3 of 15
No
No
Cele\glit-1
3 of 15
No
No
Cele\B0238.13
2 of 15
No
No
Cele\nlg-1
2 of 15
No
No
Cele\T28C12.5
2 of 15
No
No
Cele\Y75B8A.3
2 of 15
No
No
Cele\ZK994.1
2 of 15
No
No
Cele\F13H6.4
1 of 15
No
No
Cele\nid-1
1 of 15
No
No
Cele\Y71G12B.28
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPCC417.12
3 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091905G3 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00004134
Drosophila simulans
Dsim\Est-P
Drosophila simulans
Dsim\Est-6
Drosophila sechellia
Dsec\Est-P
Drosophila sechellia
Dsec\Est-6
Drosophila erecta
Dere\Est-P
Drosophila erecta
Dere\Est-6
Drosophila yakuba
Dyak\Est-7
Drosophila yakuba
Dyak\GE21892
Drosophila ananassae
Dana\GF20094
Drosophila pseudoobscura pseudoobscura
Dpse\Est-5C
Drosophila pseudoobscura pseudoobscura
Dpse\Est-5B
Drosophila persimilis
Dper\Est-5A
Drosophila persimilis
Dper\Est-5C
Drosophila persimilis
Dper\Est-5B
Drosophila willistoni
Dwil\GK25474
Drosophila virilis
Dvir\GJ10073
Drosophila virilis
Dvir\GJ10072
Drosophila virilis
Dvir\GJ10074
Drosophila virilis
Dvir\GJ10075
Drosophila mojavensis
Dmoj\GI22473
Drosophila mojavensis
Dmoj\GI22474
Drosophila mojavensis
Dmoj\GI22471
Drosophila mojavensis
Dmoj\GI22476
Drosophila grimshawi
Dgri\GH15533
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150318 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17023145
Musca domestica
House fly
Mdoa\17023146
Musca domestica
House fly
Mdoa\17017326
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_07317
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02T5 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG017702
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (36)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Est-6
7 of 10
CG4382
6 of 10
CG4757
6 of 10
Jhedup
6 of 10
Jhe
6 of 10
α-Est1
5 of 10
α-Est2
5 of 10
α-Est4
5 of 10
α-Est5
5 of 10
α-Est6
5 of 10
α-Est7
5 of 10
α-Est9
5 of 10
CG3841
5 of 10
CG6414
5 of 10
CG9287
5 of 10
CG10175
5 of 10
clt
5 of 10
gas
5 of 10
Ace
4 of 10
α-Est3
4 of 10
α-Est8
4 of 10
α-Est10
4 of 10
CG5397
4 of 10
CG9289
4 of 10
CG12869
4 of 10
Est-Q
4 of 10
Glt
4 of 10
Nrt
4 of 10
CG10339
3 of 10
Gli
3 of 10
Nlg3
3 of 10
Nlg1
2 of 10
Nlg2
2 of 10
Nlg4
2 of 10
CG30095
1 of 10
Ndg
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CES1; carboxylesterase 1
    6 of 15
    114835
      CES3; carboxylesterase 3
      6 of 15
      605279
          CES4A; carboxylesterase 4A
          6 of 15
              CES5A; carboxylesterase 5A
              6 of 15
              618678
                  CES2; carboxylesterase 2
                  5 of 15
                  605278
                      ACHE; acetylcholinesterase (Cartwright blood group)
                      4 of 15
                      100740
                         
                        BCHE; butyrylcholinesterase
                        3 of 15
                        177400
                           
                          CEL; carboxyl ester lipase
                          3 of 15
                          114840
                          NLGN1; neuroligin 1
                          3 of 15
                          600568
                             
                            NLGN2; neuroligin 2
                            3 of 15
                            606479
                                NLGN3; neuroligin 3
                                3 of 15
                                300336
                                  NLGN4X; neuroligin 4 X-linked
                                  3 of 15
                                  300427
                                    TG; thyroglobulin
                                    3 of 15
                                    188450
                                      Functional Complementation Data
                                      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                      Interactions
                                      Summary of Physical Interactions
                                      esyN Network Diagram
                                      Interactions Browser
                                      Summary of Genetic Interactions
                                      esyN Network Diagram
                                      Starting gene(s)
                                      Interaction type
                                      Interacting gene(s)
                                      Reference
                                      Starting gene(s)
                                      Interaction type
                                      Interacting gene(s)
                                      Reference
                                      External Data
                                      Subunit Structure (UniProtKB)
                                      Monomer.
                                      (UniProt, P18167 )
                                      Linkouts
                                      DroID - A comprehensive database of gene and protein interactions.
                                      Pathways
                                      Signaling Pathways (FlyBase)
                                      Metabolic Pathways
                                      External Data
                                      Linkouts
                                      KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                      Genomic Location and Detailed Mapping Data
                                      Chromosome (arm)
                                      3L
                                      Recombination map

                                      3-38

                                      Cytogenetic map
                                      69A1-69A1
                                      Sequence location
                                      3L:12,190,733..12,192,528 [+]
                                      FlyBase Computed Cytological Location
                                      Cytogenetic map
                                      Evidence for location
                                      69A1-69A1
                                      Limits computationally determined from genome sequence between P{PZ}rols08232&P{lacW}l(3)j2D3j2D3 and P{PZ}l(3)0508805088
                                      Experimentally Determined Cytological Location
                                      Cytogenetic map
                                      Notes
                                      References
                                      69A-69A
                                      (determined by in situ hybridisation)
                                      (Segarra et al., 1996)
                                      69A1-69A1
                                      (determined by in situ hybridisation)
                                      (Oakeshott et al., 1993)
                                      Experimentally Determined Recombination Data
                                      Location

                                      3-38

                                      (FlyBase, 2016)

                                      3-30.9

                                      (Comeron et al., 2012)

                                      3-35.9

                                      Left of (cM)
                                      Right of (cM)
                                      Notes
                                      Stocks and Reagents
                                      Stocks (3)
                                      Genomic Clones (13)
                                       

                                      Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                      cDNA Clones (2)
                                       

                                      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                      cDNA clones, fully sequenced
                                      BDGP DGC clones
                                      Other clones
                                      Drosophila Genomics Resource Center cDNA clones

                                      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                      cDNA Clones, End Sequenced (ESTs)
                                      BDGP DGC clones
                                        Other clones
                                          RNAi and Array Information
                                          Linkouts
                                          DRSC - Results frm RNAi screens
                                          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                          Antibody Information
                                          Laboratory Generated Antibodies
                                           
                                          Commercially Available Antibodies
                                           
                                          Other Information
                                          Relationship to Other Genes
                                          Source for database identify of

                                          Source for identity of: Est-P CG17148

                                          (Li, 1999.11)
                                          Source for database merge of
                                          Additional comments
                                          Other Comments

                                          The more recently acquired site of Est-6 activity, the anterior ejaculatory duct, is directed by distal sequences lying both 5' and 3' of the coding region. The 3' sequences appear to lie within the transcription unit of the adjacent Est-P gene.

                                          (Healy et al., 1996)

                                          Chromosome homologies of Muller's element D (J chromosome in the Paleartic species and XR chromosome arm in Nearctic species) and of element E (O chromosome in the Paleartic species and 2 chromosome in Nearctic species) have been confirmed by single copy probes in the species of the obscura group and in D.melanogaster.

                                          (Segarra et al., 1996)

                                          The sequences of the Dpse\Est-5A, Dpse\Est-5B and Dpse\Est-5C genes, and the D.melanogaster Est-6 and Est-P genes have been compared.

                                          (Brady and Richmond, 1992)

                                          The Est-6 and Est-P genes, which are arranged as a tandem repeat, have been cloned and sequenced.

                                          (Collet et al., 1990)
                                          Origin and Etymology
                                          Discoverer
                                          Etymology
                                          Identification
                                          External Crossreferences and Linkouts ( 106 )
                                          Sequence Crossreferences
                                          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                                          Other crossreferences
                                          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                          Flygut - An atlas of the Drosophila adult midgut
                                          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                          InterPro - A database of protein families, domains and functional sites
                                          KEGG Genes - Molecular building blocks of life in the genomic space.
                                          modMine - A data warehouse for the modENCODE project
                                          Linkouts
                                          DPiM - Drosophila Protein interaction map
                                          DroID - A comprehensive database of gene and protein interactions.
                                          DRSC - Results frm RNAi screens
                                          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                                          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                                          FlyMine - An integrated database for Drosophila genomics
                                          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                          Synonyms and Secondary IDs (15)
                                          Datasets (0)
                                          Study focus (0)
                                          Experimental Role
                                          Project
                                          Project Type
                                          Title
                                          References (78)