Gene model reviewed during 5.52
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fbp2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Fbp2 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Gene expression is increased in response to the presence of either one or two copies of Scer\GAL4hs.PB.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Reduced Fbp2 RNA levels in br mutants can be restored to wild type by transgenes bearing the Z1, Z2, Z3 or Z4 isoforms of BRC products.
The steroid hormone 20-hydroxyecdysone can regulate RNA levels of a single gene both positively and negatively depending on hormone concentration. br can modify the direction of the gene's response to a hormone signal.
Gene detected in the larval fat body of D.melanogaster. Function of the protein product uncertain (Deutch, Laval, Lepesant, Maschat, Pourrain and Rat, 1989).