A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\Fps85D

General Information
SymbolDmel\Fps85DSpeciesD. melanogaster
NameFps oncogene analogAnnotation symbolCG8874
Feature typeprotein_coding_geneFlyBase IDFBgn0000723
Gene Model StatusCurrent Stock availability 15 publicly available
Also Known AsFER, Dfer, dfps85D, FPS, DmHD-179, Dfps
Genomic Location
Chromosome (arm)3RRecombination map3-
Cytogenetic map85D13-85D15Sequence location3R:5,193,321..5,220,265 [-]

Genomic Maps

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modENCODE GBrowse
detailed view
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Automatically generated summary

See sections below for more information
The gene Fps oncogene analog is referred to in FlyBase by the symbol Dmel\Fps85D (CG8874, FBgn0000723). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process: dorsal closure, elongation of leading edge cells; dorsal closure; actin filament bundle assembly; axon guidance; photoreceptor cell morphogenesis; dorsal closure, amnioserosa morphology change. 19 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; amnioserosa; ventral midline. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Fps/Fes/Fer/CIP4 homology; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval trachea, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1639139_a_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of Fps85D. Gene sequence location is 3R:5193321..5220265.

External Summaries
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Description
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FB2012_01
Sequence features
FB2011_10
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
85D13-85D15  
Limits computationally determined from genome sequence between P{lacW}l(3)L4092L4092 and P{PZ}ps10615&P{PZ}Ras85D06677  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
85D10-85D13  
85D10-85D13  
(determined by in situ hybridisation)  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\Fps85D for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0082026 FBtr0082027 FBtr0082054 FBtr0082053 FBtr0082052 FBtr0082051 FBpp0081504 FBpp0081505 FBpp0081532 FBpp0081531 FBpp0081529 FBpp0081530 FBti0041147 FBti0044621 FBti0127442 FBti0052091 FBti0037780 FBti0069899 FBti0039168 FBti0054430 FBti0074341 FBti0016468 FBti0028334 FBti0070288 FBti0070651 FBti0057380 FBti0068893 FBti0036257 FBti0054215
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0082052
  4959
  1325
FBtr0082051
  3393
  804
FBtr0082053
  2837
  475
FBtr0082054
  2305
  393
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0081530  
150.3  
1325  
8.09  
FBpp0081529  
92.4  
804  
6.76  
FBpp0081531  
54.2  
475  
6.30  
FBpp0081532  
45.2  
393  
7.06  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
expression microarray
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG8129-RB CG8129-RA Fps85D-RD Fps85D-RC Fps85D-RA Fps85D-RB
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0000723


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0000723
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0000723 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 (601)
embryo 04-06hr
 (903)
embryo 06-08hr
 (1058)
embryo 08-10hr
 (1399)
embryo 10-12hr
 (1543)
embryo 12-14hr
 (1371)
embryo 14-16hr
 (1461)
embryo 16-18hr
 (1231)
embryo 18-20hr
 (900)
embryo 20-22hr
 (985)
embryo 22-24hr
 (1022)
larva L1
 (572)
larva L2
 (750)
larva L3 12hr old
 (653)
larva L3 puffstage 1-2
 (681)
larva L3 puffstage 3-6
 (1250)
larva L3 puffstage 7-9
 (1492)
white prepupae new
 (1300)
white prepupae 12hr
 (1776)
white prepupae 24hr
 (1671)
pupae 2d postWPP
 (1948)
pupae 3d postWPP
 (2086)
pupae 4d postWPP
 (1268)
adult male 01day
 (1585)
adult male 05day
 (1817)
adult male 30day
 (1752)
adult female 01day
 (819)
adult female 05day
 (384)
adult female 30day
 (337)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 (1543)
embryo 12-14hr
 
 1371
embryo 14-16hr
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 1492
white prepupae new
 
 1300
white prepupae 12hr
 (1776)
white prepupae 24hr
 (1671)
pupae 2d postWPP
 (1948)
pupae 3d postWPP
 (2086)
pupae 4d postWPP
 
 1268
adult male 01day
 (1585)
adult male 05day
 (1817)
adult male 30day
 (1752)
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0000723 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 (601)
embryo 04-06hr
 (903)
embryo 06-08hr
 (1058)
embryo 08-10hr
 (1399)
embryo 10-12hr
 (1543)
embryo 12-14hr
 (1371)
embryo 14-16hr
 (1461)
embryo 16-18hr
 (1231)
embryo 18-20hr
 (900)
embryo 20-22hr
 (985)
embryo 22-24hr
 (1022)
larva L1
 (572)
larva L2
 (750)
larva L3 12hr old
 (653)
larva L3 puffstage 1-2
 (681)
larva L3 puffstage 3-6
 (1250)
larva L3 puffstage 7-9
 (1492)
white prepupae new
 (1300)
white prepupae 12hr
 (1776)
white prepupae 24hr
 (1671)
pupae 2d postWPP
 (1948)
pupae 3d postWPP
 (2086)
pupae 4d postWPP
 (1268)
adult male 01day
 (1585)
adult male 05day
 (1817)
adult male 30day
 (1752)
adult female 01day
 (819)
adult female 05day
 (384)
adult female 30day
 (337)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 1492
white prepupae new
 
 1300
white prepupae 12hr
 1776
white prepupae 24hr
 1671
pupae 2d postWPP
 1948
pupae 3d postWPP
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 1585
adult male 05day
 1817
adult male 30day
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 38
embryo 02-04hr
 
 601
embryo 04-06hr
 
 903
embryo 06-08hr
 
 1058
embryo 08-10hr
 
 1399
embryo 10-12hr
 
 1543
embryo 12-14hr
 
 1371
embryo 14-16hr
 
 1461
embryo 16-18hr
 
 1231
embryo 18-20hr
 
 900
embryo 20-22hr
 
 985
embryo 22-24hr
 
 1022
larva L1
 
 572
larva L2
 
 750
larva L3 12hr old
 
 653
larva L3 puffstage 1-2
 
 681
larva L3 puffstage 3-6
 
 1250
larva L3 puffstage 7-9
 
 1492
white prepupae new
 
 1300
white prepupae 12hr
 
 1776
white prepupae 24hr
 
 1671
pupae 2d postWPP
 
 1948
pupae 3d postWPP
 
 2086
pupae 4d postWPP
 
 1268
adult male 01day
 
 1585
adult male 05day
 
 1817
adult male 30day
 
 1752
adult female 01day
 
 819
adult female 05day
 
 384
adult female 30day
 
 337
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0000723


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0000723
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval trachea, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0000723 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 (679.5)
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 (707.4)
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0000723 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 206.475
Larval Midgut
 
 227.9
Larval Hindgut
 
 350.4
Larval Malpighian Tubules
 
 370.5
Larval Fat Body
 
 63
Larval Salivary Gland
 
 61
Larval Trachea
 
 201.75
Larval Carcass
 
 439.7
Adult Head
 
 214.4
Adult Eye
 
 679.5
Adult Brain
 
 98.9
Adult Thoracic-Abdominal Ganglion
 
 128.9
Adult Crop
 
 707.4
Adult Midgut
 
 224.3
Adult Hindgut
 
 494.9
Adult Malpighian Tubules
 
 500.9
Adult Fat Body
 
 94.4
Adult Salivary Gland
 
 71.4
Adult Heart
 
 216.2
Adult VirginFemale Spermatheca
 
 75.5
Adult InseminatedFemale Spermatheca
 
 96.9
Adult Ovary
 
 19.8
Adult Testis
 
 35.5
Adult Male Accessory Gland
 
 134.5
Adult Carcass
 
 196.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 214.4
 
NA 
Eye
 
 679.5
 
NA 
Brain
 
 98.9
 
206.475 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 128.9
 
NA 
Crop
 
 707.4
 
227.9 
Midgut
 
 224.3
 
350.4 
Hindgut
 
 494.9
 
370.5 
Malpighian Tubules
 
 500.9
 
63 
Fat Body
 
 94.4
 
61 
Salivary Gland
 
 71.4
 
NA 
Heart
 
 216.2
 
201.75 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 75.5
 
NA 
InseminatedFemale Spermatheca
 
 96.9
 
NA 
Ovary
 
 19.8
 
NA 
Testis
 
 35.5
 
NA 
Male Accessory Gland
 
 134.5
 
439.7 
Carcass
 
 196.8

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Sterility
Allele
Phenotype manifest in
Allele
embryonic leading edge cell & actomyosin
embryonic leading edge cell & filopodium
hide Classical Alleles ( 8 )
For All Classical Alleles Show

Allele of Fps85DClassMutagenStocksKnown lesion
Fps85DE134
1 Yes
Fps85Df04954
1 --
Fps85DMB08538
1 --
Fps85DX21loss of function allele1 Yes
Fps85DX421 Yes
Fps85DB363
0 --
Fps85Dgofgain of function allele0 Yes
Fps85DΔex1hypomorphic allele - genetic evidence0 Yes
hide Alleles Carried on Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Fps85DClassMutagenStocksKnown lesion
Fps85DGD140542 Yes
Fps85DdsRNA.Scer\UAS1 Yes
Fps85DHMS002491 Yes
Fps85DKK1020221 Yes
Fps85Dp100.Scer\UAS1 Yes
Fps85Dp45.Scer\UAS1 Yes
Fps85Dp92.KM.Scer\UAS1 Yes
Fps85Dp92.Scer\UAS.T:Myr11 Yes
Fps85Dp92.Scer\UAS1 Yes
Fps85DAct5C.PG0 Yes
Fps85DRB.Scer\UAS0 Yes
hide Aneuploid Aberrations
Disrupted in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
characterization construct
Insertions
Type of insertions
Name
Expression data
insertion of enhancer trap binary system
insertion of enhancer trap
hide Gene Ontology: Function, Process & Cellular Component ( 13 unique terms )
hide Terms Based on Experimental Evidence ( 8 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
inferred from mutant phenotype
inferred from genetic interaction with Src42A
Cellular Component
CV term
References
inferred from direct assay
inferred from direct assay
hide Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term
References
inferred from sequence or structural similarity
inferred from sequence or structural similarity with UniProtKB:P00541
non-traceable author statement
Biological Process
CV term
References
Cellular Component
CV term
References
non-traceable author statement
non-traceable author statement
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
Fps85D allele
Gene
References
hide External Data
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 15 )
Bloomington
Harvard
VDRC
hide Genomic Clones ( 2 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 33 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for identity of: Fps85D CG8874
Source for database merge of
Additional comments
Identified by PCR fragment; relationship to other protein tyrosine kinase genes not known.
hide Other Comments
Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The 92kD and 45kD Fps85D protein isoforms can transform avian and rodent cells when expressed from retroviral vectors.
Phylogenetic analysis of the PTK family.
Isolated using an avian v-fps gene fragment as a probe.
Fps85D has been cloned, sequenced and its expression pattern analysed.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 21 )
Reported As
Symbol Synonym
fps85D
 
HD-179
 
Name Synonym
Fps oncogene analog
Secondary FlyBase IDs
  • FBgn0022798
hide References ( 54 )
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hide Recent research papers ( 1 )
Blanco et al., 2010, BMC Dev. Biol. 10: 94
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
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All reviews listed in FlyBase were published before 2010