Cdt1, l(2)k03308, l(2)51Ec, fs(2)PA77, fs(2)ltoPA77
Gene model reviewed during 5.43
Gene model reviewed during 5.50
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dup using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\dup in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the formation of compact chromatin when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a greater than three-fold increase in AttA activity in response to heat-killed E.coli after ecdysone treatment in S2 cells.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Homozygous embryos show dramatically reduced levels of DNA replication after the 15th S phase.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.
Embryonic lethal alleles show increased epithelial apoptosis, incomplete cuticle formation and cessation of post-blastoderm DNA replication. Female sterile alleles result in either failure of pronuclear fusion or arrest during early mitotic divisions.
Mutations at the fs(2)51Fa locus cause defects in midoogenesis.