A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\fw

General Information
SymbolDmel\fwSpeciesD. melanogaster
NamefurrowedAnnotation symbolCG1500
Feature typeprotein_coding_geneFlyBase IDFBgn0001083
Gene Model StatusCurrent Stock availability 15 publicly available
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map11A1-11A1Sequence locationX:11,886,948..11,897,943 [-]

Genomic Maps

GBrowse View Help
modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene furrowed is referred to in FlyBase by the symbol Dmel\fw (CG1500, FBgn0001083). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding. There is experimental evidence that it is involved in the biological process: sensory organ development; imaginal disc-derived wing morphogenesis. 31 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; peripheral nervous system; eo support cell; embryonic/larval anal pad; spiracle; acrostichal bristle; antennal segment; postalar bristle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: C-type lectin; C-type lectin fold; C-type lectin, conserved site; C-type lectin-like; Coagulation factor 5/8 C-terminal type domain; Complement control module; Fucolectin tachylectin-4 pentraxin-1; Galactose-binding domain-like; Sushi/SCR/CCP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval hindgut, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1630231_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of fw. Gene sequence location is X:11886948..11897943.

External Summaries
hide Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage
fw: furrowed
Eyes with vertical fold and furrows. Head and scutellum shortened. Bristles gnarled and shortened, especially the postscutellars. Best classification character is short, blunt notopleurals. RK2. Phenotype can become nearly wild type on inbreeding (Lefevre).
*fw2
Extreme fw. Female sterile. RK2A.
fw34e
Originally showed eye surface medium folded; bristles much gnarled. Schultz and Curry report that stock in 1940 showed gnarled bristles and eye small but no vertical fold. RK2.
fw49c
Eyes furrowed; distal portions of aristal branches hooked; wings divergent and often stringy; scutellar groove reduced. Bristles split, bent, and often erect; acrostichal hair pattern distributed with whorls and naked areas. Late hatching, poorly viable, and mostly sterile. fw49c/fw phenotypically intermediate but more like fw/fw than fw49c/fw49c. RK3.
fw59
Eyes rough and creased; facets irregular, 15% fewer than normal. Eyes browner than normal; pterine concentration reduced in the eyes and, except for isoxanthopterine, increased in testis sheath. Riboflavin accumulates in Malpighian tubules. Large bristles of head and thorax short, thick, angled, blunt, and occasionally reduced to stumps. Arista thick with contorted and supernumerary branches. Scutellum small with groove between it and thorax reduced. Hatchability and larval development normal; larval anal plates swollen and surrounded by melanotic halo. Melanotic anal region persists in pupa; pupa also has melanotic spots elsewhere that may result in nonpigmented areas on the imaginal integument. Extrusion of anterior and posterior spiracles in prepupa incomplete. Many fw59 flies die either after 24-30 hr of pupal development or at the time of eclosion. Fecundity of female reduced owing to reduced number of ovarioles. RK2.
fw60
Like fw59 but with lower penetrance and expressivity. RK2.
*fww: furrowed-weak
Affects only bristles, particularly the scutellars and postalars. Eyes normal. Normal fertility and viability. RK2.
fwwr: furrowed-wrinkled
Eye surface in folds. Some bristles shortened, thickened, or curved; many doubled and may be fused. Viability low. RK2.
hide Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01
Sequence features
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
11A1-11A1  
Limits computationally determined from genome sequence between P{EP}ATP7EP308 and P{EP}EP1451&P{EP}EP1629  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
11A4-11A4  
Experimentally Determined Recombination Data
Location
1-36.85
Left of (cM)
Right of (cM)
Notes
97 of 129 recombinants between m and fw ocurred distal to cac. 5 of 8 recombinants between cac and fw were distal to gd. 2 of 10 gd/fw recombinants were distal to tsg.
hide Gene Model & Products
Please see the GBrowse view of Dmel\fw for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0299570 FBtr0073581 FBtr0112806 FBtr0073580 FBpp0288845 FBpp0073425 FBpp0111718 FBpp0073424 FBti0015044 FBti0114792 FBti0071528 FBti0014467 FBti0015043 FBti0048899 FBti0067177 FBti0072041 FBti0014466 FBti0036376 FBti0037238 FBti0015675 FBti0055113 FBti0111128 FBti0007473 FBti0059495 FBti0037331 FBti0035753 FBti0033817 FBti0034108 FBti0111229 FBti0007459 FBti0035153 FBti0076933 FBti0107708 FBti0029590 FBti0110626 FBti0100167 FBti0029766 FBti0018794 FBti0056113 FBti0059416 FBti0034154 FBti0037343 FBti0033684 FBti0034976 FBti0037334 FBti0036752 FBti0035196 FBti0034580 FBti0071879 FBti0029688 FBti0033836 FBti0111219
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0073580
  4694
  1174
FBtr0112806
  3938
  755
Additional Transcript Data & Comments
Reported size (kB)
4.5, 4.0 (northern blot)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
fw-PA  
FBpp0073424  
128.1  
1174  
5.59  
fw-PB  
FBpp0111718  
82.2  
755  
5.28  
Additional Polypeptide Data & Comments
Reported size (kDa)
974 (aa); 110 (kD observed)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
fw transcript is expressed in all imaginal discs. In the eye imaginal disc, expression is strongest in the dorsal and ventral margins. In the wing disc, expression is higher in cells of the prospective dorsal and ventral wing surfaces, ventral pleura and the notum. All cells in the haltere, leg, antennal, labial, clypeo-labral, humeral and genital discs express fw. Lower levels of fw expression are also seen in parts of the digestive system, the proventriculus, the gastric caecae, and parts of the larval brain.
The 4.0 and 4.5 kb fw transcripts are detected in all developmental stages.
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
The pattern of fw protein expression closely matches that of fw transcript expression. fw protein accumulates in all imaginal discs, in the pattern seen for fw transcript. Additional strong staining is seen in posterior to the morphogenetic furrow in the eye disc. fw protein is also expressed in parts of the digestive system, the proventriculus, and the gastric caecae, as well as in the larval brain.
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG18130-RB CG18130-RA fw-RB fw-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0001083


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0001083
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0001083 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 (141)
embryo 10-12hr
 (1001)
embryo 12-14hr
 (1680)
embryo 14-16hr
 (3706)
embryo 16-18hr
 (1527)
embryo 18-20hr
 (707)
embryo 20-22hr
 (210)
embryo 22-24hr
 (239)
larva L1
 (599)
larva L2
 (1351)
larva L3 12hr old
 (779)
larva L3 puffstage 1-2
 (548)
larva L3 puffstage 3-6
 (696)
larva L3 puffstage 7-9
 (449)
white prepupae new
 (408)
white prepupae 12hr
 (1773)
white prepupae 24hr
 (976)
pupae 2d postWPP
 (4795)
pupae 3d postWPP
 (1561)
pupae 4d postWPP
 (596)
adult male 01day
 (404)
adult male 05day
 (186)
adult male 30day
 (169)
adult female 01day
 (320)
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 (1680)
embryo 14-16hr
 (3706)
embryo 16-18hr
 (1527)
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 (1773)
white prepupae 24hr
 
 976
pupae 2d postWPP
 (4795)
pupae 3d postWPP
 (1561)
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0001083 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 141
embryo 10-12hr
 (1001)
embryo 12-14hr
 (1680)
embryo 14-16hr
 (3706)
embryo 16-18hr
 (1527)
embryo 18-20hr
 (707)
embryo 20-22hr
 (210)
embryo 22-24hr
 (239)
larva L1
 (599)
larva L2
 (1351)
larva L3 12hr old
 (779)
larva L3 puffstage 1-2
 (548)
larva L3 puffstage 3-6
 (696)
larva L3 puffstage 7-9
 (449)
white prepupae new
 (408)
white prepupae 12hr
 (1773)
white prepupae 24hr
 (976)
pupae 2d postWPP
 (4795)
pupae 3d postWPP
 (1561)
pupae 4d postWPP
 (596)
adult male 01day
 (404)
adult male 05day
 (186)
adult male 30day
 (169)
adult female 01day
 (320)
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 1680
embryo 14-16hr
 (3706)
embryo 16-18hr
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 (4795)
pupae 3d postWPP
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 9
embryo 02-04hr
 
 65
embryo 04-06hr
 
 85
embryo 06-08hr
 
 96
embryo 08-10hr
 
 141
embryo 10-12hr
 
 1001
embryo 12-14hr
 
 1680
embryo 14-16hr
 
 3706
embryo 16-18hr
 
 1527
embryo 18-20hr
 
 707
embryo 20-22hr
 
 210
embryo 22-24hr
 
 239
larva L1
 
 599
larva L2
 
 1351
larva L3 12hr old
 
 779
larva L3 puffstage 1-2
 
 548
larva L3 puffstage 3-6
 
 696
larva L3 puffstage 7-9
 
 449
white prepupae new
 
 408
white prepupae 12hr
 
 1773
white prepupae 24hr
 
 976
pupae 2d postWPP
 
 4795
pupae 3d postWPP
 
 1561
pupae 4d postWPP
 
 596
adult male 01day
 
 404
adult male 05day
 
 186
adult male 30day
 
 169
adult female 01day
 
 320
adult female 05day
 
 28
adult female 30day
 
 27
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0001083


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0001083
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval hindgut, larval trachea.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0001083 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 (623.9)
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0001083 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 68.525
Larval Midgut
 
 7.4
Larval Hindgut
 
 461.7
Larval Malpighian Tubules
 
 7.7
Larval Fat Body
 
 5.7
Larval Salivary Gland no informative data
Larval Trachea
 
 453.85
Larval Carcass
 
 623.9
Adult Head
 
 55.8
Adult Eye
 
 187.425
Adult Brain
 
 7.9
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 33
Adult Midgut
 
 6.4
Adult Hindgut
 
 19.8
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 27.9
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 38.5
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 1.9
Adult Testis
 
 2.9
Adult Male Accessory Gland
 
 5.9
Adult Carcass
 
 44
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland no informative data
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion no informative data
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules no informative data
Adult Fat Body
 
 
Adult Salivary Gland no informative data
Adult Heart no informative data
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca no informative data
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 55.8
 
NA 
Eye
 
 187.425
 
NA 
Brain
 
 7.9
 
68.525 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 no informative data
 
NA 
Crop
 
 33
 
7.4 
Midgut
 
 6.4
 
461.7 
Hindgut
 
 19.8
 
7.7 
Malpighian Tubules
 
 no informative data
 
5.7 
Fat Body
 
 27.9
 
no informative data 
Salivary Gland
 
 no informative data
 
NA 
Heart
 
 no informative data
 
453.85 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 38.5
 
NA 
InseminatedFemale Spermatheca
 
 no informative data
 
NA 
Ovary
 
 1.9
 
NA 
Testis
 
 2.9
 
NA 
Male Accessory Gland
 
 5.9
 
623.9 
Carcass
 
 44

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
eye & macrochaeta
hide Classical Alleles ( 27 )
For All Classical Alleles Show

Allele of fwClassMutagenStocksKnown lesion
fw1hypomorphic allele - genetic evidence6 Yes
fw34ehypomorphic allele - genetic evidence2 Yes
fwe045642 --
fwe045281 --
fwG15221 --
fw20c
0 --
fw20 --
fw33d
0 --
fw33e
0 --
fw35k
0 --
fw39k
0 --
fw49c0 --
fw51g0 --
fw51h0 --
fw590 --
fw600 --
fw670 --
fw680 --
fwc
0 --
fwGEM
0 --
fwGG01530
0 --
fwH0 --
fwPOc2.10 Yes
fwU2hypomorphic allele - genetic evidence0 Yes
fwU30 Yes
fww0 --
fwwr0 --
hide Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show

Allele of fwClassMutagenStocksKnown lesion
fwGD33271 Yes
fwJF029381 Yes
fwKK1092001 Yes
fw+t12.70 Yes
hide Aneuploid Aberrations
Not disrupted in
Not duplicated in
Disrupted in
Duplicated in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
characterization construct
Insertions
Type of insertions
Name
Expression data
insertion of enhancer trap
insertion of enhancer trap binary system
insertion of mobile activating element
hide Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
hide Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term
References
Biological Process
CV term
References
inferred from electronic annotation with InterPro:IPR000421
Cellular Component ( 0 terms)
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
fw allele
Gene
References
hide External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 15 )
Bloomington
Harvard
Kyoto
105755
105764
105781
VDRC
hide Genomic Clones ( 2 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 17 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
hide Antibody Information
hide Other Information
hide Discoverer
Duncan, Nov. 1914.
 
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for identity of: fw CG1500
Source for database merge of
Additional comments
"l(1)G0214" may affect "fw".
hide Other Comments
fw mutational analysis suggests the product is necessary for viability and is involved in wing morphogenesis and cell determination events within sensory organs.
Eight new alleles of fw were generated in a screen for X-linked mutations affecting bristle morphology.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym
Name Synonym
wrinkled
Secondary FlyBase IDs
hide References ( 70 )
Generate a list of
List References by type
hide Recent research papers ( 1 )
Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784
GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834]
hide Recent reviews (0)
All reviews listed in FlyBase were published before 2010