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Gene Dmel\Gapdh1

General Information
Symbol	Dmel\Gapdh1	Species	D. melanogaster
Name	Glyceraldehyde 3 phosphate dehydrogenase 1	Annotation symbol	CG12055
Feature type	protein_coding_gene	FlyBase ID	FBgn0001091
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	Gapdh, GAPDH-1, GADPH
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43E17-43E17	Sequence location	2R:3,679,406..3,680,885 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Glyceraldehyde 3 phosphate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\Gapdh1 (CG12055, FBgn0001091). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. There is experimental evidence that it is involved in the biological process: glycolysis. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, active site; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde-3-phosphate dehydrogenase, type I; Glyceraldehyde/Erythrose phosphate dehydrogenase family; NAD(P)-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression. Peak expression observed at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1640907_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Gapdh1. Gene sequence location is 2R:3679406..3680885.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Gapdh1: Glyceraldehyde dehydrogenase 1 One of two genes (Gapdh1 and Gapdh2) that code for the enzyme glyceraldehyde-3-phosphate dehydrogenase [G3PD (EC.1.2.12)]. These genes are expressed in almost all cells, especially those that undergo a high rate of glycolysis.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43E17-43E17   Limits computationally determined from genome sequence between P{EP}CanB2EP774 and P{lacW}lin19k01207&P{lacW}rnh1k07624
Experimentally Determined Cytological Location
Cytogenetic map Notes References 43E-43F   (determined by in situ hybridisation)   (Tso et al., 1985) 43E-43E   (determined by in situ hybridisation)   (Sullivan et al., 1985)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Gapdh1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Gapdh1-RA FBtr0088903  NM_080369   1480   332 Gapdh1-RB FBtr0100479  NM_001038847   1330   332
Additional Transcript Data & Comments
Reported size (kB)	1.6 (northern blot) (Tso et al., 1985)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Gapdh1-PA   FBpp0087977   35.4   332   8.42     NP_525108   AAF59192 Gapdh1-PB   FBpp0099914   35.4   332   8.42     NP_001033936   ABC66066
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glyceraldehyde-3-phosphate dehydrogenase, type I (IPR006424) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (IPR020828) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (IPR020829) Glyceraldehyde 3-phosphate dehydrogenase, active site (IPR020830) Glyceraldehyde/Erythrose phosphate dehydrogenase family (IPR020831) NAD(P)-binding domain (IPR016040)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202964   AA536442   AA567112   AA567114   AA567116   AA695976   AA697257   AA697910   AA698025   AA699238   AA802195   AA802700   AA802993   AA803724   AA820539   AE013599 AAF59192   AE013599 ABC66066   AI062007   AI062698   AI063517   AI106785   AI107204   AI107763   AI108403   AI108825   AI109169   AI109485   AI109675   AI109746   AI109951   AI113529   AI113553   AI113745   AI114047   AI133956   AI134073   AI134095   AI134947   AI135275   AI238243   AI238412   AI238478   AI238682   AI238705   AI238775   AI256872   AI258487   AI259487   AI260033   AI292883   AI293428   AI293447   AI294426   AI295040   AI296623   AI297526   AI297599   AI386660   AI387022   AI387333   AI387511   AI387967   AI388464   AI388534   AI389205   AI402335   AI402420   AI402987   AI403789   AI403835   AI404267   AI404686   AI404903   AI405183   AI405842   AI455451   AI456280   AI456480   AI513205   AI513770   AI516612   AI516904   AI517858   AI518498   AI546601   AK284686   AY089643 AAL90381   AY094940   AY231704   AY441207   BF500796   BG632390   BG632702   BG632774   BG632930   BG633993   BG636296   BG640622   BI163260   BI164656   BI168817   BI171318   BI173332   BI173378   BI173828   BI214542   BI215916   BI227931   BI230796   BI233189   BI234862   BI234937   BI235061   BI235185   BI235885   BI236645   BI238498   BI240402   BI242168   BI242596   BI353219   BI353471   BI354479   BI355849   BI361396   BI367829   BI370974   BI372620   BI372633   BI372806   BI372961   BI481704   BI482539   BI483320   BI483601   BI484299   BI485399   BI485845   BI486075   BI564141   BI564647   BI564659   BI564756   BI565021   BI565168   BI565324   BI565360   BI565683   BI566438   BI567677   BI568316   BI568362   BI568464   BI569920   BI570062   BI570472   BI571662   BI571950   BI572831   BI573577   BI573578   BI574258   BI575024   BI575047   BI575798   BI575871   BI576423   BI576911   BI577425   BI579567   BI581511   BI581600   BI583459   BI583689   BI583991   BI584090   BI584094   BI584659   BI585566   BI586726   BI586754   BI586988   BI587072   BI588423   BI588439   BI588448   BI589145   BI589319   BI589742   BI590361   BI590987   BI592297   BI593256   BI604531   BI605164   BI605182   BI605587   BI605739   BI605975   BI606259   BI606372   BI606642   BI606759   BI607394   BI607602   BI609237   BI610362   BI610392   BI610747   BI611165   BI611507   BI611580   BI611610   BI612058   BI612266   BI613294   BI613956   BI614131   BI614705   BI615091   BI615203   BI615241   BI615569   BI615570   BI615592   BI615701   BI615978   BI616479   BI616580   BI616695   BI617213   BI617809   BI618556   BI618889   BI619032   BI619533   BI619676   BI620188   BI620355   BI621342   BI621900   BI622147   BI623006   BI623235   BI623381   BI624364   BI624780   BI625006   BI625448   BI626472   BI627271   BI627705   BI628866   BI628922   BI630774   BI630794   BI631194   BI631214   BI631254   BI632798   BI633059   BI634292   BI634301   BI634807   BI634876   BI635468   BQ103054   BT004485 AAO42649   BX008333   BX012207   BX014553   BX015882   BX015886   BX031723   BX032235   BX032633   BX033087   BX033362   BX034622   BX052014   BX057023   BX057309   BX061482   BX066162   BX068467   CK135234   CK445288   CK605320   CK605321   CO153849   CO183555   CO284636   CO312933   CO332837   CO335600   CO336510   CO338109   EC060963   EC063378   EC065092   EC067865   EC206034   EC264591   EC265091   EC267096   EC267719   EL871005   EL871782   EL871783   EL885265   EL886763   ES689184   ES695971   ES695978   ES696611   ES697259   EV575469   EV576858   EV576863   EV576988   EV577376   EV577930   EV578373   EV579084   EV579612   EV580830   EV581555   EV583608   EV588765   EV594568   EV595615   EV599269   EV600656   GH942736   GH945021   GH948656   GH951558   GH958799   GH974427   GH978061   GH978222   GH980617   GH984710   M11254 AAA28560
UniProtKB/Swiss-Prot	P07486
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences	EPD - Eukarytoic Promoter Database, an annotated collection of POL II promoters • 23031
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   pole cell   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) pole cell   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) germline cell   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) germline cell   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   crystal cell   (Fisher et al., 2012) dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic head sensory system   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) germline cell   (Fisher et al., 2012) gonad   (Fisher et al., 2012) ventral sensory complex primordium   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference adult stage     (Tso et al., 1985)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference adult stage   flight muscle   • myofibril | restricted (Sullivan et al., 2003) flight muscle   • sarcomere | restricted (Sullivan et al., 2003) flight muscle   • M band (Sullivan et al., 2003) flight muscle   • Z disc (Sullivan et al., 2003) mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
	Glycolytic enzymes, including Gpdh protein are localized to M bands and Z discs, as visualized in the isolated myofibrils of flight muscles, where immunoreactivity appears as alternating bright and less-intense bands. (Sullivan et al., 2003)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Cermelli et al., 2006) M band inferred from direct assay (Sullivan et al., 2003) Z disc inferred from direct assay (Sullivan et al., 2003)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1928.575 Larval Midgut    1274.4 Larval Hindgut    2099.9 Larval Malpighian Tubules    2307.1 Larval Fat Body    4619.8 Larval Salivary Gland    2743.7 Larval Trachea    1928.575 Larval Carcass    4431.875 Adult Head    2264.6 Adult Eye    2282.225 Adult Brain    1692.2 Adult Thoracic-Abdominal Ganglion    2128.8 Adult Crop    3060.6 Adult Midgut    1051.1 Adult Hindgut    2996 Adult Malpighian Tubules    2193.5 Adult Fat Body    3201.4 Adult Salivary Gland    6857.8 Adult Heart    3309.3 Adult VirginFemale Spermatheca    3359 Adult InseminatedFemale Spermatheca    3158.3 Adult Ovary    1673.8 Adult Testis    189.3 Adult Male Accessory Gland    1046.5 Adult Carcass    4892.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1928.575) Larval Midgut  (1274.4) Larval Hindgut  (2099.9) Larval Malpighian Tubules  (2307.1) Larval Fat Body  (4619.8) Larval Salivary Gland  (2743.7) Larval Trachea  (1928.575) Larval Carcass  (4431.875) Adult Head  (2264.6) Adult Eye  (2282.225) Adult Brain  (1692.2) Adult Thoracic-Abdominal Ganglion  (2128.8) Adult Crop  (3060.6) Adult Midgut  (1051.1) Adult Hindgut  (2996) Adult Malpighian Tubules  (2193.5) Adult Fat Body  (3201.4) Adult Salivary Gland  (6857.8) Adult Heart  (3309.3) Adult VirginFemale Spermatheca  (3359) Adult InseminatedFemale Spermatheca  (3158.3) Adult Ovary  (1673.8) Adult Testis    189.3 Adult Male Accessory Gland  (1046.5) Adult Carcass  (4892.2) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1928.575) Larval Midgut  (1274.4) Larval Hindgut  (2099.9) Larval Malpighian Tubules  (2307.1) Larval Fat Body  (4619.8) Larval Salivary Gland  (2743.7) Larval Trachea  (1928.575) Larval Carcass  (4431.875) Adult Head  (2264.6) Adult Eye  (2282.225) Adult Brain  (1692.2) Adult Thoracic-Abdominal Ganglion  (2128.8) Adult Crop  (3060.6) Adult Midgut  1051.1 Adult Hindgut  (2996) Adult Malpighian Tubules  (2193.5) Adult Fat Body  (3201.4) Adult Salivary Gland  (6857.8) Adult Heart  (3309.3) Adult VirginFemale Spermatheca  (3359) Adult InseminatedFemale Spermatheca  (3158.3) Adult Ovary  (1673.8) Adult Testis    189.3 Adult Male Accessory Gland  1046.5 Adult Carcass  (4892.2) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1928.575 Larval Midgut    1274.4 Larval Hindgut    2099.9 Larval Malpighian Tubules    2307.1 Larval Fat Body    4619.8 Larval Salivary Gland    2743.7 Larval Trachea    1928.575 Larval Carcass    4431.875 Adult Head    2264.6 Adult Eye    2282.225 Adult Brain    1692.2 Adult Thoracic-Abdominal Ganglion    2128.8 Adult Crop    3060.6 Adult Midgut    1051.1 Adult Hindgut    2996 Adult Malpighian Tubules    2193.5 Adult Fat Body    3201.4 Adult Salivary Gland    6857.8 Adult Heart    3309.3 Adult VirginFemale Spermatheca    3359 Adult InseminatedFemale Spermatheca    3158.3 Adult Ovary    1673.8 Adult Testis    189.3 Adult Male Accessory Gland    1046.5 Adult Carcass    4892.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1928.575 Larval Midgut    1274.4 Larval Hindgut    2099.9 Larval Malpighian Tubules    2307.1 Larval Fat Body    4619.8 Larval Salivary Gland    2743.7 Larval Trachea    1928.575 Larval Carcass    4431.875 Adult Head    2264.6 Adult Eye    2282.225 Adult Brain    1692.2 Adult Thoracic-Abdominal Ganglion    2128.8 Adult Crop    3060.6 Adult Midgut    1051.1 Adult Hindgut    2996 Adult Malpighian Tubules    2193.5 Adult Fat Body    3201.4 Adult Salivary Gland    6857.8 Adult Heart    3309.3 Adult VirginFemale Spermatheca    3359 Adult InseminatedFemale Spermatheca    3158.3 Adult Ovary    1673.8 Adult Testis    189.3 Adult Male Accessory Gland    1046.5 Adult Carcass    4892.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1928.575) Larval Midgut  (1274.4) Larval Hindgut  (2099.9) Larval Malpighian Tubules  (2307.1) Larval Fat Body  (4619.8) Larval Salivary Gland  (2743.7) Larval Trachea  (1928.575) Larval Carcass  (4431.875) Adult Head  (2264.6) Adult Eye  (2282.225) Adult Brain  (1692.2) Adult Thoracic-Abdominal Ganglion  (2128.8) Adult Crop  (3060.6) Adult Midgut  (1051.1) Adult Hindgut  (2996) Adult Malpighian Tubules  (2193.5) Adult Fat Body  (3201.4) Adult Salivary Gland  (6857.8) Adult Heart  (3309.3) Adult VirginFemale Spermatheca  (3359) Adult InseminatedFemale Spermatheca  (3158.3) Adult Ovary  (1673.8) Adult Testis    189.3 Adult Male Accessory Gland  (1046.5) Adult Carcass  (4892.2) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1928.575) Larval Midgut  1274.4 Larval Hindgut  (2099.9) Larval Malpighian Tubules  (2307.1) Larval Fat Body  (4619.8) Larval Salivary Gland  (2743.7) Larval Trachea  (1928.575) Larval Carcass  (4431.875) Adult Head  (2264.6) Adult Eye  (2282.225) Adult Brain  1692.2 Adult Thoracic-Abdominal Ganglion  (2128.8) Adult Crop  (3060.6) Adult Midgut  1051.1 Adult Hindgut  (2996) Adult Malpighian Tubules  (2193.5) Adult Fat Body  (3201.4) Adult Salivary Gland  (6857.8) Adult Heart  (3309.3) Adult VirginFemale Spermatheca  (3359) Adult InseminatedFemale Spermatheca  (3158.3) Adult Ovary  1673.8 Adult Testis    189.3 Adult Male Accessory Gland  1046.5 Adult Carcass  (4892.2) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1928.575 Larval Midgut    1274.4 Larval Hindgut    2099.9 Larval Malpighian Tubules    2307.1 Larval Fat Body    4619.8 Larval Salivary Gland    2743.7 Larval Trachea    1928.575 Larval Carcass    4431.875 Adult Head    2264.6 Adult Eye    2282.225 Adult Brain    1692.2 Adult Thoracic-Abdominal Ganglion    2128.8 Adult Crop    3060.6 Adult Midgut    1051.1 Adult Hindgut    2996 Adult Malpighian Tubules    2193.5 Adult Fat Body    3201.4 Adult Salivary Gland    6857.8 Adult Heart    3309.3 Adult VirginFemale Spermatheca    3359 Adult InseminatedFemale Spermatheca    3158.3 Adult Ovary    1673.8 Adult Testis    189.3 Adult Male Accessory Gland    1046.5 Adult Carcass    4892.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2264.6   NA  Eye    2282.225   NA  Brain    1692.2   1928.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2128.8   NA  Crop    3060.6   1274.4  Midgut    1051.1   2099.9  Hindgut    2996   2307.1  Malpighian Tubules    2193.5   4619.8  Fat Body    3201.4   2743.7  Salivary Gland    6857.8   NA  Heart    3309.3   1928.575  Trachea    NA   NA  VirginFemale Spermatheca    3359   NA  InseminatedFemale Spermatheca    3158.3   NA  Ovary    1673.8   NA  Testis    189.3   NA  Male Accessory Gland    1046.5   4431.875  Carcass    4892.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    111 central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female    520 head, virgin 4-day female    249 head, virgin 20-day female    220 head, mated 1-day female    383 head, mated 4-day female    174 head, mated 20-day female    189 head, mated 1-day male    591 head, mated 4-day male    268 head, mated 20-day male    265 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult    233 digestive system, 4-day adult    122 digestive system, 20-day adult    141 fat body, larvae L3 wandering    407 fat body, white prepupae    187 fat body, pupae P8    104 carcass, larvae L3 wandering    235 carcass, 1-day adult    1717 carcass, 4-day adult    614 carcass, 20-day adult    235 ovary, virgin 4-day female    235 ovary, mated 4-day female    204 testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (111) central nervous system, larvae L3  (97) central nervous system, pupae P8  (64) head, virgin 1-day female  (520) head, virgin 4-day female  (249) head, virgin 20-day female  (220) head, mated 1-day female  (383) head, mated 4-day female  (174) head, mated 20-day female  (189) head, mated 1-day male  (591) head, mated 4-day male  (268) head, mated 20-day male  (265) salivary gland, larvae L3 wandering  (31) salivary gland, white prepupae  (47) digestive system, larvae L3 wandering  (73) digestive system, 1-day adult  (233) digestive system, 4-day adult  (122) digestive system, 20-day adult  (141) fat body, larvae L3 wandering  (407) fat body, white prepupae  (187) fat body, pupae P8  (104) carcass, larvae L3 wandering  (235) carcass, 1-day adult  (1717) carcass, 4-day adult  (614) carcass, 20-day adult  (235) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (204) testis, mated 4-day male  (55) accessory gland, mated 4-day male  (91) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (111) central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female  (520) head, virgin 4-day female  (249) head, virgin 20-day female  (220) head, mated 1-day female  (383) head, mated 4-day female  (174) head, mated 20-day female  (189) head, mated 1-day male  (591) head, mated 4-day male  (268) head, mated 20-day male  (265) salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult  (233) digestive system, 4-day adult  (122) digestive system, 20-day adult  (141) fat body, larvae L3 wandering  (407) fat body, white prepupae  (187) fat body, pupae P8  104 carcass, larvae L3 wandering  (235) carcass, 1-day adult  (1717) carcass, 4-day adult  (614) carcass, 20-day adult  (235) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (204) testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    111 central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female    520 head, virgin 4-day female    249 head, virgin 20-day female    220 head, mated 1-day female    383 head, mated 4-day female    174 head, mated 20-day female    189 head, mated 1-day male    591 head, mated 4-day male    268 head, mated 20-day male    265 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult    233 digestive system, 4-day adult    122 digestive system, 20-day adult    141 fat body, larvae L3 wandering    407 fat body, white prepupae    187 fat body, pupae P8    104 carcass, larvae L3 wandering    235 carcass, 1-day adult    1717 carcass, 4-day adult    614 carcass, 20-day adult    235 ovary, virgin 4-day female    235 ovary, mated 4-day female    204 testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    111 central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female    520 head, virgin 4-day female    249 head, virgin 20-day female    220 head, mated 1-day female    383 head, mated 4-day female    174 head, mated 20-day female    189 head, mated 1-day male    591 head, mated 4-day male    268 head, mated 20-day male    265 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult    233 digestive system, 4-day adult    122 digestive system, 20-day adult    141 fat body, larvae L3 wandering    407 fat body, white prepupae    187 fat body, pupae P8    104 carcass, larvae L3 wandering    235 carcass, 1-day adult    1717 carcass, 4-day adult    614 carcass, 20-day adult    235 ovary, virgin 4-day female    235 ovary, mated 4-day female    204 testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (111) central nervous system, larvae L3  (97) central nervous system, pupae P8  (64) head, virgin 1-day female  (520) head, virgin 4-day female  (249) head, virgin 20-day female  (220) head, mated 1-day female  (383) head, mated 4-day female  (174) head, mated 20-day female  (189) head, mated 1-day male  (591) head, mated 4-day male  (268) head, mated 20-day male  (265) salivary gland, larvae L3 wandering  31 salivary gland, white prepupae  (47) digestive system, larvae L3 wandering  (73) digestive system, 1-day adult  (233) digestive system, 4-day adult  (122) digestive system, 20-day adult  (141) fat body, larvae L3 wandering  (407) fat body, white prepupae  (187) fat body, pupae P8  (104) carcass, larvae L3 wandering  (235) carcass, 1-day adult  (1717) carcass, 4-day adult  (614) carcass, 20-day adult  (235) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (204) testis, mated 4-day male  (55) accessory gland, mated 4-day male  (91) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  111 central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female  (520) head, virgin 4-day female  (249) head, virgin 20-day female  (220) head, mated 1-day female  (383) head, mated 4-day female  (174) head, mated 20-day female  (189) head, mated 1-day male  (591) head, mated 4-day male  (268) head, mated 20-day male  (265) salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult  (233) digestive system, 4-day adult  122 digestive system, 20-day adult  141 fat body, larvae L3 wandering  (407) fat body, white prepupae  (187) fat body, pupae P8  104 carcass, larvae L3 wandering  (235) carcass, 1-day adult  (1717) carcass, 4-day adult  (614) carcass, 20-day adult  (235) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (204) testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    111 central nervous system, larvae L3    97 central nervous system, pupae P8    64 head, virgin 1-day female    520 head, virgin 4-day female    249 head, virgin 20-day female    220 head, mated 1-day female    383 head, mated 4-day female    174 head, mated 20-day female    189 head, mated 1-day male    591 head, mated 4-day male    268 head, mated 20-day male    265 salivary gland, larvae L3 wandering    31 salivary gland, white prepupae    47 digestive system, larvae L3 wandering    73 digestive system, 1-day adult    233 digestive system, 4-day adult    122 digestive system, 20-day adult    141 fat body, larvae L3 wandering    407 fat body, white prepupae    187 fat body, pupae P8    104 carcass, larvae L3 wandering    235 carcass, 1-day adult    1717 carcass, 4-day adult    614 carcass, 20-day adult    235 ovary, virgin 4-day female    235 ovary, mated 4-day female    204 testis, mated 4-day male    55 accessory gland, mated 4-day male    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression. Peak expression observed at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    465 embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr    190 embryo 16-18hr    257 embryo 18-20hr    353 embryo 20-22hr    425 embryo 22-24hr    378 larva L1    1130 larva L2    1359 larva L3 12hr old    1666 larva L3 puffstage 1-2    1459 larva L3 puffstage 3-6    861 larva L3 puffstage 7-9    376 white prepupae new    246 white prepupae 12hr    159 white prepupae 24hr    146 pupae 2d postWPP    388 pupae 3d postWPP    1144 pupae 4d postWPP    2375 adult male 01day    2138 adult male 05day    1690 adult male 30day    410 adult female 01day    2057 adult female 05day    668 adult female 30day    477 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (465) embryo 02-04hr  (65) embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr  (29) embryo 14-16hr  (190) embryo 16-18hr  (257) embryo 18-20hr  (353) embryo 20-22hr  (425) embryo 22-24hr  (378) larva L1  (1130) larva L2  (1359) larva L3 12hr old  (1666) larva L3 puffstage 1-2  (1459) larva L3 puffstage 3-6  (861) larva L3 puffstage 7-9  (376) white prepupae new  (246) white prepupae 12hr  (159) white prepupae 24hr  (146) pupae 2d postWPP  (388) pupae 3d postWPP  (1144) pupae 4d postWPP  (2375) adult male 01day  (2138) adult male 05day  (1690) adult male 30day  (410) adult female 01day  (2057) adult female 05day  (668) adult female 30day  (477) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (465) embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr  (190) embryo 16-18hr  (257) embryo 18-20hr  (353) embryo 20-22hr  (425) embryo 22-24hr  (378) larva L1  (1130) larva L2  (1359) larva L3 12hr old  (1666) larva L3 puffstage 1-2  (1459) larva L3 puffstage 3-6  (861) larva L3 puffstage 7-9  (376) white prepupae new  (246) white prepupae 12hr  (159) white prepupae 24hr  (146) pupae 2d postWPP  (388) pupae 3d postWPP  (1144) pupae 4d postWPP  (2375) adult male 01day  (2138) adult male 05day  (1690) adult male 30day  (410) adult female 01day  (2057) adult female 05day  (668) adult female 30day  (477) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    465 embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr    190 embryo 16-18hr    257 embryo 18-20hr    353 embryo 20-22hr    425 embryo 22-24hr    378 larva L1    1130 larva L2    1359 larva L3 12hr old    1666 larva L3 puffstage 1-2    1459 larva L3 puffstage 3-6    861 larva L3 puffstage 7-9    376 white prepupae new    246 white prepupae 12hr    159 white prepupae 24hr    146 pupae 2d postWPP    388 pupae 3d postWPP    1144 pupae 4d postWPP    2375 adult male 01day    2138 adult male 05day    1690 adult male 30day    410 adult female 01day    2057 adult female 05day    668 adult female 30day    477 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    465 embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr    190 embryo 16-18hr    257 embryo 18-20hr    353 embryo 20-22hr    425 embryo 22-24hr    378 larva L1    1130 larva L2    1359 larva L3 12hr old    1666 larva L3 puffstage 1-2    1459 larva L3 puffstage 3-6    861 larva L3 puffstage 7-9    376 white prepupae new    246 white prepupae 12hr    159 white prepupae 24hr    146 pupae 2d postWPP    388 pupae 3d postWPP    1144 pupae 4d postWPP    2375 adult male 01day    2138 adult male 05day    1690 adult male 30day    410 adult female 01day    2057 adult female 05day    668 adult female 30day    477 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (465) embryo 02-04hr  (65) embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr  29 embryo 14-16hr  (190) embryo 16-18hr  (257) embryo 18-20hr  (353) embryo 20-22hr  (425) embryo 22-24hr  (378) larva L1  (1130) larva L2  (1359) larva L3 12hr old  (1666) larva L3 puffstage 1-2  (1459) larva L3 puffstage 3-6  (861) larva L3 puffstage 7-9  (376) white prepupae new  (246) white prepupae 12hr  (159) white prepupae 24hr  (146) pupae 2d postWPP  (388) pupae 3d postWPP  (1144) pupae 4d postWPP  (2375) adult male 01day  (2138) adult male 05day  (1690) adult male 30day  (410) adult female 01day  (2057) adult female 05day  (668) adult female 30day  (477) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (465) embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr  (190) embryo 16-18hr  (257) embryo 18-20hr  (353) embryo 20-22hr  (425) embryo 22-24hr  (378) larva L1  (1130) larva L2  (1359) larva L3 12hr old  (1666) larva L3 puffstage 1-2  (1459) larva L3 puffstage 3-6  (861) larva L3 puffstage 7-9  (376) white prepupae new  (246) white prepupae 12hr  (159) white prepupae 24hr  (146) pupae 2d postWPP  (388) pupae 3d postWPP  (1144) pupae 4d postWPP  (2375) adult male 01day  (2138) adult male 05day  (1690) adult male 30day  (410) adult female 01day  (2057) adult female 05day  (668) adult female 30day  (477) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    465 embryo 02-04hr    65 embryo 04-06hr    11 embryo 06-08hr    7 embryo 08-10hr    11 embryo 10-12hr    20 embryo 12-14hr    29 embryo 14-16hr    190 embryo 16-18hr    257 embryo 18-20hr    353 embryo 20-22hr    425 embryo 22-24hr    378 larva L1    1130 larva L2    1359 larva L3 12hr old    1666 larva L3 puffstage 1-2    1459 larva L3 puffstage 3-6    861 larva L3 puffstage 7-9    376 white prepupae new    246 white prepupae 12hr    159 white prepupae 24hr    146 pupae 2d postWPP    388 pupae 3d postWPP    1144 pupae 4d postWPP    2375 adult male 01day    2138 adult male 05day    1690 adult male 30day    410 adult female 01day    2057 adult female 05day    668 adult female 30day    477 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    296 Schneider line 2 Sg4    151 embryonic 1182-4H    141 embryonic GM2    101 embryonic Kc167    138 embryonic S1    121 embryonic S3    124 leg disc CME L1    146 wing disc CME-W2    160 wing disc ML-DmD8    196 wing disc ML-DmD9    218 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    163 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    160 eye-antennal disc ML-DmD11    139 antennal disc ML-DmD20-c5    191 mixed discs ML-DmD4-c1    281 CNS ML-DmBG1-c1    209 CNS ML-DmBG2-c2    134 tumorous blood cells mbn2    132 ovary fGS/OSS    156 ovary OSC    72 ovary OSS    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (296) Schneider line 2 Sg4  (151) embryonic 1182-4H  (141) embryonic GM2  (101) embryonic Kc167  (138) embryonic S1  (121) embryonic S3  (124) leg disc CME L1  (146) wing disc CME-W2  (160) wing disc ML-DmD8  (196) wing disc ML-DmD9  (218) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (163) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (160) eye-antennal disc ML-DmD11  (139) antennal disc ML-DmD20-c5  (191) mixed discs ML-DmD4-c1  (281) CNS ML-DmBG1-c1  (209) CNS ML-DmBG2-c2  (134) tumorous blood cells mbn2  (132) ovary fGS/OSS  (156) ovary OSC  (72) ovary OSS  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (296) Schneider line 2 Sg4  (151) embryonic 1182-4H  (141) embryonic GM2  101 embryonic Kc167  (138) embryonic S1  (121) embryonic S3  (124) leg disc CME L1  (146) wing disc CME-W2  (160) wing disc ML-DmD8  (196) wing disc ML-DmD9  (218) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (163) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (160) eye-antennal disc ML-DmD11  (139) antennal disc ML-DmD20-c5  (191) mixed discs ML-DmD4-c1  (281) CNS ML-DmBG1-c1  (209) CNS ML-DmBG2-c2  (134) tumorous blood cells mbn2  (132) ovary fGS/OSS  (156) ovary OSC    72 ovary OSS    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    296 Schneider line 2 Sg4    151 embryonic 1182-4H    141 embryonic GM2    101 embryonic Kc167    138 embryonic S1    121 embryonic S3    124 leg disc CME L1    146 wing disc CME-W2    160 wing disc ML-DmD8    196 wing disc ML-DmD9    218 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    163 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    160 eye-antennal disc ML-DmD11    139 antennal disc ML-DmD20-c5    191 mixed discs ML-DmD4-c1    281 CNS ML-DmBG1-c1    209 CNS ML-DmBG2-c2    134 tumorous blood cells mbn2    132 ovary fGS/OSS    156 ovary OSC    72 ovary OSS    39 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    296 Schneider line 2 Sg4    151 embryonic 1182-4H    141 embryonic GM2    101 embryonic Kc167    138 embryonic S1    121 embryonic S3    124 leg disc CME L1    146 wing disc CME-W2    160 wing disc ML-DmD8    196 wing disc ML-DmD9    218 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    163 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    160 eye-antennal disc ML-DmD11    139 antennal disc ML-DmD20-c5    191 mixed discs ML-DmD4-c1    281 CNS ML-DmBG1-c1    209 CNS ML-DmBG2-c2    134 tumorous blood cells mbn2    132 ovary fGS/OSS    156 ovary OSC    72 ovary OSS    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (296) Schneider line 2 Sg4  (151) embryonic 1182-4H  (141) embryonic GM2  (101) embryonic Kc167  (138) embryonic S1  (121) embryonic S3  (124) leg disc CME L1  (146) wing disc CME-W2  (160) wing disc ML-DmD8  (196) wing disc ML-DmD9  (218) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (163) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (160) eye-antennal disc ML-DmD11  (139) antennal disc ML-DmD20-c5  (191) mixed discs ML-DmD4-c1  (281) CNS ML-DmBG1-c1  (209) CNS ML-DmBG2-c2  (134) tumorous blood cells mbn2  (132) ovary fGS/OSS  (156) ovary OSC  (72) ovary OSS  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (296) Schneider line 2 Sg4  (151) embryonic 1182-4H  141 embryonic GM2  101 embryonic Kc167  138 embryonic S1  121 embryonic S3  124 leg disc CME L1  (146) wing disc CME-W2  (160) wing disc ML-DmD8  (196) wing disc ML-DmD9  (218) wing disc ML-DmD16-c3  (144) wing disc ML-DmD21  (163) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (160) eye-antennal disc ML-DmD11  139 antennal disc ML-DmD20-c5  (191) mixed discs ML-DmD4-c1  (281) CNS ML-DmBG1-c1  (209) CNS ML-DmBG2-c2  134 tumorous blood cells mbn2  132 ovary fGS/OSS  (156) ovary OSC    72 ovary OSS    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    296 Schneider line 2 Sg4    151 embryonic 1182-4H    141 embryonic GM2    101 embryonic Kc167    138 embryonic S1    121 embryonic S3    124 leg disc CME L1    146 wing disc CME-W2    160 wing disc ML-DmD8    196 wing disc ML-DmD9    218 wing disc ML-DmD16-c3    144 wing disc ML-DmD21    163 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    160 eye-antennal disc ML-DmD11    139 antennal disc ML-DmD20-c5    191 mixed discs ML-DmD4-c1    281 CNS ML-DmBG1-c1    209 CNS ML-DmBG2-c2    134 tumorous blood cells mbn2    132 ovary fGS/OSS    156 ovary OSC    72 ovary OSS    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    291 cold shock, 4-day adult    178 heat shock, 4-day adult    897 Cadmium 50 mM 6 hrs, larvae L3    1206 Cadmium 50 mM 12 hrs, larvae L3    853 Cadmium 50 mM 48 hrs, 4-day adult    792 Cadmium 100 mM 48 hrs, 4-day adult    303 Copper 0.5 mM 12 hrs, larvae L3    968 Copper 15 mM 48 hrs, 4-day adult    119 Zinc 5 mM 12 hrs, larvae L3    581 Zinc 4.5 mM 48 hrs, 4-day adult    196 Ethanol 2.5% 3 hrs, larvae L3    632 Ethanol 5% 3 hrs, larvae L3    912 Ethanol 10% 3 hrs, larvae L3    1490 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1026 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    256 Caffeine 25 mg/ml 48 hrs, 4-day adult    261 Paraquat 5 mM 48 hrs, 4-day adult    551 Paraquat 10 mM 48 hrs, 4-day adult    654 Rotenone 2 μg 12 hrs, larvae L3    1195 Rotenone 8 μg 12 hrs, larvae L3    1496 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (291) cold shock, 4-day adult  (178) heat shock, 4-day adult  (897) Cadmium 50 mM 6 hrs, larvae L3  (1206) Cadmium 50 mM 12 hrs, larvae L3  (853) Cadmium 50 mM 48 hrs, 4-day adult  (792) Cadmium 100 mM 48 hrs, 4-day adult  (303) Copper 0.5 mM 12 hrs, larvae L3  (968) Copper 15 mM 48 hrs, 4-day adult  (119) Zinc 5 mM 12 hrs, larvae L3  (581) Zinc 4.5 mM 48 hrs, 4-day adult  (196) Ethanol 2.5% 3 hrs, larvae L3  (632) Ethanol 5% 3 hrs, larvae L3  (912) Ethanol 10% 3 hrs, larvae L3  (1490) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1026) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (256) Caffeine 25 mg/ml 48 hrs, 4-day adult  (261) Paraquat 5 mM 48 hrs, 4-day adult  (551) Paraquat 10 mM 48 hrs, 4-day adult  (654) Rotenone 2 μg 12 hrs, larvae L3  (1195) Rotenone 8 μg 12 hrs, larvae L3  (1496) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (291) cold shock, 4-day adult  (178) heat shock, 4-day adult  (897) Cadmium 50 mM 6 hrs, larvae L3  (1206) Cadmium 50 mM 12 hrs, larvae L3  (853) Cadmium 50 mM 48 hrs, 4-day adult  (792) Cadmium 100 mM 48 hrs, 4-day adult  (303) Copper 0.5 mM 12 hrs, larvae L3  (968) Copper 15 mM 48 hrs, 4-day adult  (119) Zinc 5 mM 12 hrs, larvae L3  (581) Zinc 4.5 mM 48 hrs, 4-day adult  (196) Ethanol 2.5% 3 hrs, larvae L3  (632) Ethanol 5% 3 hrs, larvae L3  (912) Ethanol 10% 3 hrs, larvae L3  (1490) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1026) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (256) Caffeine 25 mg/ml 48 hrs, 4-day adult  (261) Paraquat 5 mM 48 hrs, 4-day adult  (551) Paraquat 10 mM 48 hrs, 4-day adult  (654) Rotenone 2 μg 12 hrs, larvae L3  (1195) Rotenone 8 μg 12 hrs, larvae L3  (1496) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    291 cold shock, 4-day adult    178 heat shock, 4-day adult    897 Cadmium 50 mM 6 hrs, larvae L3    1206 Cadmium 50 mM 12 hrs, larvae L3    853 Cadmium 50 mM 48 hrs, 4-day adult    792 Cadmium 100 mM 48 hrs, 4-day adult    303 Copper 0.5 mM 12 hrs, larvae L3    968 Copper 15 mM 48 hrs, 4-day adult    119 Zinc 5 mM 12 hrs, larvae L3    581 Zinc 4.5 mM 48 hrs, 4-day adult    196 Ethanol 2.5% 3 hrs, larvae L3    632 Ethanol 5% 3 hrs, larvae L3    912 Ethanol 10% 3 hrs, larvae L3    1490 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1026 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    256 Caffeine 25 mg/ml 48 hrs, 4-day adult    261 Paraquat 5 mM 48 hrs, 4-day adult    551 Paraquat 10 mM 48 hrs, 4-day adult    654 Rotenone 2 μg 12 hrs, larvae L3    1195 Rotenone 8 μg 12 hrs, larvae L3    1496 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    291 cold shock, 4-day adult    178 heat shock, 4-day adult    897 Cadmium 50 mM 6 hrs, larvae L3    1206 Cadmium 50 mM 12 hrs, larvae L3    853 Cadmium 50 mM 48 hrs, 4-day adult    792 Cadmium 100 mM 48 hrs, 4-day adult    303 Copper 0.5 mM 12 hrs, larvae L3    968 Copper 15 mM 48 hrs, 4-day adult    119 Zinc 5 mM 12 hrs, larvae L3    581 Zinc 4.5 mM 48 hrs, 4-day adult    196 Ethanol 2.5% 3 hrs, larvae L3    632 Ethanol 5% 3 hrs, larvae L3    912 Ethanol 10% 3 hrs, larvae L3    1490 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1026 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    256 Caffeine 25 mg/ml 48 hrs, 4-day adult    261 Paraquat 5 mM 48 hrs, 4-day adult    551 Paraquat 10 mM 48 hrs, 4-day adult    654 Rotenone 2 μg 12 hrs, larvae L3    1195 Rotenone 8 μg 12 hrs, larvae L3    1496 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (291) cold shock, 4-day adult  (178) heat shock, 4-day adult  (897) Cadmium 50 mM 6 hrs, larvae L3  (1206) Cadmium 50 mM 12 hrs, larvae L3  (853) Cadmium 50 mM 48 hrs, 4-day adult  (792) Cadmium 100 mM 48 hrs, 4-day adult  (303) Copper 0.5 mM 12 hrs, larvae L3  (968) Copper 15 mM 48 hrs, 4-day adult  (119) Zinc 5 mM 12 hrs, larvae L3  (581) Zinc 4.5 mM 48 hrs, 4-day adult  (196) Ethanol 2.5% 3 hrs, larvae L3  (632) Ethanol 5% 3 hrs, larvae L3  (912) Ethanol 10% 3 hrs, larvae L3  (1490) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1026) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (256) Caffeine 25 mg/ml 48 hrs, 4-day adult  (261) Paraquat 5 mM 48 hrs, 4-day adult  (551) Paraquat 10 mM 48 hrs, 4-day adult  (654) Rotenone 2 μg 12 hrs, larvae L3  (1195) Rotenone 8 μg 12 hrs, larvae L3  (1496) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (291) cold shock, 4-day adult  (178) heat shock, 4-day adult  (897) Cadmium 50 mM 6 hrs, larvae L3  (1206) Cadmium 50 mM 12 hrs, larvae L3  (853) Cadmium 50 mM 48 hrs, 4-day adult  (792) Cadmium 100 mM 48 hrs, 4-day adult  (303) Copper 0.5 mM 12 hrs, larvae L3  (968) Copper 15 mM 48 hrs, 4-day adult  119 Zinc 5 mM 12 hrs, larvae L3  (581) Zinc 4.5 mM 48 hrs, 4-day adult  (196) Ethanol 2.5% 3 hrs, larvae L3  (632) Ethanol 5% 3 hrs, larvae L3  (912) Ethanol 10% 3 hrs, larvae L3  (1490) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1026) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (256) Caffeine 25 mg/ml 48 hrs, 4-day adult  (261) Paraquat 5 mM 48 hrs, 4-day adult  (551) Paraquat 10 mM 48 hrs, 4-day adult  (654) Rotenone 2 μg 12 hrs, larvae L3  (1195) Rotenone 8 μg 12 hrs, larvae L3  (1496) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    291 cold shock, 4-day adult    178 heat shock, 4-day adult    897 Cadmium 50 mM 6 hrs, larvae L3    1206 Cadmium 50 mM 12 hrs, larvae L3    853 Cadmium 50 mM 48 hrs, 4-day adult    792 Cadmium 100 mM 48 hrs, 4-day adult    303 Copper 0.5 mM 12 hrs, larvae L3    968 Copper 15 mM 48 hrs, 4-day adult    119 Zinc 5 mM 12 hrs, larvae L3    581 Zinc 4.5 mM 48 hrs, 4-day adult    196 Ethanol 2.5% 3 hrs, larvae L3    632 Ethanol 5% 3 hrs, larvae L3    912 Ethanol 10% 3 hrs, larvae L3    1490 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1026 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    256 Caffeine 25 mg/ml 48 hrs, 4-day adult    261 Paraquat 5 mM 48 hrs, 4-day adult    551 Paraquat 10 mM 48 hrs, 4-day adult    654 Rotenone 2 μg 12 hrs, larvae L3    1195 Rotenone 8 μg 12 hrs, larvae L3    1496 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_10 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD24323 RE69448 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001091 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12055-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Gapdh1 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Gapdh1GD7467 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Gapdh1 Class Mutagen Stocks Known lesion Gapdh1G2285 P-element activity 1 -- Gapdh1825T natural population 0 -- Gapdh1850T natural population 0 --
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Gapdh1 Class Mutagen Stocks Known lesion Gapdh1GD7467 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Gapdh1GL01094 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gapdh1KK108377 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gapdh1-3.0 in vitro construct 0 Yes Gapdh1-4.7 in vitro construct 0 Yes Gapdh1-8.5 in vitro construct 0 Yes Gapdh1Gapdh2.cSa in vitro construct - regulatory fusion 0 Yes Gapdh1GD17322 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)CA53 (Warren et al., 1996) Df(2R)cn79b9 (Warren et al., 1996) Df(2R)cn84h (Warren et al., 1996) Df(2R)cn-h3 (Warren et al., 1996) Df(2R)Exel6054 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7467} NA P{GD17322} NA P{KK108377} NA P{TRiP.GL01094} NA characterization construct P{GAP1-3.0} NA P{GAP1-4.7} NA P{GAP1-8.5} NA P{GAP2/1} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}l(2)SH1667SH1667 No insertion of mobile activating element P{EP}Gapdh1G2285 NA
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity inferred from direct assay (Sun et al., 1988)
Biological Process
CV term Evidence References
glycolysis inferred from expression pattern (Sun et al., 1988)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Cermelli et al., 2006) M band inferred from direct assay (Sullivan et al., 2003) Z disc inferred from direct assay (Sullivan et al., 2003)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity inferred from sequence or structural similarity with UniProtKB:P17244 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1988.4.1) NAD binding inferred from electronic annotation with InterPro:IPR006424 (FlyBase Curators et al., 2004-) NADP binding inferred from electronic annotation with InterPro:IPR006424 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
glycolysis non-traceable author statement (Swiss-Prot Project Members, 1988.4.1) oxidation-reduction process inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
cytoplasm non-traceable author statement (Swiss-Prot Project Members, 1988.4.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Gapdh1 - AnxB10 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - CG10638 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - CG10887 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - CG8353 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - Gapdh2 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - Hsc70-2 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - Mdh2 experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - RpS15Ab experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - bs experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - regucalcin experimental knowledge based (Guruharsha et al., 2011) Gapdh1 - βTub85D experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Gapdh1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61596 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001091 DroID - A comprehensive database of gene and protein interactions. • FBgn0001091 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35728
Orthologs
OrthoDB Orthologs (149) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GJ086 Dipteran inclusive ortholog search EOG67SSPK Insect inclusive ortholog search EOG670SD2 Arthropod inclusive ortholog search EOG66M91C Metazoa inclusive ortholog search EOG6BGNPV
Orthologs in Drosophila Species (EOG6GJ086)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Gapdh1     Drosophila melanogaster fruit fly  Dmel\Gapdh2     Drosophila sechellia   Dsec\GM20756   Y Drosophila sechellia   Dsec\GM22592   Y Drosophila erecta   Dere\GG10711 Y Y Drosophila erecta   Dere\GG17924   Y Drosophila yakuba   Dyak\Gapdh1 Y Y Drosophila yakuba   Dyak\GE17231   Y Drosophila ananassae   Dana\GF17051   Y Drosophila pseudoobscura pseudoobscura   Dpse\Gapdh2   Y Drosophila persimilis   Dper\GL10260   Y Drosophila willistoni   Dwil\GK17768   Y Drosophila virilis   Dvir\GJ20492   Y Drosophila mojavensis   Dmoj\GI20756   Y Drosophila grimshawi   Dgri\GH21340   Y
Orthologs in non-Drosophila Dipterans (EOG67SSPK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL016984 Y Anopheles gambiae Malaria mosquito  Agam\AGAP009623 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005597 Y
Orthologs in non-Dipteran Insects (EOG670SD2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Gapdh Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007624 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16788 Y Atta cephalotes Leafcutter ant  Acep\ACEP17085 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO18811 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18465 Y Linepithema humile Argentine ant  Lhum\LH21746 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB21096 Y Solenopsis invicta Red fire ant  Sinv\SINV11437 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI002318 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008700 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009769 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009148 Y Bombyx mori Silkmoth  Bmor\BmGAPDH Y Pediculus humanus Human body louse  Phum\PHUM128020 Y Tribolium castaneum Red flour beetle  Tcas\TC006170 Y
Orthologs in non-Insect Arthropods (EOG66M91C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Olr1766 Y Ixodes scapularis Deer tick  Isca\ISCW018700 Y
Orthologs in non-Arthropod Metazoa (EOG6BGNPV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\gpd-2 Y Caenorhabditis elegans Nematode  Cele\gpd-4 Y Caenorhabditis elegans Nematode  Cele\gpd-1 Y Caenorhabditis elegans Nematode  Cele\gpd-3 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007155gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027041gn Y Danio rerio Zebrafish  Drer\gapdh Y Danio rerio Zebrafish  Drer\gapdhs Y Xenopus tropicalis Western clawed frog  Xtro\gapdh Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000008782 Y Gallus gallus Domestic chicken  Ggal\GAPDH Y Mus musculus House mouse  Mmus\Gm7293 Y Mus musculus House mouse  Mmus\Gm3200 Y Mus musculus House mouse  Mmus\Gm3839 Y Mus musculus House mouse  Mmus\Gapdhs Y Mus musculus House mouse  Mmus\Gm10291 Y Mus musculus House mouse  Mmus\Gm7251 Y Mus musculus House mouse  Mmus\Gm5069 Y Mus musculus House mouse  Mmus\Gm10481 Y Mus musculus House mouse  Mmus\Gm6981 Y Mus musculus House mouse  Mmus\Gm3222 Y Mus musculus House mouse  Mmus\Gapdh Y Mus musculus House mouse  Mmus\Gm10290 Y Mus musculus House mouse  Mmus\Gm10293 Y Mus musculus House mouse  Mmus\Gm6669 Y Mus musculus House mouse  Mmus\Gm10313 Y Mus musculus House mouse  Mmus\Gm10566 Y Mus musculus House mouse  Mmus\Gm5507 Y Mus musculus House mouse  Mmus\Gm4795 Y Mus musculus House mouse  Mmus\Gm8055 Y Mus musculus House mouse  Mmus\Gm9034 Y Mus musculus House mouse  Mmus\ENSMUSG00000059468 Y Mus musculus House mouse  Mmus\Gm10327 Y Mus musculus House mouse  Mmus\Gm6316 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033388 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000036820 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029111 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024418 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000017139 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000027574 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023547 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000032611 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033797 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038964 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031758 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000016400 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029635 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000034205 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000015856 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038181 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024217 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000009394 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000026809 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000032435 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024500 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033702 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000032205 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000009844 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030429 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033506 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042521 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042057 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000022425 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000032069 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030056 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000027471 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000032754 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000017388 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024486 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042908 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000025316 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000027866 Y Rattus norvegicus Norway rat  Rnor\Gapdhs Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042034 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000021319 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000025756 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000008363 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033732 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000043395 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023260 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031519 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042481 Y Rattus norvegicus Norway rat  Rnor\Gapdh-ps2 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000010043 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000026991 Y Rattus norvegicus Norway rat  Rnor\RGD1564688 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000019726 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023365 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000043263 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000034144 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031542 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030638 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023960 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000037802 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024166 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033635 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000021858 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000022174 Y Rattus norvegicus Norway rat  Rnor\Gapdh Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031351 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000025797 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000025201 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029758 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024155 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000033401 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031761 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042314 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000002195 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031978 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029967 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042051 Y Homo sapiens Human  Hsap\GAPDH Y Homo sapiens Human  Hsap\GAPDHS Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\GAPDH     Hsap\GAPDHS
AAA Orthologs (2) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila erecta Dere\GG10711 Drosophila yakuba Dyak\Gapdh1
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	26984 y1 w*; P{EP}Gapdh1G2285 36842 y1 sc* v1; P{TRiP.GL01094}attP2
VDRC	v100596 P{KK108377}VIE-260B v31631 w1118; P{GD7467}v31631 v31632 w1118; P{GD7467}v31632
Genomic Clones ( 1 )
	BACR04B09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 309 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24323 RE69448 RH55882
Other clones	yak-em_Gapdh1
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT15832 AT30010 GH01044 GH01989 GH03381 GH05608 GH06005 GH06530 GH07229 GH07717 GH08119 GH08703 GH08926 GH09043 GH09359 GH09859 GH09889 GH10187 GH10719 GH11260 GH11424 GH11453 GH12540 GH12586 GH12949 GH13626 GH14452 GH14526 GH14771 GH14802 GH14883 GH15906 GH16332 GH16812 GH17434 GH17834 GH18058 GH18701 GH19391 GH19476 GH20323 GH21512 GH21639 GH22338 GH23301 GH23359 GH23913 GH24481 GH24760 GH25117 GH25983 GH26853 GH27501 GM01105 GM01115 GM01129 GM04007 GM04854 GM06157 GM09554 GM14108 GM22713 GM23785 GM26968 GM32587 HL08019 LD03378 LD36171 LD36512 LD38035 LD42536 LD42965 LD45425 LP01695 LP02910 LP03543 LP03708 LP06556 LP06594 LP07795 LP08555 LP10586 LP11843 LP11933 LP14173 RE13061 RE15239 RE16232 RE20377 RE25322 RE30860 RE30996 RE32726 RE37242 RE57763 RE64303 RE66192 RE66518 RE69191 RE71096 RH17313 RH38027 RH38038 RH38229 RH39046 RH39131 RH43227 RH44825 RH47476 RH49827 RH51265 RH57689 RH60805 RH61989 RH69934 SD08048 SD11748 SD13933 SD16833 SD26670 SD27029
Other clones	31013 66751 105468 277545 522874 542530 557934 569960 Dmel_dig_001739_0711_1098 Dmel_dig_004043_0707_0436 Dmel_dig_011057_0653_0682 Dmel_dig_011460_0712_0899 Dmel_dig_011699_0635_0750 Dmel_dig_014324_0675_2057 Dmel_dig_017327_0652_0648 Dmel_dig_017565_0616_1541 Dmel_dig_017690_0599_0763 Dmel_dig_018040_0677_2292 Dmel_dig_018378_0704_3060 Dmel_dig_019079_0662_3250 Dmel_neb_004500_0828_1201 Dmel_neb_011297_0641_0751 Dmel_neb_012296_0682_0665 Dmel_neb_013731_0827_3667 Dmel_neb_014392_0140_0667 EC25954 EK166446 EK230628 EK304822 EN02938 EN10813 EN12659 EN15955 GH08283 GH14256 GM06737 HL03446 HL03647 IP03145 IP03830 IP16408 IP17941 LD17056 RE02614 RE04371 RE09709 RE16282 RE16945 RE22685 RE29478 RE30630 RE30716 RE31836 RE34979 RE39427 RE39978 RE45591 RE53677 RE59628 RE59641 RE59979 RE60162 RE65240 RE67379 RE68717 RE73623 RH02121 RH02309 RH02814 RH03224 RH03969 RH04682 RH06930 RH07271 RH08474 RH09163 RH09945 RH11243 RH13990 RH15721 RH15836 RH16473 RH17824 RH17927 RH17968 RH18996 RH19123 RH22076 RH22354 RH22733 RH22866 RH22871 RH23017 RH23913 RH25173 RH26818 RH26850 RH27233 RH27340 RH27583 RH27681 RH29636 RH29663 RH29672 RH30852 RH31727 RH32117 RH32213 RH32979 RH33575 RH35681 RH35858 RH39738 RH39791 RH40019 RH40437 RH40687 RH42417 RH43435 RH44155 RH44631 RH44776 RH45248 RH45249 RH45276 RH45425 RH45908 RH46439 RH46593 RH46745 RH48253 RH49418 RH49990 RH50584 RH50758 RH51485 RH52669 RH53461 RH53976 RH55062 RH55341 RH55614 RH57627 RH60073 RH60094 RH60723 RH60744 RH62013 RH62258 RH62647 RH62863 RH63073 RH63120 RH63492 RH63914 RH64454 RH64794 RH65871 RH67425 RH68537 RH69083 RH70703 RH70724 RH71384 RH71638 RH72012 RH72496 RH72756 RH73250 RH73566 RH74457 RH74695 RP004022616 RP004156993 RP004197003 RP004229147 RP004235250 RP004238989 RP004256031 RP004262177 RP004264774 RP004363457 UT01839 UUGC0450
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0001091 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35728
Antibody Information
	polyclonal (Sullivan et al., 2003, Lee et al., 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	The Gapdh1 gene may have been derived from the Gapdh2 gene by retroposition. (Dai et al., 2006)
Other Comments
	Identified with: GH12586 <up>FlyBase curator comment: EST subsequently found to be chimeric</up>. (Zou et al., 2000) At least a substantial fraction of three glycolytic enzymes of flight muscle cells are found colocalised at the Z-discs and M-lines, glycolytic enzyme colocalisation is interdependent. Localisation of Gapdh1, Gapdh2 and Ald at the Z-discs and M-lines requires the presence of at least Gpdh at the Z-discs and M-lines. (Wojtas et al., 1997) EST GH12586 is chimeric; the 5' portion (AI134984) corresponds to part of CG4461, the 3' portion (BG632702) corresponds to part of Gapdh1. (FlyBase, 1996-) The synergistic effects of the Adh locus, or a tightly linked locus, on the quantities of the Mdh1, Gpdh, Pgm, Idh, Men and Gapdh1 gene products in D.melanogaster derived from an African population has been determined. (Li, 1992) The melanogaster and takahashi subgroups of the melanogaster group have small and large subunits of Gapdh, while another 28 species (in 15 subgroups) studied were found to have only either the large or the small subunit of Gapdh. (Wojtas et al., 1992) Gapdh1 and Gapdh2 RNA expression has been studied. (Sun et al., 1988) One of two genes (Gapdh1 and Gapdh2) that code for the enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). These genes are expressed in almost all cells, especially those that undergo a high rate of glycolysis.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080369 NM_001038847 RefSeq (Proteins) • NP_525108 NP_001033936 DDBJ / EMBL / GenBank • AA820539 AAA28560 AAF59192 AAF59192.2 AAL90381 AAO42649 ABC66066 AI455451 AY089643 BG632702 BI486075 BT004485 M11254 Entrez Gene - A searchable database of RefSeq genes. • 35728 UniProtKB/Swiss-Prot • P07486
Other Crossreferences
	EPD - Eukarytoic Promoter Database, an annotated collection of POL II promoters • 23031 InterPro domains - A database of protein families, domains, and functional sites • Glyceraldehyde-3-phosphate dehydrogenase, type I (IPR006424) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (IPR020828) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (IPR020829) Glyceraldehyde 3-phosphate dehydrogenase, active site (IPR020830) Glyceraldehyde/Erythrose phosphate dehydrogenase family (IPR020831) NAD(P)-binding domain (IPR016040) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD24323 RE69448
Linkouts
	BioGRID - A database of protein and genetic interactions • 61596 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001091 DroID - A comprehensive database of gene and protein interactions. • FBgn0001091 DRSC - Results from RNAi screens. • FBgn0001091 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001091 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12055-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0001091 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35728 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35728 modMine - Data generated by the modENCODE project. • FBgn0001091
Synonyms & Secondary IDs ( 25 )
Reported As
Symbol Synonym	BEST:GH12586   CG12055 (Pile et al., 2003, Kang et al., 2002, Mount, 2001.8.14, Cermelli et al., 2006, Dai et al., 2006, Ni et al., 2011.7.19, O'Keefe et al., 2011, Keleman et al., 2009.8.5, Cammarato et al., 2011) GA3PDH (Luque et al., 1994) GADPH (Sezgin and Eanes, 2002, Mushegian et al., 1998) gadph (Bossuyt et al., 2009) GAP (Boehm et al., 2003) Gapd (Matthews and Munstermann, 1994) Gapdh (Hoeffer et al., 2003, Warren et al., 1996, Eanes, 1994, Ahrens et al., 2007, O'Keefe et al., 2011, Lee et al., 2010, Thomas et al., 2012) GAPDH (Srere and Knull, 1998, Wojtas et al., 1997, Mendjan et al., 2006, Peralta et al., 2012, Sullivan et al., 2003, Hartig et al., 2009, van der Knaap et al., 2010, Sun et al., 2011, Chang et al., 2010, Saulière et al., 2010, Pielage et al., 2008, Duboff et al., 2012) gapdh (Hartig et al., 2009, Kind and Akhtar, 2007, Chang et al., 2010) Gapdh1 (Rehwinkel et al., 2006, Flowers et al., 2007, Li et al., 2003, Walser et al., 2006, Matta et al., 2011, Liu and Lehmann, 2008, Muse et al., 2007, Anholt and Williams, 2010, Barnes et al., 2010) GAPDH-1 (Eeken et al., 2001) gapdh-1 (Caplen et al., 2000) Gapdh-1 (Lis, 1998, Rasmussen and Lis, 1995, Sun et al., 1988) GAPDH1 (Carvalho et al., 2010) Gapdh43E   GAPDH I (de Morais Guedes et al., 2003) GAPDHI (Pinnola et al., 2007) gh12586 (Zou et al., 2000)
Name Synonym	G3-P dehydrogenase (White et al., 1999) GAPDH1 (Cho et al., 2005) glyceraldehyde-3-phosphate dehydrogenase (Boehm et al., 2003, O'Keefe et al., 2011, Sullivan et al., 2003, Sun et al., 2011) Glyceraldehyde 3 phosphate dehydrogenase (Anholt and Williams, 2010) Glyceraldehyde-3-phosphate dehydrogenase1 (Kang et al., 2002) Glyceraldehyde 3 phosphate dehydrogenase 1 (Cammarato et al., 2011) glyceraldehyde 3 phosphate dehydrogenase1 (Cermelli et al., 2006)
Secondary FlyBase IDs
	FBgn0043822
References ( 88 )
Generate a list of	All references relating to this gene ( 88 )
List References by type	Research paper  ( 58 ) Supplementary material  ( 10 ) Review  ( 4 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 ) Letter  ( 1 ) Book  ( 1 )
Recent research papers ( 8 )
	Zala et al., 2013, Cell 152(3): 479--491 Vesicular glycolysis provides on-board energy for fast axonal transport. [FBrf0220679] Duboff et al., 2012, Neuron 75(4): 618--632 Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo. [FBrf0219271] Peralta et al., 2012, J. Biol. Chem. 287(29): 24174--24185 Coiled Coil Domain-containing Protein 56 (CCDC56) Is a Novel Mitochondrial Protein Essential for Cytochrome c Oxidase Function. [FBrf0218928] Thomas et al., 2012, PLoS ONE 7(7): e40276 A Versatile Method for Cell-Specific Profiling of Translated mRNAs in Drosophila. [FBrf0218903] Vesala et al., 2012, Insect Mol. Biol. 21(1): 107--118 Cold tolerance and cold-induced modulation of gene expression in two Drosophila virilis group species with different distributions. [FBrf0217233] Matta et al., 2011, Dev. Genes Evol. 221(1): 49--57 Getting real with real-time qPCR: a case study of reference gene selection for morphological variation in Drosophila melanogaster wings. [FBrf0213646] O'Keefe et al., 2011, Hum. Mol. Genet. 20(3): 497--509 Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. [FBrf0212691] Sun et al., 2011, PLoS ONE 6(4): e18215 Systems-scale analysis reveals pathways involved in cellular response to methamphetamine. [FBrf0213560] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...