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Gene Dmel\Gβ13F

General Information
Symbol	Dmel\Gβ13F	Species	D. melanogaster
Name	G protein β-subunit 13F	Annotation symbol	CG10545
Feature type	protein_coding_gene	FlyBase ID	FBgn0001105
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	Gbeta13F, Gβ, G-beta, Gb13F, Gbb
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	13F16-13F16	Sequence location	X:15,754,159..15,756,919 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene G protein β-subunit 13F is referred to in FlyBase by the symbol Dmel\Gβ13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity. There is experimental evidence that it is involved in the biological process: asymmetric neuroblast division; actin filament organization. 17 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; embryonic neuroblast; mesothoracic tergum. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: G-protein beta WD-40 repeat; G-protein, beta subunit; Guanine nucleotide-binding protein, beta subunit; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult midgut, adult Malpighian tubules, adult fat body, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1627398_a_at completely aligns to an exonic region common to each of the 6 FlyBase-annotated transcript isoforms of Gbeta13F. Gene sequence location is X:15754159..15756919.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Gβ13F: G protein β subunit at 13F This gene encodes one isoform of the G protein β subunit in Drosophila melanogaster. After the G protein α has interacted with the effector, the β-γ subunits reassociate with the α subunit and bring the α subunit to its specific receptor.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	Sequence features BKN23019 HFA20247
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 13F16-13F16   Limits computationally determined from genome sequence between P{EP}BEST:RE35685EP1581&P{EP}sdEP1088 and P{EP}Gβ13FEP1071
Experimentally Determined Cytological Location
Cytogenetic map Notes References 13F-13F   (determined by in situ hybridisation)   (Yarfitz et al., 1988)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Gβ13F for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	EST data suggest additional 5' exon(s)
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Gbeta13F-RA FBtr0074107  NM_080351   1950   340 Gbeta13F-RB FBtr0074106  NM_167469   1562   340 Gbeta13F-RC FBtr0074108  NM_206739   1787   340 Gbeta13F-RD FBtr0074109  NM_206738   1859   340 Gbeta13F-RE FBtr0074110  NM_206737   2112   340 Gbeta13F-RF FBtr0074111  NM_206736   1871   340
Additional Transcript Data & Comments
Reported size (kB)	5.2, 4.2, 3.3, 3.0 (unknown); 3.1, 2.5, 2.0, 1.9 (northern blot) (Yarfitz et al., 1988)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Gbeta13F-PA   FBpp0073921   37.1   340   6.41     NP_525090   AAF48530 Gbeta13F-PB   FBpp0073920   37.1   340   6.41     NP_727907   AAN09370 Gbeta13F-PC   FBpp0089182   37.1   340   6.41     NP_996462   AAS65360 Gbeta13F-PD   FBpp0089183   37.1   340   6.41     NP_996461   AAS65361 Gbeta13F-PE   FBpp0089184   37.1   340   6.41     NP_996460   AAS65362 Gbeta13F-PF   FBpp0089185   37.1   340   6.41     NP_996459   AAS65363
Additional Polypeptide Data & Comments
Reported size (kDa)	340 (aa) (Yarfitz et al., 1988) 37 (kD observed) (Yarfitz et al., 1991)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • WD40/YVTN repeat-like-containing domain (IPR015943) WD40-repeat-containing domain (IPR017986) G-protein, beta subunit (IPR001632) WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) Guanine nucleotide-binding protein, beta subunit (IPR016346) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782) G-protein beta WD-40 repeat (IPR020472)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202783   AA246330   AA263358   AA391506   AA391831   AA539696   AA540347   AA540593   AA540984   AA695140   AA697129   AA698416   AA698666   AA816853   AA817214   AA820855   AA941398   AA948873   AA950129   AA952068   AA978844   AA978857   AA979187   AE014298 AAF48530   AE014298 AAN09370   AE014298 AAS65360   AE014298 AAS65361   AE014298 AAS65362   AE014298 AAS65363   AI062977   AI062989   AI114032   AI124260   AI258445   AI258525   AI260951   AI297015   AI387708   AI404061   AI406069   AI455266   AI456510   AI512643   AI515136   AQ025377   AW942735   AY058566 AAL13795   BF499840   BG634692   BG637531   BI161515   BI164346   BI166136   BI227898   BI229502   BI231808   BI232679   BI235161   BI237221   BI242689   BI242984   BI352884   BI352926   BI362738   BI363543   BI363784   BI364752   BI369621   BI374732   BI485400   BI567104   BI567722   BI575995   BI576983   BI586082   BI588117   BI634358   BI635597   BI635869   BI636062   BI636801   BI639164   BI639899   BI640818   BI641266   BP550643   BP550644   BP551097   BP551098   BP556240   BP556241   BP558265   BP558266   BP559795   BP559796   BQ103483   CA807799   CK657624   CK659121   CK661622   CL528239   CO153079   CO156354   CO187861   CO265901   CO269279   CO274984   CO278040   CO279650   CO295000   CO295587   CO295922   CO298790   CO299952   CO302226   CO302428   CO307322   CO310742   CO313795   CO316396   CO322057   CO325527   CO325998   CO326917   CO329082   CO335580   CO341240   DQ443371   EC066089   EC072984   EC074062   EC085209   EC086414   EC087586   EC198342   EC204705   EC209623   EC212930   EC231706   EC231969   EC236174   EC237002   EC240423   EC247370   EC249824   EC251505   EC254453   EC256783   EC263028   EC266310   EL872051   EL872300   EL872421   ES695673   ES695675   ES695690   ES696468   ES696469   ES696473   ES696480   ES696482   ES696483   ES696487   ES696494   ES696987   EV576824   EV585218   EV591480   GH948536   GH951348   GH952812   GH953424   GH953837   GH960067   GH963604   GH963686   GH964566   GH973741   GH973839   GH984901   M22567 AAB59247
UniProtKB/Swiss-Prot	P26308
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage | mid -- embryonic stage | late   organism   (Yarfitz et al., 1988) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage | early     (Yarfitz et al., 1988) embryonic stage -- adult stage     (Yarfitz et al., 1988) larval stage -- adult stage     (Yarfitz et al., 1988) radioisotope in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage   presumptive embryonic/larval central nervous system   (Yarfitz et al., 1991) pupal stage   brain   (Yarfitz et al., 1991) thoracico-abdominal ganglion   (Yarfitz et al., 1991) adult stage   ovary   (Yarfitz et al., 1991) thoracico-abdominal ganglion   (Yarfitz et al., 1991) adult brain cortex   (Yarfitz et al., 1991)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference adult stage   thoracico-abdominal ganglion   (Yarfitz et al., 1991) adult brain cortex   (Yarfitz et al., 1991) mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
	A monoclonal antibody generated against Gβ13F protein also recognizes Gβ76C protein. The antibody stains the brain neuropil and cortex, the eye, and the thoracic ganglion; the staining in the brain neuropil and cortex, and thoracic ganglion is due to Gβ13F protein. (Yarfitz et al., 1991)
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0001105    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0001105 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0001105 expression level Developmental Stage   Expression Level embryo 00-02hr    10347 embryo 02-04hr    14204 embryo 04-06hr    12224 embryo 06-08hr    11488 embryo 08-10hr    13113 embryo 10-12hr    16816 embryo 12-14hr    11147 embryo 14-16hr    13749 embryo 16-18hr    11860 embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10347) embryo 02-04hr  (14204) embryo 04-06hr  (12224) embryo 06-08hr  (11488) embryo 08-10hr  (13113) embryo 10-12hr  (16816) embryo 12-14hr  (11147) embryo 14-16hr  (13749) embryo 16-18hr  (11860) embryo 18-20hr  (9333) embryo 20-22hr  (8191) embryo 22-24hr  (7549) larva L1  (6830) larva L2  (4506) larva L3 12hr old  (3559) larva L3 puffstage 1-2  (2557) larva L3 puffstage 3-6  (5649) larva L3 puffstage 7-9  (6985) white prepupae new  (8241) white prepupae 12hr  (7711) white prepupae 24hr  (8489) pupae 2d postWPP  (7792) pupae 3d postWPP  (5761) pupae 4d postWPP  (4026) adult male 01day  (3579) adult male 05day  (3805) adult male 30day  (3757) adult female 01day  (6087) adult female 05day  (7300) adult female 30day  (7067) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10347) embryo 02-04hr  (14204) embryo 04-06hr  (12224) embryo 06-08hr  (11488) embryo 08-10hr  (13113) embryo 10-12hr  (16816) embryo 12-14hr  (11147) embryo 14-16hr  (13749) embryo 16-18hr  (11860) embryo 18-20hr  (9333) embryo 20-22hr  (8191) embryo 22-24hr  (7549) larva L1  (6830) larva L2  (4506) larva L3 12hr old  (3559) larva L3 puffstage 1-2  (2557) larva L3 puffstage 3-6  (5649) larva L3 puffstage 7-9  (6985) white prepupae new  (8241) white prepupae 12hr  (7711) white prepupae 24hr  (8489) pupae 2d postWPP  (7792) pupae 3d postWPP  (5761) pupae 4d postWPP  (4026) adult male 01day  (3579) adult male 05day  (3805) adult male 30day  (3757) adult female 01day  (6087) adult female 05day  (7300) adult female 30day  (7067) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10347 embryo 02-04hr  (14204) embryo 04-06hr  (12224) embryo 06-08hr  (11488) embryo 08-10hr  (13113) embryo 10-12hr  (16816) embryo 12-14hr  (11147) embryo 14-16hr  (13749) embryo 16-18hr  (11860) embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10347 embryo 02-04hr    14204 embryo 04-06hr    12224 embryo 06-08hr    11488 embryo 08-10hr    13113 embryo 10-12hr    16816 embryo 12-14hr    11147 embryo 14-16hr    13749 embryo 16-18hr    11860 embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0001105 expression level Developmental Stage   Expression Level embryo 00-02hr    10347 embryo 02-04hr    14204 embryo 04-06hr    12224 embryo 06-08hr    11488 embryo 08-10hr    13113 embryo 10-12hr    16816 embryo 12-14hr    11147 embryo 14-16hr    13749 embryo 16-18hr    11860 embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10347) embryo 02-04hr  (14204) embryo 04-06hr  (12224) embryo 06-08hr  (11488) embryo 08-10hr  (13113) embryo 10-12hr  (16816) embryo 12-14hr  (11147) embryo 14-16hr  (13749) embryo 16-18hr  (11860) embryo 18-20hr  (9333) embryo 20-22hr  (8191) embryo 22-24hr  (7549) larva L1  (6830) larva L2  (4506) larva L3 12hr old  (3559) larva L3 puffstage 1-2  (2557) larva L3 puffstage 3-6  (5649) larva L3 puffstage 7-9  (6985) white prepupae new  (8241) white prepupae 12hr  (7711) white prepupae 24hr  (8489) pupae 2d postWPP  (7792) pupae 3d postWPP  (5761) pupae 4d postWPP  (4026) adult male 01day  (3579) adult male 05day  (3805) adult male 30day  (3757) adult female 01day  (6087) adult female 05day  (7300) adult female 30day  (7067) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10347) embryo 02-04hr  (14204) embryo 04-06hr  (12224) embryo 06-08hr  (11488) embryo 08-10hr  (13113) embryo 10-12hr  (16816) embryo 12-14hr  (11147) embryo 14-16hr  (13749) embryo 16-18hr  (11860) embryo 18-20hr  (9333) embryo 20-22hr  (8191) embryo 22-24hr  (7549) larva L1  (6830) larva L2  (4506) larva L3 12hr old  (3559) larva L3 puffstage 1-2  (2557) larva L3 puffstage 3-6  (5649) larva L3 puffstage 7-9  (6985) white prepupae new  (8241) white prepupae 12hr  (7711) white prepupae 24hr  (8489) pupae 2d postWPP  (7792) pupae 3d postWPP  (5761) pupae 4d postWPP  (4026) adult male 01day  (3579) adult male 05day  (3805) adult male 30day  (3757) adult female 01day  (6087) adult female 05day  (7300) adult female 30day  (7067) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10347 embryo 02-04hr  14204 embryo 04-06hr  12224 embryo 06-08hr  11488 embryo 08-10hr  13113 embryo 10-12hr  16816 embryo 12-14hr  11147 embryo 14-16hr  13749 embryo 16-18hr  11860 embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10347 embryo 02-04hr    14204 embryo 04-06hr    12224 embryo 06-08hr    11488 embryo 08-10hr    13113 embryo 10-12hr    16816 embryo 12-14hr    11147 embryo 14-16hr    13749 embryo 16-18hr    11860 embryo 18-20hr    9333 embryo 20-22hr    8191 embryo 22-24hr    7549 larva L1    6830 larva L2    4506 larva L3 12hr old    3559 larva L3 puffstage 1-2    2557 larva L3 puffstage 3-6    5649 larva L3 puffstage 7-9    6985 white prepupae new    8241 white prepupae 12hr    7711 white prepupae 24hr    8489 pupae 2d postWPP    7792 pupae 3d postWPP    5761 pupae 4d postWPP    4026 adult male 01day    3579 adult male 05day    3805 adult male 30day    3757 adult female 01day    6087 adult female 05day    7300 adult female 30day    7067 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0001105    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0001105 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult midgut, adult Malpighian tubules, adult fat body, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0001105 expression level Tissue   Expression Level Larval Central Nervous System    1522.4 Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules    1079.6 Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea    1349.325 Larval Carcass    798.85 Adult Head    635.4 Adult Eye    1289.35 Adult Brain    1502.4 Adult Thoracic-Abdominal Ganglion    1568.9 Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart    1364.3 Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1522.4) Larval Midgut  (638.4) Larval Hindgut  (902.5) Larval Malpighian Tubules  (1079.6) Larval Fat Body  (789.5) Larval Salivary Gland  (565.1) Larval Trachea  (1349.325) Larval Carcass  (798.85) Adult Head  (635.4) Adult Eye  (1289.35) Adult Brain  (1502.4) Adult Thoracic-Abdominal Ganglion  (1568.9) Adult Crop  (869.5) Adult Midgut    443.4 Adult Hindgut  (751.4) Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland  (672.7) Adult Heart  (1364.3) Adult VirginFemale Spermatheca  (587.4) Adult InseminatedFemale Spermatheca  522.9 Adult Ovary  (858.2) Adult Testis    347.7 Adult Male Accessory Gland  (547) Adult Carcass  (554) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1522.4) Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules  (1079.6) Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea  (1349.325) Larval Carcass    798.85 Adult Head    635.4 Adult Eye  (1289.35) Adult Brain  (1502.4) Adult Thoracic-Abdominal Ganglion  (1568.9) Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart  (1364.3) Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1522.4 Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules    1079.6 Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea    1349.325 Larval Carcass    798.85 Adult Head    635.4 Adult Eye    1289.35 Adult Brain    1502.4 Adult Thoracic-Abdominal Ganglion    1568.9 Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart    1364.3 Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0001105 expression level Tissue   Expression Level Larval Central Nervous System    1522.4 Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules    1079.6 Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea    1349.325 Larval Carcass    798.85 Adult Head    635.4 Adult Eye    1289.35 Adult Brain    1502.4 Adult Thoracic-Abdominal Ganglion    1568.9 Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart    1364.3 Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1522.4) Larval Midgut  638.4 Larval Hindgut  (902.5) Larval Malpighian Tubules  (1079.6) Larval Fat Body  789.5 Larval Salivary Gland  565.1 Larval Trachea  (1349.325) Larval Carcass  798.85 Adult Head  635.4 Adult Eye  (1289.35) Adult Brain  (1502.4) Adult Thoracic-Abdominal Ganglion  (1568.9) Adult Crop  (869.5) Adult Midgut    443.4 Adult Hindgut  751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland  672.7 Adult Heart  (1364.3) Adult VirginFemale Spermatheca  587.4 Adult InseminatedFemale Spermatheca  522.9 Adult Ovary  (858.2) Adult Testis    347.7 Adult Male Accessory Gland  547 Adult Carcass  554 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1522.4 Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules  1079.6 Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea  1349.325 Larval Carcass    798.85 Adult Head    635.4 Adult Eye  1289.35 Adult Brain  1502.4 Adult Thoracic-Abdominal Ganglion  1568.9 Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart  1364.3 Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1522.4 Larval Midgut    638.4 Larval Hindgut    902.5 Larval Malpighian Tubules    1079.6 Larval Fat Body    789.5 Larval Salivary Gland    565.1 Larval Trachea    1349.325 Larval Carcass    798.85 Adult Head    635.4 Adult Eye    1289.35 Adult Brain    1502.4 Adult Thoracic-Abdominal Ganglion    1568.9 Adult Crop    869.5 Adult Midgut    443.4 Adult Hindgut    751.4 Adult Malpighian Tubules    475.7 Adult Fat Body    447 Adult Salivary Gland    672.7 Adult Heart    1364.3 Adult VirginFemale Spermatheca    587.4 Adult InseminatedFemale Spermatheca    522.9 Adult Ovary    858.2 Adult Testis    347.7 Adult Male Accessory Gland    547 Adult Carcass    554 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    635.4   NA  Eye    1289.35   NA  Brain    1502.4   1522.4  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1568.9   NA  Crop    869.5   638.4  Midgut    443.4   902.5  Hindgut    751.4   1079.6  Malpighian Tubules    475.7   789.5  Fat Body    447   565.1  Salivary Gland    672.7   NA  Heart    1364.3   1349.325  Trachea    NA   NA  VirginFemale Spermatheca    587.4   NA  InseminatedFemale Spermatheca    522.9   NA  Ovary    858.2   NA  Testis    347.7   NA  Male Accessory Gland    547   798.85  Carcass    554 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001105 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10545-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Gβ13F Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive Gβ13Ff261 Gβ13FΔ1-96A semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 Gβ13FGD7011 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 Gβ13FGD7011 neuroanatomy defective | germline clone Gβ13Ff261 visible, with Scer\GAL4pnr-MD237 Gβ13FGD7011 wild-type Gβ13F+tSa Phenotype manifest in Allele EL neuron | germline clone Gβ13Ff261 embryonic/first instar larval cuticle | anterior | germline clone Gβ13FΔ1-96A embryonic/first instar larval cuticle | germline clone | posterior Gβ13FΔ1-96A embryonic neuroblast Gβ13Funspecified embryonic neuroblast & spindle | germ-line clone Gβ13FΔ1-96A embryonic neuroblast | germline clone Gβ13FΔ1-96A Gβ13Ff261 gastrula embryo | germline clone Gβ13Ff261 mesothoracic tergum, with Scer\GAL4pnr-MD237 Gβ13FGD7011 neuroblast | germline clone Gβ13FΔ15 Gβ13Ff261 spindle & neuroblast Gβ13Funspecified trichogen cell, with Scer\GAL4pnr-MD237 Gβ13FGD7011
Classical Alleles ( 8 )
For All Classical Alleles Show
Allele of Gβ13F Class Mutagen Stocks Known lesion Gβ13FEP1071 P-element activity 1 Yes Gβ13FKG08410 P-element activity 1 -- Gβ13Ff261 0 Yes Gβ13FGG01564 0 -- Gβ13FGG01743 0 -- Gβ13Funspecified 0 -- Gβ13FΔ1-96A P-element activity 0 Yes Gβ13FΔ15 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Gβ13F Class Mutagen Stocks Known lesion Gβ13FGD7011 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gβ13FHMS01455 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gβ13FJF01609 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gβ13FKK102923 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gβ13F+t9.8 in vitro construct - genomic fragment 0 Yes Gβ13F+tSa in vitro construct - genomic fragment 0 Yes Gβ13FScer\UAS.cFa in vitro construct - regulatory fusion 0 Yes Gβ13FScer\UAS.cHa in vitro construct - regulatory fusion 0 Yes Gβ13FScer\UAS.cUa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6251 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UAS-Gβ13F.?F} NA characterization construct P{Gβ13F+tSa} NA P{UAS-MirN-Gβ13F} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Gβ13FEP1071 NA P{Mae-UAS.6.11}B0016B0016 NA P{Mae-UAS.6.11}Gβ13FGG01564 NA P{Mae-UAS.6.11}Gβ13FGG01743 NA miscellaneous insertions P{SUPor-P}Gβ13FKG08410 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
actin filament organization inferred from mutant phenotype (Kiger et al., 2003) asymmetric neuroblast division inferred from mutant phenotype (Yu et al., 2003)
Cellular Component
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008) plasma membrane inferred from direct assay (Khanna et al., 2010)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from sequence or structural similarity with UniProtKB:O45040 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1992.5.1)
Biological Process
CV term Evidence References
apical protein localization traceable author statement (Betschinger and Knoblich, 2004) G-protein coupled receptor signaling pathway inferred from sequence or structural similarity with UniProtKB:O45040 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1992.5.1)
Cellular Component
CV term Evidence References
heterotrimeric G-protein complex inferred from sequence or structural similarity with UniProtKB:O45040 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1992.5.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Gβ13F allele Gene References Gβ13Funspecified baz (Yu et al., 2003) unspecified mGluRA (Bogdanik et al., 2004)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58892 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001105 DroID - A comprehensive database of gene and protein interactions. • FBgn0001105 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32544
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20505 Dere\GG17923 Dgri\GH12882 Dmoj\GI14221 Dper\GL18448 Dpse\GA23154 Dsec\GM22591 Dsim\GD17247 Dvir\GJ14659 Dwil\GK15234 Dyak\GE17230
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013997-PA Aedes aegypti (mosquito) AGAP005911-PA Anopheles gambiae (mosquito) AGAP005912-PA Anopheles gambiae (mosquito) XP_393976.2 Apis mellifera (honey bee) XP_001947878.1 Acyrthosiphon pisum (pea aphid) At4g34460.1 Arabidopsis thaliana (wall cress) 17943 Batrachochytrium dendrobatidis (chytrid fungus) 220697 Branchiostoma floridae (lancelet) XP_001902409.1 Brugia malayi (roundworm nematode) BGIBMGA004626-PA Bombyx mori (silk worm) ENSBTAP00000042481 Bos taurus (bovine) CAL0002035 Candida albicans (a form of yeast) CN27655 Caenorhabditis brenneri (small nematode) CBP00625 Caenorhabditis briggsae (nematode) CE02186 Caenorhabditis elegans (worm) ENSCAFP00000031022 Canis familiaris (dog) CAGL0L02761g Candida glabrata (haploid yeast) ENSCINP00000007802 Ciona intestinalis (sea squirt) JA01787 Caenorhabditis japonica (nematode) cn04251 Cryptococcus neoformans (yeast-like fungus) CPIJ007403 Culex pipens (mosquito) ENSCPOP00000004992 Cavia porcellus (guinea pig) RP24965 Caenorhabditis remanei (nematode) ENSCSAVP00000015141 Ciona savignyi (sedentary tunicate) 124853 Capitella spl (polychaete worm) DDB0252679 Dictyostelium discoideum (amoeba) DEHA2C16368g Debaryomyces Hansenii (yeast) 304794 Daphnia pulex (daphnia) ENSDARP00000018443 Danio rerio (zebra fish) ENSDARP00000079424 Danio rerio (zebra fish) ENSECAP00000019413 Equus caballus (horse) XP_652747 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000016084 Gymnopilus aculeatus (mushroom) ENSGALP00000014596 Gallus gallus (chicken) 75178 Hypsipyla robusta (cedar shoot borer) ENSP00000367872 Homo sapiens (human) ISCW009711-PA Ixodes scapularis (deer tick) 236462 Lottia gigantea (owl limpet) 38561 Monocosta brevicollis (choanoflagellate) ENSMODP00000008530 Monodelphis domestica (gray opossum) ENSMMUP00000002526 Macaca mulatta (rhesus monkey) ENSMUSP00000030940 Mus musculus (house mouse) 105798 Nematostella vectensis (starlet anemone) XP_001599306.1 Nasonia vitripennis (wasp) ENSOANP00000007438 Ornithorynchus anatinus (platypus) ENSOANP00000010184 Ornithorynchus anatinus (platypus) ENSORLP00000004503 Oryzias latipes (japanese killifish) LOC_Os03g46650.1 Oryza sativa (asian rice) PHUM004464-PA Pediculus humanus (human body louse) PP00600 Pristionchus pacificus (nematode) 113533 Physcomitrella patens (moss) ENSPPYP00000002307 Pongo pygmaeus (orangutan) 71703 Phytophthora ramorum (sudden oak death pathogen) 108890 Phytophthora sojae (root rot pathogen) 712950 Populus trichocarpa (black cottonwood) ENSPTRP00000033383 Pan troglodytes (chimpanzee) ENSRNOP00000044340 Rattus norvegicus (norway rat) 141535 Sorghum bicolor (sorghum) YOR212W Saccharomyces cerevisiae (budding yeast) Smp_010230.2 Schistosoma mansoni (trematode parasite) SPBC32H8.07 Schizosaccharomyces pombe (fission yeast) XP_001178873.1 Strongylocentrotus purpuratus (purple sea urchin) 64010 Trichoplax adhaerens (metazoa) XP_970131.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017796 Tetraodon nigroviridis (green spotted pufferfish) 37124 Thalassiosira pseudonana (marine diatom) ENSTRUP00000001674 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000015774 Xenopus tropicalis (frog) YALI0E01364g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18102 NV18567 LH15351 ISCW009711 FBgn0234708 FBgn0217239 FBgn0201866 FBgn0188810 FBgn0177461 JGI_V11_304794 FBgn0244556 FBgn0156049 FBgn0136974 FBgn0120361 FBgn0110143 FBgn0097511 CPIJ016404 CPIJ016403 CPIJ007402 CPIJ007403 BGIBMGA004626 ACYPI008947 GB15307 AGAP005912 AGAP005911 AAEL013997 AAEL013991 PHUM046980 PHUM437580 PHUM521670 GLEAN_14882
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	10131 w1118 P{EP}Gβ13FEP1071 31134 y1 v1; P{TRiP.JF01609}attP2 16469 y1 P{SUPor-P}Gβ13FKG08410/FM7c 35041 y1 sc* v1; P{TRiP.HMS01455}attP2
VDRC	v100011 P{KK102923}VIE-260B v31257 w1118; P{GD7011}v31257/TM3
Genomic Clones ( 2 )
	BACR22H11 BACR25C18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 164 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD25526
Other clones	DPiM_LD25526
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT14606 AT30990 GH02373 GH02386 GH10702 GH18317 GH23650 GH26255 GM02306 GM09151 GM21171 GM21311 HL04446 HL05434 LD03109 LD05173 LD06458 LD10533 LD10726 LD17990 LD19809 LD20033 LD20327 LD20710 LD24767 LD27547 LD28664 LD29111 LD33013 LD33032 LD33481 LD36552 LD44569 LD46835 LP01650 LP01745 LP05003 LP11164 LP16647 LP21244 LP24070 RE01020 RE04008 RE06167 RE24341 RE25283 RE27294 RE28782 RE30972 RE33409 RE40087 RE40496 RE47387 RE48384 RE48730 RE49928 RE55863 RE62404 RE68718 RH25826 RH29185 RH32439 RH33709 RH36954 RH38281 RH38402 SD15590 SD16987 SD17394 SD17629 SD18626 SD21642 SD22606 SD23823 SD24488
Other clones	21422 28066 34748 50715 55917 69726 77137 78668 79864 100048 104806 148398 161047 179846 214275.37 214383.39 214535.38 522031 527761 AI124260 CK01.7B.D5 CK01.123C.G3 CK01.143A.E5 Dmel_dig_007909_0707_1163 Dmel_dig_019718_0647_0875 Dmel_neb_012754_0382_2577 EK034339 EK094026 EK116119 EK128602 EK135554 EK144411 EK173853 EK177020 EK183703 EK184129 EK187124 EK196722 EK208131 EK210759 EK212260 EK222418 EK234104 EK254341 EK264830 EK292009 EN01229 EN07913 EN10752 EP03040 EP04955 EP12109 ESG019c.E21_F02 FGM208C10 FGM210H08 FGM302C02 FGM314A04 FGM323A02 IP04042 IP04242 IP04342 LD22392 RC0-DP0004-150700-011-A12 RC0-DP0004-150700-011-B01 RC0-DP0004-150700-011-B06 RC0-DP0004-150700-011-C12 RC0-DP0004-150700-011-D02 RC0-DP0004-150700-011-D09 RC0-DP0004-150700-011-H10 RC0-DP0004-150700-012-A07 RC0-DP0004-150700-012-D06 RC0-DP0004-150700-012-F11 RC0-DP0004-150700-012-G05 RC0-DP0005-150700-011-H11 RP004123396 RP004129558 RP004138757 RP004157917 RP004198219 RP004375348 RP004376391 RP004502171 RP004510940 RP004512352 RP004525081 RP004549415 UUGC0889
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0001105 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32544
Antibody Information
	monoclonal (Yarfitz et al., 1991)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Gβ13F CG10545 (Wang, 1999.11)
Source for database merge of
Additional comments	"l(1)G0369" may affect "Gβ13F". (Peter et al., 2002)
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in Kc167 and S2R+ cells: increased or polarized (uneven) accumulation of F-actin. (Kiger et al., 2003) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) dsRNA made from templates generated with primers against this gene tested in a cl-8 cell reporter assay to examine any role of Gβ13F in the hh signalling pathway. (Lum, 2003) Gβ13F mutant show defects in both spindle orientation and determinant localisation in neuroblasts. (Schaefer et al., 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080351 NM_167469 NM_206736 NM_206737 NM_206738 NM_206739 RefSeq (Proteins) • NP_525090 NP_727907 NP_996459 NP_996460 NP_996461 NP_996462 DDBJ / EMBL / GenBank • AA941398 AAB59247 AAF48530 AAL13795 AAN09370 AAS65360 AAS65361 AAS65362 AAS65363 AI124260 AQ025377 AW942735 AY058566 CL528239 M22567 Entrez Gene - A searchable database of RefSeq genes. • 32544 UniProtKB/Swiss-Prot • P26308
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • WD40/YVTN repeat-like-containing domain (IPR015943) WD40-repeat-containing domain (IPR017986) G-protein, beta subunit (IPR001632) WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) Guanine nucleotide-binding protein, beta subunit (IPR016346) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782) G-protein beta WD-40 repeat (IPR020472)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58892 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001105 DroID - A comprehensive database of gene and protein interactions. • FBgn0001105 DRSC - Results from RNAi screens. • FBgn0001105 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001105 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10545-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0001105 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32544 InParanoid A subset of ortholog calls from InParanoid. • AAEL013997-PA Aedes aegypti (mosquito) AGAP005911-PA Anopheles gambiae (mosquito) AGAP005912-PA Anopheles gambiae (mosquito) XP_393976.2 Apis mellifera (honey bee) XP_001947878.1 Acyrthosiphon pisum (pea aphid) At4g34460.1 Arabidopsis thaliana (wall cress) 17943 Batrachochytrium dendrobatidis (chytrid fungus) 220697 Branchiostoma floridae (lancelet) XP_001902409.1 Brugia malayi (roundworm nematode) BGIBMGA004626-PA Bombyx mori (silk worm) ENSBTAP00000042481 Bos taurus (bovine) CAL0002035 Candida albicans (a form of yeast) CN27655 Caenorhabditis brenneri (small nematode) CBP00625 Caenorhabditis briggsae (nematode) CE02186 Caenorhabditis elegans (worm) ENSCAFP00000031022 Canis familiaris (dog) CAGL0L02761g Candida glabrata (haploid yeast) ENSCINP00000007802 Ciona intestinalis (sea squirt) JA01787 Caenorhabditis japonica (nematode) cn04251 Cryptococcus neoformans (yeast-like fungus) CPIJ007403 Culex pipens (mosquito) ENSCPOP00000004992 Cavia porcellus (guinea pig) RP24965 Caenorhabditis remanei (nematode) ENSCSAVP00000015141 Ciona savignyi (sedentary tunicate) 124853 Capitella spl (polychaete worm) DDB0252679 Dictyostelium discoideum (amoeba) DEHA2C16368g Debaryomyces Hansenii (yeast) 304794 Daphnia pulex (daphnia) ENSDARP00000018443 Danio rerio (zebra fish) ENSDARP00000079424 Danio rerio (zebra fish) ENSECAP00000019413 Equus caballus (horse) XP_652747 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000016084 Gymnopilus aculeatus (mushroom) ENSGALP00000014596 Gallus gallus (chicken) 75178 Hypsipyla robusta (cedar shoot borer) ENSP00000367872 Homo sapiens (human) ISCW009711-PA Ixodes scapularis (deer tick) 236462 Lottia gigantea (owl limpet) 38561 Monocosta brevicollis (choanoflagellate) ENSMODP00000008530 Monodelphis domestica (gray opossum) ENSMMUP00000002526 Macaca mulatta (rhesus monkey) ENSMUSP00000030940 Mus musculus (house mouse) 105798 Nematostella vectensis (starlet anemone) XP_001599306.1 Nasonia vitripennis (wasp) ENSOANP00000007438 Ornithorynchus anatinus (platypus) ENSOANP00000010184 Ornithorynchus anatinus (platypus) ENSORLP00000004503 Oryzias latipes (japanese killifish) LOC_Os03g46650.1 Oryza sativa (asian rice) PHUM004464-PA Pediculus humanus (human body louse) PP00600 Pristionchus pacificus (nematode) 113533 Physcomitrella patens (moss) ENSPPYP00000002307 Pongo pygmaeus (orangutan) 71703 Phytophthora ramorum (sudden oak death pathogen) 108890 Phytophthora sojae (root rot pathogen) 712950 Populus trichocarpa (black cottonwood) ENSPTRP00000033383 Pan troglodytes (chimpanzee) ENSRNOP00000044340 Rattus norvegicus (norway rat) 141535 Sorghum bicolor (sorghum) YOR212W Saccharomyces cerevisiae (budding yeast) Smp_010230.2 Schistosoma mansoni (trematode parasite) SPBC32H8.07 Schizosaccharomyces pombe (fission yeast) XP_001178873.1 Strongylocentrotus purpuratus (purple sea urchin) 64010 Trichoplax adhaerens (metazoa) XP_970131.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017796 Tetraodon nigroviridis (green spotted pufferfish) 37124 Thalassiosira pseudonana (marine diatom) ENSTRUP00000001674 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000015774 Xenopus tropicalis (frog) YALI0E01364g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32544 modMine - Data generated by the modENCODE project. • FBgn0001105 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18102 NV18567 LH15351 ISCW009711 FBgn0234708 FBgn0217239 FBgn0201866 FBgn0188810 FBgn0177461 JGI_V11_304794 FBgn0244556 FBgn0156049 FBgn0136974 FBgn0120361 FBgn0110143 FBgn0097511 CPIJ016404 CPIJ016403 CPIJ007402 CPIJ007403 BGIBMGA004626 ACYPI008947 GB15307 AGAP005912 AGAP005911 AAEL013997 AAEL013991 PHUM046980 PHUM437580 PHUM521670 GLEAN_14882
Synonyms & Secondary IDs ( 18 )
Reported As
Symbol Synonym	anon-EST:Liang-1.22   CG10545 (Legube et al., 2006, Grieder et al., 2007, Keleman et al., 2009.8.5, Hughes et al., 2008, Khanna et al., 2010, Ni et al., 2008, Ni et al., 2011.7.19, Cammarato et al., 2011) clone 1.22 (Liang and Biggin, 1998) dgβ (Buchner, 1991) Gβ (Montell, 2000) G b13F (Peter et al., 2002) Gb13F (Schaefer et al., 2001, Boyle and Berg, 2007) Gbb (Yarfitz, 1993.1.26, Yarfitz et al., 1991) G-beta (Beall et al., 2002, Lipsick, 2000.9.11, Manak et al., 2002) Gbeta13F (Lum, 2003, Bier and Bodmer, 2004, Reiter et al., 2001, Giot et al., 2003, Grieder et al., 2007, Magalhaes et al., 2007) Gβ (Bardin et al., 2004, van der Bliek and Meyerowitz, 1991, Egger-Adam and Katanaev, 2010, Yamashita et al., 2005) Gβ13F (Fuse et al., 2003, Egger-Adam and Katanaev, 2010, Stuart et al., 2007, Nurminsky, 2007, Bogdanik et al., 2004, Bakal et al., 2007, Wang et al., 2005, Hampoelz et al., 2005, Zelhof et al., 2003, David et al., 2005, Yi et al., 2008, Kunwar et al., 2008, Hughes et al., 2008, Speicher et al., 2008, Katanayeva et al., 2010, Boyle et al., 2010, Kitajima et al., 2010) G-βb
Name Synonym	Gβ brain (Yarfitz et al., 1991) G protein beta-subunit 13F (Cammarato et al., 2011) G-protein β 13F (Liang and Biggin, 1998) G protein β subunit (van der Bliek and Meyerowitz, 1991) G protein β-subunit 13F (Khanna et al., 2010)
Secondary FlyBase IDs
References ( 77 )
Generate a list of	All references relating to this gene ( 77 )
List References by type	Research paper  ( 33 ) Supplementary material  ( 11 ) Review  ( 10 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 7 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Conference report  ( 1 ) Curated genome annotation  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 4 )
	Boyle et al., 2010, Dev. Biol. 346(1): 68--79 Division of labor: Subsets of dorsal-appendage-forming cells control the shape of the entire tube. [FBrf0211761] Egger-Adam and Katanaev, 2010, Dev. Dyn. 239(1): 168--183 The trimeric G protein Go inflicts a double impact on axin in the Wnt/frizzled signaling pathway. [FBrf0209618] Katanayeva et al., 2010, PLoS ONE 5(8): e12331 Competing activities of heterotrimeric g proteins in Drosophila wing maturation. [FBrf0211718] Kitajima et al., 2010, Dev. Biol. 347(1): 9--23 Progenitor properties of symmetrically dividing Drosophila neuroblasts during embryonic and larval development. [FBrf0211968] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...