• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\GstD1

General Information
Symbol	Dmel\GstD1	Species	D. melanogaster
Name	Glutathione S transferase D1	Annotation symbol	CG10045
Feature type	protein_coding_gene	FlyBase ID	FBgn0001149
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	Gst, DmGST1, GST-1, DmGSTD1, Gst1-1, DmGSTD1-1, DmGST-1, GST1
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87B8-87B8	Sequence location	3R:8,193,269..8,194,987 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Glutathione S transferase D1 is referred to in FlyBase by the symbol Dmel\GstD1 (CG10045, FBgn0001149). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: DDT-dehydrochlorinase activity; glutathione transferase activity. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase/chloride channel, C-terminal; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628353_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of GstD1. Gene sequence location is 3R:8193269..8194987.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Transgenic Constructs P{GstD1-lacZ.S}
FB2012_01	Sequence features BKN32645 HFA16683
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87B8-87B8   Limits computationally determined from genome sequence between P{PZ}svp07842 and P{lacW}Vha55j2E9
Experimentally Determined Cytological Location
Cytogenetic map Notes References 87B-87B   (determined by in situ hybridisation)   (Toung and Tu, 1992) 87B-87B   (determined by in situ hybridisation)   (Toung et al., 1991) 87B8-87B9   (determined by in situ hybridisation)   (Toung et al., 1990)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\GstD1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) GstD1-RA FBtr0082607  NM_079602   822   209 GstD1-RB FBtr0100410  NM_001038953   1149   209
Additional Transcript Data & Comments
Reported size (kB)	0.764 (longest cDNA) (Toung et al., 1990)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein GstD1-PA   FBpp0082077   23.9   209   7.33     NP_524326   AAF54786 GstD1-PB   FBpp0099824   23.9   209   7.33     NP_001034042   ABC66168
Additional Polypeptide Data & Comments
Reported size (kDa)	209 (aa); 24 (kD predicted) (Toung et al., 1990) 209 (aa) (Toung et al., 1993, Toung et al., 1991)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, N-terminal (IPR004045) Glutathione S-transferase, C-terminal (IPR004046) Glutathione S-transferase, C-terminal-like (IPR010987) Thioredoxin-like fold (IPR012336) Glutathione S-transferase/chloride channel, C-terminal (IPR017933)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440129   AA735823   AA803543   AA821086   AE014297 AAF54786   AE014297 ABC66168   AI063567   AI063572   AI106741   AI108593   AI114250   AI237926   AI257606   AI293639   AI297266   AI297287   AI297766   AI297879   AI386700   AI402955   AI404482   AI404652   AI405136   AI405646   AI945315   AI946965   AY121705 AAM52032   AY231942   BE975707   BE975708   BE977984   BE978635   BG633323   BG639457   BI166232   BI166856   BI173431   BI173616   BI213626   BI237061   BI238266   BI352575   BI353076   BI354100   BI355017   BI355793   BI357499   BI370266   BI482418   BI482515   BI484677   BI484784   BI485678   BI563703   BI563792   BI563953   BI565138   BI565541   BI566816   BI570733   BI571145   BI571169   BI572719   BI572733   BI573998   BI573999   BI574228   BI578985   BI583977   BI584943   BI586842   BI590866   BI604676   BI608103   BI612130   BI612879   BI617087   BI623789   BI625973   BI626733   BI629634   BI631598   BI634629   BP541885   BP544840   BP544841   BP546841   BP553235   BP554729   BP554730   BP557196   BP559624   BP559625   BQ103115   BT023393   BT030973   BX007504   BX048001   BX048902   BX049011   BX050759   BX053230   BX057827   BX059599   CA804599   CA804672   CK658435   CK660955   CO154293   CO154717   CO155352   CO155494   CO157108   CO181086   CO182114   CO184508   CO184907   CO185084   CO192047   CO192567   CO195447   CO268026   CO270030   CO270166   CO276157   CO308155   CO314771   CO336825   CO337139   CO337242   CO338494   CO338843   CR938483   EC059545   EC065235   EC071260   EC075652   EC077644   EC088328   EC208709   EC220184   EC220333   EC226265   EC261314   EC262006   EC262929   EC264265   EC265170   EC265362   EC265607   EC266036   EC267142   EC267372   EV575116   EV575654   EV575776   EV576524   EV576652   EV577044   EV577315   EV578576   EV578967   EV581003   EV581321   EV582190   EV582355   EV584401   EV585651   EV585794   EV592199   EV593605   EV596767   EV597185   EV599102   EV599879   EV599914   GH756391   GH757890   GH774189   GH781017   GH792641   GH798444   GH804943   GH808055   GH821441   GH827533   GH829494   GH833809   GH837168   GH838998   GH840311   GH843290   GH847243   GH848916   GH855644   GH860516   GH860958   GH861000   GH871692   GH880679   GH881014   GH884665   GH885508   GH896211   GH896373   GH897284   GH902629   GH904602   GH908681   GH920674   GH920961   GH922036   GH933221   GH934140   M97702   S51044   X14233 CAA32449
UniProtKB/Swiss-Prot	P20432
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11   posterior midgut primordium   (Nakamura et al., 1999) anterior midgut primordium   (Nakamura et al., 1999) embryonic stage 12 -- 15   midgut primordium | restricted   (Nakamura et al., 1999) Comment:stripe of expression embryonic stage 14 -- 15   proventriculus primordium   (Nakamura et al., 1999) embryonic stage 15   proventriculus inner layer primordium   (Nakamura et al., 1999) epithelium of embryonic hindgut | anterior   (Nakamura et al., 1999) epithelium of embryonic/larval midgut primordium | restricted   (Nakamura et al., 1999) embryonic stage 16   embryonic hindgut | restricted   (Nakamura et al., 1999) Comment:point where Malpighian tubules open into hindgut northern blot Stage Tissue/Position (including subcellular localization) Reference adult stage     (Toung et al., 1993)
Additional Descriptive Data
	GstD1 is the most abundant Gst mRNA in adults. (Toung et al., 1993)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0001149    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0001149 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0001149 expression level Developmental Stage   Expression Level embryo 00-02hr    37656 embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr    10360 embryo 16-18hr    9304 embryo 18-20hr    10600 embryo 20-22hr    16776 embryo 22-24hr    20307 larva L1    23561 larva L2    43313 larva L3 12hr old    50536 larva L3 puffstage 1-2    32493 larva L3 puffstage 3-6    23563 larva L3 puffstage 7-9    21731 white prepupae new    23612 white prepupae 12hr    17530 white prepupae 24hr    25761 pupae 2d postWPP    30514 pupae 3d postWPP    20985 pupae 4d postWPP    16035 adult male 01day    20314 adult male 05day    17697 adult male 30day    21442 adult female 01day    22551 adult female 05day    30099 adult female 30day    30083 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr  (932) embryo 04-06hr  (761) embryo 06-08hr  (1207) embryo 08-10hr  (1941) embryo 10-12hr  (6584) embryo 12-14hr  (6050) embryo 14-16hr  (10360) embryo 16-18hr  (9304) embryo 18-20hr  (10600) embryo 20-22hr  (16776) embryo 22-24hr  (20307) larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  (17530) white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  (16035) adult male 01day  (20314) adult male 05day  (17697) adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr  (1941) embryo 10-12hr  (6584) embryo 12-14hr  (6050) embryo 14-16hr  (10360) embryo 16-18hr  (9304) embryo 18-20hr  (10600) embryo 20-22hr  (16776) embryo 22-24hr  (20307) larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  (17530) white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  (16035) adult male 01day  (20314) adult male 05day  (17697) adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr  10360 embryo 16-18hr    9304 embryo 18-20hr  10600 embryo 20-22hr  (16776) embryo 22-24hr  (20307) larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  (17530) white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  (16035) adult male 01day  (20314) adult male 05day  (17697) adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    37656 embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr    10360 embryo 16-18hr    9304 embryo 18-20hr    10600 embryo 20-22hr    16776 embryo 22-24hr    20307 larva L1    23561 larva L2    43313 larva L3 12hr old    50536 larva L3 puffstage 1-2    32493 larva L3 puffstage 3-6    23563 larva L3 puffstage 7-9    21731 white prepupae new    23612 white prepupae 12hr    17530 white prepupae 24hr    25761 pupae 2d postWPP    30514 pupae 3d postWPP    20985 pupae 4d postWPP    16035 adult male 01day    20314 adult male 05day    17697 adult male 30day    21442 adult female 01day    22551 adult female 05day    30099 adult female 30day    30083 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0001149 expression level Developmental Stage   Expression Level embryo 00-02hr    37656 embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr    10360 embryo 16-18hr    9304 embryo 18-20hr    10600 embryo 20-22hr    16776 embryo 22-24hr    20307 larva L1    23561 larva L2    43313 larva L3 12hr old    50536 larva L3 puffstage 1-2    32493 larva L3 puffstage 3-6    23563 larva L3 puffstage 7-9    21731 white prepupae new    23612 white prepupae 12hr    17530 white prepupae 24hr    25761 pupae 2d postWPP    30514 pupae 3d postWPP    20985 pupae 4d postWPP    16035 adult male 01day    20314 adult male 05day    17697 adult male 30day    21442 adult female 01day    22551 adult female 05day    30099 adult female 30day    30083 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr  (932) embryo 04-06hr  (761) embryo 06-08hr  (1207) embryo 08-10hr  (1941) embryo 10-12hr  (6584) embryo 12-14hr  (6050) embryo 14-16hr  (10360) embryo 16-18hr  (9304) embryo 18-20hr  (10600) embryo 20-22hr  (16776) embryo 22-24hr  (20307) larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  (17530) white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  (16035) adult male 01day  (20314) adult male 05day  (17697) adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr  1941 embryo 10-12hr  (6584) embryo 12-14hr  (6050) embryo 14-16hr  (10360) embryo 16-18hr  (9304) embryo 18-20hr  (10600) embryo 20-22hr  (16776) embryo 22-24hr  (20307) larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  (17530) white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  (16035) adult male 01day  (20314) adult male 05day  (17697) adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (37656) embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr  10360 embryo 16-18hr    9304 embryo 18-20hr  10600 embryo 20-22hr  16776 embryo 22-24hr  20307 larva L1  (23561) larva L2  (43313) larva L3 12hr old  (50536) larva L3 puffstage 1-2  (32493) larva L3 puffstage 3-6  (23563) larva L3 puffstage 7-9  (21731) white prepupae new  (23612) white prepupae 12hr  17530 white prepupae 24hr  (25761) pupae 2d postWPP  (30514) pupae 3d postWPP  (20985) pupae 4d postWPP  16035 adult male 01day  20314 adult male 05day  17697 adult male 30day  (21442) adult female 01day  (22551) adult female 05day  (30099) adult female 30day  (30083) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    37656 embryo 02-04hr    932 embryo 04-06hr    761 embryo 06-08hr    1207 embryo 08-10hr    1941 embryo 10-12hr    6584 embryo 12-14hr    6050 embryo 14-16hr    10360 embryo 16-18hr    9304 embryo 18-20hr    10600 embryo 20-22hr    16776 embryo 22-24hr    20307 larva L1    23561 larva L2    43313 larva L3 12hr old    50536 larva L3 puffstage 1-2    32493 larva L3 puffstage 3-6    23563 larva L3 puffstage 7-9    21731 white prepupae new    23612 white prepupae 12hr    17530 white prepupae 24hr    25761 pupae 2d postWPP    30514 pupae 3d postWPP    20985 pupae 4d postWPP    16035 adult male 01day    20314 adult male 05day    17697 adult male 30day    21442 adult female 01day    22551 adult female 05day    30099 adult female 30day    30083 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0001149    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0001149 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0001149 expression level Tissue   Expression Level Larval Central Nervous System    1462.775 Larval Midgut    1832.6 Larval Hindgut    3499.6 Larval Malpighian Tubules    4359.7 Larval Fat Body    4926.7 Larval Salivary Gland    8435.7 Larval Trachea    4977.8 Larval Carcass    4100.95 Adult Head    2603.1 Adult Eye    1569.075 Adult Brain    1727.6 Adult Thoracic-Abdominal Ganglion    2109.1 Adult Crop    4093.8 Adult Midgut    3151 Adult Hindgut    3481.1 Adult Malpighian Tubules    4079.5 Adult Fat Body    1241.4 Adult Salivary Gland    2372.1 Adult Heart    2356.925 Adult VirginFemale Spermatheca    3220.8 Adult InseminatedFemale Spermatheca    3217.4 Adult Ovary    2887.9 Adult Testis    1885.6 Adult Male Accessory Gland    3478.1 Adult Carcass    2692.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1462.775) Larval Midgut  (1832.6) Larval Hindgut  (3499.6) Larval Malpighian Tubules  (4359.7) Larval Fat Body  (4926.7) Larval Salivary Gland  (8435.7) Larval Trachea  (4977.8) Larval Carcass  (4100.95) Adult Head  (2603.1) Adult Eye  (1569.075) Adult Brain  (1727.6) Adult Thoracic-Abdominal Ganglion  (2109.1) Adult Crop  (4093.8) Adult Midgut  (3151) Adult Hindgut  (3481.1) Adult Malpighian Tubules  (4079.5) Adult Fat Body  (1241.4) Adult Salivary Gland  (2372.1) Adult Heart  (2356.925) Adult VirginFemale Spermatheca  (3220.8) Adult InseminatedFemale Spermatheca  (3217.4) Adult Ovary  (2887.9) Adult Testis  (1885.6) Adult Male Accessory Gland  (3478.1) Adult Carcass  (2692.8) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1462.775) Larval Midgut  (1832.6) Larval Hindgut  (3499.6) Larval Malpighian Tubules  (4359.7) Larval Fat Body  (4926.7) Larval Salivary Gland  (8435.7) Larval Trachea  (4977.8) Larval Carcass  (4100.95) Adult Head  (2603.1) Adult Eye  (1569.075) Adult Brain  (1727.6) Adult Thoracic-Abdominal Ganglion  (2109.1) Adult Crop  (4093.8) Adult Midgut  (3151) Adult Hindgut  (3481.1) Adult Malpighian Tubules  (4079.5) Adult Fat Body  (1241.4) Adult Salivary Gland  (2372.1) Adult Heart  (2356.925) Adult VirginFemale Spermatheca  (3220.8) Adult InseminatedFemale Spermatheca  (3217.4) Adult Ovary  (2887.9) Adult Testis  (1885.6) Adult Male Accessory Gland  (3478.1) Adult Carcass  (2692.8) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1462.775 Larval Midgut    1832.6 Larval Hindgut    3499.6 Larval Malpighian Tubules    4359.7 Larval Fat Body    4926.7 Larval Salivary Gland    8435.7 Larval Trachea    4977.8 Larval Carcass    4100.95 Adult Head    2603.1 Adult Eye    1569.075 Adult Brain    1727.6 Adult Thoracic-Abdominal Ganglion    2109.1 Adult Crop    4093.8 Adult Midgut    3151 Adult Hindgut    3481.1 Adult Malpighian Tubules    4079.5 Adult Fat Body    1241.4 Adult Salivary Gland    2372.1 Adult Heart    2356.925 Adult VirginFemale Spermatheca    3220.8 Adult InseminatedFemale Spermatheca    3217.4 Adult Ovary    2887.9 Adult Testis    1885.6 Adult Male Accessory Gland    3478.1 Adult Carcass    2692.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0001149 expression level Tissue   Expression Level Larval Central Nervous System    1462.775 Larval Midgut    1832.6 Larval Hindgut    3499.6 Larval Malpighian Tubules    4359.7 Larval Fat Body    4926.7 Larval Salivary Gland    8435.7 Larval Trachea    4977.8 Larval Carcass    4100.95 Adult Head    2603.1 Adult Eye    1569.075 Adult Brain    1727.6 Adult Thoracic-Abdominal Ganglion    2109.1 Adult Crop    4093.8 Adult Midgut    3151 Adult Hindgut    3481.1 Adult Malpighian Tubules    4079.5 Adult Fat Body    1241.4 Adult Salivary Gland    2372.1 Adult Heart    2356.925 Adult VirginFemale Spermatheca    3220.8 Adult InseminatedFemale Spermatheca    3217.4 Adult Ovary    2887.9 Adult Testis    1885.6 Adult Male Accessory Gland    3478.1 Adult Carcass    2692.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1462.775) Larval Midgut  (1832.6) Larval Hindgut  (3499.6) Larval Malpighian Tubules  (4359.7) Larval Fat Body  (4926.7) Larval Salivary Gland  (8435.7) Larval Trachea  (4977.8) Larval Carcass  (4100.95) Adult Head  (2603.1) Adult Eye  (1569.075) Adult Brain  (1727.6) Adult Thoracic-Abdominal Ganglion  (2109.1) Adult Crop  (4093.8) Adult Midgut  (3151) Adult Hindgut  (3481.1) Adult Malpighian Tubules  (4079.5) Adult Fat Body  (1241.4) Adult Salivary Gland  (2372.1) Adult Heart  (2356.925) Adult VirginFemale Spermatheca  (3220.8) Adult InseminatedFemale Spermatheca  (3217.4) Adult Ovary  (2887.9) Adult Testis  (1885.6) Adult Male Accessory Gland  (3478.1) Adult Carcass  (2692.8) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1462.775 Larval Midgut  (1832.6) Larval Hindgut  (3499.6) Larval Malpighian Tubules  (4359.7) Larval Fat Body  (4926.7) Larval Salivary Gland  (8435.7) Larval Trachea  (4977.8) Larval Carcass  (4100.95) Adult Head  (2603.1) Adult Eye  1569.075 Adult Brain  (1727.6) Adult Thoracic-Abdominal Ganglion  (2109.1) Adult Crop  (4093.8) Adult Midgut  (3151) Adult Hindgut  (3481.1) Adult Malpighian Tubules  (4079.5) Adult Fat Body  1241.4 Adult Salivary Gland  (2372.1) Adult Heart  (2356.925) Adult VirginFemale Spermatheca  (3220.8) Adult InseminatedFemale Spermatheca  (3217.4) Adult Ovary  (2887.9) Adult Testis  (1885.6) Adult Male Accessory Gland  (3478.1) Adult Carcass  (2692.8) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1462.775 Larval Midgut    1832.6 Larval Hindgut    3499.6 Larval Malpighian Tubules    4359.7 Larval Fat Body    4926.7 Larval Salivary Gland    8435.7 Larval Trachea    4977.8 Larval Carcass    4100.95 Adult Head    2603.1 Adult Eye    1569.075 Adult Brain    1727.6 Adult Thoracic-Abdominal Ganglion    2109.1 Adult Crop    4093.8 Adult Midgut    3151 Adult Hindgut    3481.1 Adult Malpighian Tubules    4079.5 Adult Fat Body    1241.4 Adult Salivary Gland    2372.1 Adult Heart    2356.925 Adult VirginFemale Spermatheca    3220.8 Adult InseminatedFemale Spermatheca    3217.4 Adult Ovary    2887.9 Adult Testis    1885.6 Adult Male Accessory Gland    3478.1 Adult Carcass    2692.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2603.1   NA  Eye    1569.075   NA  Brain    1727.6   1462.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2109.1   NA  Crop    4093.8   1832.6  Midgut    3151   3499.6  Hindgut    3481.1   4359.7  Malpighian Tubules    4079.5   4926.7  Fat Body    1241.4   8435.7  Salivary Gland    2372.1   NA  Heart    2356.925   4977.8  Trachea    NA   NA  VirginFemale Spermatheca    3220.8   NA  InseminatedFemale Spermatheca    3217.4   NA  Ovary    2887.9   NA  Testis    1885.6   NA  Male Accessory Gland    3478.1   4100.95  Carcass    2692.8 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_10
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001149 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10045-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for GstD1 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 GstD1GD6846 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of GstD1 Class Mutagen Stocks Known lesion GstD1d07341 1 -- GstD1G15553 P-element activity 1 -- GstD133f1 0 Yes GstD1d11179 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of GstD1 Class Mutagen Stocks Known lesion GstD1GD6846 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes GstD1KK112645 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes GstD1hs.PA in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes GstD1hs.T:Zzzz\FLAG in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes GstD1Scer\UAS.cPa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Δ33-4 (Pielage et al., 2004) Df(3R)Exel6164 (Ryder, 2004.4.26) Df(3R)Exel6165 (Ryder, 2004.4.26) Df(3R)Exel7314 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data heat-shock construct P{hs-GstD1.D1F-UTR} NA P{hs-GstD1.D1-UTR} NA reporter construct P{GstD1-lacZ.S} No UAS construct P{GD6846} NA P{KK112645} NA characterization construct P{hs-GstD1::GstD2.D1-66-D21} NA P{hs-GstD1::GstD2.D1-171-D21} NA P{hs-GstD1::GstD2.D21-65-D1} NA P{hs-GstD1::GstD2.D21-170-D1} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}GstD1G15553 NA P{EPgy2}EY02348 NA P{XP}GstD1d04829 NA P{XP}GstD1d07341 NA P{XP}GstD1d11179 NA miscellaneous insertions P{UAST-YFP.Rab18.S19N}03 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function
CV term Evidence References
DDT-dehydrochlorinase activity inferred from direct assay (Low et al., 2010) glutathione transferase activity inferred from direct assay (Cochrane and Leblanc, 1986, Sawicki et al., 2003)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
glutathione transferase activity inferred from sequence or structural similarity with UniProtKB:P42860 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1991.2.1)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions GstD1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66612 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001149 DroID - A comprehensive database of gene and protein interactions. • FBgn0001149 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41503
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17052 Dere\GstD1 Dper\GL27184 Dpse\GA10031 Dsec\GstD1 Dsim\GstD1 Dvir\GJ24385 Dwil\GK11204 Dyak\GstD1
Curated drosophilid orthologs	Dari\GstD1 (Matzkin et al., 2006) Dere\GstD1   Dmau\GstD1   Dmoj\GstD1 (Matzkin et al., 2006) Dnav\GstD1 (Matzkin et al., 2006) Dpse\GA10031   Dsec\GstD1   Dsim\GstD1   Dtei\GstD1   Dyak\GstD1
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001061-PA Aedes aegypti (mosquito) AGAP004164-PD Anopheles gambiae (mosquito) XP_392997.3 Apis mellifera (honey bee) XP_001942713.1 Acyrthosiphon pisum (pea aphid) BGIBMGA002222-PA Bombyx mori (silk worm) CPIJ002681 Culex pipens (mosquito) 303282 Daphnia pulex (daphnia) XP_001607855.1 Nasonia vitripennis (wasp) PHUM004872-PA Pediculus humanus (human body louse) XP_974273.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50099 NV15991 NV12288 LH12900 ISCW024224 ISCW011508 FBgn0243209 FBgn0013168 FBgn0216032 FBgn0213887 FBgn0213886 FBgn0213883 FBgn0213884 FBgn0213882 FBgn0213215 FBgn0213214 FBgn0211467 FBgn0211465 FBgn0209960 FBgn0209956 FBgn0012838 FBgn0012785 JGI_V11_303282 JGI_V11_317266 FBgn0070090 FBgn0164765 FBgn0147102 FBgn0145920 FBgn0145082 FBgn0127650 FBgn0120580 FBgn0012266 FBgn0094959 FBgn0094960 FBgn0094071 CPIJ002661 BGIBMGA002222 ACYPI008657 ACYPI008550 ACYPI008042 ACYPI006899 ACYPI006598 ACYPI005620 ACYPI001068 GB18045 GSTD1 GSTD2 AAEL006764 PB24592 PHUM189430 GLEAN_07571
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	26926 y1 w*; P{EP}GstD1G15553
Harvard	- P{XP}GstD1d07341
VDRC	v103246 P{KK112645}VIE-260B v17969 w1118 P{GD6846}v17969
Genomic Clones ( 2 )
	BACR28I14 BACR44K17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 198 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP01777 RH47312
Other clones	DPiM_RH47312 IP20147 yak-em_GstD1
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03448 GH03460 GH07673 GH07784 GH11034 GH16867 GH22301 GH24223 GH24307 GH24442 GH25057 GH25753 GM02020 GM09644 GM09926 GM13444 GM19874 GM22128 GM26288 GM29237 GM32367 LD14723 LP06018 LP06820 LP11533 LP11554 LP12105 LP12138 LP12319 LP15350 LP19951 RE06274 RE07083 RE16346 RE16570 RE19066 RE33216 RE34673 RE44009 RE56727 RE65110 RE65215 RE67818 RE67938 RE69010 RE72944 RH04551 RH05509 RH05968 RH05994 RH08336 RH08355 RH12264 RH22717 RH22974 RH24289 RH26952 RH34382 RH34512 RH34914 RH36566 RH38826 RH40535 RH41868 RH56132 RH58532 RH61202 RH62829 RH63329 RH66495 RH67765 RH70122
Other clones	79679 106888 117758 145599 153491 523409 524044 524767 524916 533973 561884 562200 568889 572729 576495 bs11d05 bs33e08 bs44c11 bs71h01 bs81a08 CK01.118C.G10 CK01.126D.H6 CK01.127C.H6 CK01.129D.H2 CK01.145D.H3 Dmel_dig_000833_0594_2367 Dmel_dig_000838_0631_0292 Dmel_dig_001800_0647_3712 Dmel_dig_004956_0642_1708 Dmel_dig_005799_0706_1649 Dmel_dig_006397_0698_2195 Dmel_dig_006734_0639_0674 Dmel_dig_007488_0643_1673 Dmel_dig_007736_0671_0971 Dmel_dig_010525_0674_1440 Dmel_dig_011013_0686_2442 Dmel_dig_012577_0685_1038 Dmel_dig_013812_0662_3126 Dmel_dig_014315_0717_1215 Dmel_dig_018677_0674_1313 Dmel_dig_019925_0615_3220 Dmel_neb_006600_0628_3613 Dmel_neb_008477_0944_3003 Dmel_neb_009545_0693_2623 Dmel_neb_010581_0884_3527 Dmel_neb_011434_0927_2775 Dmel_neb_014551_0825_0645 Dmel_neb_016310_0833_2051 EC13521 EC22121 EC28193 EC28773 EC29293 EC32717 EC34080 EC40369 EK089957 EK097163 EK097748 EK119830 EK237744 EK256842 EN03851 EN04647 EN05863 EN06152 EN09944 EN13321 EN13912 EN14128 EN16936 EN17761 ESG0114b.B21_F10 ESG0114d.B21_A06 FGC006F02 FGC028A11 FGH110F09 FGM223D02 FGM231D09 FGM307H05 FGM322A01 RH09431 RP003051279 RP003057040 RP003075953 RP003090899 RP003126265 RP003139979 RP003144223 RP003145212 RP003243932 RP003245705 RP003281703 RP003288231 RP003288878 RP003292939 RP003306150 RP003307054 RP003320863 RP003322197 RP003343506 RP003417068 RP003422837 RP003431264 RP003473151 RP003483460 RP003497114 RP003500011 RP003500708 RP003505902 RP003517307 RP003518725 RP003535494 RP003577525 RP003611431 RP003634776 RP003657180 RP003659616 RP003661474 RP003669852 UUGC0513
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0001149 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41503
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Quantifying rates of protein sequence divergence within and between species reveals that the Drosophila genome harbors a substantial proportion of genes with a very high divergence rate. (Schmid and Tautz, 1997) mRNA levels for GST do not increase at adult day 5 in strain showing extended longevity phenotype (ELP). (Dudas and Arking, 1995) Glutathione S transferase activity has been analysed in various developmental stages. (Hunaiti et al., 1995) Pentobarbital rapidly induces the expression of GstD1, by activating transcription. (Tang and Tu, 1995) Dehydro-chlorinase activity of the protein is determined by biochemical analysis using gas-liquid chromatography to assess the contribution of the isozymes to the DDT-resistant phenotype. (Tang and Tu, 1994) Encodes glutathione S transferase subunit 1 (Toung et al., Biochem. biophys. Res. Commun. 178: 1205--1211, Toung and Tu, Biochem. biophys. Res. Commun. 182: 355--360). (Toung et al., 1993) GstD1 locus is flanked by two clusters of heat shock genes. Enzyme activity in Kco cells is elevated slightly to two fold under heat shock. (Toung et al., 1991) The GstD1 gene function has been implicated in repairing cellular damage inflicted by oxygen free radicals. (Lloyd et al., 1990) Glutathione S-transferase enzyme has been purified and characterised. (Cochrane et al., 1987) Glutathione S-transferase activity shows differences in age dependence, substrate selectivity and subcellular location in adult Drosophila, suggesting the presence of multiple forms of the enzyme. Differences in activity between different Drosophila strains are also seen. (Ottea et al., 1987) Substrate specificities and pH optima suggest that GstD1 enzyme has a restricted range of substrates. Pentamethyl benzene (PMB) causes a 50% increase in enzyme activity, whereas β,naphthoflavone and phenobarbital have no effect. The degree of response to PMB is modulated by other genes on chromosome 2. Response of enzyme activity to 1-chloro-2,3-dinitrobenzene (CDNB) and ethacrynic acid (EA) can also differ. (Cochrane and Leblanc, 1986) GstD1 gene product does not conjugate the epoxides styrene-7,8-oxide and 1,2-epoxy-3-propane. (Jansen et al., 1984) Glutathione S-transferase activity has been investigated in sub-cellular fractions of D.melanogaster. (Baars et al., 1979)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079602 NM_001038953 RefSeq (Proteins) • NP_524326 NP_001034042 DDBJ / EMBL / GenBank • AA803543 AAA04220 AAF54786 AAF54786.1 AAM52032 ABC66168 AI108593 AI945315 AI946965 AY121705 BI617087 CAA32449 M97702 S51044 X14233 Entrez Gene - A searchable database of RefSeq genes. • 41503 UniProtKB/Swiss-Prot • P20432
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, N-terminal (IPR004045) Glutathione S-transferase, C-terminal (IPR004046) Glutathione S-transferase, C-terminal-like (IPR010987) Thioredoxin-like fold (IPR012336) Glutathione S-transferase/chloride channel, C-terminal (IPR017933)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66612 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0001149 DroID - A comprehensive database of gene and protein interactions. • FBgn0001149 DRSC - Results from RNAi screens. • FBgn0001149 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0001149 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10045-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0001149 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41503 InParanoid A subset of ortholog calls from InParanoid. • AAEL001061-PA Aedes aegypti (mosquito) AGAP004164-PD Anopheles gambiae (mosquito) XP_392997.3 Apis mellifera (honey bee) XP_001942713.1 Acyrthosiphon pisum (pea aphid) BGIBMGA002222-PA Bombyx mori (silk worm) CPIJ002681 Culex pipens (mosquito) 303282 Daphnia pulex (daphnia) XP_001607855.1 Nasonia vitripennis (wasp) PHUM004872-PA Pediculus humanus (human body louse) XP_974273.1 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41503 modMine - Data generated by the modENCODE project. • FBgn0001149 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50099 NV15991 NV12288 LH12900 ISCW024224 ISCW011508 FBgn0243209 FBgn0013168 FBgn0216032 FBgn0213887 FBgn0213886 FBgn0213883 FBgn0213884 FBgn0213882 FBgn0213215 FBgn0213214 FBgn0211467 FBgn0211465 FBgn0209960 FBgn0209956 FBgn0012838 FBgn0012785 JGI_V11_303282 JGI_V11_317266 FBgn0070090 FBgn0164765 FBgn0147102 FBgn0145920 FBgn0145082 FBgn0127650 FBgn0120580 FBgn0012266 FBgn0094959 FBgn0094960 FBgn0094071 CPIJ002661 BGIBMGA002222 ACYPI008657 ACYPI008550 ACYPI008042 ACYPI006899 ACYPI006598 ACYPI005620 ACYPI001068 GB18045 GSTD1 GSTD2 AAEL006764 PB24592 PHUM189430 GLEAN_07571
Synonyms & Secondary IDs ( 33 )
Reported As
Symbol Synonym	CG10045 (Vierstraete et al., 2004, Sun et al., 2010, Keleman et al., 2009.8.5, Marco et al., 2004, Ling and Salvaterra, 2011, Alias and Clark, 2007, Cammarato et al., 2011) D1 (Alias and Clark, 2007) DmGST1 (Ranson et al., 2001, Lougarre et al., 1999, Toung et al., 1993, Morton, 1993, Murray et al., 1993) DmGST-1 (Chelvanayagam et al., 2001, Beall et al., 1992) DmGst1 (Toung et al., 1991) DmGSTD1 (Sawicki et al., 2003, Chelvanayagam et al., 2001, Zimniak and Benes, 2002.7.15, Low et al., 2010) dmGSTD1 (Low et al., 2010) DmGSTD1-1 (Sharma et al., 2004, Singh et al., 2002, Sawicki et al., 2002) Gst (Ranz et al., 2001, Ranz et al., 2001, Lloyd et al., 1990, Faridwajidi, 1993, Faridwajidi and Jowett, 1993, ) GST (Arking, 1998, Arking et al., 1996, Harshman et al., 1991, Ottea et al., 1987) G-S-T (Tautz and Schmid, 1998) GST-1 (Pielage et al., 2004, Agianian et al., 2003, Singh et al., 2002, Clayton et al., 1998) GST1 (Le Goff et al., 2001) Gst1 (Toung et al., 1991) Gst1-1 (Schmid and Tautz, 1997) GST1-1 (Pearson, 1996, Toung et al., 1990) GSt1-1 (Akaboshi et al., 1994) Gst1.1   GSTase (Cochrane et al., 1987) gstD (Tuxworth et al., 2011) GSTD1 (Wang et al., 2003, Zou et al., 2000, Low et al., 2008, Low et al., 2007, Hooven et al., 2009, Li et al., 2008, Low et al., 2010, Alias and Clark, 2007) gstD1 (Akgul and Tu, 2002, Tang and Tu, 1995, Tang and Tu, 1994, Toung et al., 1993, Karpac et al., 2009, Sykiotis and Bohmann, 2008, Sharma et al., 2011) GstD1 (Sun et al., 2010, Zhang et al., 2007, Allen and Spradling, 2008, Gilchrist et al., 2008, Morozova et al., 2006, Anholt and Williams, 2010, Ling and Salvaterra, 2011, Boyd et al., 2011) Gst-D1 (Nakamura et al., 1999) gst-D1-1 (Singh et al., 2000) T5 (Vierstraete et al., 2004) unnamed (Hunaiti et al., 1995)
Name Synonym	CG10045 Glutathione S-transferase (Kang et al., 2002) Glutathione S-transferase 1 (Pearson, 1998) Glutathione-S-transferase 1 (Ling and Salvaterra, 2011) Glutathione S transferase D1 (Cammarato et al., 2011) Glutathione S-transferase-D1 (Nakamura et al., 1999) glutathione S-transferase D1 (Boyd et al., 2011)
Secondary FlyBase IDs
	FBgn0010045
References ( 99 )
Generate a list of	All references relating to this gene ( 99 )
List References by type	Research paper  ( 65 ) Supplementary material  ( 6 ) Review  ( 4 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 9 ) FlyBase analysis  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 3 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 7 )
	Boyd et al., 2011, Free Radical Biol. Med. 50(11): 1669--1678 Nectarine promotes longevity in Drosophila melanogaster. [FBrf0213612] Ling and Salvaterra, 2011, PLoS ONE 6(3): e17762 Robust RT-qPCR Data Normalization: Validation and Selection of Internal Reference Genes during Post-Experimental Data Analysis. [FBrf0213272] Sharma et al., 2011, Chemosphere 82(3): 370--376 Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. [FBrf0212610] Tuxworth et al., 2011, Hum. Mol. Genet. 20(10): 2037--2047 The Batten disease gene CLN3 is required for the response to oxidative stress. [FBrf0213533] Anholt and Williams, 2010, Chem. Senses 35(1): 21--30 The soluble proteome of the Drosophila antenna. [FBrf0209552] Low et al., 2010, J. Mol. Biol. 399(3): 358--366 Recognition and Detoxification of the Insecticide DDT by Drosophila melanogaster Glutathione S-Transferase D1. [FBrf0211172] Sun et al., 2010, Exp. Gerontol. 45(3): 243--251 Açai palm fruit (Euterpe oleracea Mart.) pulp improves survival of flies on a high fat diet. [FBrf0210041] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...