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Gene Dmel\Hsc70-4

General Information
Symbol	Dmel\Hsc70-4	Species	D. melanogaster
Name	Heat shock protein cognate 4	Annotation symbol	CG4264
Feature type	protein_coding_gene	FlyBase ID	FBgn0001219
Gene Model Status	Current	Stock availability	22 publicly available
Also Known As	HSC4, Hsc70, BAP74, hsp70
Genomic Location
Chromosome (arm)	3R	Recombination map	3-56.5
Cytogenetic map	88E4-88E4	Sequence location	3R:11,068,409..11,072,336 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Heat shock protein cognate 4 is referred to in FlyBase by the symbol Dmel\Hsc70-4 (CG4264, FBgn0001219). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: chaperone binding. There is experimental evidence that it is involved in the biological process: RNA interference; axon guidance; neurotransmitter secretion; embryonic development via the syncytial blastoderm; nervous system development; axonal fasciculation; vesicle-mediated transport. 52 alleles are reported. The phenotypes of these alleles are annotated with: organ system; multicellular structure; organ system subdivision; adult segment; imaginal precursor; cytoplasmic part; external compound sense organ; adult; larval head segment; organelle. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630637_s_at completely aligns to an exonic region common to each of the 6 FlyBase-annotated transcript isoforms of Hsc70-4. Gene sequence location is 3R:11068409..11072336.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02	Controlled Vocabulary Terms mitochondrial inner membrane cytoplasm perichromatin fibrils
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88E4-88E4   Limits computationally determined from genome sequence between P{EP}CG33967EP666 and P{lacW}Hsc70-4L3929
Experimentally Determined Cytological Location
Cytogenetic map Notes References 88E8-88E9   (determined by in situ hybridisation)   (Spradling et al., 1999) 88E8-88E9   (determined by in situ hybridisation)   (Perrimon et al., 1996) 88E3-88E4     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	3-56.5 (Hing et al., 1999)
Left of (cM)	Sb (Hing et al., 1999, Mollaaghababa et al., 2001) sr (Mollaaghababa et al., 2001)
Right of (cM)	red (Hing et al., 1999) cu (Mollaaghababa et al., 2001)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Hsc70-4 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 Annotated transcripts do not represent all supported alternative splices within 5' UTR. Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Hsc70-4-RA FBtr0083057  NM_079632   2368   651 Hsc70-4-RB FBtr0083060  NM_169625   2339   651 Hsc70-4-RC FBtr0083058  NM_169626   2280   651 Hsc70-4-RD FBtr0083059  NM_169627   2352   651 Hsc70-4-RE FBtr0083055  NM_176502   2284   651 Hsc70-4-RF FBtr0083056  NM_176503   2359   651 Hsc70-4-RG FBtr0337053  NM_001275657   2336   651
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Hsc70-4-PA   FBpp0082516   71.1   651   5.16     NP_524356   AAF55150 Hsc70-4-PB   FBpp0082519   71.1   651   5.16     NP_731987   AAN13637 Hsc70-4-PC   FBpp0082517   71.1   651   5.16     NP_731988   AAN13638 Hsc70-4-PD   FBpp0082518   71.1   651   5.16     NP_731989   AAN13639 Hsc70-4-PE   FBpp0082514   71.1   651   5.16     NP_788679   AAO41567 Hsc70-4-PF   FBpp0082515   71.1   651   5.16     NP_788680   AAO41568 Hsc70-4-PG   FBpp0307982   71.1   651   5.16     NP_001262586   AGB95967
Additional Polypeptide Data & Comments
Reported size (kDa)	70 (kD) (Carbajal et al., 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Heat shock protein 70, conserved site (IPR018181) Heat shock protein 70 family (IPR013126) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME04264
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201336   AA201373   AA201397   AA202015   AA202118   AA202137   AA202169   AA202233   AA202240   AA202335   AA202351   AA202376   AA202514   AA202533   AA202548   AA202614   AA202770   AA202836   AA202876   AA203073   AA246360   AA246525   AA247017   AA247085   AA263245   AA263303   AA263410   AA263728   AA263745   AA263756   AA263770   AA264004   AA264135   AA264327   AA264386   AA264582   AA264606   AA264691   AA264806   AA390511   AA390637   AA390766   AA390907   AA390919   AA391000   AA391044   AA391121   AA391157   AA391235   AA391438   AA391463   AA391722   AA392397   AA392610   AA392680   AA392694   AA392825   AA392939   AA392949   AA392974   AA393002   AA438278   AA438465   AA438531   AA438828   AA439095   AA439221   AA439324   AA439459   AA440045   AA440051   AA440090   AA440152   AA440198   AA440445   AA440566   AA440613   AA440926   AA440993   AA441146   AA441332   AA441365   AA441480   AA441657   AA536327   AA538759   AA538761   AA538899   AA539004   AA539006   AA539114   AA539206   AA539482   AA539573   AA539650   AA539874   AA540054   AA540128   AA540170   AA540314   AA540349   AA540575   AA540785   AA540813   AA540981   AA541048   AA567231   AA567239   AA567266   AA694889   AA694927   AA695163   AA695205   AA695208   AA695251   AA695382   AA695515   AA695660   AA695702   AA695813   AA695949   AA696000   AA696007   AA696009   AA696095   AA696332   AA696401   AA696402   AA696570   AA696572   AA696573   AA696918   AA697157   AA697245   AA697677   AA697862   AA698080   AA698646   AA698962   AA699281   AA735114   AA735413   AA735417   AA735473   AA735486   AA735773   AA736020   AA736131   AA801648   AA801693   AA801840   AA801870   AA801878   AA802031   AA802205   AA802353   AA802411   AA802450   AA802539   AA802540   AA802640   AA802708   AA802969   AA802996   AA803052   AA803090   AA803167   AA803342   AA803536   AA803663   AA803745   AA803796   AA803822   AA803897   AA804016   AA804049   AA816401   AA816420   AA816820   AA817008   AA817042   AA817051   AA817072   AA817138   AA817236   AA817305   AA817346   AA817434   AA817506   AA817650   AA820246   AA820270   AA820280   AA820366   AA820511   AA820659   AA820732   AA820834   AA820866   AA820877   AA820994   AA821125   AA821132   AA940601   AA940749   AA940788   AA940938   AA941045   AA941130   AA941148   AA941269   AA941333   AA941354   AA941393   AA941405   AA941434   AA941501   AA941703   AA941833   AA941926   AA941987   AA942110   AA942420   AA942451   AA942637   AA948842   AA949085   AA949095   AA949134   AA949226   AA949583   AA949659   AA949674   AA949695   AA949752   AA949849   AA949891   AA949906   AA949960   AA950185   AA950282   AA950365   AA950374   AA950410   AA950430   AA950447   AA950492   AA950533   AA950538   AA950540   AA950691   AA950939   AA950954   AA951120   AA951144   AA951169   AA951215   AA951245   AA951362   AA951552   AA951557   AA951588   AA951595   AA951663   AA951733   AA951783   AA951836   AA951840   AA951934   AA952018   AA952121   AA952181   AA952251   AA952288   AA952300   AA978538   AA978563   AA978734   AA978934   AA979095   AA979306   AA979352   AA979364   AA990642   AA990745   AA990871   AE014297 AAF55150   AE014297 AAN13637   AE014297 AAN13638   AE014297 AAN13639   AE014297 AAO41567   AE014297 AAO41568   AE014297 AGB95967   AI061710   AI061798   AI062047   AI062098   AI062320   AI062355   AI062803   AI062928   AI062958   AI062969   AI062983   AI063231   AI063342   AI063382   AI063661   AI064002   AI064004   AI064118   AI106835   AI107007   AI107285   AI107741   AI107821   AI108043   AI108317   AI108478   AI108491   AI108581   AI108922   AI109227   AI109335   AI109368   AI109441   AI109530   AI109747   AI109910   AI109948   AI110187   AI113835   AI114417   AI133870   AI134224   AI134730   AI134870   AI135302   AI135547   AI135593   AI135875   AI135936   AI135945   AI135983   AI238020   AI238077   AI238527   AI238721   AI238812   AI238857   AI238873   AI239192   AI239193   AI256963   AI257358   AI257465   AI257601   AI257672   AI257973   AI258214   AI258380   AI258687   AI258832   AI259017   AI259137   AI259505   AI259578   AI260044   AI260113   AI260366   AI260541   AI260771   AI261007   AI292408   AI292412   AI292517   AI292599   AI292636   AI292649   AI292715   AI292959   AI293479   AI293870   AI293997   AI294469   AI294605   AI294862   AI294938   AI294956   AI294963   AI295001   AI295293   AI295332   AI295640   AI295801   AI295880   AI295948   AI296072   AI296350   AI296451   AI297142   AI297193   AI386597   AI386908   AI386926   AI387003   AI387020   AI387154   AI387295   AI387374   AI387620   AI387698   AI387728   AI387780   AI387856   AI388261   AI388280   AI388538   AI388629   AI389179   AI389718   AI389728   AI389735   AI402353   AI402369   AI402452   AI402510   AI402668   AI402968   AI403024   AI403155   AI403984   AI404233   AI404408   AI404480   AI404940   AI406125   AI406136   AI406157   AI406254   AI455582   AI455583   AI455620   AI455663   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BI354040   BI354163   BI354621   BI354645   BI354688   BI354886   BI354919   BI355015   BI355021   BI355059   BI355131   BI355148   BI355236   BI355403   BI355422   BI355429   BI355482   BI355536   BI355539   BI355632   BI355694   BI356191   BI356396   BI356640   BI357440   BI357952   BI358436   BI358509   BI361290   BI361435   BI361486   BI361490   BI361517   BI361831   BI362058   BI362556   BI362976   BI363457   BI363591   BI363925   BI364307   BI364416   BI364555   BI365249   BI365386   BI365482   BI366009   BI366073   BI366447   BI366779   BI366945   BI366955   BI367312   BI367482   BI367822   BI367931   BI368142   BI368636   BI368733   BI368820   BI369308   BI369458   BI369520   BI369640   BI370015   BI370340   BI370478   BI370624   BI370771   BI370802   BI370936   BI370978   BI370993   BI371079   BI371222   BI371224   BI371840   BI371894   BI372927   BI373347   BI373540   BI374220   BI374460   BI374553   BI374851   BI374892   BI374998   BI375265   BI376121   BI481742   BI481805   BI482262   BI482298   BI482630   BI483007   BI483432   BI483444   BI483648   BI483730   BI483828   BI484458   BI484904   BI484953   BI485715   BI486033   BI486140   BI486369   BI487146   BI487214   BI567011   BI570551   BI571856   BI571859   BI573579   BI573580   BI575896   BI577350   BI577372   BI577395   BI577986   BI579719   BI580150   BI580411   BI580685   BI580811   BI580910   BI580931   BI583546   BI586857   BI590759   BI591093   BI606368   BI613557   BI613961   BI616826   BI618263   BI619343   BI620246   BI624173   BI625302   BI626511   BI627002   BI629367   BI631203   BI632283   BI632409   BI632524   BI632552   BI632762   BI632903   BI633384   BI633392   BI633538   BI633671   BI633746   BI634753   BI634969   BI635323   BI635512   BI636073   BI636237   BI636458   BI636599   BI636677   BI636808   BI636869   BI636995   BI637387   BI637716   BI638228   BI638449   BI638533   BI638938   BI638980   BI638997   BI639122   BI639360   BI639416   BI639488   BI639515   BI639545   BI639598   BI639785   BI639946   BI640445   BI640536   BI640597   BI640672   BI640725   BI641149   BI641295   BI641743   BP540715   BP540751   BP547761   BP548880   BP549210   BP549951   BP549952   BP550834   BP551369   BP551370   BP553062   BP553063   BP553253   BP553254   BP553861   BP553862   BP555201   BP556943   BQ102807   BQ102862   BQ102984   BQ103096   BQ103286   BQ103426   BQ103454   BQ103457   BQ103462   BQ103512   BQ103513   BQ103514   BQ103561   BQ103600   BQ103667   BQ103718   BQ103722   BT023894   BT099625   BX017948   BX025233   BX029450   BX040750   BX043081   BX044695   BX054336   BX055687   BX064835   CA807844   CK131665   CK131764   CK132109   CK132260   CK132469   CK134889   CK134896   CK605013   CK605014   CK657045   CK657698   CK657943   CK658146   CK658183   CK658195   CK658423   CK658720   CK658879   CK658916   CK658961   CK659529   CK659926   CK660267   CK660371   CK660405   CK660461   CK660676   CK661094   CK661234   CK661369   CK661489   CK661506   CK661520   CK661721   CK661788   CK661899   CK662242   CK662301   CK662461   CO152955   CO153194   CO153458   CO153794   CO154090   CO154296   CO154352   CO154431   CO154442   CO154617   CO155074   CO155085   CO155157   CO155324   CO155465   CO155537   CO155797   CO156175   CO156340   CO178979   CO179306   CO180172   CO180341   CO196643   CO262249   CO262259   CO264971   CO269428   CO271962   CO275652   CO279352   CO281008   CO281407   CO285243   CO286889   CO288392   CO288866   CO289621   CO290137   CO291516   CO294690   CO296490   CO297508   CO297902   CO297926   CO299814   CO307771   CO307945   CO311607   CO312413   CO313381   CO313631   CO313716   CO318105   CO320959   CO321226   CO323558   CO323717   CO324000   CO325676   CO327186   CO329563   CO330739   CO335440   CO335492   CO337011   CO337142   CR937294   CR937348   CZ472772   CZ476878   CZ483607   CZ483608   CZ490040   DQ440299   DQ675540   EC052867   EC053605   EC058672   EC059287   EC062363   EC063248   EC066144   EC067538   EC069064   EC069066   EC070282   EC070518   EC075020   EC076890   EC077185   EC077873   EC078204   EC078838   EC081224   EC081689   EC081888   EC081896   EC083408   EC085314   EC085351   EC086225   EC087133   EC088080   EC089052   EC195528   EC196665   EC196682   EC197675   EC198282   EC198789   EC199197   EC199448   EC201388   EC201726   EC202718   EC205460   EC205726   EC205960   EC207951   EC208678   EC210420   EC212327   EC218653   EC219383   EC219623   EC221792   EC223629   EC223948   EC223973   EC224268   EC225132   EC225707   EC227720   EC229972   EC230470   EC230584   EC230659   EC233362   EC233789   EC234435   EC235242   EC235305   EC236503   EC238049   EC240298   EC243948   EC245018   EC245788   EC246657   EC247307   EC248188   EC248929   EC249559   EC257701   EC258359   EC261329   EC261778   EC261832   EC261905   EC262220   EC262773   EC262913   EC262970   EC263592   EC263780   EC264688   EC264765   EC265146   EC265645   EC265653   EC265681   EC265776   EC265780   EC266014   EC266451   EC266471   EC266539   EC266956   EC267288   EC267382   EL870015   EL870021   EL872585   EL872708   EL875293   EL875294   EL876710   EL883099   EL883221   EL883222   EL883339   EL884139   EL884272   EL884273   EV575073   EV575100   EV575900   EV576208   EV577176   EV577371   EV580074   EV580096   EV581017   EV581636   EV582734   EV583381   EV583413   EV583947   EV584418   EV584689   EV585213   EV585330   EV585535   EV585657   EV586243   EV586481   EV586631   EV586919   EV586955   EV587764   EV588337   EV588701   EV589165   EV589389   EV589798   EV590475   EV590992   EV592025   EV593390   EV593632   EV593819   EV594448   EV595749   EV595763   EV596527   EV596598   EV596854   EV597189   EV597521   EV598783   EV599367   EV599447   EV599647   EV600418   GH747682   GH747788   GH748473   GH749004   GH749399   GH751513   GH751574   GH752077   GH752209   GH753046   GH755033   GH756871   GH759562   GH759564   GH760481   GH760758   GH761341   GH770652   GH770913   GH771276   GH772835   GH774517   GH774574   GH776582   GH776795   GH778171   GH780965   GH781454   GH782454   GH783433   GH784363   GH785656   GH788354   GH788999   GH790500   GH793034   GH794358   GH794421   GH794667   GH796057   GH796764   GH796799   GH797597   GH800635   GH800840   GH801855   GH802874   GH804270   GH805414   GH805625   GH806107   GH807146   GH808070   GH809231   GH811789   GH811855   GH812001   GH812033   GH812890   GH813510   GH814172   GH818426   GH819642   GH819743   GH819791   GH819986   GH820031   GH820844   GH821528   GH822729   GH822829   GH823094   GH825871   GH827132   GH827146   GH828240   GH828272   GH828706   GH829624   GH830630   GH831720   GH832096   GH835302   GH835478   GH835687   GH836388   GH839540   GH839701   GH839997   GH840194   GH841532   GH841816   GH842250   GH844073   GH844202   GH844952   GH846435   GH848239   GH848443   GH849776   GH850906   GH850980   GH851365   GH852462   GH853776   GH854569   GH854774   GH855827   GH856509   GH857540   GH858561   GH858926   GH859581   GH860179   GH860798   GH861121   GH861542   GH862084   GH862495   GH863325   GH864407   GH865210   GH865256   GH867660   GH867690   GH867713   GH868531   GH869512   GH869535   GH870480   GH871764   GH871974   GH872603   GH872772   GH874626   GH875066   GH876383   GH876963   GH877340   GH878306   GH878887   GH882269   GH884072   GH885129   GH885173   GH886960   GH887152   GH887718   GH889136   GH890663   GH891825   GH891909   GH892144   GH892421   GH892646   GH893475   GH896152   GH896616   GH896650   GH897155   GH897173   GH897479   GH897573   GH898510   GH898681   GH898723   GH899355   GH900448   GH901068   GH901110   GH904318   GH906883   GH909024   GH911614   GH911960   GH912637   GH914286   GH914887   GH918626   GH919383   GH920161   GH920517   GH921132   GH923024   GH923397   GH924929   GH926481   GH929816   GH933157   GH934513   GH938100   GH939397   GH940484   HQ384021   J02569 AAA28631   L01500 AAB59186   M36113   M36114 AAA28627
UniProtKB/Swiss-Prot	P11147
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Bronk et al., 2001) third instar larval stage   embryonic/larval neuromuscular junction   • terminal bouton (Bronk et al., 2001) mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
	Hsc70-4 protein is expressed in all cells throughout embryonic development. (Carbajal et al., 1993, Bronk et al., 2001)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) cytoplasm inferred from direct assay (Carbajal et al., 1993) lipid particle inferred from direct assay (Beller et al., 2006, Beller et al., 2006, Cermelli et al., 2006) microtubule associated complex inferred from direct assay (Hughes et al., 2008) colocalizes_with mitochondrial inner membrane inferred from direct assay (Carbajal et al., 1993) nucleus inferred from direct assay (Carbajal et al., 1993) perichromatin fibrils inferred from direct assay (Carbajal et al., 1993) precatalytic spliceosome inferred from direct assay (Herold et al., 2009) colocalizes_with Z disc inferred from direct assay (Arndt et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    3138.3 Larval Midgut    5477.5 Larval Hindgut    4977.8 Larval Malpighian Tubules    5331.1 Larval Fat Body    5394.6 Larval Salivary Gland    6582.7 Larval Trachea    6032.625 Larval Carcass    5346.275 Adult Head    3873.1 Adult Eye    4610.925 Adult Brain    2491.2 Adult Thoracic-Abdominal Ganglion    2759.3 Adult Crop    6556.6 Adult Midgut    4268.2 Adult Hindgut    5077.8 Adult Malpighian Tubules    4832.3 Adult Fat Body    5674.5 Adult Salivary Gland    4515.7 Adult Heart    5984 Adult VirginFemale Spermatheca    4692 Adult InseminatedFemale Spermatheca    4930.6 Adult Ovary    3604.6 Adult Testis    2363 Adult Male Accessory Gland    6037.7 Adult Carcass    5047.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (3138.3) Larval Midgut  (5477.5) Larval Hindgut  (4977.8) Larval Malpighian Tubules  (5331.1) Larval Fat Body  (5394.6) Larval Salivary Gland  (6582.7) Larval Trachea  (6032.625) Larval Carcass  (5346.275) Adult Head  (3873.1) Adult Eye  (4610.925) Adult Brain  (2491.2) Adult Thoracic-Abdominal Ganglion  (2759.3) Adult Crop  (6556.6) Adult Midgut  (4268.2) Adult Hindgut  (5077.8) Adult Malpighian Tubules  (4832.3) Adult Fat Body  (5674.5) Adult Salivary Gland  (4515.7) Adult Heart  (5984) Adult VirginFemale Spermatheca  (4692) Adult InseminatedFemale Spermatheca  (4930.6) Adult Ovary  (3604.6) Adult Testis  (2363) Adult Male Accessory Gland  (6037.7) Adult Carcass  (5047.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (3138.3) Larval Midgut  (5477.5) Larval Hindgut  (4977.8) Larval Malpighian Tubules  (5331.1) Larval Fat Body  (5394.6) Larval Salivary Gland  (6582.7) Larval Trachea  (6032.625) Larval Carcass  (5346.275) Adult Head  (3873.1) Adult Eye  (4610.925) Adult Brain  (2491.2) Adult Thoracic-Abdominal Ganglion  (2759.3) Adult Crop  (6556.6) Adult Midgut  (4268.2) Adult Hindgut  (5077.8) Adult Malpighian Tubules  (4832.3) Adult Fat Body  (5674.5) Adult Salivary Gland  (4515.7) Adult Heart  (5984) Adult VirginFemale Spermatheca  (4692) Adult InseminatedFemale Spermatheca  (4930.6) Adult Ovary  (3604.6) Adult Testis  (2363) Adult Male Accessory Gland  (6037.7) Adult Carcass  (5047.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3138.3 Larval Midgut    5477.5 Larval Hindgut    4977.8 Larval Malpighian Tubules    5331.1 Larval Fat Body    5394.6 Larval Salivary Gland    6582.7 Larval Trachea    6032.625 Larval Carcass    5346.275 Adult Head    3873.1 Adult Eye    4610.925 Adult Brain    2491.2 Adult Thoracic-Abdominal Ganglion    2759.3 Adult Crop    6556.6 Adult Midgut    4268.2 Adult Hindgut    5077.8 Adult Malpighian Tubules    4832.3 Adult Fat Body    5674.5 Adult Salivary Gland    4515.7 Adult Heart    5984 Adult VirginFemale Spermatheca    4692 Adult InseminatedFemale Spermatheca    4930.6 Adult Ovary    3604.6 Adult Testis    2363 Adult Male Accessory Gland    6037.7 Adult Carcass    5047.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    3138.3 Larval Midgut    5477.5 Larval Hindgut    4977.8 Larval Malpighian Tubules    5331.1 Larval Fat Body    5394.6 Larval Salivary Gland    6582.7 Larval Trachea    6032.625 Larval Carcass    5346.275 Adult Head    3873.1 Adult Eye    4610.925 Adult Brain    2491.2 Adult Thoracic-Abdominal Ganglion    2759.3 Adult Crop    6556.6 Adult Midgut    4268.2 Adult Hindgut    5077.8 Adult Malpighian Tubules    4832.3 Adult Fat Body    5674.5 Adult Salivary Gland    4515.7 Adult Heart    5984 Adult VirginFemale Spermatheca    4692 Adult InseminatedFemale Spermatheca    4930.6 Adult Ovary    3604.6 Adult Testis    2363 Adult Male Accessory Gland    6037.7 Adult Carcass    5047.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (3138.3) Larval Midgut  (5477.5) Larval Hindgut  (4977.8) Larval Malpighian Tubules  (5331.1) Larval Fat Body  (5394.6) Larval Salivary Gland  (6582.7) Larval Trachea  (6032.625) Larval Carcass  (5346.275) Adult Head  (3873.1) Adult Eye  (4610.925) Adult Brain  (2491.2) Adult Thoracic-Abdominal Ganglion  (2759.3) Adult Crop  (6556.6) Adult Midgut  (4268.2) Adult Hindgut  (5077.8) Adult Malpighian Tubules  (4832.3) Adult Fat Body  (5674.5) Adult Salivary Gland  (4515.7) Adult Heart  (5984) Adult VirginFemale Spermatheca  (4692) Adult InseminatedFemale Spermatheca  (4930.6) Adult Ovary  (3604.6) Adult Testis  (2363) Adult Male Accessory Gland  (6037.7) Adult Carcass  (5047.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (3138.3) Larval Midgut  (5477.5) Larval Hindgut  (4977.8) Larval Malpighian Tubules  (5331.1) Larval Fat Body  (5394.6) Larval Salivary Gland  (6582.7) Larval Trachea  (6032.625) Larval Carcass  (5346.275) Adult Head  (3873.1) Adult Eye  (4610.925) Adult Brain  (2491.2) Adult Thoracic-Abdominal Ganglion  (2759.3) Adult Crop  (6556.6) Adult Midgut  (4268.2) Adult Hindgut  (5077.8) Adult Malpighian Tubules  (4832.3) Adult Fat Body  (5674.5) Adult Salivary Gland  (4515.7) Adult Heart  (5984) Adult VirginFemale Spermatheca  (4692) Adult InseminatedFemale Spermatheca  (4930.6) Adult Ovary  (3604.6) Adult Testis  (2363) Adult Male Accessory Gland  (6037.7) Adult Carcass  (5047.9) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3138.3 Larval Midgut    5477.5 Larval Hindgut    4977.8 Larval Malpighian Tubules    5331.1 Larval Fat Body    5394.6 Larval Salivary Gland    6582.7 Larval Trachea    6032.625 Larval Carcass    5346.275 Adult Head    3873.1 Adult Eye    4610.925 Adult Brain    2491.2 Adult Thoracic-Abdominal Ganglion    2759.3 Adult Crop    6556.6 Adult Midgut    4268.2 Adult Hindgut    5077.8 Adult Malpighian Tubules    4832.3 Adult Fat Body    5674.5 Adult Salivary Gland    4515.7 Adult Heart    5984 Adult VirginFemale Spermatheca    4692 Adult InseminatedFemale Spermatheca    4930.6 Adult Ovary    3604.6 Adult Testis    2363 Adult Male Accessory Gland    6037.7 Adult Carcass    5047.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    3873.1   NA  Eye    4610.925   NA  Brain    2491.2   3138.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2759.3   NA  Crop    6556.6   5477.5  Midgut    4268.2   4977.8  Hindgut    5077.8   5331.1  Malpighian Tubules    4832.3   5394.6  Fat Body    5674.5   6582.7  Salivary Gland    4515.7   NA  Heart    5984   6032.625  Trachea    NA   NA  VirginFemale Spermatheca    4692   NA  InseminatedFemale Spermatheca    4930.6   NA  Ovary    3604.6   NA  Testis    2363   NA  Male Accessory Gland    6037.7   5346.275  Carcass    5047.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2206 central nervous system, larvae L3    2063 central nervous system, pupae P8    819 head, virgin 1-day female    842 head, virgin 4-day female    1118 head, virgin 20-day female    1066 head, mated 1-day female    755 head, mated 4-day female    1126 head, mated 20-day female    878 head, mated 1-day male    954 head, mated 4-day male    1202 head, mated 20-day male    1296 salivary gland, larvae L3 wandering    127 salivary gland, white prepupae    848 digestive system, larvae L3 wandering    1742 digestive system, 1-day adult    1244 digestive system, 4-day adult    1506 digestive system, 20-day adult    1717 fat body, larvae L3 wandering    687 fat body, white prepupae    1014 fat body, pupae P8    932 carcass, larvae L3 wandering    2218 carcass, 1-day adult    844 carcass, 4-day adult    1506 carcass, 20-day adult    1595 ovary, virgin 4-day female    2180 ovary, mated 4-day female    2435 testis, mated 4-day male    990 accessory gland, mated 4-day male    768 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (2206) central nervous system, larvae L3  (2063) central nervous system, pupae P8  (819) head, virgin 1-day female  (842) head, virgin 4-day female  (1118) head, virgin 20-day female  (1066) head, mated 1-day female  (755) head, mated 4-day female  (1126) head, mated 20-day female  (878) head, mated 1-day male  (954) head, mated 4-day male  (1202) head, mated 20-day male  (1296) salivary gland, larvae L3 wandering  (127) salivary gland, white prepupae  (848) digestive system, larvae L3 wandering  (1742) digestive system, 1-day adult  (1244) digestive system, 4-day adult  (1506) digestive system, 20-day adult  (1717) fat body, larvae L3 wandering  (687) fat body, white prepupae  (1014) fat body, pupae P8  (932) carcass, larvae L3 wandering  (2218) carcass, 1-day adult  (844) carcass, 4-day adult  (1506) carcass, 20-day adult  (1595) ovary, virgin 4-day female  (2180) ovary, mated 4-day female  (2435) testis, mated 4-day male  (990) accessory gland, mated 4-day male  (768) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (2206) central nervous system, larvae L3  (2063) central nervous system, pupae P8  (819) head, virgin 1-day female  (842) head, virgin 4-day female  (1118) head, virgin 20-day female  (1066) head, mated 1-day female  (755) head, mated 4-day female  (1126) head, mated 20-day female  (878) head, mated 1-day male  (954) head, mated 4-day male  (1202) head, mated 20-day male  (1296) salivary gland, larvae L3 wandering  (127) salivary gland, white prepupae  (848) digestive system, larvae L3 wandering  (1742) digestive system, 1-day adult  (1244) digestive system, 4-day adult  (1506) digestive system, 20-day adult  (1717) fat body, larvae L3 wandering  (687) fat body, white prepupae  (1014) fat body, pupae P8  (932) carcass, larvae L3 wandering  (2218) carcass, 1-day adult  (844) carcass, 4-day adult  (1506) carcass, 20-day adult  (1595) ovary, virgin 4-day female  (2180) ovary, mated 4-day female  (2435) testis, mated 4-day male  (990) accessory gland, mated 4-day male  (768) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2206 central nervous system, larvae L3    2063 central nervous system, pupae P8    819 head, virgin 1-day female    842 head, virgin 4-day female    1118 head, virgin 20-day female    1066 head, mated 1-day female    755 head, mated 4-day female    1126 head, mated 20-day female    878 head, mated 1-day male    954 head, mated 4-day male    1202 head, mated 20-day male    1296 salivary gland, larvae L3 wandering    127 salivary gland, white prepupae    848 digestive system, larvae L3 wandering    1742 digestive system, 1-day adult    1244 digestive system, 4-day adult    1506 digestive system, 20-day adult    1717 fat body, larvae L3 wandering    687 fat body, white prepupae    1014 fat body, pupae P8    932 carcass, larvae L3 wandering    2218 carcass, 1-day adult    844 carcass, 4-day adult    1506 carcass, 20-day adult    1595 ovary, virgin 4-day female    2180 ovary, mated 4-day female    2435 testis, mated 4-day male    990 accessory gland, mated 4-day male    768 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2206 central nervous system, larvae L3    2063 central nervous system, pupae P8    819 head, virgin 1-day female    842 head, virgin 4-day female    1118 head, virgin 20-day female    1066 head, mated 1-day female    755 head, mated 4-day female    1126 head, mated 20-day female    878 head, mated 1-day male    954 head, mated 4-day male    1202 head, mated 20-day male    1296 salivary gland, larvae L3 wandering    127 salivary gland, white prepupae    848 digestive system, larvae L3 wandering    1742 digestive system, 1-day adult    1244 digestive system, 4-day adult    1506 digestive system, 20-day adult    1717 fat body, larvae L3 wandering    687 fat body, white prepupae    1014 fat body, pupae P8    932 carcass, larvae L3 wandering    2218 carcass, 1-day adult    844 carcass, 4-day adult    1506 carcass, 20-day adult    1595 ovary, virgin 4-day female    2180 ovary, mated 4-day female    2435 testis, mated 4-day male    990 accessory gland, mated 4-day male    768 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (2206) central nervous system, larvae L3  (2063) central nervous system, pupae P8  (819) head, virgin 1-day female  (842) head, virgin 4-day female  (1118) head, virgin 20-day female  (1066) head, mated 1-day female  (755) head, mated 4-day female  (1126) head, mated 20-day female  (878) head, mated 1-day male  (954) head, mated 4-day male  (1202) head, mated 20-day male  (1296) salivary gland, larvae L3 wandering  (127) salivary gland, white prepupae  (848) digestive system, larvae L3 wandering  (1742) digestive system, 1-day adult  (1244) digestive system, 4-day adult  (1506) digestive system, 20-day adult  (1717) fat body, larvae L3 wandering  (687) fat body, white prepupae  (1014) fat body, pupae P8  (932) carcass, larvae L3 wandering  (2218) carcass, 1-day adult  (844) carcass, 4-day adult  (1506) carcass, 20-day adult  (1595) ovary, virgin 4-day female  (2180) ovary, mated 4-day female  (2435) testis, mated 4-day male  (990) accessory gland, mated 4-day male  (768) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (2206) central nervous system, larvae L3  (2063) central nervous system, pupae P8  (819) head, virgin 1-day female  (842) head, virgin 4-day female  (1118) head, virgin 20-day female  (1066) head, mated 1-day female  (755) head, mated 4-day female  (1126) head, mated 20-day female  (878) head, mated 1-day male  (954) head, mated 4-day male  (1202) head, mated 20-day male  (1296) salivary gland, larvae L3 wandering  127 salivary gland, white prepupae  (848) digestive system, larvae L3 wandering  (1742) digestive system, 1-day adult  (1244) digestive system, 4-day adult  (1506) digestive system, 20-day adult  (1717) fat body, larvae L3 wandering  (687) fat body, white prepupae  (1014) fat body, pupae P8  (932) carcass, larvae L3 wandering  (2218) carcass, 1-day adult  (844) carcass, 4-day adult  (1506) carcass, 20-day adult  (1595) ovary, virgin 4-day female  (2180) ovary, mated 4-day female  (2435) testis, mated 4-day male  (990) accessory gland, mated 4-day male  (768) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2206 central nervous system, larvae L3    2063 central nervous system, pupae P8    819 head, virgin 1-day female    842 head, virgin 4-day female    1118 head, virgin 20-day female    1066 head, mated 1-day female    755 head, mated 4-day female    1126 head, mated 20-day female    878 head, mated 1-day male    954 head, mated 4-day male    1202 head, mated 20-day male    1296 salivary gland, larvae L3 wandering    127 salivary gland, white prepupae    848 digestive system, larvae L3 wandering    1742 digestive system, 1-day adult    1244 digestive system, 4-day adult    1506 digestive system, 20-day adult    1717 fat body, larvae L3 wandering    687 fat body, white prepupae    1014 fat body, pupae P8    932 carcass, larvae L3 wandering    2218 carcass, 1-day adult    844 carcass, 4-day adult    1506 carcass, 20-day adult    1595 ovary, virgin 4-day female    2180 ovary, mated 4-day female    2435 testis, mated 4-day male    990 accessory gland, mated 4-day male    768 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2302 embryo 02-04hr    3186 embryo 04-06hr    2750 embryo 06-08hr    2248 embryo 08-10hr    2169 embryo 10-12hr    2213 embryo 12-14hr    1283 embryo 14-16hr    1910 embryo 16-18hr    1401 embryo 18-20hr    1182 embryo 20-22hr    1227 embryo 22-24hr    1104 larva L1    3273 larva L2    1785 larva L3 12hr old    1493 larva L3 puffstage 1-2    1044 larva L3 puffstage 3-6    1530 larva L3 puffstage 7-9    1646 white prepupae new    1457 white prepupae 12hr    1366 white prepupae 24hr    1170 pupae 2d postWPP    840 pupae 3d postWPP    785 pupae 4d postWPP    1273 adult male 01day    922 adult male 05day    1208 adult male 30day    1458 adult female 01day    2747 adult female 05day    2206 adult female 30day    2313 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2302) embryo 02-04hr  (3186) embryo 04-06hr  (2750) embryo 06-08hr  (2248) embryo 08-10hr  (2169) embryo 10-12hr  (2213) embryo 12-14hr  (1283) embryo 14-16hr  (1910) embryo 16-18hr  (1401) embryo 18-20hr  (1182) embryo 20-22hr  (1227) embryo 22-24hr  (1104) larva L1  (3273) larva L2  (1785) larva L3 12hr old  (1493) larva L3 puffstage 1-2  (1044) larva L3 puffstage 3-6  (1530) larva L3 puffstage 7-9  (1646) white prepupae new  (1457) white prepupae 12hr  (1366) white prepupae 24hr  (1170) pupae 2d postWPP  (840) pupae 3d postWPP  (785) pupae 4d postWPP  (1273) adult male 01day  (922) adult male 05day  (1208) adult male 30day  (1458) adult female 01day  (2747) adult female 05day  (2206) adult female 30day  (2313) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (2302) embryo 02-04hr  (3186) embryo 04-06hr  (2750) embryo 06-08hr  (2248) embryo 08-10hr  (2169) embryo 10-12hr  (2213) embryo 12-14hr  (1283) embryo 14-16hr  (1910) embryo 16-18hr  (1401) embryo 18-20hr  (1182) embryo 20-22hr  (1227) embryo 22-24hr  (1104) larva L1  (3273) larva L2  (1785) larva L3 12hr old  (1493) larva L3 puffstage 1-2  (1044) larva L3 puffstage 3-6  (1530) larva L3 puffstage 7-9  (1646) white prepupae new  (1457) white prepupae 12hr  (1366) white prepupae 24hr  (1170) pupae 2d postWPP  (840) pupae 3d postWPP  (785) pupae 4d postWPP  (1273) adult male 01day  (922) adult male 05day  (1208) adult male 30day  (1458) adult female 01day  (2747) adult female 05day  (2206) adult female 30day  (2313) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2302 embryo 02-04hr    3186 embryo 04-06hr    2750 embryo 06-08hr    2248 embryo 08-10hr    2169 embryo 10-12hr    2213 embryo 12-14hr    1283 embryo 14-16hr    1910 embryo 16-18hr    1401 embryo 18-20hr    1182 embryo 20-22hr    1227 embryo 22-24hr    1104 larva L1    3273 larva L2    1785 larva L3 12hr old    1493 larva L3 puffstage 1-2    1044 larva L3 puffstage 3-6    1530 larva L3 puffstage 7-9    1646 white prepupae new    1457 white prepupae 12hr    1366 white prepupae 24hr    1170 pupae 2d postWPP    840 pupae 3d postWPP    785 pupae 4d postWPP    1273 adult male 01day    922 adult male 05day    1208 adult male 30day    1458 adult female 01day    2747 adult female 05day    2206 adult female 30day    2313 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2302 embryo 02-04hr    3186 embryo 04-06hr    2750 embryo 06-08hr    2248 embryo 08-10hr    2169 embryo 10-12hr    2213 embryo 12-14hr    1283 embryo 14-16hr    1910 embryo 16-18hr    1401 embryo 18-20hr    1182 embryo 20-22hr    1227 embryo 22-24hr    1104 larva L1    3273 larva L2    1785 larva L3 12hr old    1493 larva L3 puffstage 1-2    1044 larva L3 puffstage 3-6    1530 larva L3 puffstage 7-9    1646 white prepupae new    1457 white prepupae 12hr    1366 white prepupae 24hr    1170 pupae 2d postWPP    840 pupae 3d postWPP    785 pupae 4d postWPP    1273 adult male 01day    922 adult male 05day    1208 adult male 30day    1458 adult female 01day    2747 adult female 05day    2206 adult female 30day    2313 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2302) embryo 02-04hr  (3186) embryo 04-06hr  (2750) embryo 06-08hr  (2248) embryo 08-10hr  (2169) embryo 10-12hr  (2213) embryo 12-14hr  (1283) embryo 14-16hr  (1910) embryo 16-18hr  (1401) embryo 18-20hr  (1182) embryo 20-22hr  (1227) embryo 22-24hr  (1104) larva L1  (3273) larva L2  (1785) larva L3 12hr old  (1493) larva L3 puffstage 1-2  (1044) larva L3 puffstage 3-6  (1530) larva L3 puffstage 7-9  (1646) white prepupae new  (1457) white prepupae 12hr  (1366) white prepupae 24hr  (1170) pupae 2d postWPP  (840) pupae 3d postWPP  (785) pupae 4d postWPP  (1273) adult male 01day  (922) adult male 05day  (1208) adult male 30day  (1458) adult female 01day  (2747) adult female 05day  (2206) adult female 30day  (2313) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (2302) embryo 02-04hr  (3186) embryo 04-06hr  (2750) embryo 06-08hr  (2248) embryo 08-10hr  (2169) embryo 10-12hr  (2213) embryo 12-14hr  (1283) embryo 14-16hr  (1910) embryo 16-18hr  (1401) embryo 18-20hr  (1182) embryo 20-22hr  (1227) embryo 22-24hr  (1104) larva L1  (3273) larva L2  (1785) larva L3 12hr old  (1493) larva L3 puffstage 1-2  (1044) larva L3 puffstage 3-6  (1530) larva L3 puffstage 7-9  (1646) white prepupae new  (1457) white prepupae 12hr  (1366) white prepupae 24hr  (1170) pupae 2d postWPP  (840) pupae 3d postWPP  (785) pupae 4d postWPP  (1273) adult male 01day  (922) adult male 05day  (1208) adult male 30day  (1458) adult female 01day  (2747) adult female 05day  (2206) adult female 30day  (2313) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2302 embryo 02-04hr    3186 embryo 04-06hr    2750 embryo 06-08hr    2248 embryo 08-10hr    2169 embryo 10-12hr    2213 embryo 12-14hr    1283 embryo 14-16hr    1910 embryo 16-18hr    1401 embryo 18-20hr    1182 embryo 20-22hr    1227 embryo 22-24hr    1104 larva L1    3273 larva L2    1785 larva L3 12hr old    1493 larva L3 puffstage 1-2    1044 larva L3 puffstage 3-6    1530 larva L3 puffstage 7-9    1646 white prepupae new    1457 white prepupae 12hr    1366 white prepupae 24hr    1170 pupae 2d postWPP    840 pupae 3d postWPP    785 pupae 4d postWPP    1273 adult male 01day    922 adult male 05day    1208 adult male 30day    1458 adult female 01day    2747 adult female 05day    2206 adult female 30day    2313 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2706 Schneider line 2 Sg4    3464 embryonic 1182-4H    2407 embryonic GM2    3262 embryonic Kc167    1591 embryonic S1    4750 embryonic S3    2071 leg disc CME L1    4250 wing disc CME-W2    2627 wing disc ML-DmD8    1933 wing disc ML-DmD9    4830 wing disc ML-DmD16-c3    2183 wing disc ML-DmD21    4332 wing disc ML-DmD32    4162 haltere disc ML-DmD17-c3    2436 eye-antennal disc ML-DmD11    3190 antennal disc ML-DmD20-c5    2352 mixed discs ML-DmD4-c1    2752 CNS ML-DmBG1-c1    2950 CNS ML-DmBG2-c2    2155 tumorous blood cells mbn2    1710 ovary fGS/OSS    7421 ovary OSC    3495 ovary OSS    2267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2706) Schneider line 2 Sg4  (3464) embryonic 1182-4H  (2407) embryonic GM2  (3262) embryonic Kc167  (1591) embryonic S1  (4750) embryonic S3  (2071) leg disc CME L1  (4250) wing disc CME-W2  (2627) wing disc ML-DmD8  (1933) wing disc ML-DmD9  (4830) wing disc ML-DmD16-c3  (2183) wing disc ML-DmD21  (4332) wing disc ML-DmD32  (4162) haltere disc ML-DmD17-c3  (2436) eye-antennal disc ML-DmD11  (3190) antennal disc ML-DmD20-c5  (2352) mixed discs ML-DmD4-c1  (2752) CNS ML-DmBG1-c1  (2950) CNS ML-DmBG2-c2  (2155) tumorous blood cells mbn2  (1710) ovary fGS/OSS  (7421) ovary OSC  (3495) ovary OSS  (2267) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2706) Schneider line 2 Sg4  (3464) embryonic 1182-4H  (2407) embryonic GM2  (3262) embryonic Kc167  (1591) embryonic S1  (4750) embryonic S3  (2071) leg disc CME L1  (4250) wing disc CME-W2  (2627) wing disc ML-DmD8  (1933) wing disc ML-DmD9  (4830) wing disc ML-DmD16-c3  (2183) wing disc ML-DmD21  (4332) wing disc ML-DmD32  (4162) haltere disc ML-DmD17-c3  (2436) eye-antennal disc ML-DmD11  (3190) antennal disc ML-DmD20-c5  (2352) mixed discs ML-DmD4-c1  (2752) CNS ML-DmBG1-c1  (2950) CNS ML-DmBG2-c2  (2155) tumorous blood cells mbn2  (1710) ovary fGS/OSS  (7421) ovary OSC  (3495) ovary OSS  (2267) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2706 Schneider line 2 Sg4    3464 embryonic 1182-4H    2407 embryonic GM2    3262 embryonic Kc167    1591 embryonic S1    4750 embryonic S3    2071 leg disc CME L1    4250 wing disc CME-W2    2627 wing disc ML-DmD8    1933 wing disc ML-DmD9    4830 wing disc ML-DmD16-c3    2183 wing disc ML-DmD21    4332 wing disc ML-DmD32    4162 haltere disc ML-DmD17-c3    2436 eye-antennal disc ML-DmD11    3190 antennal disc ML-DmD20-c5    2352 mixed discs ML-DmD4-c1    2752 CNS ML-DmBG1-c1    2950 CNS ML-DmBG2-c2    2155 tumorous blood cells mbn2    1710 ovary fGS/OSS    7421 ovary OSC    3495 ovary OSS    2267 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2706 Schneider line 2 Sg4    3464 embryonic 1182-4H    2407 embryonic GM2    3262 embryonic Kc167    1591 embryonic S1    4750 embryonic S3    2071 leg disc CME L1    4250 wing disc CME-W2    2627 wing disc ML-DmD8    1933 wing disc ML-DmD9    4830 wing disc ML-DmD16-c3    2183 wing disc ML-DmD21    4332 wing disc ML-DmD32    4162 haltere disc ML-DmD17-c3    2436 eye-antennal disc ML-DmD11    3190 antennal disc ML-DmD20-c5    2352 mixed discs ML-DmD4-c1    2752 CNS ML-DmBG1-c1    2950 CNS ML-DmBG2-c2    2155 tumorous blood cells mbn2    1710 ovary fGS/OSS    7421 ovary OSC    3495 ovary OSS    2267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2706) Schneider line 2 Sg4  (3464) embryonic 1182-4H  (2407) embryonic GM2  (3262) embryonic Kc167  (1591) embryonic S1  (4750) embryonic S3  (2071) leg disc CME L1  (4250) wing disc CME-W2  (2627) wing disc ML-DmD8  (1933) wing disc ML-DmD9  (4830) wing disc ML-DmD16-c3  (2183) wing disc ML-DmD21  (4332) wing disc ML-DmD32  (4162) haltere disc ML-DmD17-c3  (2436) eye-antennal disc ML-DmD11  (3190) antennal disc ML-DmD20-c5  (2352) mixed discs ML-DmD4-c1  (2752) CNS ML-DmBG1-c1  (2950) CNS ML-DmBG2-c2  (2155) tumorous blood cells mbn2  (1710) ovary fGS/OSS  (7421) ovary OSC  (3495) ovary OSS  (2267) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2706) Schneider line 2 Sg4  (3464) embryonic 1182-4H  (2407) embryonic GM2  (3262) embryonic Kc167  (1591) embryonic S1  (4750) embryonic S3  (2071) leg disc CME L1  (4250) wing disc CME-W2  (2627) wing disc ML-DmD8  (1933) wing disc ML-DmD9  (4830) wing disc ML-DmD16-c3  (2183) wing disc ML-DmD21  (4332) wing disc ML-DmD32  (4162) haltere disc ML-DmD17-c3  (2436) eye-antennal disc ML-DmD11  (3190) antennal disc ML-DmD20-c5  (2352) mixed discs ML-DmD4-c1  (2752) CNS ML-DmBG1-c1  (2950) CNS ML-DmBG2-c2  (2155) tumorous blood cells mbn2  (1710) ovary fGS/OSS  (7421) ovary OSC  (3495) ovary OSS  (2267) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2706 Schneider line 2 Sg4    3464 embryonic 1182-4H    2407 embryonic GM2    3262 embryonic Kc167    1591 embryonic S1    4750 embryonic S3    2071 leg disc CME L1    4250 wing disc CME-W2    2627 wing disc ML-DmD8    1933 wing disc ML-DmD9    4830 wing disc ML-DmD16-c3    2183 wing disc ML-DmD21    4332 wing disc ML-DmD32    4162 haltere disc ML-DmD17-c3    2436 eye-antennal disc ML-DmD11    3190 antennal disc ML-DmD20-c5    2352 mixed discs ML-DmD4-c1    2752 CNS ML-DmBG1-c1    2950 CNS ML-DmBG2-c2    2155 tumorous blood cells mbn2    1710 ovary fGS/OSS    7421 ovary OSC    3495 ovary OSS    2267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2016 cold shock, 4-day adult    1688 heat shock, 4-day adult    2482 Cadmium 50 mM 6 hrs, larvae L3    1403 Cadmium 50 mM 12 hrs, larvae L3    863 Cadmium 50 mM 48 hrs, 4-day adult    1874 Cadmium 100 mM 48 hrs, 4-day adult    2669 Copper 0.5 mM 12 hrs, larvae L3    1591 Copper 15 mM 48 hrs, 4-day adult    2161 Zinc 5 mM 12 hrs, larvae L3    1205 Zinc 4.5 mM 48 hrs, 4-day adult    1602 Ethanol 2.5% 3 hrs, larvae L3    3258 Ethanol 5% 3 hrs, larvae L3    1244 Ethanol 10% 3 hrs, larvae L3    1664 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1039 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2059 Caffeine 25 mg/ml 48 hrs, 4-day adult    1535 Paraquat 5 mM 48 hrs, 4-day adult    2196 Paraquat 10 mM 48 hrs, 4-day adult    3082 Rotenone 2 μg 12 hrs, larvae L3    1527 Rotenone 8 μg 12 hrs, larvae L3    2120 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (2016) cold shock, 4-day adult  (1688) heat shock, 4-day adult  (2482) Cadmium 50 mM 6 hrs, larvae L3  (1403) Cadmium 50 mM 12 hrs, larvae L3  (863) Cadmium 50 mM 48 hrs, 4-day adult  (1874) Cadmium 100 mM 48 hrs, 4-day adult  (2669) Copper 0.5 mM 12 hrs, larvae L3  (1591) Copper 15 mM 48 hrs, 4-day adult  (2161) Zinc 5 mM 12 hrs, larvae L3  (1205) Zinc 4.5 mM 48 hrs, 4-day adult  (1602) Ethanol 2.5% 3 hrs, larvae L3  (3258) Ethanol 5% 3 hrs, larvae L3  (1244) Ethanol 10% 3 hrs, larvae L3  (1664) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1039) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (2059) Caffeine 25 mg/ml 48 hrs, 4-day adult  (1535) Paraquat 5 mM 48 hrs, 4-day adult  (2196) Paraquat 10 mM 48 hrs, 4-day adult  (3082) Rotenone 2 μg 12 hrs, larvae L3  (1527) Rotenone 8 μg 12 hrs, larvae L3  (2120) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (2016) cold shock, 4-day adult  (1688) heat shock, 4-day adult  (2482) Cadmium 50 mM 6 hrs, larvae L3  (1403) Cadmium 50 mM 12 hrs, larvae L3  (863) Cadmium 50 mM 48 hrs, 4-day adult  (1874) Cadmium 100 mM 48 hrs, 4-day adult  (2669) Copper 0.5 mM 12 hrs, larvae L3  (1591) Copper 15 mM 48 hrs, 4-day adult  (2161) Zinc 5 mM 12 hrs, larvae L3  (1205) Zinc 4.5 mM 48 hrs, 4-day adult  (1602) Ethanol 2.5% 3 hrs, larvae L3  (3258) Ethanol 5% 3 hrs, larvae L3  (1244) Ethanol 10% 3 hrs, larvae L3  (1664) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1039) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (2059) Caffeine 25 mg/ml 48 hrs, 4-day adult  (1535) Paraquat 5 mM 48 hrs, 4-day adult  (2196) Paraquat 10 mM 48 hrs, 4-day adult  (3082) Rotenone 2 μg 12 hrs, larvae L3  (1527) Rotenone 8 μg 12 hrs, larvae L3  (2120) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2016 cold shock, 4-day adult    1688 heat shock, 4-day adult    2482 Cadmium 50 mM 6 hrs, larvae L3    1403 Cadmium 50 mM 12 hrs, larvae L3    863 Cadmium 50 mM 48 hrs, 4-day adult    1874 Cadmium 100 mM 48 hrs, 4-day adult    2669 Copper 0.5 mM 12 hrs, larvae L3    1591 Copper 15 mM 48 hrs, 4-day adult    2161 Zinc 5 mM 12 hrs, larvae L3    1205 Zinc 4.5 mM 48 hrs, 4-day adult    1602 Ethanol 2.5% 3 hrs, larvae L3    3258 Ethanol 5% 3 hrs, larvae L3    1244 Ethanol 10% 3 hrs, larvae L3    1664 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1039 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2059 Caffeine 25 mg/ml 48 hrs, 4-day adult    1535 Paraquat 5 mM 48 hrs, 4-day adult    2196 Paraquat 10 mM 48 hrs, 4-day adult    3082 Rotenone 2 μg 12 hrs, larvae L3    1527 Rotenone 8 μg 12 hrs, larvae L3    2120 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2016 cold shock, 4-day adult    1688 heat shock, 4-day adult    2482 Cadmium 50 mM 6 hrs, larvae L3    1403 Cadmium 50 mM 12 hrs, larvae L3    863 Cadmium 50 mM 48 hrs, 4-day adult    1874 Cadmium 100 mM 48 hrs, 4-day adult    2669 Copper 0.5 mM 12 hrs, larvae L3    1591 Copper 15 mM 48 hrs, 4-day adult    2161 Zinc 5 mM 12 hrs, larvae L3    1205 Zinc 4.5 mM 48 hrs, 4-day adult    1602 Ethanol 2.5% 3 hrs, larvae L3    3258 Ethanol 5% 3 hrs, larvae L3    1244 Ethanol 10% 3 hrs, larvae L3    1664 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1039 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2059 Caffeine 25 mg/ml 48 hrs, 4-day adult    1535 Paraquat 5 mM 48 hrs, 4-day adult    2196 Paraquat 10 mM 48 hrs, 4-day adult    3082 Rotenone 2 μg 12 hrs, larvae L3    1527 Rotenone 8 μg 12 hrs, larvae L3    2120 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (2016) cold shock, 4-day adult  (1688) heat shock, 4-day adult  (2482) Cadmium 50 mM 6 hrs, larvae L3  (1403) Cadmium 50 mM 12 hrs, larvae L3  (863) Cadmium 50 mM 48 hrs, 4-day adult  (1874) Cadmium 100 mM 48 hrs, 4-day adult  (2669) Copper 0.5 mM 12 hrs, larvae L3  (1591) Copper 15 mM 48 hrs, 4-day adult  (2161) Zinc 5 mM 12 hrs, larvae L3  (1205) Zinc 4.5 mM 48 hrs, 4-day adult  (1602) Ethanol 2.5% 3 hrs, larvae L3  (3258) Ethanol 5% 3 hrs, larvae L3  (1244) Ethanol 10% 3 hrs, larvae L3  (1664) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1039) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (2059) Caffeine 25 mg/ml 48 hrs, 4-day adult  (1535) Paraquat 5 mM 48 hrs, 4-day adult  (2196) Paraquat 10 mM 48 hrs, 4-day adult  (3082) Rotenone 2 μg 12 hrs, larvae L3  (1527) Rotenone 8 μg 12 hrs, larvae L3  (2120) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (2016) cold shock, 4-day adult  (1688) heat shock, 4-day adult  (2482) Cadmium 50 mM 6 hrs, larvae L3  (1403) Cadmium 50 mM 12 hrs, larvae L3  (863) Cadmium 50 mM 48 hrs, 4-day adult  (1874) Cadmium 100 mM 48 hrs, 4-day adult  (2669) Copper 0.5 mM 12 hrs, larvae L3  (1591) Copper 15 mM 48 hrs, 4-day adult  (2161) Zinc 5 mM 12 hrs, larvae L3  (1205) Zinc 4.5 mM 48 hrs, 4-day adult  (1602) Ethanol 2.5% 3 hrs, larvae L3  (3258) Ethanol 5% 3 hrs, larvae L3  (1244) Ethanol 10% 3 hrs, larvae L3  (1664) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1039) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (2059) Caffeine 25 mg/ml 48 hrs, 4-day adult  (1535) Paraquat 5 mM 48 hrs, 4-day adult  (2196) Paraquat 10 mM 48 hrs, 4-day adult  (3082) Rotenone 2 μg 12 hrs, larvae L3  (1527) Rotenone 8 μg 12 hrs, larvae L3  (2120) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2016 cold shock, 4-day adult    1688 heat shock, 4-day adult    2482 Cadmium 50 mM 6 hrs, larvae L3    1403 Cadmium 50 mM 12 hrs, larvae L3    863 Cadmium 50 mM 48 hrs, 4-day adult    1874 Cadmium 100 mM 48 hrs, 4-day adult    2669 Copper 0.5 mM 12 hrs, larvae L3    1591 Copper 15 mM 48 hrs, 4-day adult    2161 Zinc 5 mM 12 hrs, larvae L3    1205 Zinc 4.5 mM 48 hrs, 4-day adult    1602 Ethanol 2.5% 3 hrs, larvae L3    3258 Ethanol 5% 3 hrs, larvae L3    1244 Ethanol 10% 3 hrs, larvae L3    1664 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1039 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    2059 Caffeine 25 mg/ml 48 hrs, 4-day adult    1535 Paraquat 5 mM 48 hrs, 4-day adult    2196 Paraquat 10 mM 48 hrs, 4-day adult    3082 Rotenone 2 μg 12 hrs, larvae L3    1527 Rotenone 8 μg 12 hrs, larvae L3    2120 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult