Gene model reviewed during 5.44
Gene model reviewed during 5.39
Gene model reviewed during 5.45
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ide using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ide in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Altering Ide expression in insulin-producing cells perturbs organism size, circulating sugar, fecundity and lifespan.
Insulin cleavage products generated by Ide enzyme were compared to the cleavage products of rat Ide: both enzymes cleave the A chain of intact insulin at the same sites. Results support the hypothesis that there is evolutionary conservation of Ide and the Ide enzyme plays an important role in cellular function.