Q56, l(1)Q56, YT1, R9-13
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\intro using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\intro in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Complementation mapping and RNAi knockdown data suggests that intro corresponds to CG14619, although the possibility of off-target effects means that this assertion is only tentative and further experiments are required to confirm this.
Many mutants exhibit a pupal lethal phase, although some are larval lethals. Pupal-phase mutants do not contract at the beginning of pupation, remaining slender like larvae. Eye development very rudimentary. Germline clone analysis shows variable lethal phenotypes, including collapsed eggs (Perrimon et al.).
The name 'introvert' is derived from abnormality of some hemizygous pupae in which the head remains inverted within the thorax (Schlosser et al., 1992).