in, engrailed-related
transcription factor - homeodomain - engrailed class - cooperates with in establishing posterior compartment identity
Please see the JBrowse view of Dmel\inv for information on other features
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Gene model reviewed during 5.49
Gene model reviewed during 5.56
2.7 (northern blot)
576 (aa); 60 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\inv using the Feature Mapper tool.
Comment: maternally deposited
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
inv transcripts first appear in embryogensis midway through germ-band elongation, at low levels. At the completion of germ band elongation, inv transcript is expressed in a repeated pattern of 2 to 4 segments. Subsequently, inv is expressed in a pattern coincident with that of its neighboring gene, en, in the posterior compartment of each segment. Both en and inv are also expressed in the hindgut, the labral segment, and ganglia. In third instar larvae, en and inv are expressed in the posterior compartment of wing imaginal discs.
GBrowse - Visual display of RNA-Seq signals
View Dmel\inv in GBrowse 22-64
2-64
2-64.5
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
DNA-protein interactions: genome-wide binding profile assayed for inv protein in 0-12 hr embryos; see mE1_TFBS_inv collection report.
inv gene can play a role in proper development.
Expression pattern of Ecol\lacZ from silencer detector insertions P{lacW}65 and P{en-lacZ(wXba)}invXba21 reflects that of inv.