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Gene Dmel\Ki

General Information
Symbol	Dmel\Ki	Species	D. melanogaster
Name	Kinked	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0001307
Gene Model Status	Unannotated	Stock availability	102 publicly available
Genomic Location
Chromosome (arm)		Recombination map	3-47.6
Cytogenetic map	83D-83E	Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene Kinked is referred to in FlyBase by the symbol Dmel\Ki (FBgn0001307). It is a gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; microchaeta. It has no annotated transcripts. Gene has not been localized to the genome sequence.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Ki: Kinked All bristles and hairs of heterozygote shortened and twisted. Resembles sn. Viability and fertility excellent; classification easy. Homozgyote has more extreme bristle and hair effects. Expression much reduced in flies raised at 18 (Hardy). Ki+ an excellent marker for cuticular clones in Ki/+ heterozygotes. Viability somewhat reduced but fertility near normal. RK1 as heterozygote.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 83D-83E   Left limit from (method unavailable) (FBrf0034851) Right limit from (method unavailable) (FBrf0034851)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	3-47.6
Left of (cM)
Right of (cM)	Kg (Baker, 1980) Su(var)3-3 (Reuter et al., 1986)
Notes	Recovered in newly induced 'C(3R)RM' but not 'C(3L)RM' chromosomes, therefore in 3R. (Lutolf, 1971) Deletions of Ki not obtained, presumably because of close proximity to Tpl. (Kaufman, 1978) In 3R based on mitotic recombination. (Merriam and Garcia-Bellido, 1969)
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Ki1 KiS Sterility Allele fertile Ki1 Other Phenotypes Allele visible | dominant KiS visible | dominant | heat sensitive Ki1 Phenotype manifest in Allele macrochaeta Ki1 KiS microchaeta Ki1 KiS
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Ki Class Mutagen Stocks Known lesion Ki1 spontaneous 102 -- Ki72 ethyl methanesulfonate 0 -- KiS ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ki Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ki allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 102 )
Bloomington	525 Ki1 608 st1 Ki1 pp 1666 Ki1 rnroe-1 pp 4346 Coa1 Ki1 H2/TM1 4368 y1 w1; Ki1 P{Δ2-3}99B 1694 Df(3R)M86D, Ki1 red1 e1/TM6 1718 Ki1 pp Ta2/TM3, Sb1
Kyoto	105964 Ki1 106006 st1 Ki1 pp 107696 Coa1 Ki1 H2/TM1 107710 y1 w1; Ki1 P{Δ2-3}99B 106457 Df(3R)M86D, Ki1 red1 e1/TM6
	More stocks available...
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44519
Antibody Information
Other Information
Discoverer
	R.F. Grell, Dec. 1957.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Mutants do not exhibit defects in the denticle belt of hairs of the larvae. (Dickinson and Thatcher, 1997) Bsb, Ki and Pr dominant mutations result in extremely shortened bristles. (Abbott and Kaufman, 1986) Mutant alleles are useful as markers in clonal analysis. (Lawrence et al., 1986) Mutant individuals display short and twisted bristles and hairs. (Duncan and Kaufman, 1975) Very closely linked to the triplo-lethal region of 83DE; attempts to revert Ki by deletion unsuccessful (Kaufman, 1978) and Ki frequently deleted simultaneously with Tpl (Roehrdanz and Lucchesi, 1980).
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44519
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Ki (Siegel et al., 2004, Wang et al., 2009)
Name Synonym	Kinked (Siegel et al., 2004)
Secondary FlyBase IDs
References ( 26 )
Generate a list of	All references relating to this gene ( 26 )
List References by type	Research paper  ( 21 ) Review  ( 1 ) Personal communication to FlyBase  ( 1 ) Abstract  ( 2 ) Book  ( 1 )
Recent research papers ( 2 )
	Sharp and Agrawal, 2012, Proc. Natl. Acad. Sci. U.S.A. 109(16): 6142--6146 Evidence for elevated mutation rates in low-quality genotypes. [FBrf0218045] Tedman-Aucoin and Agrawal, 2012, Evolution 66(2): 575--585 The effect of deleterious mutations and age on recombination in Drosophila melanogaster. [FBrf0217349] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...