A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Dmel\ks-1

General Information
SymbolDmel\ks-1SpeciesD. melanogaster
Namemale fertility factor ks1Annotation symbol
Feature typegeneFlyBase IDFBgn0001327
Gene Model StatusUnannotated Stock availability 2 publicly available
Genomic Location
Chromosome (arm)Recombination mapY-
Cytogenetic maph22-h22Sequence location
hide Summary Information
Automatically generated summary

See sections below for more information
The gene male fertility factor ks1 is referred to in FlyBase by the symbol Dmel\ks-1 (FBgn0001327). It is a gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 21 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.

User Contributed Data
hide Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage
ks-1
Males deficient for ks-1 sterile. Cross sectional profiles of sperm tails in coiled bundles abnormal in outline; minute tubules ordinarily present among individualized spermtails in coiled bundles missing; replaced by membrane bound vesicles [Hardy, Tokuyasu, and Lindsley, 1981, Chromosoma 83: 593-617 (fig.)]. Within the ks-1 fertility region of the spermatocyte nucleus, a loop-forming site has been demonstrated by antibody staining using the monoclonal S5 (Bonaccorsi et al., 1988). The loops are not visible in living preparations, but like the kl-5 loops, can be stained with the dye CBB.
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Description
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FB2013_03
FB2013_02
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hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
h22-h22  
Left limit from complementation mapping against T(Y;3)R78 (FBrf0039037) Right limit from complementation mapping against T(Y;3)H135 (FBrf0039037)  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Y-
(Hackstein and Hochstenbach, 1995, )
Left of (cM)
Right of (cM)
Notes
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Comments on Gene Model
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Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
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Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
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Type
Symbol & Location
Additional Notes
References
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Linkouts
Crossreferences
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hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
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Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term
Evidence
References
hide Expression Deduced from Reporters
hide High-Throughput Expression Data
Associated Tools
Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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hide modENCODE Anatomy RNA-Seq
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Linkouts
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Sterility
Allele
male sterile
Phenotype manifest in
Allele
hide Classical Alleles ( 21 )
For All Classical Alleles Show

Allele of ks-1ClassMutagenStocksKnown lesion
ks-1J1651 --
ks-1P81 --
ks-1A290 --
ks-1A33
0 --
ks-1B100 --
ks-1B110 --
ks-1B120 --
ks-1B130 --
ks-1B20 --
ks-1B40 --
ks-1B60 --
ks-1B70 --
ks-1B80 --
ks-1E10 --
ks-1G10 --
ks-1S190 --
ks-1S220 --
ks-1S23
0 --
ks-1S24
0 --
ks-1X10 --
ks-1X20 --
hide Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show

Allele of ks-1ClassMutagenStocksKnown lesion
hide Aneuploid Aberrations
Duplicated in
(Kennison, 1981)
Disrupted in
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
 
 
 
 
 
 
 
(Gatti and Pimpinelli, 1983, Bonaccorsi and Lohe, 1991)
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983, Bonaccorsi and Lohe, 1991)
(Gatti and Pimpinelli, 1983, Bonaccorsi and Lohe, 1991)
(Gatti and Pimpinelli, 1983, Bonaccorsi and Lohe, 1991)
(Gatti and Pimpinelli, 1983)
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983, Bonaccorsi and Lohe, 1991)
(Gatti and Pimpinelli, 1983)
(Pisano et al., 1993)
(Zhang and Stankiewicz, 1998)
(Bonaccorsi et al., 1990)
(Bonaccorsi et al., 1990)
(Bonaccorsi et al., 1990)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
Not disrupted in
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Hazelrigg et al., 1982)
(Gatti and Pimpinelli, 1983)
(Gatti and Pimpinelli, 1983)
(Zhang and Stankiewicz, 1998)
(Zhang and Stankiewicz, 1998)
(Zhang and Stankiewicz, 1998)
(Zhang and Stankiewicz, 1998)
(Zhang and Stankiewicz, 1998)
(Bonaccorsi et al., 1990)
(Hazelrigg et al., 1982)
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
Insertions
Type of insertions
Name
Expression data
hide Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
hide Terms Based on Experimental Evidence ( 0 terms )
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
gene
 
hide Interactions & Pathways
hide Summary of Physical Interactions
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
ks-1 allele
Gene
References
hide External Data
Linkouts
hide Orthologs
hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
hide Human Orthologs (0)
Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 2 )
Bloomington
2751
T(Y;2)P8, BS, ks-1P8 y+/SM1; C(1)RM, y1/C(1;Y)1, y1
2727
T(Y;2)J165, esgdgl, BS, ks-1J165 y+/SM1; C(1)RM, y1/C(1;Y)1, y1
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hide cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
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Linkouts
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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Source for database identity of
Source for database merge of
Additional comments
Williamson (1972) reported 26 non-complementing and nine complementing alleles induced by EMS.
 
hide Other Comments
Primary spermatocyte nuclei exhibit three giant lampbrush-like loops formed by the kl-5, kl-3 and ks-1 Y chromosome fertility factors.
(Pisano et al., 1993)
AAGAC satellite DNA repeats which map to the kl-5 and ks-1 loop forming regions are abundantly transcribed in primary spermatocytes. These transcripts are detected at all stages of development of these two loops, do not appear to migrate to the cytoplasm and are degraded when the loops disintegrate during the first meiotic prophase.
(Bonaccorsi et al., 1990)
Males deficient for ks-1 sterile. Cross-sectional profiles of sperm tails in coiled bundles abnormal in outline; minute tubules ordinarily present among individualized spermtails in coiled bundles missing; replaced by membrane bound vesicles (Hardy, Tokuyasu and Lindsley, 1981). Within the ks-1 fertility region of the spermatocyte nucleus, a loop-forming site has been demonstrated by antibody staining using the monoclonal S5 (Bonaccorsi et al., 1988). The loops are not visible in living preparations, but like the kl-5 loops, can be stained with the dye CBB.
 
hide External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
ks-1
(Pisano et al., 1993, Piergentili, 2006)
Sms1
(Hazelrigg et al., 1982, )
Name Synonym
male fertility factor ks1
 
Secondary FlyBase IDs
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