Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ks-1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ks-1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Williamson (1972) reported 26 non-complementing and nine complementing alleles induced by EMS.
AAGAC satellite DNA repeats which map to the kl-5 and ks-1 loop forming regions are abundantly transcribed in primary spermatocytes. These transcripts are detected at all stages of development of these two loops, do not appear to migrate to the cytoplasm and are degraded when the loops disintegrate during the first meiotic prophase.
Males deficient for ks-1 sterile. Cross-sectional profiles of sperm tails in coiled bundles abnormal in outline; minute tubules ordinarily present among individualized spermtails in coiled bundles missing; replaced by membrane bound vesicles (Hardy, Tokuyasu and Lindsley, 1981). Within the ks-1 fertility region of the spermatocyte nucleus, a loop-forming site has been demonstrated by antibody staining using the monoclonal S5 (Bonaccorsi et al., 1988). The loops are not visible in living preparations, but like the kl-5 loops, can be stained with the dye CBB.