Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\l(2)25Ca using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\l(2)25Ca in GBrowse 2
2-14 +/- 1.0
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
may be allelic to l(2)DTS20 may be allelic to l(2)DTS100 may be allelic to l(2)DTS486 may be allelic to l(2)DTS513 may be allelic to l(2)DTS91
Wild type larvae develop membranes that do not change their physical state within the given temperature range independently of the changes in saturated/unsaturated ratios of fatty acid membrane components. Mutant larvae starting development at the restrictive temperature acquire a different membrane structure which cannot be normalised by shifting down to the permissive temperature.
Mutant alleles were selected as dominant temperature-sensitive, dominant cold-sensitive lethal, or recessive lethal mutations, or recessive lethal mutations (Suzuki and Procunier, 1969).
Heterozygotes for dominant temperature-sensitive alleles lethal or nearly so when raised at 29oC but survive at 25oC; +/+/l heterozygotes survive development at 29oC. Heterozygotes for dominant cold-sensitive alleles lethal or nearly so when raised at 17oC but survive at 22oC; adults insensitive to 17oC. Heat-sensitive period 18-24 hr after oviposition; lethal phase varies, but most frequently at 75-90 hr for temperature-sensitive alleles and late in development, but highly variable for cold-sensitive alleles. Heterozygotes for alleles selected as recessive lethals are mostly not dominant temperature-sensitives.