FB2020_02, released Apr 14, 2020

Gene: Dmel\Pgant35A

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General Information
Symbol
Dmel\Pgant35A
Species
D. melanogaster
Name
Polypeptide N-acetylgalactosaminyltransferase 35A
Annotation Symbol
CG7480
Feature Type
protein_coding_gene
FlyBase ID
FBgn0001970
Gene Model Status
Current
Stock Availability
8 publicly available
Enzyme Name (EC)
Polypeptide N-acetylgalactosaminyltransferase (2.4.1.41)
Gene Snapshot
Polypeptide N-acetylgalactosaminyltransferase 35A (Pgant35A) encodes a member of the UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase family. It catalyzes the transfer of a GalNAc sugar onto the hydroxyl groups of serine and threonine in secreted or membrane-bound proteins. The product of Pgant35A is an essential protein involved in epithelial tube polarity. [Date last reviewed: 2019-03-14]
Other Summaries
Also Known As

l(2)35Aa, l(2)br12, br12, BG:DS01068.8 , pgant35

Key Links
Genomic Location
Cytogenetic map
35A4-35A4
Sequence location
2L:14,359,252..14,361,411 [+]
Recombination map

2-50

RefSeq locus
NT_033779 REGION:14359252..14361411
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (Q8MVS5)
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
polypeptide N-acetylgalactosaminyltransferase activity
Predictions / Assertions
Notch binding
Catalytic Activity (EC)
Experimental Evidence
(1) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine (2.4.1.41)
(2) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine (2.4.1.41)
Predictions / Assertions
-
Summaries
Gene Group (FlyBase)
POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES -
Polypeptide N-acetylgalactosaminyltransferase catalyze the transfer of N-Acetylgalactosamine (GalNAc) from UDP-GalNAc to serine and threonine acceptor sites and initiate mucin-type O-glycosylation. (Adapted from FBrf0151358 and FBrf0190815).
Protein Function (UniProtKB)
Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:11925450, PubMed:12829714). Displays the same enzyme activity toward MUC1, MUC4, and EA2 (PubMed:11925450, PubMed:12829714). Not involved in glycosylation of erythropoietin (EPO) (PubMed:11925450). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties (PubMed:11925450, PubMed:12829714). Protein modification by this enzyme might be important for cytokinesis and tube formation during embryogenesis (PubMed:16251381, PubMed:20807760). Together with Pgant3, regulates integrin levels and activity-dependent integrin signaling at the synapse in neurons and muscles (PubMed:25253852).
(UniProt, Q8MVS5)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\Pgant35A or the JBrowse view of Dmel\Pgant35A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.40

Gene model reviewed during 5.45

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Pgant35A-RA
FBtr0080629
NM_143812
2160
632
Additional Transcript Data and Comments
Reported size (kB)

2.2 (northern blot)

(Schwientek et al., 2002)

2.3 (northern blot)

(Ten Hagen and Tran, 2002)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Pgant35A-PA
FBpp0080202
71.8
632
9.04
NP_652069
AAF53391
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

632 (aa)

(Schwientek et al., 2002, Ten Hagen and Tran, 2002)
Comments
External Data
Domain

There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.

The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.

(UniProt, Q8MVS5)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgant35A using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (7 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
polypeptide N-acetylgalactosaminyltransferase activity
inferred from direct assay
(assigned by UniProt )
(Schwientek et al., 2002, Ten Hagen and Tran, 2002)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
Notch binding
inferred from biological aspect of ancestor with PANTHER:PTN000912869
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
oligosaccharide biosynthetic process
inferred from direct assay
(assigned by UniProt )
(Schwientek et al., 2002, Ten Hagen and Tran, 2002)
open tracheal system development
inferred from mutant phenotype
(Tian and Ten Hagen, 2007)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
regulation of Notch signaling pathway
inferred from biological aspect of ancestor with PANTHER:PTN000912869
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
Golgi apparatus
inferred from biological aspect of ancestor with PANTHER:PTN000187024
(assigned by GO_Central )
(Gaudet et al., 2011)
Golgi stack
non-traceable author statement
(assigned by UniProt )
(Ten Hagen and Tran, 2002)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism | ubiquitous

Comment: maternally deposited

(Tian and Ten Hagen, 2006)
embryonic stage 4 -- 6
organism | intense | ubiquitous

Comment: very slight anterior enrichment

(Tian and Ten Hagen, 2006)
embryonic stage 9 -- 11
foregut primordium
(Tian and Ten Hagen, 2006)
anterior midgut primordium
(Tian and Ten Hagen, 2006)
posterior midgut primordium
(Tian and Ten Hagen, 2006)
embryonic stage 12 -- 13
embryonic/larval midgut primordium | posterior
(Tian and Ten Hagen, 2006)
embryonic stage 9 -- 13
hindgut proper primordium
(Tian and Ten Hagen, 2006)
embryonic stage 14 -- 15
embryonic/larval hindgut
(Tian and Ten Hagen, 2006)
embryonic stage 12 -- 15
salivary gland body primordium
(Tian and Ten Hagen, 2006)
embryonic stage 16 -- 17
embryonic/larval salivary gland
(Tian and Ten Hagen, 2006)
embryonic/larval posterior spiracle
(Tian and Ten Hagen, 2006)
embryonic/larval dorsal trunk
(Tian and Ten Hagen, 2006)
third instar larval stage
wing disc | intense | ubiquitous
(Tian and Ten Hagen, 2006)
haltere disc | intense | ubiquitous
(Tian and Ten Hagen, 2006)
ventral thoracic disc | ubiquitous
(Tian and Ten Hagen, 2006)
eye disc | ubiquitous
(Tian and Ten Hagen, 2006)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
oogenesis
germline cell
(Schwientek et al., 2002)
follicle cell
(Schwientek et al., 2002)
adult stage | female
(Schwientek et al., 2002)
ovary
(Schwientek et al., 2002)
adult stage | male
testis
(Schwientek et al., 2002)
(Schwientek et al., 2002)
embryonic stage
organism
(Schwientek et al., 2002)
pcr
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
(Ten Hagen and Tran, 2002)
embryonic stage & larval stage & adult stage
(Ten Hagen and Tran, 2002)
adult stage | male
(Ten Hagen and Tran, 2002)
adult stage | female
(Ten Hagen and Tran, 2002)
Additional Descriptive Data

Pgant35A transcripts are detected in males and females on northern blots. High levels are expressed in the ovary. Lower levels are observed in the testis and in the carcasses. Analysis of unfertilized eggs and early embryos reveals a strong maternal contribution. In situ hybridization during oogenesis reveals expression in germ cells and in follicle epithelia throughout oogenesis.

(Schwientek et al., 2002)

Pgant35A transcripts are detected in all stages from embryo to adult as tested by pcr and northern blot.

(Ten Hagen and Tran, 2002)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Pgant35A in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Pgant35A
Transgenic constructs containing regulatory region of Pgant35A
Deletions and Duplications ( 156 )
Disrupted in
Df(2L)64j
(Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)A47
(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
Df(2L)A215
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A217
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A246
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A263
(Ashburner et al., 1982)
Df(2L)A337
(Fossett et al., 1994)
Df(2L)A376
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A377
(Ashburner et al., 1982)
Df(2L)Adh-nBR100
(Fossett et al., 1994)
Df(2L)Adh-nBR101
(Fossett et al., 1994)
Df(2L)Adh-nBR103
(Fossett et al., 1994)
Df(2L)Adh-nBR117
(Fossett et al., 1994)
Df(2L)Adh-nBR120
(Fossett et al., 1994)
Df(2L)Adh-nBR125
(Fossett et al., 1994)
Df(2L)Adh-nBR130
(Fossett et al., 1994)
Df(2L)Adh-nBR131
(Fossett et al., 1994)
Df(2L)b80e3
(Flores and Engels, 1999, Roote et al., 1996, Ashburner et al., 1982)
Df(2L)b81a1
(Roote et al., 1996, Ashburner et al., 1982)
Df(2L)b83d29a
(Roote et al., 1996, Davis et al., 1990)
Df(2L)b84a2
(Roote et al., 1996, Davis et al., 1990)
Df(2L)b84a4
(Roote et al., 1996)
Df(2L)b84h1
(Flores and Engels, 1999, Roote, 1996.1.30, Roote et al., 1996)
Df(2L)b88h49
(Roote et al., 1996)
Df(2L)el77
(Woodruff and Ashburner, 1979)
Df(2L)EP(2)2039-rv4
(Roote, 2000.6.13)
Df(2L)Exel6035
(Ryder, 2004.4.26)
Df(2L)fn1
(Ashburner et al., 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)fn5
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)fn7
(Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)fn12
(Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)fn26
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)fn30
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)fn31
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)fn36
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)GT4
(Gubb et al., 1990)
Df(2L)GT5
(Gubb et al., 1990)
Df(2L)k08712-rv21
(Roote, 2009.11.24, Roote, 2000.6.13, Ashburner et al., 1999)
Df(2L)ppk1Aid
(Wegman et al., 2010)
Df(2L)TE35B-2
(Gubb et al., 1985)
Df(2L)TE35B-3
(Gubb et al., 1985)
Df(2L)TE35B-4
(Gubb et al., 1985)
Df(2L)TE35B-5
(Gubb et al., 1985)
Df(2L)TE35B-7
(Ashburner et al., 1999, Flores and Engels, 1999, Davis et al., 1997, Roote, 1996.1.30, Roote et al., 1996, Davis et al., 1990, Gubb et al., 1985)
Df(2L)TE35B-8
(Roote et al., 1996, Gubb et al., 1985)
Df(2L)TE35B-9
(Gubb et al., 1985)
Df(2L)TE35B-10
(Gubb et al., 1985)
Df(2L)TE35B-15
(Gubb et al., 1985)
Df(2L)TE35B-300
(Roote et al., 1996)
Df(2L)TE35BC-6
(Gubb et al., 1984)
Df(2L)TE35BC-23
(Gubb et al., 1984)
Df(2L)TE35BC-29
(Gubb et al., 1984)
Df(2L)TE35BC-31
(Gubb et al., 1984)
Df(2L)W
(Ashburner et al., 1982, Woodruff and Ashburner, 1979)
In(2L)75cLC158.1R
(Woodruff and Ashburner, 1979)
In(2L)75c
(Woodruff and Ashburner, 1979)
In(2LR)D20Lnoc4R
(Roote et al., 1996)
T(Y;2)GT2
(Gubb et al., 1990)
Tp(2;3)GT3
(Gubb et al., 1990)
Ts(2Lt;3Rt)GT10+Ts(2Rt;3Lt)TE35B-209
(Roote et al., 1996)
Not disrupted in
Df(2L)A48
(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A63
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A72
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A178
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A220
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A245
(Roote et al., 1996, Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982)
Df(2L)A260
(Davis et al., 1990, Ashburner et al., 1982)
Df(2L)A264
(Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)A266
(Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A267
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A379
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A400
(Flores and Engels, 1999, Roote et al., 1996, Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)
Df(2L)A445
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982)
Df(2L)Adh-nBR102
(Roote et al., 1996, Fossett et al., 1994)
Df(2L)Adh-nBR105
(Fossett et al., 1994)
Df(2L)Adh-nBR106
(Fossett et al., 1994)
Df(2L)Adh-nBR107
(Fossett et al., 1994)
Df(2L)Adh-nBR118
(Fossett et al., 1994)
Df(2L)Adh-nBR119
(Fossett et al., 1994)
Df(2L)Adh-nBR121
(Fossett et al., 1994)
Df(2L)Adh-nBR122
(Fossett et al., 1994)
Df(2L)Adh-nBR126
(Fossett et al., 1994)
Df(2L)Adh-nBR127
(Fossett et al., 1994)
Df(2L)Adh-nBR128
(Fossett et al., 1994)
Df(2L)Adh-nBR129
(Fossett et al., 1994)
Df(2L)ARR1
(Roote et al., 1996, Davis et al., 1990)
Df(2L)b75
(Gubb et al., 1990, Woodruff and Ashburner, 1979)
Df(2L)el14
(Roote et al., 1996, Davis et al., 1990)
Df(2L)el16
(Davis et al., 1990)
Df(2L)el28
(Davis et al., 1990)
Df(2L)el94
(Roote, 1996.1.11, Roote, 1996.8)
Df(2L)fn2
(Roote et al., 1996, Ashburner et al., 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)fn3
(Davis et al., 1990, Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
Df(2L)fn15
(Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)fn27
(Ashburner et al., 1982, Ashburner et al., 1982, O'Donnell et al., 1977)
Df(2L)n78l3
(Ashburner et al., 1982)
Df(2L)osp29
(Roote et al., 1996, Ashburner et al., 1982)
Df(2L)osp144
(Roote et al., 1996, Ashburner et al., 1982)
Df(2L)Scorv4
(Woodruff and Ashburner, 1979)
Df(2L)TE35B-1
(Davis et al., 1990, Gubb et al., 1985)
Df(2L)TE35B-6
(Davis et al., 1990, Gubb et al., 1985)
Df(2L)TE35B-11
(Roote et al., 1996, Gubb et al., 1985)
Df(2L)TE35B-12
(Roote et al., 1996, Gubb et al., 1985)
Df(2L)TE35B-54L
(Roote et al., 1996)
Df(2L)TE35BC-1
(Gubb et al., 1984)
Df(2L)TE35BC-3
(Gubb et al., 1984, Ashburner et al., 1982)
Df(2L)TE35BC-4
(Roote et al., 1996, Gubb et al., 1984, Ashburner et al., 1982)
Df(2L)TE35BC-7
(Gubb et al., 1984)
Df(2L)TE35BC-8
(Davis et al., 1990, Gubb et al., 1984)
Df(2L)TE35BC-24
(Gubb et al., 1984)
Df(2L)TE35BC-28
(Gubb et al., 1984)
Df(2L)TE35BC-34
(Gubb et al., 1984)
Df(2L)TE35BC-35
(Gubb et al., 1984)
Dp(2;2)Cam12
(Roote et al., 1996)
In(2L)C158LScorv11R
(Ashburner and Harrington, 1984)
In(2L)C158LScorv17R
(Ashburner and Harrington, 1984)
In(2L)el9
(Davis et al., 1990)
In(2L)TE35B-13
(Roote, 1996.8, Gubb et al., 1985)
In(2LR)DTD128
(Davis et al., 1990)
In(2LR)el6
(Davis et al., 1990)
In(2LR)el6LA379R
(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)
In(2LR)noc4LScorv9R
(Ashburner and Harrington, 1984)
In(2LR)TE35B-6LScorv9R
(Ashburner and Harrington, 1984)
T(2;3)dpps19
(Davis et al., 1990)
T(2;3)el24
(Davis et al., 1990)
T(2;3)GT8
(Davis et al., 1990)
T(2;3)GT10
(Davis et al., 1990)
T(2;3)Scorv7
(Woodruff and Ashburner, 1979)
T(2;4)GT6
(Roote, 1999.6.8)
T(Y;2)a15
(Davis et al., 1990)
T(Y;2)A80DR15P
(Ashburner et al., 1982, Woodruff and Ashburner, 1979)
T(Y;2)A80
(Davis et al., 1990)
T(Y;2)el4
(Davis et al., 1990)
T(Y;2)GT2
(Roote et al., 1996, Davis et al., 1990)
T(Y;2)J165DP58P
(Woodruff and Ashburner, 1979)
T(Y;2)R15DJ165P
(Woodruff and Ashburner, 1979)
Tp(2;2)A446
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Tp(2;3)GT3
(Roote et al., 1996, Davis et al., 1990)
Ts(2Lt;3Lt)dpps19+Ts(2Rt;3Rt)el24
(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)
Ts(2Lt;3Lt)TE35B-4+Ts(2Rt;3Rt)Scorv13
(Ashburner and Harrington, 1984)
Ts(2Lt;3Lt)TE35B-28+Ts(2Rt;3Rt)osp90
(Roote et al., 1996)
Ts(2Lt;3Lt)TE35BC-3+Ts(2Rt;3Rt)Scorv13
(Ashburner and Harrington, 1984)
Ts(Y;2Lt)a15+Ts(YSt;2Rt)A80
(Roote, 1996.1.11, Roote, 1996.8)
Ts(Y;2Lt)el4+Ts(YSt;2Rt)A80
(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)
Ts(Y;2Lt)el4+Ts(YSt;2Rt)R15
(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996, Ashburner et al., 1982)
Ts(Y;2Lt)GT2+Ts(YSt;2Rt)A80
(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)
Ts(Y;2Lt)TE35B-18+Ts(YSt;2Rt)R15
(Davis et al., 1990)
Duplicated in
Ts(2Lt;4Lt)TE35B-101+Ts(2Rt;4Rt)GT6
(Roote et al., 1996)
Ts(YLt;2Lt)A80+Ts(YLt;2Rt)G74
(Roote et al., 1996)
Not duplicated in
Dp(2;2)TE35B-54L
(Roote et al., 1996)
Dp(2;3)osp3
(Roote et al., 1996)
In(2L)C163.41LC158R
(Roote et al., 1996)
In(2LR)TE35B-226LDTD128R
(Roote et al., 1996)
Ts(Y;2Lt)TE35B-18+Ts(YSt;2Rt)A80
(Roote et al., 1996)
Ts(YLt;2Lt)A80+Ts(Y;2Rt)el4
(Roote et al., 1996)
Ts(YLt;2Lt)R15+Ts(Y;2Rt)el4
(Roote et al., 1996)
Ts(YLt;2Lt)R15+Ts(Y;2Rt)TE35B-18
(Roote et al., 1996)
Ts(YLt;2Lt)R15+Ts(YSt;2Rt)A80
(Roote et al., 1996)
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal, with Scer\GAL4Act5C.PU
lethal, with Scer\GAL4how-24B
lethal, with Scer\GAL4αTub84B.PL
lethal (with Df(2L)b84h1)
lethal | embryonic stage (with Pgant35A1)
lethal | embryonic stage (with Pgant35A3)
lethal | embryonic stage (with Pgant35A4)
lethal | embryonic stage | maternal effect
lethal | embryonic stage | maternal effect (with Pgant35A1)
lethal | embryonic stage | maternal effect (with Pgant35A3)
lethal | embryonic stage | maternal effect (with Pgant35A4)
lethal | larval stage (with Pgant35A1)
lethal | larval stage (with Pgant35A3)
lethal | larval stage (with Pgant35A4)
lethal | larval stage | maternal effect
lethal | larval stage | maternal effect (with Pgant35A3)
lethal | larval stage | maternal effect (with Pgant35A4)
lethal | pupal stage (with Pgant35A1)
lethal | pupal stage (with Pgant35A3)
lethal | pupal stage (with Pgant35A4)
lethal | recessive
lethal - all die before end of embryonic stage | maternal effect
partially lethal - majority die, with Scer\GAL4btl.PS
partially lethal - majority die, with Scer\GAL4c179
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
some die during embryonic stage | maternal effect
wild-type
Phenotype manifest in
Allele
embryonic/larval dorsal trunk (with Pgant35A1)
embryonic/larval dorsal trunk (with Pgant35A3)
embryonic/larval dorsal trunk (with Pgant35A4)
embryonic/larval tracheal system (with Pgant35A1)
embryonic/larval tracheal system (with Pgant35A3)
embryonic/larval tracheal system (with Pgant35A4)
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (22)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\GALNT11
14 of 15
Yes
Yes
 
Hsap\GALNTL5
5 of 15
No
Yes
Hsap\GALNT1
2 of 15
No
No
Hsap\GALNT2
2 of 15
No
No
 
Hsap\GALNT5
2 of 15
No
No
Hsap\GALNT6
2 of 15
No
No
Hsap\GALNT7
2 of 15
No
No
Hsap\GALNT12
2 of 15
No
No
Hsap\GALNT13
2 of 15
No
No
Hsap\GALNT14
2 of 15
No
No
Hsap\GALNT15
2 of 15
No
No
Hsap\GALNT16
2 of 15
No
No
Hsap\POC1B-GALNT4
2 of 15
No
No
Hsap\GALNT3
1 of 15
No
No
Hsap\GALNT4
1 of 15
No
No
Hsap\GALNT8
1 of 15
No
No
Hsap\GALNT9
1 of 15
No
No
Hsap\GALNT10
1 of 15
No
No
Hsap\GALNT17
1 of 15
No
No
Hsap\GALNT18
1 of 15
No
No
Hsap\GALNTL6
1 of 15
No
No
Hsap\PDGFRB
1 of 15
No
No
 
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (19)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Galnt11
14 of 15
Yes
Yes
Mmus\Galntl5
5 of 15
No
Yes
Mmus\Galnt1
2 of 15
No
No
Mmus\Galnt2
2 of 15
No
No
Mmus\Galnt3
2 of 15
No
No
Mmus\Galnt4
2 of 15
No
No
Mmus\Galnt6
2 of 15
No
No
Mmus\Galnt7
2 of 15
No
No
Mmus\Galnt12
2 of 15
No
No
Mmus\Galnt13
2 of 15
No
No
Mmus\Galnt14
2 of 15
No
No
Mmus\Galnt15
2 of 15
No
No
Mmus\Galnt16
2 of 15
No
No
Mmus\Galnt5
1 of 15
No
No
Mmus\Galnt9
1 of 15
No
No
Mmus\Galnt10
1 of 15
No
No
Mmus\Galnt17
1 of 15
No
No
Mmus\Galnt18
1 of 15
No
No
Mmus\Galntl6
1 of 15
No
No
Rattus norvegicus (Norway rat) (18)
Rnor\Galnt11
12 of 13
Yes
Yes
Rnor\Galntl5
5 of 13
No
Yes
Rnor\Galnt1
2 of 13
No
No
Rnor\Galnt2
2 of 13
No
No
Rnor\Galnt3
2 of 13
No
No
Rnor\Galnt5
2 of 13
No
No
Rnor\Galnt6
2 of 13
No
No
Rnor\Galnt7
2 of 13
No
No
Rnor\Galnt12
2 of 13
No
No
Rnor\Galnt13
2 of 13
No
No
Rnor\Galnt14
2 of 13
No
No
Rnor\Galnt15
2 of 13
No
No
Rnor\Galnt16
2 of 13
No
No
Rnor\Galnt4
1 of 13
No
Yes
Rnor\Galnt8
1 of 13
No
Yes
Rnor\Galnt9
1 of 13
No
No
Rnor\Galnt10
1 of 13
No
No
Rnor\Galnt18
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (19)
Xtro\galnt11
7 of 12
Yes
Yes
Xtro\galnt1
2 of 12
No
No
Xtro\galnt2
2 of 12
No
No
Xtro\galnt4
2 of 12
No
No
Xtro\galnt6.1
2 of 12
No
No
Xtro\galnt7
2 of 12
No
No
Xtro\galnt12
2 of 12
No
No
Xtro\galnt13
2 of 12
No
No
Xtro\galnt14
2 of 12
No
No
Xtro\galnt15
2 of 12
No
No
Xtro\galnt16
2 of 12
No
No
Xtro\galnt3
1 of 12
No
No
Xtro\galnt5
1 of 12
No
No
Xtro\galnt6.2
1 of 12
No
No
Xtro\galnt9
1 of 12
No
No
Xtro\galnt10
1 of 12
No
No
Xtro\galnt17
1 of 12
No
No
Xtro\galnt18
1 of 12
No
Yes
Xtro\LOC100498043
1 of 12
No
Yes
Danio rerio (Zebrafish) (21)
Drer\galnt11
11 of 15
Yes
Yes
Drer\galnt1
2 of 15
No
No
Drer\galnt2
2 of 15
No
No
Drer\galnt3
2 of 15
No
No
Drer\galnt5
2 of 15
No
No
Drer\galnt6
2 of 15
No
No
Drer\galnt12
2 of 15
No
No
Drer\galnt13
2 of 15
No
No
Drer\galnt14
2 of 15
No
No
Drer\galnt16
2 of 15
No
No
Drer\poc1bl
2 of 15
No
No
Drer\galnt7
1 of 15
No
No
Drer\galnt8a.2
1 of 15
No
No
Drer\galnt8b.1
1 of 15
No
No
Drer\galnt8b.2
1 of 15
No
No
Drer\galnt9
1 of 15
No
No
Drer\galnt10
1 of 15
No
No
Drer\galnt17
1 of 15
No
No
Drer\galnt18b
1 of 15
No
No
Drer\LOC568645
1 of 15
No
No
Drer\si:ch211-15e22.3
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (9)
Cele\gly-11
11 of 15
Yes
Yes
Cele\gly-8
3 of 15
No
Yes
Cele\gly-3
2 of 15
No
No
Cele\gly-7
2 of 15
No
No
Cele\gly-9
2 of 15
No
No
Cele\gly-4
1 of 15
No
No
Cele\gly-5
1 of 15
No
No
Cele\gly-6
1 of 15
No
No
Cele\gly-10
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091904XC )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00000883
Drosophila simulans
Dsim\GD23962
Drosophila sechellia
Dsec\GM15572
Drosophila erecta
Dere\GG25115
Drosophila yakuba
Dyak\GE19032
Drosophila ananassae
Dana\GF14884
Drosophila pseudoobscura pseudoobscura
Dpse\GA20382
Drosophila persimilis
Dper\GL21271
Drosophila willistoni
Dwil\GK18112
Drosophila virilis
Dvir\GJ18184
Drosophila mojavensis
Dmoj\GI12891
Drosophila grimshawi
Dgri\GH11345
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091502G4 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17013049
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_02559
Mayetiola destructor
Hessian fly
Mdes\Mdes002068
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL008037
Anopheles darlingi
American malaria mosquito
Adar\ADAC000718
Anopheles gambiae
Malaria mosquito
Agam\AGAP004429
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ017883
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W04FY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA000733
Danaus plexippus
Monarch butterfly
Dple\DPOGS203972-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL010375
Apis florea
Little honeybee
Aflo\2601617924
Apis mellifera
Western honey bee
Amel\GB45341
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18647
Bombus terrestris
Buff-tailed bumblebee
Bter\15203020
Linepithema humile
Argentine ant
Lhum\LH12246
Linepithema humile
Argentine ant
Lhum\LH25374
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0023b1
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004093
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08220
Tribolium castaneum
Red flour beetle
Tcas\TC013148
Pediculus humanus
Human body louse
Phum\PHUM498070
Cimex lectularius
Bed bug
Clec\CLEC008235
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI25951
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_12105
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X04CJ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR010899
Ixodes scapularis
Black-legged tick
Isca\ISCW017814
Stegodyphus mimosarum
African social velvet spider
Smim\KFM73354.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g06440
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_224457
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G085O )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt11
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_020919gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-UdpN_act_a_Dgalspp
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt7_3
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt7-2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt10
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt13-2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_028741gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt13
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_028011gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt7
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_019070gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt6
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt7_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt1_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Galnt1-2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_012066gn
Ciona intestinalis
Vase tunicate
Cint\LOC100187006
Ciona intestinalis
Vase tunicate
Cint\LOC100180939
Ciona intestinalis
Vase tunicate
Cint\LOC100176918
Ciona intestinalis
Vase tunicate
Cint\LOC100175975
Ciona intestinalis
Vase tunicate
Cint\LOC100181305
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000005004
Ciona intestinalis
Vase tunicate
Cint\LOC100179270
Gallus gallus
Domestic chicken
Ggal\GALNT5
Gallus gallus
Domestic chicken
Ggal\GALNT14
Gallus gallus
Domestic chicken
Ggal\GALNTL1
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000006665
Gallus gallus
Domestic chicken
Ggal\GALNT2
Gallus gallus
Domestic chicken
Ggal\GALNT13
Gallus gallus
Domestic chicken
Ggal\GALNT12
Gallus gallus
Domestic chicken
Ggal\GALNT10
Gallus gallus
Domestic chicken
Ggal\GALNT11
Gallus gallus
Domestic chicken
Ggal\GALNTL6
Gallus gallus
Domestic chicken
Ggal\GALNT1
Gallus gallus
Domestic chicken
Ggal\GALNT7
Gallus gallus
Domestic chicken
Ggal\GALNT3
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (13)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Pgant2
4 of 10
Pgant7
4 of 10
CG7304
3 of 10
CG7579
3 of 10
CG10000
3 of 10
CG31776
3 of 10
Pgant1
3 of 10
Pgant3
3 of 10
Pgant4
3 of 10
Pgant5
3 of 10
Pgant6
3 of 10
Pgant8
3 of 10
Pgant9
3 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    GALNT11; polypeptide N-acetylgalactosaminyltransferase 11
    14 of 15
    615130
         
        GALNTL5; polypeptide N-acetylgalactosaminyltransferase like 5
        5 of 15
        615133
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            esyN Network Diagram
            Show neighbor-neighbor interactions:
            Select Layout:
            Legend:
            Protein
            RNA
            Selected Interactor(s)
            Interactions Browser
            View in Interactions Browser
            Please see the Physical Interaction reports below for full details
            protein-protein
            Physical Interaction
            Assay
            References
            Pgant35A - Ten-m
            enzymatic study, autoradiography
            (Zhang et al., 2008)
            Summary of Genetic Interactions
            esyN Network Diagram
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            External Data
            Linkouts
            DroID - A comprehensive database of gene and protein interactions.
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            External Data
            Linkouts
            KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            2L
            Recombination map

            2-50

            Cytogenetic map
            35A4-35A4
            Sequence location
            2L:14,359,252..14,361,411 [+]
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            35A4-35A4
            Limits computationally determined from genome sequence between P{lacW}l(2)34Fak00811&P{PZ}wb09437 and P{EP}elBEP2039&P{PZ}osprJ571
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            Experimentally Determined Recombination Data
            Location

            2-50

            (FlyBase, 2016)

            2-46.2

            (Comeron et al., 2012)
            Left of (cM)
            (Roote, 1996.1.30)
            Right of (cM)
            (Woodruff and Ashburner, 1979)
            Notes

            Excisions of Rab14k08712 show that the gene order is ms(2)34Fe, l(2)34Fd, Rab14, Pgant35A.

            (Ashburner et al., 1999.10.12)
            Stocks and Reagents
            Stocks (8)
            Genomic Clones (19)
            cDNA Clones (2)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequences
            BDGP DGC clones
            Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
              Other clones
                RNAi and Array Information
                Linkouts
                DRSC - Results frm RNAi screens
                GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                Antibody Information
                Laboratory Generated Antibodies
                 
                Commercially Available Antibodies
                 
                Other Information
                Relationship to Other Genes
                Source for database identify of

                Source for identity of: Pgant35A l(2)35Aa

                (Ten Hagen and Tran, 2002)
                Source for database merge of

                Source for merge of: l(2)35Aa CG7480

                (Misra, 2000.4.12)
                Additional comments

                The Pgant35A gene may have been derived from the CG10000 gene by retroposition.

                (Pan and Zhang, 2009)

                FlyBase curator comment: "l(2)35Aa" (FBgn0001970, Pgant35A, CG7480) is also referred to in FBrf0151358 as "dGalNAc-T1", but "l(2)35Aa" is not the same gene as the gene with the valid symbol "GalNAc-T1" in FlyBase, which is FBgn0034025, CG8182 described in FBrf0130686 (accession number AF218236).

                (Schwientek et al., 2002)
                Other Comments

                The lethal phenotype of Pgant35A-/Pgant35A- and Df(2L)TE35B-7/Df(2L)b84h1 (with both Pgant35A and spel1 deleted) can be rescued by a fragment of genomic DNA that includes Pgant35A but not spel1.

                (Roote, 1996.1.30)
                Origin and Etymology
                Discoverer
                Etymology
                Identification
                External Crossreferences and Linkouts ( 41 )
                Sequence Crossreferences
                NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                Other crossreferences
                Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                Flygut - An atlas of the Drosophila adult midgut
                GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                InterPro - A database of protein families, domains and functional sites
                KEGG Genes - Molecular building blocks of life in the genomic space.
                modMine - A data warehouse for the modENCODE project
                Linkouts
                DroID - A comprehensive database of gene and protein interactions.
                DRSC - Results frm RNAi screens
                FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                FlyMine - An integrated database for Drosophila genomics
                InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                Synonyms and Secondary IDs (15)
                Reported As
                Symbol Synonym
                A3
                (O'Donnell et al., 1977)
                BG:DS01068.8
                (Ashburner et al., 1999, Ashburner et al., 1999.10.12)
                CG7480
                (Yamamoto-Hino et al., 2015, Dani et al., 2012, Tran et al., 2012, Bennett et al., 2010, Pan and Zhang, 2009, Perkins et al., 2009, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Misra, 2001.4.26)
                GalNAc-T
                (Flores and Engels, 1999)
                Pgant35A
                (Zhang and Ten Hagen, 2019, Aradska et al., 2015, dos Santos, 2014, Czech et al., 2008)
                br12
                (Gubb et al., 1985, Ashburner and Harrington, 1984)
                dGalNAc-T1
                (Wang et al., 2018, Schwientek et al., 2002)
                l(2)35Aa
                (Bennett et al., 2010, Roote, 2009.11.24, Bolshakov et al., 2002, Schwientek et al., 2002, Wilson, 2002, Roote, 2000.6.13, Ashburner et al., 1999, Ashburner et al., 1999, Davis et al., 1997, Roote, 1996.1.11, Roote, 1996.1.30, Roote et al., 1996, Spradling et al., 1995, Davis et al., 1990, Gubb et al., 1990, Gubb et al., 1988)
                l(2)br12
                (The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Gubb et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979)
                l35Aa
                (Fossett et al., 1994)
                pgant35
                (Walski et al., 2017, Ten Hagen et al., 2003)
                pgant35A
                (Wang et al., 2018, Yamamoto-Hino et al., 2015, Dani et al., 2014, Tran et al., 2012, Bennett et al., 2010, Zhang and Ten Hagen, 2010, Zhang et al., 2010, Zhang et al., 2008, Tian and Ten Hagen, 2007, Yi et al., 2007, Tian and Hagen, 2006, Tian and Ten Hagen, 2006, Ten Hagen and Tran, 2002)
                Name Synonyms
                Polypeptide N-acetylgalactosaminyltransferase 35A
                (Ten Hagen and Tran, 2002)
                lethal 12 in the black-reduced region
                (Woodruff and Ashburner, 1979)
                lethal group A3
                (O'Donnell et al., 1977)
                Secondary FlyBase IDs
                • FBgn0027860
                • FBgn0032545
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                Study focus (0)
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                Project
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                References (79)