General Information
Symbol
Dmel\esg
Species
D. melanogaster
Name
escargot
Annotation Symbol
CG3758
Feature Type
FlyBase ID
FBgn0001981
Gene Model Status
Stock Availability
Gene Snapshot
Escargot encodes a Snail-type transcription factor. It contributes to stem cell maintenance, tracheal morphogenesis and neuroblast differentiation. [Date last reviewed: 2016-06-30]
Also Known As
l(2)35Ce, dgl, l(2)br43, BG:DS07851 .7, shof
Genomic Location
Cytogenetic map
Sequence location
2L:15,333,866..15,336,138 [+]
Recombination map
2-51
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
GO Summary Ribbons
Families, Domains and Molecular Function
Gene Group Membership (FlyBase)
Protein Family (UniProt, Sequence Similarities)
Belongs to the snail C2H2-type zinc-finger protein family. (P25932)
Molecular Function (see GO section for details)
Summaries
Gene Group Membership
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
UniProt Contributed Function Data
Transcription factor that can both stimulate and repress transcription. Binds to the consensus DNA sequence 5'-A/GCAGGTG-3'. Regulates cell motility and adhesion during tracheal morphogenesis by stimulating transcription of the DE-cadherin gene shg at branch tips, thereby promoting tracheal tube fusion. Maintains diploidy in imaginal cells by inhibiting the transcription of genes required for endoreplication. Required for development of the genital disk and acts as an intrinsic determinant of wing cell fate. The somatic protein is required for maintenance of male germ cells. Acts with other members of the snail protein family to control embryonic central nervous system development.
(UniProt, P25932)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\esg or the JBrowse view of Dmel\esg for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.52
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0080734
2273
470
Additional Transcript Data and Comments
Reported size (kB)
2.3 (northern blot)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0080293
52.0
470
6.87
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\esg using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (26 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (0 terms)
Biological Process (22 terms)
Terms Based on Experimental Evidence (22 terms)
CV Term
Evidence
References
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from genetic interaction with UniProtKB:P08044
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from direct assay
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred by curator from GO:0003677
(assigned by UniProt )
Expression Data
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
dorsal ectoderm anlage

Comment: anlage in statu nascendi

ventral ectoderm anlage

Comment: anlage in statu nascendi

antennal anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

dorsal head epidermis anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

visual anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

antennal anlage

Comment: reported as procephalic ectoderm anlage

central brain anlage

Comment: reported as procephalic ectoderm anlage

dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

visual anlage

Comment: reported as procephalic ectoderm anlage

antennal primordium

Comment: reported as procephalic ectoderm primordium

central brain primordium

Comment: reported as procephalic ectoderm primordium

visual primordium

Comment: reported as procephalic ectoderm primordium

dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

antennal primordium

Comment: reported as procephalon primordium

central brain primordium

Comment: reported as procephalon primordium

dorsal head epidermis primordium

Comment: reported as head epidermis primordium

lateral head epidermis primordium

Comment: reported as head epidermis primordium

ventral head epidermis primordium

Comment: reported as head epidermis primordium

visual primordium

Comment: reported as procephalon primordium

dorsal imaginal tissue

Comment: reported as dorsal imaginal precursor specific anlage

ventral imaginal tissue

Comment: reported as ventral imaginal precursor specific anlage

northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Expression pattern inferred from unspecified enhancer trap line.
esg transcript is detected in stage 14 of embryogenesis, in presumptive wing, leg, and haltere discs, as well as in the histoblast nests, head, trachea, and the central nervous system. At stage 16, esg transcript is still present in imaginal cells and in the presumptive head. In third instar larvae, esg transcript is expressed in the the central nervous system and in the imaginal discs. esg expression is strongest in the dorsal section of the leg, wing, haltere and eye-antennal discs of third instar larvae.
esg transcripts are expressed throughout embryogenesis and are again detected in pupal stages. In embryos, expression is primarily ectodermal and the pattern is very dynamic. Expression is detected in patches along the dorsal surface in the syncytial blastoderm and at the cellular blastoderm stage. Just prior to gastrulation, the dorsal expression disappears and a grid-like pattern of expression is seen in the neurogenic region of the ventral ectoderm. As germband extension begins, this develops into a pattern of longitudinal stripes in the neurogenic ectoderm. At the beginning of germband retraction, expression is most prominent in the cells of the ventral midline. During germband retraction the pattern is very dynamic including transient expression in cells of the peripheral nervous system. After germband retraction, expression is strong in the leg discs, wing disc, haltere disc and genital disc. Strong expression is also observed in the head region in cells outlining the site of head involution, in the dorsal ridge and in the frontal sac. Staining is also observed in histoblast cells of the abdominal segments.
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
esg protein labels several cells in the leg primordia in stage 15 embryos. However, esg labeling is excluded from the center of the disc. There is significant overlap with Dll staining outside of the center of the disc. All esg positive cells also express hth a marker for proximal trunk and limb primordia. Therefore, esg serves as a cell specific marker for the proximal leg domain in the trunk region.
At stage 5 of embryogenesis, sna protein is expressed ventrally, in the presumptive mesoderm, while esg protein is expressed in the dorsal region. By stage 13, both sna and esg proteins are expressed in presumptive wing and haltere discs. At stage 15, sna and esg proteins are also expressed in the genital disc. The esg protein is detected in the posterior spiracle and in the presumptive leg discs at stage 15, while the sna protein is expressed in a far smaller number of cells in the presumptive leg discs.
Marker for
Subcellular Localization
CV Term
Evidence
References
inferred from direct assay
Expression Deduced from Reporters
Reporter: P{enG}6
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{enG}esgG66
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{esg-lacZ.C2}
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GAL4}esgMH766
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}05730B
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}esgc287a
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}esgNP7397
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}NP5130
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}NP6267
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}p127
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lacW}esg4B7
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lacW}esgB7-2-22
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lacW}esgk00606
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lacW}esgk10811
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lArB}A507.2M2
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{PTT-un}P01986
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{PZ}esg05729
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\esg in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, Transgenic Constructs and Phenotypes
Classical and Insertion Alleles ( 111 )
For All Classical and Insertion Alleles Show
 
Allele of esg
Class
Mutagen
Associated Insertion
Stocks
Known lesion
Other relevant insertions
insertion of enhancer trap binary system
insertion of mobile activating element
Transgenic Constructs ( 16 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of esg
Allele of esg
Mutagen
Associated Transgenic Construct
Stocks
Transgenic constructs containing regulatory region of esg
GAL4 construct
Name
Expression Data
Deletions and Duplications ( 129 )
Disrupted in
Not disrupted in
Summary of Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
leg & trichome | somatic clone, with Scer\GAL4Act5C.PI
macrochaeta & scutum, with Scer\GAL4sca-537.4
microchaeta & scutum, with Scer\GAL4sca-537.4
scutellar bristle & tormogen cell, with Scer\GAL4455.2
scutellar bristle & trichogen cell, with Scer\GAL4455.2
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (10)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
10 of 15
Yes
Yes
6 of 15
No
Yes
6 of 15
No
Yes
2 of 15
No
No
2 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
10 of 15
Yes
Yes
7 of 15
No
Yes
5 of 15
No
No
3 of 15
No
No
3 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (6)
6 of 13
Yes
Yes
6 of 13
Yes
Yes
6 of 13
Yes
Yes
3 of 13
No
No
3 of 13
No
No
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (4)
7 of 12
Yes
Yes
4 of 12
No
Yes
1 of 12
No
Yes
1 of 12
No
Yes
Danio rerio (Zebrafish) (9)
9 of 15
Yes
Yes
4 of 15
No
No
4 of 15
No
No
4 of 15
No
Yes
2 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (7)
8 of 15
Yes
Yes
2 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (4)
1 of 9
Yes
Yes
1 of 9
Yes
No
1 of 9
Yes
Yes
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (0)
No orthologs reported.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190D2I )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508IO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W097C )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X093K )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0Q0V )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Human Disease Model Data
FlyBase Human Disease Model Reports
    Alleles Reported to Model Human Disease (Disease Ontology)
    Download
    Models ( 0 )
    Allele
    Disease
    Evidence
    References
    Interactions ( 1 )
    Allele
    Disease
    Interaction
    References
    Comments ( 0 )
     
    Human Orthologs (via DIOPT v7.1)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser

    Please look at the Interaction Group reports for full details of the physical interactions
    protein-protein
    Interacting group
    Assay
    References
    RNA-RNA
    Interacting group
    Assay
    References
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    suppressible
    suppressible
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    suppressible
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    Pathways
    Gene Group - Pathway Membership (FlyBase)
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2L
    Recombination map
    2-51
    Cytogenetic map
    Sequence location
    2L:15,333,866..15,336,138 [+]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    35D2-35D2
    Limits computationally determined from genome sequence between P{EP}esgEP633&P{PZ}esg07082 and P{lacW}CycEk05007&P{lacW}CycEk02602
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    35D1-35D2
    (determined by in situ hybridisation)
    35D1-35D2
    (determined by in situ hybridisation) 35D1--4 (determined by in situ hybridisation) 35D3--4 (determined by in situ hybridisation) 35C1--3 (determined by in situ hybridisation)
    35E-35E
    (determined by in situ hybridisation)
    35D-35D
    (determined by in situ hybridisation)
    35D1-35D2
    (determined by in situ hybridisation) 35D1--35D4 (determined by in situ hybridisation)
    35C-35C
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Location
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (33)
    Genomic Clones (18)
    cDNA Clones (75)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of
      Source for identity of: esg CG3758
      Source for identity of: esg l(2)35Ce
      Source for database merge of
      Additional comments
      FlyBase curator comment: "EP2370" overexpression phenotype stated to be due to its effect on esg but orientation of the P{EP} element suggests otherwise.
      Other Comments
      The esg product is required for the survival and/or maintenance of secondary and tertiary pigment cells in the eye.
      Expression is enriched in embryonic gonads.
      esg and hth regulate proximodistal patterning in the distal domain of the leg.
      Pairing sensitive alleles do not exhibit long-distance silencing interactions with P-element insertions containing the Mcp-element.
      Expression of tracheal fusion marker genes esg and hdc is induced by activation of the dpp pathway.
      Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.
      esg is necessary for hdc expression in the fusion cells and also sufficient for hdc expression in the cells of the pantip group of the dorsal and lateral branches.
      Expression of esg in the neuroectoderm prefigures that of the ASC genes. Dorsoventral pattern of esg expression in the blastoderm is determined by three independent repressive cues (dpp, sna and twi). Egfr represses esg expression within the intermediate column.
      esg and sna function as intrinsic determinants of wing cell fate.
      esg and sna expression in the wing are maintained by their auto- and crossactivation, and control the same set of genes required for wing development.
      In G2, esg is required to maintain a high level of G2/M cdk (a complex that includes the catalytic subunit encoded by cdc2 and a regulatory subunit G2 cyclin) that actively inhibits the entry into S phase.
      esg is a member of the lymph gland enhancer detector strains.
      esg is required for tracheal branch fusion and inhibits terminal branching by dorsal branch fusion cells.
      esg is a key regulator of cell adhesion and motility in tracheal morphogenesis.
      Overexpression of shg rescues the defect in one of the fusion points in esg mutants.
      esg positively regulates transcription of shg.
      esg is required for the continual renewal of the male germline after pupariation.
      esg is required for expression of many of the genes required for fusion of the separate developing tracheal branching units.
      esg protein is a transcriptional regulator that preferentially binds as a monomer, with high affinity, to a specific sequence (identical to the E2 box) in vitro and acts as a repressor of sc/da-dependent transcription in vivo.
      A pairing sensitive site (PS site) has been identified in regulatory DNA from the esg gene.
      Analysis of mutants suggests that one of the normal functions of esg may be the maintenance of diploidy in imaginal cells.
      esg shows a high degree of similarity with sna.
      5 alleles are discussed but are not named.
      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 62 )
      Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      InterPro - A database of protein families, domains and functional sites
      Linkouts
      ApoDroso - Functional genomic database for photoreceptor development, survival and function
      BioGRID - A database of protein and genetic interactions.
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center cDNA clones
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      FlyMine - An integrated database for Drosophila genomics
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
      KEGG Genes - Molecular building blocks of life in the genomic space.
      modMine - A data warehouse for the modENCODE project
      Synonyms and Secondary IDs (26)
      Reported As
      Symbol Synonym
      esg
      (Na et al., 2018, Nazer et al., 2018, Perochon et al., 2018, Perrimon and Doupé, 2018.5.15, Symonenko et al., 2018, Tan et al., 2018, Tang et al., 2018, Erceg et al., 2017, Jin et al., 2017, Li et al., 2017, Lucchetta and Ohlstein, 2017, Requena et al., 2017, Simões et al., 2017, Transgenic RNAi Project members, 2017-, Jiang et al., 2016, Kockel et al., 2016, Ou et al., 2016, Ramat et al., 2016, Sarov et al., 2016, Apitz and Salecker, 2015, Dutta et al., 2015, Jasper, 2015, Kim et al., 2015, Kohlmaier et al., 2015, Kok et al., 2015, Lu and Li, 2015, Nadimpalli et al., 2015, Sanchez-Díaz et al., 2015, Schertel et al., 2015, Zhai et al., 2015, Biteau and Jasper, 2014, Chandran et al., 2014, Chen and Krasnow, 2014, Ciglar et al., 2014, Driver and Ohlstein, 2014, Huang et al., 2014, Li et al., 2014, Li et al., 2014, Long et al., 2014, Okumura et al., 2014, Rogers and Rogina, 2014, Voog et al., 2014, Aleksic et al., 2013, Bai et al., 2013, Caviglia and Luschnig, 2013, Chen et al., 2013, Djiane et al., 2013, Guo et al., 2013, Guss et al., 2013, Li et al., 2013, Marianes and Spradling, 2013, Pandey et al., 2013, Rera et al., 2013, Roti et al., 2013, Zeng et al., 2013, Zhao et al., 2013, Bond and Foley, 2012, de Navascués et al., 2012, Foronda et al., 2012, Hadar et al., 2012, Hainaut et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Kapuria et al., 2012, Loncle and Williams, 2012, Poernbacher et al., 2012, Popkova et al., 2012, Toledano et al., 2012, Yang et al., 2012, Zhou et al., 2012, Abruzzi et al., 2011, Apidianakis and Rahme, 2011, Bellen et al., 2011, Hartl et al., 2011, Hochmuth et al., 2011, Jiang et al., 2011, Micchelli et al., 2011, Okegbe and DiNardo, 2011, Perdigoto et al., 2011, Pi et al., 2011, Strand and Micchelli, 2011, Takashima et al., 2011, Takashima et al., 2011, Wang et al., 2011, Beebe et al., 2010, Biteau et al., 2010, Buchon et al., 2010, Estella and Mann, 2010, Francis et al., 2010, Jiang et al., 2010, Kazemi-Esfarjani, 2010.6.21, Kim et al., 2010, Magwire et al., 2010, Park et al., 2010, Reis et al., 2010, Salzer et al., 2010, Wang et al., 2010, Zeng et al., 2010, Apidianakis et al., 2009, Buchon et al., 2009, Buchon et al., 2009, Chau et al., 2009, Chung et al., 2009, Flaherty et al., 2009, Grieder et al., 2009, Harbison et al., 2009, Jiang and Edgar, 2009, Jiang et al., 2009, Lee et al., 2009, McKay et al., 2009, Mortimer and Moberg, 2009, Southall and Brand, 2009, Biteau et al., 2008, Cao et al., 2008, Choi et al., 2008, Maeda et al., 2008, Stofanko et al., 2008, Voog et al., 2008, Araujo et al., 2007, Buszczak et al., 2007, Inoue and Hayashi, 2007, Kankel et al., 2007, Kitadate et al., 2007, Li et al., 2007, Minidorff et al., 2007, Minidorff et al., 2007, Mortimer and Moberg, 2007, Quinones-Coello, 2007, Ryder et al., 2007, Sandmann et al., 2007, Singh et al., 2007, Zhang et al., 2007, Armstrong et al., 2006, Casper and Van Doren, 2006, Choksi et al., 2006, Jiang and Crews, 2006, Jung et al., 2006, Le Bras and Van Doren, 2006, Molnar et al., 2006, Negre et al., 2006, Shigenobu et al., 2006, Shigenobu et al., 2006, Bolinger and Boekhoff-Falk, 2005, Brown and Feder, 2005, Kanuka et al., 2005, Staudt et al., 2005, Jiang and Crews, 2003, Streit et al., 2002)
      flg
      l(2)07082
      l(2)4B7
      Name Synonyms
      D.m.Escargot
      double glazed
      Secondary FlyBase IDs
      • FBgn0000445
      • FBgn0011711
      • FBgn0015967
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (417)