FlyBase Gene Report: Dmel\esg

central nervous system

(Hayashi et al., 1993)

dorsal metathoracic disc primordium

(Hayashi et al., 1993)

embryonic stage 14 -- 16

ventral thoracic disc | presumptive

(Hayashi et al., 1993)

wing disc | presumptive

(Hayashi et al., 1993)

(Hayashi et al., 1993)

histoblast nest

(Hayashi et al., 1993)

head

(Hayashi et al., 1993)

embryonic stage 14

embryonic/larval trachea

(Hayashi et al., 1993)

central nervous system

(Hayashi et al., 1993)

adult midgut progenitor cell

(Takashima et al., 2011)

embryonic stage 15 -- 17

gonad

Comment: somatic cells

(Streit et al., 2002)

embryonic stage 4 -- 6

central brain anlage in statu nascendi

(Fisher et al., 2012)

dorsal ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)

ventral ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)

antennal anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)

dorsal head epidermis anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)

visual anlage in statu nascendi

Comment: reported as procephalic ectoderm anlage in statu nascendi

(Fisher et al., 2012)

embryonic stage 7 -- 8

antennal anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)

central brain anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)

dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)

visual anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)

dorsal ectoderm

(Fisher et al., 2012)

ventral ectoderm

(Fisher et al., 2012)

mesectoderm anlage | subset

(Kearney et al., 2004)

embryonic stage 9 -- 10

antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)

anterior endoderm

(Fisher et al., 2012)

dorsal ectoderm

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

ventral ectoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

antennal primordium

Comment: reported as procephalon primordium

(Fisher et al., 2012)

central brain primordium

Comment: reported as procephalon primordium

(Fisher et al., 2012)

dorsal head epidermis primordium

Comment: reported as head epidermis primordium

(Fisher et al., 2012)

lateral head epidermis primordium

Comment: reported as head epidermis primordium

(Fisher et al., 2012)

ventral head epidermis primordium

Comment: reported as head epidermis primordium

(Fisher et al., 2012)

visual primordium

Comment: reported as procephalon primordium

(Fisher et al., 2012)

anterior midgut primordium

(Fisher et al., 2012)

dorsal imaginal tissue

Comment: reported as dorsal imaginal precursor specific anlage

(Fisher et al., 2012)

midline primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

ventral imaginal tissue

Comment: reported as ventral imaginal precursor specific anlage

(Fisher et al., 2012)

ventral nerve cord primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

clypeo-labral disc primordium

(Fisher et al., 2012)

embryonic primordium of adult eye

(Fisher et al., 2012)

atrium

(Fisher et al., 2012)

dorsal imaginal tissue

(Fisher et al., 2012)

embryonic head epidermis

(Fisher et al., 2012)

ventral imaginal tissue

(Fisher et al., 2012)

embryonic stage 9

midline primordium

(Wheeler et al., 2006)

embryonic stage 11

ventral midline

(Wheeler et al., 2006)

cardiogenic mesoderm

(Ahmad et al., 2012)

embryonic stage 9 -- 12

midline primordium | subset

(Kearney et al., 2004)

embryonic stage 10 -- 11

posterior endoderm

(Takashima et al., 2011)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 8 -- 9

ventral neurectoderm

(Whiteley et al., 1992)

embryonic stage 16

(Whiteley et al., 1992)

haltere disc

(Whiteley et al., 1992)

wing disc

(Whiteley et al., 1992)

genital disc

(Whiteley et al., 1992)

prothoracic leg disc

(Whiteley et al., 1992)

metathoracic leg disc

(Whiteley et al., 1992)

dorsal ridge

(Whiteley et al., 1992)

mesothoracic leg disc

(Whiteley et al., 1992)

embryonic stage 11

ventral midline

(Whiteley et al., 1992)

peripheral nervous system

ectoderm

(Whiteley et al., 1992)

embryonic stage 12

(Whiteley et al., 1992)

embryonic stage & pupal stage

(Whiteley et al., 1992)

Additional Descriptive Data

In embryonic stage 10, esg is expressed in the endoderm. At stage 11, the endoderm has split into an outer layer and an inner layer. esg is lost from the outer layer but is maintained transiently in all cells of the inner layer. At stage 14, esg is expressed in a subset of the inner cells that represent the adult midgut progenitors. In larvae and pupae, esg reporters are observed in adult midgut progenitor cells. In pupae, expression is observed in cells that are precursors to the adult intestinal stem cells.

(Takashima et al., 2011)

Expression pattern inferred from unspecified enhancer trap line.

(Kearney et al., 2004)

esg transcript is detected in stage 14 of embryogenesis, in presumptive wing, leg, and haltere discs, as well as in the histoblast nests, head, trachea, and the central nervous system. At stage 16, esg transcript is still present in imaginal cells and in the presumptive head. In third instar larvae, esg transcript is expressed in the the central nervous system and in the imaginal discs. esg expression is strongest in the dorsal section of the leg, wing, haltere and eye-antennal discs of third instar larvae.

(Hayashi et al., 1993)

esg transcripts are expressed throughout embryogenesis and are again detected in pupal stages. In embryos, expression is primarily ectodermal and the pattern is very dynamic. Expression is detected in patches along the dorsal surface in the syncytial blastoderm and at the cellular blastoderm stage. Just prior to gastrulation, the dorsal expression disappears and a grid-like pattern of expression is seen in the neurogenic region of the ventral ectoderm. As germband extension begins, this develops into a pattern of longitudinal stripes in the neurogenic ectoderm. At the beginning of germband retraction, expression is most prominent in the cells of the ventral midline. During germband retraction the pattern is very dynamic including transient expression in cells of the peripheral nervous system. After germband retraction, expression is strong in the leg discs, wing disc, haltere disc and genital disc. Strong expression is also observed in the head region in cells outlining the site of head involution, in the dorsal ridge and in the frontal sac. Staining is also observed in histoblast cells of the abdominal segments.

(Whiteley et al., 1992)

Marker for

adult midgut progenitor cell

(Takashima et al., 2011)

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15

haltere disc

(Fuse et al., 1996)

embryonic/larval anterior spiracle

(Fuse et al., 1996)

ventral thoracic disc | presumptive

(Fuse et al., 1996)

genital disc | presumptive

(Fuse et al., 1996)

wing disc

(Fuse et al., 1996)

ventral thoracic disc primordium | proximal | restricted

Comment: expression excluded from center of disc

(Kubota et al., 2003)

embryonic stage 13

tracheal fusion cell

• nucleus

(Uemura et al., 1996)

wing disc | presumptive

(Fuse et al., 1996)

haltere disc | presumptive

(Fuse et al., 1996)

embryonic stage 5

(Fuse et al., 1996)

embryonic stage 10

neuroblast of ventral nerve cord primordium

(Cai et al., 2001)

embryonic ganglion mother cell

(Cai et al., 2001)

ventral midline neuroblast

(Cai et al., 2001)

embryonic stage 14 -- 17

genital disc primordium

(Chen et al., 2005)

Additional Descriptive Data

esg protein labels several cells in the leg primordia in stage 15 embryos. However, esg labeling is excluded from the center of the disc. There is significant overlap with Dll staining outside of the center of the disc. All esg positive cells also express hth a marker for proximal trunk and limb primordia. Therefore, esg serves as a cell specific marker for the proximal leg domain in the trunk region.

(Kubota et al., 2003)

At stage 5 of embryogenesis, sna protein is expressed ventrally, in the presumptive mesoderm, while esg protein is expressed in the dorsal region. By stage 13, both sna and esg proteins are expressed in presumptive wing and haltere discs. At stage 15, sna and esg proteins are also expressed in the genital disc. The esg protein is detected in the posterior spiracle and in the presumptive leg discs at stage 15, while the sna protein is expressed in a far smaller number of cells in the presumptive leg discs.

(Fuse et al., 1996)

Marker for

genital disc primordium

(Chen et al., 2005)

gonadal somatic stem cell | anterior

(Strand and Micchelli, 2011)

Subcellular Localization

CV Term

Evidence

References

nucleus

inferred from direct assay

(Fuse et al., 1994)

Expression Deduced from Reporters

Reporter:

Stage

Tissue/Position (including subcellular localization)

Reference

dorsal closure stage

amnioserosa | surrounding

(Wada et al., 2007)

amnioserosa | central | variable

(Wada et al., 2007)

Reporter: P{enG}6

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 8 -- 9

ectoderm

(Whiteley et al., 1992)

embryonic stage 13

tracheal fusion cell

(Wolf and Schuh, 2000)

Reporter: P{enG}esg^G66

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15

(DeFalco et al., 2004)

embryonic stage 8 -- 9

ectoderm

(Whiteley et al., 1992)

first instar larval stage | male

hub cell

(Okegbe and DiNardo, 2011)

embryonic stage 17

gonadal sheath proper primordium

(Le Bras and Van Doren, 2006)

hub cell

(Le Bras and Van Doren, 2006)

Reporter: P{esg-lacZ.C2}

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15 & male -- 17 & male

(Streit et al., 2002)

adult stage | male

first instar larval stage

(Streit et al., 2002)

Reporter: P{GAL4}esg^MH766

Stage

Tissue/Position (including subcellular localization)

Reference

larval outer optic anlage

(Apitz and Salecker, 2015)

inner proliferation zone | restricted

(Apitz and Salecker, 2015)

larval outer optic anlage

(Apitz and Salecker, 2015)

inner proliferation zone | restricted

(Apitz and Salecker, 2015)

Reporter: P{GawB}05730B

Stage

Tissue/Position (including subcellular localization)

Reference

imaginal disc epithelial cell of female genital disc

(Keisman et al., 2001)

imaginal disc epithelial cell of male genital disc

(Keisman et al., 2001)

embryonic stage 14 -- 17

genital disc primordium

(Chen et al., 2005)

early third instar larval stage

embryonic/larval spiracular branch

(Weaver and Krasnow, 2008)

third instar larval stage -- adult stage

(Rera et al., 2011)

(Rera et al., 2011)

enterocyte

(Rera et al., 2011)

Reporter: P{GawB}esg^c287a

Stage

Tissue/Position (including subcellular localization)

Reference

antennal mechanosensory and motor center

adult antennal lobe

(Baker et al., 2007)

(Baker et al., 2007)

antennal lobe tract

(Baker et al., 2007)

adult protocerebrum

(Baker et al., 2007)

Reporter: P{GawB}esg^NP7397

Stage

Tissue/Position (including subcellular localization)

Reference

first instar larval stage -- pupal stage P5

midgut imaginal island

(Jiang and Edgar, 2009)

pupal stage P6

(Jiang and Edgar, 2009)

(Jiang et al., 2011)

(Jiang et al., 2011)

Reporter: P{GawB}NP5130

Stage

Tissue/Position (including subcellular localization)

Reference

(Ma et al., 2013, Choi et al., 2008)

(Ma et al., 2013, Choi et al., 2008)

ventral thoracic disc | proximal

(Goto and Hayashi, 1999)

second instar larval stage

ventral thoracic disc | restricted

(Goto and Hayashi, 1999)

(Guo et al., 2013, Buchon et al., 2010)

(Guo et al., 2013)

larval stage -- pupal stage

anterior dorsal histoblast nest abdominal 6

(Foronda et al., 2012)

histoblast nest

(Foronda et al., 2012)

pupal stage | male

(Foronda et al., 2012)

anterior dorsal histoblast nest abdominal 7

(Foronda et al., 2012)

posterior dorsal histoblast nest abdominal 6

(Foronda et al., 2012)

posterior dorsal histoblast nest abdominal 7

(Foronda et al., 2012)

adult stage | female

(Micchelli and Perrimon, 2006)

(Micchelli and Perrimon, 2006)

larval stage

larval imaginal tissue

(Martin and Morata, 2006)

Reporter: P{GawB}NP6267

Stage

Tissue/Position (including subcellular localization)

Reference

intestinal stem cell of posterior adult midgut epithelium

(Maeda et al., 2008)

enteroblast of posterior adult midgut epithelium

(Maeda et al., 2008)

Reporter: P{GawB}p127

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval tracheal system | restricted

(Steneberg et al., 1998)

embryonic stage 13 -- 17

embryonic/larval tracheal system | restricted

(Steneberg et al., 1999)

late third instar larval stage -- pupal stage

embryonic/larval spiracular branch

(Weaver and Krasnow, 2008)

Reporter: P{lacW}esg^4B7

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- larval stage

(Hartenstein and Jan, 1992)

scolopidial dendritic cap cell

(Hartenstein and Jan, 1992)

embryonic stage 13 -- 17

(Hartenstein and Jan, 1992)

oenocyte

(Hartenstein and Jan, 1992)

Reporter: P{lacW}esg^B7-2-22

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval digestive system

(Hartenstein and Jan, 1998.8.10)

segment border muscle | presumptive

(Hartenstein and Jan, 1992)

ventral nerve cord | medial

(Hartenstein and Jan, 1992)

embryonic/larval somatic muscle

(Hartenstein and Jan, 1998.8.10)

presumptive embryonic/larval central nervous system

(Hartenstein and Jan, 1998.8.10)

embryonic/larval tracheal system

(Hartenstein and Jan, 1998.8.10)

embryonic/larval dorsal trunk | segmentally repeated

(Hartenstein and Jan, 1992)

(Hartenstein and Jan, 1992)

Reporter: P{lacW}esg^k00606

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female

(Micchelli and Perrimon, 2006)

(Micchelli and Perrimon, 2006)

Reporter: P{lacW}esg^k10811

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

embryonic/larval oenocyte

(Rodriguez et al., 1996)

mouth hooks

(Rodriguez et al., 1996)

embryonic stage -- larval stage

(Rodriguez et al., 1996)

embryonic/larval lymph gland

(Rodriguez et al., 1996)

adult midgut

(Rodriguez et al., 1996)

adult oenocyte

(Rodriguez et al., 1996)

embryonic/larval posterior spiracle

(Rodriguez et al., 1996)

head

(Rodriguez et al., 1996)

Reporter: P{lArB}A507.2M2

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 17

pole cell

(Bellen et al., 1989)

embryonic/larval posterior spiracle

(Bellen et al., 1989)

embryonic brain

(Bellen et al., 1989)

embryonic stage 15 & male -- 17 & male

(Streit et al., 2002)

adult stage | male

(Streit et al., 2002)

Reporter: P{PTT-un}P01986

Stage

Tissue/Position (including subcellular localization)

Reference

(Guo et al., 2013)

Reporter: P{PZ}esg⁰⁵⁷²⁹

Stage

Tissue/Position (including subcellular localization)

Reference

(Hayashi et al., 1993)

larval imaginal tissue

(Hayashi et al., 1993)

(Hayashi et al., 1993)

(Hayashi et al., 1993)

Reporter: P{ST.lexA::HG}RJ-4

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval central nervous system

ventral nerve cord

(Bloomington Drosophila Stock Center, 2019)

(Bloomington Drosophila Stock Center, 2019)

ring gland

(Bloomington Drosophila Stock Center, 2019)

corpus cardiacum

(Bloomington Drosophila Stock Center, 2019)

embryonic/larval lymph gland

(Bloomington Drosophila Stock Center, 2019)

(Bloomington Drosophila Stock Center, 2019)

Reporter: P{ST.lexA::HG}SE100

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval central nervous system

ventral nerve cord

(Bloomington Drosophila Stock Center, 2019)

(Bloomington Drosophila Stock Center, 2019)

embryonic/larval anterior midgut

(Bloomington Drosophila Stock Center, 2019)

Reporter: P{ST.lexA::HG}SJH-1

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval central nervous system

ventral nerve cord

(Bloomington Drosophila Stock Center, 2019)

(Bloomington Drosophila Stock Center, 2019)

embryonic/larval lymph gland

(Bloomington Drosophila Stock Center, 2019)

(Bloomington Drosophila Stock Center, 2019)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\esg in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\esg

View exonic expression by tissue for Dmel\esg

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0001981

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0001981

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG3758-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG3758

Flygut - An atlas of the Drosophila adult midgut

FBgn0001981

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 111 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 20 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of esg

Transgenic constructs containing regulatory region of esg

Deletions and Duplications ( 129 )

Disrupted in

Df(2L)A48

(Cai et al., 2001, Spradling et al., 1999, Rodriguez et al., 1996, Tanaka-Matakatsu et al., 1996, BDGP Project Members, 1994-1999, Fossett et al., 1994)

Df(2L)A246

(Fossett et al., 1994)

Df(2L)A337

(Fossett et al., 1994)

Df(2L)A376

(Fossett et al., 1994)

Df(2L)Adh-nBR101

(Fossett et al., 1994)

Df(2L)Adh-nBR102

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996, Fossett et al., 1994)

Df(2L)Adh-nBR103

(Fossett et al., 1994)

Df(2L)Adh-nBR118

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996, Fossett et al., 1994)

Df(2L)Adh-nBR120

(Fossett et al., 1994)

Df(2L)Adh-nBR125

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR126

(Fossett et al., 1994)

Df(2L)Adh-nBR130

(Fossett et al., 1994)

Df(2L)b80e4

(Ashburner et al., 1990)

Df(2L)b80k

(Alexandrova et al., 1996)

Df(2L)el20

(Ashburner et al., 1990)

Df(2L)Exel8034

(Ryder, 2004.4.26)

Df(2L)fn26

(Ashburner et al., 1990)

Df(2L)fn27

(Ashburner et al., 1990)

Df(2L)k15711

(Ashburner et al., 1999, Roote, 1998.11.16)

Df(2L)n78l3

(Ashburner et al., 1990)

Df(2L)osp18

(Ashraf et al., 1999, Roote et al., 1996)

Df(2L)osp29

(Cai et al., 2001, Rodriguez et al., 1996, Samakovlis et al., 1996, Kania et al., 1995, BDGP Project Members, 1994-1999, Furukawa et al., 1992)

Df(2L)osp38

(Roote, 1996.8, Ashburner et al., 1990)

Df(2L)PZ07130-mr5

(Roote, 2000.6.13)

Df(2L)Sco7

(Ashburner et al., 1990)

Df(2L)SS1

(Ashburner et al., 1990)

Df(2L)TE35B-1

(Roote et al., 1996)

Df(2L)TE35BC-3

(Cai et al., 2001, Ashburner et al., 1990)

Df(2L)TE35BC-4

(Roote, 1996.8, Roote et al., 1996, Ashburner et al., 1990)

Df(2L)TE35BC-34

(Ashburner et al., 1990)

Df(2L)TE35D-2

(Roote, 1996.8, Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)TE35D-4

(Ashburner et al., 1990)

Df(2L)TE35D-6

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)TE35D-12

(Roote, 1998.11.16)

Df(2L)TE35D-13

(Roote, 1996.8, Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)TE35D-15

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)TE35D-16

(Ashburner et al., 1990)

Df(2L)TE35D-18

(Furukawa et al., 1992)

Df(2L)TE35D-20

(Ashburner et al., 1990)

Df(2L)TE35D-21

(Roote, 1996.8, Ashburner et al., 1990)

Df(2L)TE35D-23

(Ashburner et al., 1990)

Df(2R)nap1

(BDGP Project Members, 1994-1999)

Df(2R)nap2

(BDGP Project Members, 1994-1999)

In(2L)75c

(BDGP Project Members, 1994-1999)

In(2L)dpp^s22Ldpp^d36R

(Ashburner et al., 1990)

In(2L)el18

(Ashburner et al., 1990)

In(2LR)noc^4LSco^rv9R

(Cai et al., 2001)

T(2;3)TE35B-2

(Roote et al., 1996)

Tp(2;2)A446

(Fossett et al., 1994)

Not disrupted in

Df(2L)64j

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)A47

(Fossett et al., 1994)

Df(2L)A63

(Fossett et al., 1994)

Df(2L)A72

(Fossett et al., 1994, Ashburner et al., 1990)

Df(2L)A178

(Fossett et al., 1994)

Df(2L)A215

(Fossett et al., 1994)

Df(2L)A217

(Fossett et al., 1994)

Df(2L)A220

(Fossett et al., 1994)

Df(2L)A245

(Fossett et al., 1994)

Df(2L)A263

(Furukawa et al., 1992)

Df(2L)A264

(Fossett et al., 1994)

Df(2L)A266

(Fossett et al., 1994)

Df(2L)A267

(Cai et al., 2001, Fossett et al., 1994, Ashburner et al., 1990)

Df(2L)A379

(Fossett et al., 1994)

Df(2L)A400

(Fossett et al., 1994)

Df(2L)A445

(Fossett et al., 1994)

Df(2L)Adh-nBR100

(Fossett et al., 1994)

Df(2L)Adh-nBR105

(Fossett et al., 1994)

Df(2L)Adh-nBR106

(Fossett et al., 1994)

Df(2L)Adh-nBR107

(Fossett et al., 1994)

Df(2L)Adh-nBR117

(Fossett et al., 1994)

Df(2L)Adh-nBR119

(Fossett et al., 1994)

Df(2L)Adh-nBR121

(Fossett et al., 1994)

Df(2L)Adh-nBR122

(Fossett et al., 1994)

Df(2L)Adh-nBR127

(Fossett et al., 1994)

Df(2L)Adh-nBR128

(Fossett et al., 1994)

Df(2L)Adh-nBR129

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR131

(Fossett et al., 1994)

Df(2L)ARR1

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)b84a3

(Furukawa et al., 1992)

Df(2L)b84a7

(Furukawa et al., 1992)

Df(2L)b84h50

(BDGP Project Members, 1994-1999, Furukawa et al., 1992)

Df(2L)b87e25

(Kania et al., 1995)

Df(2L)ED3

(Ryder et al., 2007, Ryder and Roote, 2004.11.10, Ryder et al., 2004, Roote, 2002.2.6)

Df(2L)ED800

(Ryder et al., 2007)

Df(2L)ED1000

(Ryder et al., 2007)

Df(2L)el28

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)fn5

(Furukawa et al., 1992)

Df(2L)fn12

(Ashburner et al., 1990)

Df(2L)fn27

(Rodriguez et al., 1996)

Df(2L)H20

(Ashburner et al., 1990)

Df(2L)k07245-mr31

(Roote, 2000.6.13)

Df(2L)noc11

(Yagi and Hayashi, 1997, Roote, 1996.1.11, Roote, 1996.8, Ashburner et al., 1990)

Df(2L)Prl

(BDGP Project Members, 1994-1999)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Roote, 2000.6.13)

(Rodriguez et al., 1996, Kania et al., 1995, Ashburner et al., 1990)

Df(2L)RA5

(Ashburner et al., 1990)

Df(2L)rd9

(Furukawa et al., 1992, Ashburner et al., 1990)

Df(2L)RM5

(Ashburner et al., 1990)

Df(2L)RN2

(Ashburner et al., 1990)

Df(2L)Sco^rv16

(Ashburner et al., 1990)

Df(2L)Sco^rv18

(Ashburner et al., 1990)

Df(2L)Sco^rv19

(Ashburner et al., 1990)

Df(2L)Sco^rv25

(Ashburner et al., 1990)

Df(2L)TE35BC-7

(Furukawa et al., 1992)

Df(2L)TE35BC-28

(Furukawa et al., 1992)

Df(2L)TE35D-1

(Ashburner et al., 1990)

Df(2L)TE35D-2

(Yagi and Hayashi, 1997)

Df(2L)TE35D-3

(Ashburner et al., 1990)

Df(2L)TE35D-14

(Ashburner et al., 1990)

Df(2L)TE35D-19

(Ashburner et al., 1990)

Df(2L)TE35D-21

(Yagi and Hayashi, 1997)

Df(2L)TE35D-22

(Cai et al., 2001, Ashburner et al., 1990)

Df(2L)TW50

(BDGP Project Members, 1994-1999)

Df(2R)50C-38

(BDGP Project Members, 1994-1999)

Df(2R)50C-45

(BDGP Project Members, 1994-1999)

Df(2R)50C-101

(BDGP Project Members, 1994-1999)

Df(2R)50C-102

(BDGP Project Members, 1994-1999)

Df(2R)CX1

(BDGP Project Members, 1994-1999)

In(2LR)Sco^rv1-DV7

(Ashburner et al., 1990)

T(2;3)Sco^rv7

(Ashburner et al., 1990)

Duplicated in

Dp(2;1)Sco^rv23

(Ashburner et al., 1990)

Dp(2;2)TE35B-54^L

(Ashburner et al., 1990)

Dp(2;3)osp³

(Ashburner et al., 1990)

In(2L)C163.41^LC158^R

(Ashburner et al., 1990)

In(2L)Sco^rv17LC158^R

(Ashburner et al., 1990)

Not duplicated in

Dp(2;2)GYL

(Ashburner et al., 1990)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

lethal, with Scer\GAL4^en-e16E

esg^EP633

lethal, with Scer\GAL4^hs.2sev

lethal (with esg^35Ce-3)

esg^L4

lethal (with esg^L4)

esg^35Ce-3

lethal | male limited, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

lethal | male limited | cold sensitive, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

lethal | pupal stage, with Scer\GAL4^pnr-MD237

esg^GD1437

lethal | recessive, with Scer\GAL4^- :

esg^EP2159

lethal - all die before end of embryonic stage | recessive

lethal - all die before end of larval stage | heat sensitive, with Scer\GAL4^l(1)BP-1

esg^UAS.cFa

lethal - all die before end of larval stage | recessive

lethal - all die before end of pupal stage, with Scer\GAL4^L4, esg^HMS00025

esg^L4

lethal - all die before end of pupal stage, with Scer\GAL4^L4, esg^L4

esg^HMS00025

lethal - all die before end of pupal stage | recessive

esg^P1

lethal - all die during pupal stage, with Scer\GAL4^en-e16E

esg^JF03134

partially lethal | female limited, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

partially lethal | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

partially lethal - majority die | pupal stage, with Scer\GAL4^pnr-MD237

esg^GD1437

partially lethal - majority die | recessive, with Scer\GAL4^- :

esg^EP2408

viable

viable, with Scer\GAL4^nullo.PG

esg^HMS00025

viable, with Scer\GAL4^tin.CΔ4

esg^GD1437

Sterility

Allele

female sterile | recessive

female sterile | recessive, with Scer\GAL4^- :

esg^EP2009

fertile

Other Phenotypes

Allele

chemical sensitive | dominant

decreased cell number | adult stage, with Scer\GAL4^Dl-05151-G

esg^HMS02538

decreased cell number | adult stage, with Scer\GAL4^Su(H).GBE

decreased occurrence of cell division (with esg^35Ce-3)

esg⁰⁵⁷²⁹

decreased occurrence of cell division (with esg⁰⁵⁷²⁹)

esg^35Ce-3

decreased occurrence of cell division | embryonic stage 14 (with Df(2L)ED1054)

esg^NP7011

flightless, with Scer\GAL4^Mef2.PR

esg^GD1437

gravitaxis defective

esg^c287a

increased cell number | adult stage, with Scer\GAL4^Dl-05151-G

increased cell number | adult stage, with Scer\GAL4^esg.PU

esg^HMS02538

increased cell number | larval stage

esg^GD1437

neurophysiology defective, with Scer\GAL4^elav.PLu

esg^EP2009

smell perception defective

esg^BG02354

some die during embryonic stage | recessive

some die during larval stage | heat sensitive, with Scer\GAL4^l(1)BP-1

esg^UAS.cFa

some die during larval stage | recessive

some die during pupal stage | recessive

esg^P1

visible

esg^GMR.PL

visible, with Scer\GAL4^455.2

visible, with Scer\GAL4^ap-md544

esg^EP683

visible, with Scer\GAL4^bbg-C96

esg^d05415

visible, with Scer\GAL4^elav-C155

esg^UAS.cFa

visible, with Scer\GAL4^en-e16E

visible, with Scer\GAL4^ey.PH

visible, with Scer\GAL4^pnr-MD237

esg^GD1437

visible, with Scer\GAL4^sca-537.4

visible | dominant, with Scer\GAL4^bi-omb-Gal4

esg^EP2009

visible | dominant, with Scer\GAL4^dpp.blk1

esg^EP633

visible | dominant, with Scer\GAL4^hs.2sev

esg^EP684

visible | male limited, with Scer\GAL4^Bx-MS1096

esg^GD1437

visible | recessive

visible | somatic clone, with Scer\GAL4^Act5C.PI

esg^UAS.cFa

wild-type

esg^hs.PF

Phenotype manifest in

Allele

abdomen

esg^L4

adult midgut | adult stage, with Scer\GAL4^Dl-05151-G

adult midgut | adult stage, with Scer\GAL4^esg.PU

esg^HMS02538

adult midgut | adult stage, with Scer\GAL4^Su(H).GBE

adult thorax, with Scer\GAL4^ap-md544

esg^EP683

chaeta, with Scer\GAL4^ap-md544

esg^EP683

chaeta | supernumerary, with Scer\GAL4^pnr-MD237

esg^GD1437

chordotonal organ | lateral

esg^k08104

dorsal air sac primordium tip cell | third instar larval stage | heat sensitive, with Scer\GAL4^btl.PS, Scer\GAL80^ts.αTub84B

esg^UAS.cFa

embryonic/larval dorsal branch 1

embryonic/larval dorsal branch 2

embryonic/larval dorsal branch 3

embryonic/larval dorsal branch 4

embryonic/larval dorsal branch 5

embryonic/larval dorsal branch 6

embryonic/larval dorsal branch 7

embryonic/larval dorsal branch 8

embryonic/larval dorsal branch 9

embryonic/larval dorsal branch 10

embryonic/larval dorsal trunk

esg^G66

embryonic/larval hemocyte | third instar larval stage, with Scer\GAL4^Pxn.PS

embryonic/larval salivary gland | embryonic stage, with Scer\GAL4^l(1)BP-1

esg^UAS.cFa

embryonic/larval tracheal system

esg^G66

embryonic/larval tracheal system, with Scer\GAL4^C38, Scer\GAL4^tracheal

esg^UAS.cFa

embryonic ganglion mother cell | embryonic stage 14 (with Df(2L)ED1054)

esg^NP7011

embryonic neuroblast | embryonic stage 14 (with Df(2L)ED1054)

esg^NP7011

enteroblast | adult stage, with Scer\GAL4^Su(H).GBE

enteroendocrine cell | adult stage, with Scer\GAL4^Dl-05151-G

enteroendocrine cell | adult stage, with Scer\GAL4^esg.PU

esg^HMS02538

external sensory organ, with Scer\GAL4^Eq1

esg^EPA02-050

eye

esg^GMR.PL

eye, with Scer\GAL4^elav-C155

esg^UAS.cFa

eye, with Scer\GAL4^ey.PH

eye, with Scer\GAL4^hs.2sev

esg^EP684

eye | somatic clone

esg^G66

germinal proliferation center hub

esg^L2

hub cell

esg^shof

lateral transverse muscle

esg^k04408

interommatidial bristle, with Scer\GAL4^elav-C155

esg^UAS.cFa

intestinal stem cell | adult stage, with Scer\GAL4^Dl-05151-G

esg^HMS02538

larval inner optic anlage, with Scer\GAL4^NP1233

esg^GD1437

esg^L2

leg & trichome | somatic clone, with Scer\GAL4^Act5C.PI

esg^UAS.cFa

leg | somatic clone, with Scer\GAL4^Act5C.PI

esg^UAS.cFa

leg sensillum | somatic clone, with Scer\GAL4^Act5C.PI

esg^UAS.cFa

macrochaeta

macrochaeta & scutum, with Scer\GAL4^sca-537.4

microchaeta & scutum, with Scer\GAL4^sca-537.4

nucleus (with esg^35Ce-3)

esg⁰⁵⁷²⁹

nucleus (with esg⁰⁵⁷²⁹)

esg^35Ce-3

ommatidium, with Scer\GAL4^elav-C155

esg^UAS.cFa

pigment cell

esg^GMR.PL

rhabdomere R7, with Scer\GAL4^Rh3.PP

esg^GS11431

scutellar bristle, with Scer\GAL4^455.2

esg^VS8.UAS

scutellar bristle & tormogen cell, with Scer\GAL4^455.2

esg^UAS.cFa

scutellar bristle & trichogen cell, with Scer\GAL4^455.2

esg^UAS.cFa

secondary pigment cell | somatic clone

esg^G66

sternite

esg^unspecified

tergite

esg^unspecified

tertiary pigment cell | somatic clone

esg^G66

testis (with esg^35Ce-1)

esg⁰⁵⁷²⁹

testis (with esg⁰⁵⁷²⁹)

esg^35Ce-1

thecogen cell, with Scer\GAL4^sca-537.4

esg^EP684

tracheal air sac | third instar larval stage | heat sensitive, with Scer\GAL4^btl.PS, Scer\GAL80^ts.αTub84B

esg^UAS.cFa

tracheal system, with Scer\GAL4^C38

esg^UAS.cFa

tracheal system, with Scer\GAL4^tracheal

esg^UAS.cFa

ventral thoracic disc | somatic clone

esg^G66

visceral muscle fiber

esg^L2

wing

esg^dgl

wing, with Scer\GAL4^bbg-C96

esg^d05415

wing, with Scer\GAL4^bi-omb-Gal4

esg^EP2009

wing, with Scer\GAL4^dpp.blk1

esg^EP633

wing, with Scer\GAL4^en-e16E

wing (with esg^35Ce-3)

esg⁰⁵⁷²⁹

wing (with esg⁰⁵⁷²⁹)

esg^35Ce-3

wing | female limited, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

wing | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

esg^{UAS.ORF.GW.Tag:HA}

wing | male limited, with Scer\GAL4^Bx-MS1096

esg^GD1437

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (10)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\SNAI2

10 of 15

Yes

Hsap\SNAI1

6 of 15

Yes

Hsap\SNAI3

6 of 15

Yes

Hsap\SCRT1

2 of 15

Hsap\SCRT2

2 of 15

Hsap\ZNF7

1 of 15

Yes

Hsap\ZNF250

1 of 15

Hsap\ZNF410

1 of 15

Yes

Hsap\ZNF683

1 of 15

Hsap\ZNF710

1 of 15

Yes

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (8)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Snai2

10 of 15

Yes

Mmus\Snai1

7 of 15

Yes

5 of 15

3 of 15

3 of 15

1 of 15

Yes

Mmus\Zfp410

1 of 15

Yes

Mmus\Zfp647

1 of 15

Yes

Rattus norvegicus (Norway rat) (6)

Rnor\Snai1

6 of 13

Yes

Rnor\Snai2

6 of 13

Yes

Rnor\Snai3

6 of 13

Yes

Rnor\Scrt1

3 of 13

Rnor\Scrt2

3 of 13

Rnor\Zfp647

1 of 13

Yes

Xenopus tropicalis (Western clawed frog) (4)

Xtro\snai1

7 of 12

Yes

Xtro\snai2

4 of 12

Yes

Xtro\wt1

1 of 12

Yes

Xtro\znf410

1 of 12

Yes

Danio rerio (Zebrafish) (9)

Drer\snai2

9 of 15

Yes

Drer\snai1a

4 of 15

Drer\snai1b

4 of 15

Drer\snai3

4 of 15

Yes

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (7)

Cele\snai-1

8 of 15

Yes

2 of 15

1 of 15

1 of 15

1 of 15

Yes

Cele\scrt-1

1 of 15

Cele\ztf-23

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (4)

Atha\NTT

1 of 9

Yes

Atha\TFIIIA

1 of 9

Yes

Atha\WIP4

1 of 9

Yes

Atha\WIP5

1 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\YPR015C

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190D2I )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\esg

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA17666

Drosophila persimilis

Dper\GL26425

Drosophila willistoni

Dwil\GK18133

Drosophila virilis

Dvir\GJ17399

Drosophila mojavensis

Dmoj\GI17894

Drosophila grimshawi

Dgri\GH13754

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508IO )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17007464

Musca domestica

House fly

Mdoa\17015560

Glossina morsitans

Tsetse fly

Gmor\GMOY006889

Glossina morsitans

Tsetse fly

Gmor\GMOY000167

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_07350

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_07193

Mayetiola destructor

Hessian fly

Mdes\Mdes010188

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W097C )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA006230

Danaus plexippus

Monarch butterfly

Dple\DPOGS214187-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL002306

Apis florea

Little honeybee

Aflo\5967450868

Apis mellifera

Western honey bee

Amel\GB53867

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP21695

Bombus terrestris

Buff-tailed bumblebee

Bter\15205202

Linepithema humile

Argentine ant

Lhum\LH22120

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:00183a

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG019581

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_07640

Tribolium castaneum

Red flour beetle

Tcas\esg

Pediculus humanus

Human body louse

Phum\PHUM091060

Rhodnius prolixus

Kissing bug

Rpro\RPRC005707

Cimex lectularius

Bed bug

Clec\CLEC007039

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI006384

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_04992

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X093K )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR001314

Strigamia maritima

European centipede

Smar\SMAR001730

Ixodes scapularis

Black-legged tick

Isca\ISCW012727

Stegodyphus mimosarum

African social velvet spider

Smim\KFM78385.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur13g00760

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_347447

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0Q0V )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Scratch

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-ScratchX

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Sna

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000008903

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000028912

Gallus gallus

Domestic chicken

Ggal\SNAI2

Gallus gallus

Domestic chicken

Ggal\SNAI1

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (21)

Gene Symbol

Score

Source

Alignment

wor

4 of 10

CG12605

3 of 10

Kah

3 of 10

scrt

3 of 10

sna

3 of 10

CG7691

2 of 10

Cf2

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

pad

1 of 10

Phs

1 of 10

pre-lola-G

1 of 10

wdn

1 of 10

wek

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

cancer, intestinal stem cell, APC-RAS-SNA-related

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

SNAI2; snail family transcriptional repressor 2

model of piebaldism

IEA

(FlyBase, 2019-)

model of Waardenburg syndrome type 2D

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

esg^EP684

exacerbates Alzheimer's disease

modeled by Hsap\APP^{Aβ42.GMR.T:Rnor\SS-PENK}

(Cao et al., 2008)

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SNAI2; snail family transcriptional repressor 2

10 of 15

602150

SNAI1; snail family transcriptional repressor 1

6 of 15

604238

SNAI3; snail family transcriptional repressor 3

6 of 15

612741

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

esg - CG1647

(Shokri et al., 2019)

esg - CG4956

(Shokri et al., 2019)

esg - CG6765

anti tag coimmunoprecipitation, anti tag western blot

(Shokri et al., 2019)

esg - CtBP

(Voog et al., 2014)

esg - E(spl)m8-HLH

(Shokri et al., 2019)

esg - HP1b

bimolecular fluorescence complementation, fluorescence microscopy

(Shokri et al., 2019)

esg - Ubx

(Bischof et al., 2018)

esg - abd-A

bimolecular fluorescence complementation, fluorescence microscopy

(Bischof et al., 2018)

esg - brk

immunohistochemistry, luminiscence technology

(Shokri et al., 2019)

RNA-RNA

Physical Interaction

Assay

References

esg - mir-279

(Hartl et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Li et al., 2017)

suppressible

(Sanchez-Díaz et al., 2015)

enhanceable

mir-310|mir-311|mir-312

(Sanchez-Díaz et al., 2015)

mir-310|mir-311|mir-312|mir-313

enhanceable

(Sanchez-Díaz et al., 2015)

enhanceable

mir-311

(Sanchez-Díaz et al., 2015)

suppressible

pros

(Li et al., 2017)

suppressible

(Li et al., 2017)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

ase

suppressible

(Li et al., 2017, Fuse et al., 1999)

enhanceable

(Kim et al., 2010)

suppressible

(Hekmat-Scafe et al., 2005)

gcm

suppressible

(Popkova et al., 2012)

enhanceable

(Müller et al., 2005)

jus

suppressible

(Hekmat-Scafe et al., 2005)

suppressible

(Singh et al., 2005)

enhanceable

(Singh et al., 2005)

suppressible

(Djiane et al., 2013)

osk

suppressible

(Voog et al., 2008)

para

suppressible

(Hekmat-Scafe et al., 2005)

suppressible

(Pi et al., 2011)

enhanceable

(Pena-Rangel et al., 2002)

pros

suppressible

(Hartl et al., 2011)

suppressible

(Li et al., 2017)

upd1

suppressible