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Gene Dmel\Catsup

General Information
Symbol	Dmel\Catsup	Species	D. melanogaster
Name	Catecholamines up	Annotation symbol	CG10449
Feature type	protein_coding_gene	FlyBase ID	FBgn0002022
Gene Model Status	Current	Stock availability	10 publicly available
Also Known As	l(2)37Bc, Bc
Genomic Location
Chromosome (arm)	2L	Recombination map	2-53.9
Cytogenetic map	37B11-37B11	Sequence location	2L:19,041,862..19,043,614 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Catecholamines up is referred to in FlyBase by the symbol Dmel\Catsup (CG10449, FBgn0002022). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: enzyme regulator activity. There is experimental evidence that it is involved in the biological process: regulation of catecholamine metabolic process; ovarian nurse cell to oocyte transport; border follicle cell migration; regulation of epithelial cell migration, open tracheal system. 65 alleles are reported. The phenotypes of these alleles are annotated with: organ system; multicellular structure; acellular anatomical structure; organ system subdivision; adult segment; sense organ; adult; tracheal system; embryonic/larval hemocoel; adult cuticle; external compound sense organ. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc/iron permease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult midgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627458_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Catsup. Gene sequence location is 2L:19041862..19043614.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	l(2)37Bc Larval lethal. l(2)37Bc1 produces many dead collapsed larvae at 48 h; l(2)37Bc20 displays small, still-living larvae at 144 h; l(2)37Bc11 pupal lethal with melanized puparia and pharate adults, with incomplete head and thoracic cuticle, no abdominal cuticle, and no eyes or bristles. Melanotic tumors in l(2)37Bc9/l(2)37Bc20 and l(2)37Bc9/l(2)37Bcfs1 adults.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 37B11-37B11   Limits computationally determined from genome sequence between P{lacW}l(2)37Dbk16106&P{lacW}Catsupk05424 and P{lacW}Ddck02104
Experimentally Determined Cytological Location
Cytogenetic map Notes References 37B7-37B10   (determined by in situ hybridisation)   (Spradling et al., 1999) 37B10-37B10   (determined by in situ hybridisation)   (Wright, 1991) 37B8-37B12   37B7--10   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	2-53.9
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Catsup for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Catsup-RA FBtr0081143  NM_080192   1698   449
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Catsup-PA   FBpp0080687   48.7   449   6.87     NP_524931   AAF53744
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc/iron permease (IPR003689)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA536281   AA816541   AA817564   AA940755   AA950040   AA950153   AA950354   AE014134 AAF53744   AF216584 AAF37226   AI108788   AI108794   AI108975   AI455330   AI455732   AQ025760   AY058528 AAL13757   BF494698   BG637374   BG641380   BI170684   BI212344   BI212959   BI228092   BI231437   BI236022   BI240441   BI356201   BI361637   BI362215   BI362339   BI362560   BI362561   BI362948   BI368890   BI374085   BI639757   BP541863   CA804332   CK658279   CO182625   CO185151   CO189824   CO303996   CO311946   CO322789   CO328507   CO331646   CO336503   CO338118   CZ475990   DQ375815 ABD37706   DQ375816 ABD37707   DQ375817 ABD37708   DQ375818 ABD37709   DQ375819 ABD37710   DQ375820 ABD37711   DQ375821 ABD37712   DQ375822 ABD37713   DQ375823 ABD37714   DQ375824 ABD37715   DQ375825 ABD37716   DQ375826 ABD37717   DQ375827 ABD37718   DQ375828 ABD37719   DQ375829 ABD37720   DQ375830 ABD37721   DQ375831 ABD37722   DQ375832 ABD37723   DQ375833 ABD37724   DQ375834 ABD37725   DQ375835 ABD37726   DQ375836 ABD37727   DQ375837 ABD37728   DQ375838 ABD37729   DQ375839 ABD37730   DQ375840 ABD37731   DQ375841 ABD37732   DQ375842 ABD37733   DQ375843 ABD37734   DQ375844 ABD37735   DQ375845 ABD37736   DQ375846 ABD37737   DQ375847 ABD37738   DQ375848 ABD37739   DQ375849 ABD37740   DQ375850 ABD37741   DQ375851 ABD37742   DQ375852 ABD37743   DQ375853 ABD37744   DQ375854 ABD37745   DQ375855 ABD37746   DQ375856 ABD37747   DQ375857 ABD37748   DQ375858 ABD37749   DQ375859 ABD37750   DQ375860 ABD37751   DQ375861 ABD37752   DQ375862 ABD37753   DQ375863 ABD37754   DQ375864 ABD37755   DQ375865 ABD37756   DQ375866 ABD37757   DQ375867 ABD37758   DQ375868 ABD37759   DQ375869 ABD37760   DQ375870 ABD37761   DQ375871 ABD37762   DQ375872 ABD37763   DQ375873 ABD37764   DQ375874 ABD37765   DQ375875 ABD37766   DQ375876 ABD37767   DQ375877 ABD37768   DQ375878 ABD37769   DQ375879 ABD37770   DQ375880 ABD37771   DQ375881 ABD37772   DQ375882 ABD37773   DQ375883 ABD37774   DQ375884 ABD37775   DQ375885 ABD37776   DQ375886 ABD37777   DQ375887 ABD37778   DQ375888 ABD37779   DQ375889 ABD37780   DQ375890 ABD37781   DQ375891 ABD37782   DQ375892 ABD37783   DQ375893 ABD37784   DQ375894 ABD37785   DQ375895 ABD37786   DQ375896 ABD37787   DQ375897 ABD37788   DQ375898 ABD37789   DQ375899 ABD37790   DQ375900 ABD37791   DQ375901 ABD37792   DQ375902 ABD37793   DQ375903 ABD37794   DQ375904 ABD37795   DQ375905 ABD37796   DQ375906 ABD37797   DQ375907 ABD37798   DQ375908 ABD37799   DQ375909 ABD37800   DQ375910 ABD37801   DQ375911 ABD37802   DQ375912 ABD37803   DQ375913 ABD37804   DQ375914 ABD37805   DQ375915 ABD37806   DQ375916 ABD37807   DQ375917 ABD37808   DQ375918 ABD37809   DQ375919 ABD37810   DQ375920 ABD37811   DQ375921 ABD37812   DQ375922 ABD37813   DQ375923 ABD37814   DQ375924 ABD37815   DQ375925 ABD37816   DQ375926 ABD37817   DQ375927 ABD37818   DQ375928 ABD37819   DQ375929 ABD37820   DQ375930 ABD37821   DQ375931 ABD37822   DQ375932 ABD37823   DQ375933 ABD37824   DQ375934 ABD37825   DQ375935 ABD37826   DQ375936 ABD37827   DQ375937 ABD37828   DQ375938 ABD37829   DQ375939 ABD37830   DQ375940 ABD37831   DQ375941 ABD37832   DQ375942 ABD37833   DQ375943 ABD37834   DQ375944 ABD37835   DQ375945 ABD37836   DQ375946 ABD37837   DQ375947 ABD37838   DQ375948 ABD37839   DQ375949 ABD37840   DQ375950 ABD37841   DQ375951 ABD37842   DQ375952 ABD37843   DQ375953 ABD37844   DQ375954 ABD37845   DQ375955 ABD37846   DQ375956 ABD37847   DQ375957 ABD37848   DQ375958 ABD37849   DQ375959 ABD37850   DQ375960 ABD37851   DQ375961 ABD37852   DQ375962 ABD37853   DQ375963 ABD37854   DQ375964 ABD37855   DQ375965 ABD37856   DQ375966 ABD37857   DQ375967 ABD37858   DQ375968 ABD37859   DQ375969 ABD37860   DQ375970 ABD37861   DQ375971 ABD37862   DQ375972 ABD37863   DQ375973 ABD37864   DQ375974 ABD37865   DQ375975 ABD37866   DQ375976 ABD37867   DQ375977 ABD37868   DQ375978 ABD37869   DQ375979 ABD37870   DQ375980 ABD37871   DQ375981 ABD37872   DQ375982 ABD37873   DQ375983 ABD37874   DQ375984 ABD37875   DQ375985 ABD37876   EC051737   EC052221   EC052769   EC056070   EC064994   EC216512   EC246531   EC248327   EC251638   EC267780   EL870401   EV596117   EV599430   FE863080
UniProtKB/Swiss-Prot	Q9V3A4
UniProtKB/TrEMBL	Q2EJN2 Q2EJJ7 Q2EJQ8 Q2EJM1 Q2EJE2 Q2EJH2 Q2EJK9 Q2EJE1 Q2EJF3 Q2EJC0 Q2EJD6 Q2EJL9 Q2EJE9 Q2EJP0 Q2EJJ6 Q2EJR1 Q2EJR7 Q2EJD8 Q2EJS1 Q2EJF2 Q2EJF5 Q2EJB7 Q2EJR6 Q2EJQ2 Q2EJM5 Q2EJQ9 Q2EJQ6 Q2EJR0 Q2EJN0 Q2EJR5 Q2EJR3 Q2EJD1 Q2EJL5 Q2EJP2 Q2EJE6 Q2EJM6 Q2EJA5 Q2EJM0 Q2EJP5 Q2EJD4 Q2EJG6 Q2EJI9 Q2EJQ4 Q2EJB1 Q2EJL0 Q2EJK8 Q2EJQ0 Q2EJB6 Q2EJQ7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   anterior endoderm anlage   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   dorsal epidermis primordium   (Fisher et al., 2012) garland cell primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) salivary gland body primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic dorsal epidermis   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval salivary gland body   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference adult stage   adult brain | restricted   (Wang et al., 2011) dopaminergic neuron | subset of adult brain   • cell body | punctate (Wang et al., 2011) dopaminergic neuron | subset of adult brain   • synapse | punctate (Wang et al., 2011)
Additional Descriptive Data
	Catsup protein is present in a punctate pattern in the cell body, axonal and dendritic synapses of neurons in the central brain. Colocalisation of Catsup protein with ple protein, or Scer\GAL4ple.PF indicates that many of these neurons are dopaminergic. Expression of Catsup protein in the synapses is indicated by coexpression with Vmat protein. (Wang et al., 2011)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
axon inferred from direct assay (Wang et al., 2011) neuronal cell body inferred from direct assay (Wang et al., 2011) synapse inferred from direct assay (Wang et al., 2011) synaptic vesicle inferred from direct assay (Wang et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult midgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body    1097.9 Larval Salivary Gland    2077.6 Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland    1424 Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland    1576.9 Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules  (805.6) Larval Fat Body  (1097.9) Larval Salivary Gland  (2077.6) Larval Trachea  (629.575) Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut  (587.4) Adult Hindgut    454.3 Adult Malpighian Tubules  (677.3) Adult Fat Body    429.6 Adult Salivary Gland  (1424) Adult Heart    434.225 Adult VirginFemale Spermatheca  (662.9) Adult InseminatedFemale Spermatheca  (736.9) Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland  (1576.9) Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body  (1097.9) Larval Salivary Gland  (2077.6) Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland  (1424) Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland  (1576.9) Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body    1097.9 Larval Salivary Gland    2077.6 Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland    1424 Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland    1576.9 Adult Carcass    400.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body    1097.9 Larval Salivary Gland    2077.6 Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland    1424 Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland    1576.9 Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules  805.6 Larval Fat Body  (1097.9) Larval Salivary Gland  (2077.6) Larval Trachea  629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut  587.4 Adult Hindgut    454.3 Adult Malpighian Tubules  677.3 Adult Fat Body    429.6 Adult Salivary Gland  (1424) Adult Heart    434.225 Adult VirginFemale Spermatheca  662.9 Adult InseminatedFemale Spermatheca  736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland  (1576.9) Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body  1097.9 Larval Salivary Gland  (2077.6) Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland  1424 Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland  1576.9 Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    306.875 Larval Midgut    386.8 Larval Hindgut    406.5 Larval Malpighian Tubules    805.6 Larval Fat Body    1097.9 Larval Salivary Gland    2077.6 Larval Trachea    629.575 Larval Carcass    497.325 Adult Head    385.6 Adult Eye    424 Adult Brain    177.5 Adult Thoracic-Abdominal Ganglion    218.2 Adult Crop    418.1 Adult Midgut    587.4 Adult Hindgut    454.3 Adult Malpighian Tubules    677.3 Adult Fat Body    429.6 Adult Salivary Gland    1424 Adult Heart    434.225 Adult VirginFemale Spermatheca    662.9 Adult InseminatedFemale Spermatheca    736.9 Adult Ovary    288.9 Adult Testis    293.5 Adult Male Accessory Gland    1576.9 Adult Carcass    400.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    385.6   NA  Eye    424   NA  Brain    177.5   306.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    218.2   NA  Crop    418.1   386.8  Midgut    587.4   406.5  Hindgut    454.3   805.6  Malpighian Tubules    677.3   1097.9  Fat Body    429.6   2077.6  Salivary Gland    1424   NA  Heart    434.225   629.575  Trachea    NA   NA  VirginFemale Spermatheca    662.9   NA  InseminatedFemale Spermatheca    736.9   NA  Ovary    288.9   NA  Testis    293.5   NA  Male Accessory Gland    1576.9   497.325  Carcass    400.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (41) central nervous system, larvae L3  (27) central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae  (30) digestive system, larvae L3 wandering  (27) digestive system, 1-day adult  (28) digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering  (46) fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering  (34) carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male  (39) accessory gland, mated 4-day male  (47) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (41) central nervous system, larvae L3  27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae  30 digestive system, larvae L3 wandering  27 digestive system, 1-day adult  28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering  (46) fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering  (34) carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male  (39) accessory gland, mated 4-day male  (47) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    41 central nervous system, larvae L3    27 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    18 head, virgin 20-day female    20 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    19 head, mated 1-day male    14 head, mated 4-day male    13 head, mated 20-day male    17 salivary gland, larvae L3 wandering    21 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    27 digestive system, 1-day adult    28 digestive system, 4-day adult    21 digestive system, 20-day adult    22 fat body, larvae L3 wandering    46 fat body, white prepupae    22 fat body, pupae P8    9 carcass, larvae L3 wandering    34 carcass, 1-day adult    17 carcass, 4-day adult    17 carcass, 20-day adult    19 ovary, virgin 4-day female    24 ovary, mated 4-day female    25 testis, mated 4-day male    39 accessory gland, mated 4-day male    47 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (84) embryo 04-06hr  (75) embryo 06-08hr  (61) embryo 08-10hr  (76) embryo 10-12hr  (98) embryo 12-14hr  (82) embryo 14-16hr  (81) embryo 16-18hr  (63) embryo 18-20hr  (38) embryo 20-22hr  (35) embryo 22-24hr  (33) larva L1  (30) larva L2  (56) larva L3 12hr old  (49) larva L3 puffstage 1-2  (55) larva L3 puffstage 3-6  (61) larva L3 puffstage 7-9  (54) white prepupae new  (55) white prepupae 12hr  (38) white prepupae 24hr  (43) pupae 2d postWPP  (40) pupae 3d postWPP  26 pupae 4d postWPP    23 adult male 01day  (39) adult male 05day  (48) adult male 30day  (47) adult female 01day  (35) adult female 05day  (45) adult female 30day  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (57) embryo 02-04hr  (84) embryo 04-06hr  (75) embryo 06-08hr  (61) embryo 08-10hr  (76) embryo 10-12hr  (98) embryo 12-14hr  (82) embryo 14-16hr  (81) embryo 16-18hr  (63) embryo 18-20hr  (38) embryo 20-22hr  (35) embryo 22-24hr  (33) larva L1  30 larva L2  (56) larva L3 12hr old  (49) larva L3 puffstage 1-2  (55) larva L3 puffstage 3-6  (61) larva L3 puffstage 7-9  (54) white prepupae new  (55) white prepupae 12hr  (38) white prepupae 24hr  (43) pupae 2d postWPP  (40) pupae 3d postWPP  26 pupae 4d postWPP    23 adult male 01day  (39) adult male 05day  (48) adult male 30day  (47) adult female 01day  (35) adult female 05day  (45) adult female 30day  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    84 embryo 04-06hr    75 embryo 06-08hr    61 embryo 08-10hr    76 embryo 10-12hr    98 embryo 12-14hr    82 embryo 14-16hr    81 embryo 16-18hr    63 embryo 18-20hr    38 embryo 20-22hr    35 embryo 22-24hr    33 larva L1    30 larva L2    56 larva L3 12hr old    49 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    61 larva L3 puffstage 7-9    54 white prepupae new    55 white prepupae 12hr    38 white prepupae 24hr    43 pupae 2d postWPP    40 pupae 3d postWPP    26 pupae 4d postWPP    23 adult male 01day    39 adult male 05day    48 adult male 30day    47 adult female 01day    35 adult female 05day    45 adult female 30day    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  (85) embryonic 1182-4H  (58) embryonic GM2  (50) embryonic Kc167  (39) embryonic S1  (70) embryonic S3  (82) leg disc CME L1  (93) wing disc CME-W2  (58) wing disc ML-DmD8  (35) wing disc ML-DmD9  (67) wing disc ML-DmD16-c3  (53) wing disc ML-DmD21  (44) wing disc ML-DmD32  (82) haltere disc ML-DmD17-c3  (41) eye-antennal disc ML-DmD11  (53) antennal disc ML-DmD20-c5  (52) mixed discs ML-DmD4-c1  (68) CNS ML-DmBG1-c1  (90) CNS ML-DmBG2-c2  (83) tumorous blood cells mbn2  (57) ovary fGS/OSS  (46) ovary OSC  26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  (85) embryonic 1182-4H  (58) embryonic GM2  (50) embryonic Kc167  (39) embryonic S1  (70) embryonic S3  (82) leg disc CME L1  (93) wing disc CME-W2  (58) wing disc ML-DmD8  (35) wing disc ML-DmD9  (67) wing disc ML-DmD16-c3  (53) wing disc ML-DmD21  (44) wing disc ML-DmD32  (82) haltere disc ML-DmD17-c3  (41) eye-antennal disc ML-DmD11  (53) antennal disc ML-DmD20-c5  (52) mixed discs ML-DmD4-c1  (68) CNS ML-DmBG1-c1  (90) CNS ML-DmBG2-c2  (83) tumorous blood cells mbn2  (57) ovary fGS/OSS  (46) ovary OSC  26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    85 embryonic 1182-4H    58 embryonic GM2    50 embryonic Kc167    39 embryonic S1    70 embryonic S3    82 leg disc CME L1    93 wing disc CME-W2    58 wing disc ML-DmD8    35 wing disc ML-DmD9    67 wing disc ML-DmD16-c3    53 wing disc ML-DmD21    44 wing disc ML-DmD32    82 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    53 antennal disc ML-DmD20-c5    52 mixed discs ML-DmD4-c1    68 CNS ML-DmBG1-c1    90 CNS ML-DmBG2-c2    83 tumorous blood cells mbn2    57 ovary fGS/OSS    46 ovary OSC    26 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  26 cold shock, 4-day adult  (27) heat shock, 4-day adult  (29) Cadmium 50 mM 6 hrs, larvae L3  (42) Cadmium 50 mM 12 hrs, larvae L3  (32) Cadmium 50 mM 48 hrs, 4-day adult  (30) Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3  (39) Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3  (32) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (27) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult  (32) Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3  (30) Rotenone 8 μg 12 hrs, larvae L3  (29) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  26 cold shock, 4-day adult  27 heat shock, 4-day adult  29 Cadmium 50 mM 6 hrs, larvae L3  (42) Cadmium 50 mM 12 hrs, larvae L3  32 Cadmium 50 mM 48 hrs, 4-day adult  30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3  (39) Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3  32 Caffeine 1.5 mg/ml 4 hrs, larvae L3  27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult  32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3  30 Rotenone 8 μg 12 hrs, larvae L3  29 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    26 cold shock, 4-day adult    27 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    42 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    39 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    32 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    20 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD23513 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002022 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10449-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Catsup Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal Catsup68E2 lethal, with Scer\GAL4Act5C.PU CatsupGD1635 lethal, with Scer\GAL4GMR.PF, Scer\GAL4ey.PH CatsupGD1635 lethal, with Scer\GAL4pnr-MD237 CatsupGD1635 lethal | larval stage Catsup9 lethal | larval stage | recessive Catsup1 lethal | male, with Scer\GAL4Bx-MS1096 CatsupGD1635 lethal | pupal stage | recessive Catsup11 lethal | recessive Catsup1 Catsup2 Catsup3 Catsup4 Catsup5 Catsup6 Catsup7 Catsup8 Catsup9 Catsup10 Catsup12 Catsup13 Catsup14 Catsup15 Catsup16 Catsup17 Catsup18 Catsup19 Catsup20 Catsup21 Catsup22 Catsup23 Catsup24 Catsup25 Catsupk05402 Catsupk05424 Catsupk05438 lethal | recessive | cold sensitive Catsupcs1 Catsupcs2 lethal | recessive | heat sensitive Catsupts1 partially lethal - majority die | female, with Scer\GAL4Bx-MS1096 CatsupGD1635 partially lethal - majority die | recessive Catsup11 Catsup19 viable Catsupfs1 Sterility Allele female fertile Catsupts1 female sterile Catsupcs1 Catsupcs2 Catsupfs1 female sterile | recessive Catsup11 Catsup14 Catsup17 Catsup19 Catsupcs1 Catsupcs2 Catsupfs1 Other Phenotypes Allele chemical resistant | adult stage | dominant Catsup26 grooming behavior defective | adult stage | dominant Catsup12 Catsup26 hyperactive | adult stage | dominant Catsup12 Catsup26 melanotic mass phenotype Catsup9 Catsup20 Catsupfs1 melanotic mass phenotype | dominant Catsup3 Catsup5 Catsup6 Catsup8 Catsup11 Catsup13 Catsup22 Catsupcs1 Catsupcs2 Catsupfs1 wild-type Catsup+t6.9 Catsup+t9.1 Phenotype manifest in Allele adult cuticle Catsup11 adult cuticle & abdomen Catsup11 adult cuticle & adult abdomen Catsup11 border follicle cell | somatic clone Catsup68E2 crystal cell Catsup1 Catsupk05424 dorsal appendage Catsupfs1 dorsal appendage | germline clone Catsup1 egg | germline clone Catsup1 embryonic/larval dorsal trunk Catsup26 embryonic/larval salivary gland | embryonic stage Catsup11 embryonic/larval tracheal system Catsup26 epidermis | pharate adult stage Catsup11 eye Catsup11 hemolymph Catsup11 macrochaeta Catsup11 macrochaeta & adult abdomen Catsup11 melanotic mass Catsup11 Catsup13 Catsup22 Catsup3 Catsup5 Catsup6 Catsup8 Catsupcs1 Catsupcs2 Catsupfs1 pupal cuticle Catsup11 tergite Catsup11 wing, with Scer\GAL4Bx-MS1096 CatsupGD1635
Classical Alleles ( 57 )
For All Classical Alleles Show
Allele of Catsup Class Mutagen Stocks Known lesion Catsup1 ethyl methanesulfonate 2 -- Catsupk05424 P-element activity 2 -- Catsupcs1 ethyl methanesulfonate gamma ray 1 -- Catsupcs2 ethyl methanesulfonate 1 -- Catsupd07915 P-element activity 1 -- CatsupNP7008 1 -- Catsup12 amorphic allele - genetic evidence ethyl methanesulfonate formaldehyde 0 Yes Catsup10 spontaneous 0 -- Catsup11 hypomorphic allele - genetic evidence ethyl methanesulfonate formaldehyde 0 -- Catsup13 ethyl methanesulfonate formaldehyde 0 -- Catsup14 ethyl methanesulfonate formaldehyde 0 -- Catsup15 ethyl methanesulfonate 0 -- Catsup16 ethyl methanesulfonate 0 -- Catsup17 ethyl methanesulfonate 0 -- Catsup18 ethyl methanesulfonate 0 -- Catsup19 ethyl methanesulfonate 0 -- Catsup20 ethyl methanesulfonate gamma ray 0 -- Catsup21 ethyl methanesulfonate gamma ray 0 -- Catsup22 ethyl methanesulfonate 0 -- Catsup23 ethyl methanesulfonate gamma ray 0 -- Catsup24 ethyl methanesulfonate gamma ray 0 -- Catsup25 ethyl methanesulfonate gamma ray 0 -- Catsup26 Delta2-3 0 Yes Catsup27 Delta2-3 0 Yes Catsup28 Delta2-3 0 Yes Catsup29 Delta2-3 0 Yes Catsup2 ethyl methanesulfonate 0 -- Catsup30 Delta2-3 0 Yes Catsup31 Delta2-3 0 Yes Catsup32 Delta2-3 0 Yes Catsup33 Delta2-3 0 Yes Catsup34 Delta2-3 0 Yes Catsup35 Delta2-3 0 Yes Catsup36 Delta2-3 0 Yes Catsup37 Delta2-3 0 Yes Catsup38 Delta2-3 0 Yes Catsup39 Delta2-3 0 Yes Catsup3 ethyl methanesulfonate 0 -- Catsup40 Delta2-3 0 Yes Catsup41 Delta2-3 0 Yes Catsup42 Delta2-3 0 Yes Catsup43 Delta2-3 0 Yes Catsup44 Delta2-3 0 Yes Catsup45 Delta2-3 0 Yes Catsup46 Delta2-3 0 Yes Catsup4 ethyl methanesulfonate 0 -- Catsup5 ethyl methanesulfonate 0 -- Catsup68E2 chemical 0 -- Catsup6 ethyl methanesulfonate 0 -- Catsup7 ethyl methanesulfonate 0 -- Catsup8 ethyl methanesulfonate 0 -- Catsup9 ethyl methanesulfonate 0 -- Catsupfs1 ethyl methanesulfonate gamma ray 0 -- Catsupk05402 P-element activity 0 Yes Catsupk05438 P-element activity 0 -- Catsupts1 ethyl methanesulfonate 0 -- Catsupunspecified 0 --
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Catsup Class Mutagen Stocks Known lesion CatsupGD1635 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CatsupKK103630 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Catsup+t6.9 in vitro construct - genomic fragment 0 Yes Catsup+t9.1 in vitro construct - genomic fragment 0 Yes CatsupB3 in vitro construct - genomic fragment 0 Yes CatsupB4 in vitro construct - genomic fragment 0 Yes CatsupB5 in vitro construct - genomic fragment 0 Yes CatsupScer\UAS.T:Zzzz\FLAG in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)BSC257 (Christensen and Cook, 2007.3.22) Df(2L)BSC341 (Christensen and Cook, 2007.10.29) Df(2L)Catsup44 (Stathakis et al., 1999) Df(2L)Catsup45 (Stathakis et al., 1999) Df(2L)Catsup46 (Stathakis et al., 1999) Df(2L)E71 (Wright et al., 1981) Df(2L)Exel6042 (Ryder, 2004.4.26) Df(2L)Exel8039 (Ryder, 2004.4.26) Df(2L)hk18 (Pentz et al., 1986, Wright, 1996) Df(2L)hk-UC1 (BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) Df(2L)hk-UC2 (Stathakis et al., 1995, Wright, 1996) Df(2L)OD15 (Stathakis et al., 1999, Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996, Thor and Thomas, 1997) Df(2L)TW50 (Spradling et al., 1999, Wright et al., 1976, BDGP Project Members, 1994-1999) Df(2L)TW130 (Stathakis et al., 1999, Wright et al., 1976, Wright et al., 1981, Stathakis et al., 1995, Wright, 1996) Df(2L)VA18 (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA21 (Stathakis et al., 1995, Wright, 1996) Df(2L)VA23 (Stathakis et al., 1995)
Not disrupted in	Df(2L)E55 (Stathakis et al., 1995) Df(2L)M36F-S5 (BDGP Project Members, 1994-1999) Df(2L)NST (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)Sd37 (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd57 (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd77 (Stathakis et al., 1995, Wright, 1996) Df(2L)TE37C-1 (Wright et al., 1981, Gilbert et al., 1984, Wright, 1996) Df(2L)TE37C-7 (Stathakis et al., 1995, Wright, 1996) Df(2L)TW3 (BDGP Project Members, 1994-1999, Thor and Thomas, 1997) Df(2L)TW65 (BDGP Project Members, 1994-1999) Df(2L)TW137 (BDGP Project Members, 1994-1999, Stathakis et al., 1995) Df(2L)TW203 (Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) Df(2L)VA12 (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA13 (Wright et al., 1981, Gilbert et al., 1984, Wright, 1996) Df(2L)VA17 (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) Df(2L)VA19 (Stathakis et al., 1995, Wright, 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1635} NA P{KK103630} NA P{UAS-Catsup.FLAG} NA characterization construct P{pB1} NA P{pB2} NA P{pB3} NA P{pB4} NA P{pB5} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}Catsupk05402 No P{lacW}Catsupk05424 No P{lacW}Catsupk05438 No P{lacW}l(2)SH1139SH1139 No insertion of mobile activating element P{XP}Catsupd07915 NA insertion of enhancer trap binary system P{GawB}CatsupNP7008 No miscellaneous insertions P{?lacW}Catsup28 NA P{?lacW}Catsup29 NA P{?lacW}Catsup30 NA P{?lacW}Catsup31 NA P{?lacW}Catsup32 NA P{?lacW}Catsup33 NA P{?lacW}Catsup34 NA P{?lacW}Catsup35 NA P{?lacW}Catsup36 NA P{?lacW}Catsup37 NA P{?lacW}Catsup38 NA P{?lacW}Catsup39 NA P{?lacW}Catsup40 NA P{?lacW}Catsup41 NA P{?lacW}Catsup42 NA P{?lacW}Catsup43 NA
Gene Ontology: Function, Process & Cellular Component ( 14 unique terms )
Terms Based on Experimental Evidence ( 9 terms )
Molecular Function
CV term Evidence References
enzyme regulator activity inferred from mutant phenotype (Stathakis et al., 1999)
Biological Process
CV term Evidence References
border follicle cell migration inferred from mutant phenotype (Wang et al., 2006) ovarian nurse cell to oocyte transport inferred from mutant phenotype (Schupbach and Wieschaus, 1991) regulation of catecholamine metabolic process inferred from mutant phenotype (Stathakis et al., 1999) regulation of epithelial cell migration, open tracheal system inferred from mutant phenotype (Hsouna et al., 2007)
Cellular Component
CV term Evidence References
axon inferred from direct assay (Wang et al., 2011) neuronal cell body inferred from direct assay (Wang et al., 2011) synapse inferred from direct assay (Wang et al., 2011) synaptic vesicle inferred from direct assay (Wang et al., 2011)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
metal ion transmembrane transporter activity inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
metal ion transport inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-) transmembrane transport inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to plasma membrane non-traceable author statement (Swiss-Prot Project Members, 2000.10.1) membrane inferred from electronic annotation with InterPro:IPR003689 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Catsup - Pu anti bait coimmunoprecipitation, western blot, two hybrid (Wang et al., 2011) Catsup - ple anti bait coimmunoprecipitation, western blot, two hybrid (Wang et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Catsup allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 71703 DroID - A comprehensive database of gene and protein interactions. • FBgn0002022 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 48805
Orthologs
OrthoDB Orthologs (46) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6V702X Dipteran inclusive ortholog search EOG6P5KK3 Insect inclusive ortholog search EOG6CC2X3 Arthropod inclusive ortholog search EOG6CZ8XN Metazoa inclusive ortholog search EOG680WR1
Orthologs in Drosophila Species (EOG6V702X)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Catsup     Drosophila simulans   Dsim\Catsup Y   Drosophila sechellia   Dsec\GM17316 Y   Drosophila erecta   Dere\GG21151 Y   Drosophila yakuba   Dyak\GE13224 Y   Drosophila ananassae   Dana\GF14692 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10324 Y   Drosophila persimilis   Dper\GL18911 Y   Drosophila willistoni   Dwil\GK24165 Y   Drosophila virilis   Dvir\GJ11603 Y   Drosophila mojavensis   Dmoj\GI13064 Y   Drosophila grimshawi   Dgri\GH10891 Y
Orthologs in non-Drosophila Dipterans (EOG6P5KK3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001968   Anopheles gambiae Malaria mosquito  Agam\AGAP008034   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ801598
Orthologs in non-Dipteran Insects (EOG6CC2X3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB48408   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003725   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17659   Atta cephalotes Leafcutter ant  Acep\ACEP10378   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15217   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22325   Linepithema humile Argentine ant  Lhum\LH22473   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14914   Solenopsis invicta Red fire ant  Sinv\SINV19714   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004908   Bombyx mori Silkmoth  Bmor\BGIBMGA002971   Pediculus humanus Human body louse  Phum\PHUM463380   Tribolium castaneum Red flour beetle  Tcas\TC013479
Orthologs in non-Insect Arthropods (EOG6CZ8XN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_220710   Ixodes scapularis Deer tick  Isca\ISCW017090
Orthologs in non-Arthropod Metazoa (EOG680WR1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\hke-4.2 Y Caenorhabditis elegans Nematode  Cele\C14H10.1 Y Caenorhabditis elegans Nematode  Cele\hke-4.1 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020639gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013539gn Y Danio rerio Zebrafish  Drer\slc39a13 Y Danio rerio Zebrafish  Drer\slc39a7 Y Xenopus tropicalis Western clawed frog  Xtro\slc39a7 Y Xenopus tropicalis Western clawed frog  Xtro\slc39a13 Y Gallus gallus Domestic chicken  Ggal\SLC39A13 Y Mus musculus House mouse  Mmus\Slc39a7 Y Mus musculus House mouse  Mmus\Slc39a13 Y Rattus norvegicus Norway rat  Rnor\Slc39a13 Y Rattus norvegicus Norway rat  Rnor\Slc39a7 Y Homo sapiens Human  Hsap\SLC39A7 Y Homo sapiens Human  Hsap\SLC39A13 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\SLC39A7     Hsap\SLC39A13
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\Catsup Drosophila sechellia Dsec\GM17316 Drosophila erecta Dere\GG21151 Drosophila yakuba Dyak\GE13224 Drosophila ananassae Dana\GF14692 Drosophila pseudoobscura pseudoobscura Dpse\GA10324 Drosophila persimilis Dper\GL18911 Drosophila willistoni Dwil\GK24165 Drosophila virilis Dvir\GJ11603 Drosophila mojavensis Dmoj\GI13064 Drosophila grimshawi Dgri\GH10891
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	3987 Catsup1 rdo1 hk1 pr1/CyO 10572 y1 w67c23; P{lacW}Catsupk05424/CyO
Harvard	- P{XP}Catsupd07915
Kyoto	107543 Catsup1 rdo1 hk1 pr1/CyO 105327 y* w*; P{GawB}CatsupNP7008 / CyO, P{UAS-lacZ.UW14}UW14 101392 CyO, Cy1 dplv1 pr1 cn2 / Catsupcs1 pr1 101397 CyO, Cy1 dplv1 pr1 cn2 / Catsupcs2 cn1 bw1 114343 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{lacW}Catsupk05424 P{neoFRT}40A/CyO y+
VDRC	v100095 P{KK103630}VIE-260B v7183 w1118; P{GD1635}v7183/TM3
Genomic Clones ( 2 )
	BACR04C20 BACR17A06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 56 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD23513
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03420 GH07460 GH08046 GH08058 LD02041 LD16795 LD22964 LD28882 LD29989 LD30077 LD35391 LP15104 RE12223 RE17421 RE18242 RE21906 RE25524 RE32008 RE37285 RE42292 RE45948 RE46723 RE46874 RE47155 RE47156 RE47644 RE54948 RE61602 SD12707 SD15361 SD22426
Other clones	63292 104112 214535.30 557925 Dmel_neb_013144_0904_0754 Dmel_neb_015086_0605_2389 EC23432 EC29732 EC051737 EC052221 EC052769 EC056070 EK045243 EK188910 EK227264 EK243347 EK300760 EN12650 EN16004 EP09324 ESG0113a.B21_G01 FGC006C05 IP02496 RM07167
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0002022 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 48805
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Catsup CG10449 (Bayraktaroglu, 2000.8.7) Source for merge of: Catsup l(2)k05424 (FlyBase, 1996-)
Additional comments	Source for merge of Catsup l(2)k05424 was a shared cDNA (date:030206). (FlyBase, 1996-)
Other Comments
	Catsup is a pleiotropic quantitative trait gene affecting lifespan and locomotor behaviour. (Carbone et al., 2006) Catsup mutants have significantly elevated ple enzyme activity that may arise from a post-translational modification of the ple enzyme. The hyperactivation of ple enzyme results in abnormally high levels of catecholamines, which can account for the lethality, visible phenotypes and female sterility observed in the mutants. (Stathakis et al., 1999) Mutations in Catsup exhibit morphological defects of the cuticle. Catsup is essential for catecholamine metabolism in cuticle formation. Null and weak alleles of Catsup are semidominant larval lethal that produce variable and pleiotropic phenotypes including promiscuous melanisation of the salivary and lymph glands, extensive regions of incomplete epicuticle development and formation of large melanotic tumours. (Stathakis et al., 1995) Located between coordinates -74.5 and -72.4. (Stathakis et al., 1995) Mutations at the l(2)37Bc locus cause defects in midoogenesis. (Schupbach and Wieschaus, 1991)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080192 RefSeq (Proteins) • NP_524931 DDBJ / EMBL / GenBank • AA817564 AAF37226 AAF53744 AAL13757 ABD37706 ABD37707 ABD37708 ABD37709 ABD37710 ABD37711 ABD37712 ABD37713 ABD37714 ABD37715 ABD37716 ABD37717 ABD37718 ABD37719 ABD37720 ABD37721 ABD37722 ABD37723 ABD37724 ABD37725 ABD37726 ABD37727 ABD37728 ABD37729 ABD37730 ABD37731 ABD37732 ABD37733 ABD37734 ABD37735 ABD37736 ABD37737 ABD37738 ABD37739 ABD37740 ABD37741 ABD37742 ABD37743 ABD37744 ABD37745 ABD37746 ABD37747 ABD37748 ABD37749 ABD37750 ABD37751 ABD37752 ABD37753 ABD37754 ABD37755 ABD37756 ABD37757 ABD37758 ABD37759 ABD37760 ABD37761 ABD37762 ABD37763 ABD37764 ABD37765 ABD37766 ABD37767 ABD37768 ABD37769 ABD37770 ABD37771 ABD37772 ABD37773 ABD37774 ABD37775 ABD37776 ABD37777 ABD37778 ABD37779 ABD37780 ABD37781 ABD37782 ABD37783 ABD37784 ABD37785 ABD37786 ABD37787 ABD37788 ABD37789 ABD37790 ABD37791 ABD37792 ABD37793 ABD37794 ABD37795 ABD37796 ABD37797 ABD37798 ABD37799 ABD37800 ABD37801 ABD37802 ABD37803 ABD37804 ABD37805 ABD37806 ABD37807 ABD37808 ABD37809 ABD37810 ABD37811 ABD37812 ABD37813 ABD37814 ABD37815 ABD37816 ABD37817 ABD37818 ABD37819 ABD37820 ABD37821 ABD37822 ABD37823 ABD37824 ABD37825 ABD37826 ABD37827 ABD37828 ABD37829 ABD37830 ABD37831 ABD37832 ABD37833 ABD37834 ABD37835 ABD37836 ABD37837 ABD37838 ABD37839 ABD37840 ABD37841 ABD37842 ABD37843 ABD37844 ABD37845 ABD37846 ABD37847 ABD37848 ABD37849 ABD37850 ABD37851 ABD37852 ABD37853 ABD37854 ABD37855 ABD37856 ABD37857 ABD37858 ABD37859 ABD37860 ABD37861 ABD37862 ABD37863 ABD37864 ABD37865 ABD37866 ABD37867 ABD37868 ABD37869 ABD37870 ABD37871 ABD37872 ABD37873 ABD37874 ABD37875 ABD37876 AF216584 AI455330 AQ025760 AY058528 CZ475990 DQ375815 DQ375816 DQ375817 DQ375818 DQ375819 DQ375820 DQ375821 DQ375822 DQ375823 DQ375824 DQ375825 DQ375826 DQ375827 DQ375828 DQ375829 DQ375830 DQ375831 DQ375832 DQ375833 DQ375834 DQ375835 DQ375836 DQ375837 DQ375838 DQ375839 DQ375840 DQ375841 DQ375842 DQ375843 DQ375844 DQ375845 DQ375846 DQ375847 DQ375848 DQ375849 DQ375850 DQ375851 DQ375852 DQ375853 DQ375854 DQ375855 DQ375856 DQ375857 DQ375858 DQ375859 DQ375860 DQ375861 DQ375862 DQ375863 DQ375864 DQ375865 DQ375866 DQ375867 DQ375868 DQ375869 DQ375870 DQ375871 DQ375872 DQ375873 DQ375874 DQ375875 DQ375876 DQ375877 DQ375878 DQ375879 DQ375880 DQ375881 DQ375882 DQ375883 DQ375884 DQ375885 DQ375886 DQ375887 DQ375888 DQ375889 DQ375890 DQ375891 DQ375892 DQ375893 DQ375894 DQ375895 DQ375896 DQ375897 DQ375898 DQ375899 DQ375900 DQ375901 DQ375902 DQ375903 DQ375904 DQ375905 DQ375906 DQ375907 DQ375908 DQ375909 DQ375910 DQ375911 DQ375912 DQ375913 DQ375914 DQ375915 DQ375916 DQ375917 DQ375918 DQ375919 DQ375920 DQ375921 DQ375922 DQ375923 DQ375924 DQ375925 DQ375926 DQ375927 DQ375928 DQ375929 DQ375930 DQ375931 DQ375932 DQ375933 DQ375934 DQ375935 DQ375936 DQ375937 DQ375938 DQ375939 DQ375940 DQ375941 DQ375942 DQ375943 DQ375944 DQ375945 DQ375946 DQ375947 DQ375948 DQ375949 DQ375950 DQ375951 DQ375952 DQ375953 DQ375954 DQ375955 DQ375956 DQ375957 DQ375958 DQ375959 DQ375960 DQ375961 DQ375962 DQ375963 DQ375964 DQ375965 DQ375966 DQ375967 DQ375968 DQ375969 DQ375970 DQ375971 DQ375972 DQ375973 DQ375974 DQ375975 DQ375976 DQ375977 DQ375978 DQ375979 DQ375980 DQ375981 DQ375982 DQ375983 DQ375984 DQ375985 Entrez Gene - A searchable database of RefSeq genes. • 48805 UniProtKB/Swiss-Prot • Q9V3A4 UniProtKB/TrEMBL • Q2EJA5 Q2EJB1 Q2EJB6 Q2EJB7 Q2EJC0 Q2EJD1 Q2EJD4 Q2EJD6 Q2EJD8 Q2EJE1 Q2EJE2 Q2EJE6 Q2EJE9 Q2EJF2 Q2EJF3 Q2EJF5 Q2EJG6 Q2EJH2 Q2EJI9 Q2EJJ6 Q2EJJ7 Q2EJK8 Q2EJK9 Q2EJL0 Q2EJL5 Q2EJL9 Q2EJM0 Q2EJM1 Q2EJM5 Q2EJM6 Q2EJN0 Q2EJN2 Q2EJP0 Q2EJP2 Q2EJP5 Q2EJQ0 Q2EJQ2 Q2EJQ4 Q2EJQ6 Q2EJQ7 Q2EJQ8 Q2EJQ9 Q2EJR0 Q2EJR1 Q2EJR3 Q2EJR5 Q2EJR6 Q2EJR7 Q2EJS1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc/iron permease (IPR003689) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD23513
Linkouts
	BioGRID - A database of protein and genetic interactions • 71703 DroID - A comprehensive database of gene and protein interactions. • FBgn0002022 DRSC - Results from RNAi screens. • FBgn0002022 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0002022 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10449-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0002022 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 48805 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 48805 modMine - Data generated by the modENCODE project. • FBgn0002022
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	Bc (Thor and Thomas, 1997, Wright, 1996, McCrady and Tolin, 1994) Catecholamines up (Edwards et al., 2006) Catsup (Jordan et al., 2006, Ferdousy et al., 2007, Inamdar et al., 2007, Carbone et al., 2006, McCrady and Tolin, 1994, Christensen and Cook, 2007.3.22, Christensen and Cook, 2007.10.29, Wang et al., 2011, Wright and O'Donnell, 2008, Ferdousy et al., 2008, Dietzl et al., 2007, Carrasco-Rando and Ruiz-Gómez, 2008, Chaudhuri et al., 2007, Harbison et al., 2009, Wicker-Thomas and Hamann, 2008, Hsouna et al., 2007, Roshina and Pasyukova, 2007, Gutiérrez et al., 2010, Loeschcke et al., 2011, Inamdar et al., 2012) catsup (Norry et al., 2009, Wang et al., 2006, Lye et al., 2012) CG10449 (Keleman et al., 2009.8.5) dCATSUP (Mathews et al., 2005) fs(2)ltoQT50   l(2)37Bc (Thor et al., 1999, Stathakis et al., 1995, Lemaitre et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981, Wright, 1987) l(2)E13 (Wright et al., 1976, ) l(2)k05402 (Mesilaty-Gross et al., 1999) l(2)k05424 (Spradling et al., 1999, )
Name Synonym	Catecholamines up (Edwards et al., 2006, Jordan et al., 2006, Carbone et al., 2006, Wright and O'Donnell, 2008, Ferdousy et al., 2008, Harbison et al., 2009, Hsouna et al., 2007, Gutiérrez et al., 2010, Inamdar et al., 2012) catsup (Edwards and Mackay, 2004)
Secondary FlyBase IDs
	FBgn0022172 FBgn0032743
References ( 87 )
Generate a list of	All references relating to this gene ( 87 )
List References by type	Research paper  ( 35 ) Supplementary material  ( 5 ) Review  ( 2 ) Personal communication to FlyBase  ( 12 ) Abstract  ( 26 ) FlyBase analysis  ( 2 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 ) Book  ( 1 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 5 )
	Lye et al., 2013, J. Biol. Inorg. Chem. 18(3): 323--332 In vivo zinc toxicity phenotypes provide a sensitized background that suggests zinc transport activities for most of the Drosophila Zip and ZnT genes. [FBrf0220942] Inamdar et al., 2012, Parkinsons Dis. 2012: 938528 The Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds. [FBrf0219235] Lye et al., 2012, J. Exp. Biol. 215(18): 3254--3265 Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster. [FBrf0219291] Loeschcke et al., 2011, J. Insect Physiol. 57(9): 1227--1231 Consistent effects of a major QTL for thermal resistance in field-released Drosophila melanogaster. [FBrf0215035] Wang et al., 2011, J. Neurochem. 119(6): 1294--1305 Catecholamines up integrates dopamine synthesis and synaptic trafficking. [FBrf0216854] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...